Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(63 productos)
- Hedgehog / Smoothened(49 productos)
- Hippo pathway(7 productos)
- JAK(243 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(61 productos)
- STAT(100 productos)
- Células madre(186 productos)
- TGF-beta / Smad(60 productos)
- Wnt / beta-catenina(61 productos)
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Se han encontrado 470 productos de "Células madre y Derivados"
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JAK3i
CAS:JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.Fórmula:C18H15FN4O3Pureza:98.61% - 99.81%Forma y color:SolidPeso molecular:354.34JAK-IN-14
CAS:JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.Fórmula:C19H15FN4OPureza:98.27%Forma y color:SolidPeso molecular:334.35Ref: TM-T9764
1mg81,00€5mg170,00€1mL*10mM (DMSO)178,00€10mg268,00€25mg555,00€50mg888,00€100mg1.414,00€200mg1.882,00€TGFβRI-IN-1
CAS:TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII,Fórmula:C20H14D3N5O2Pureza:98%Forma y color:SolidPeso molecular:362.4Tyk2-IN-5
CAS:Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).Fórmula:C21H19FN8O2Pureza:98%Forma y color:SolidPeso molecular:434.43CIA-1 hcl(452087-38-6 Free base)
CAS:CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety ofFórmula:C17H20ClN3O2SPureza:99.02%Forma y color:SolidPeso molecular:365.88ELN318463
CAS:ELN 318463 selectively inhibits γ-secretase; EC50: 12 nM (PS1), 656 nM (PS2); 51x more selective for PS1; targets APP.Fórmula:C19H20BrClN2O3SPureza:98%Forma y color:SolidPeso molecular:471.8Peficitinib hydrochloride
CAS:Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).Fórmula:C18H23ClN4O2Forma y color:SolidPeso molecular:362.86Lorpucitinib
CAS:Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.Fórmula:C22H28N6O2Pureza:99.72%Forma y color:SolidPeso molecular:408.5JAK3-IN-12
CAS:JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.Fórmula:C19H19N5O4SForma y color:SolidPeso molecular:413.45RR-11a analog
CAS:RR-11a (aza-peptide) inhibits asparaginyl endopeptidase: IC50 - 4.5 nM (T. Vaginalis, I. ricinus), 31 nM (S. mansoni).Fórmula:C22H29N5O8Pureza:98.80%Forma y color:SolidPeso molecular:491.49Ref: TM-T12770
1mg152,00€5mg364,00€1mL*10mM (DMSO)394,00€10mg565,00€25mg1.044,00€50mg1.773,00€100mg2.602,00€LY-411575 isomer 1
CAS:LY-411575 isomer 1 is a potent γ-secretase inhibitor. LY-411575 isomer 1 is an isomer of LY411575.Fórmula:C26H23F2N3O4Pureza:98%Forma y color:SolidPeso molecular:479.48BPN-15606
CAS:BPN-15606, an oral γ-secretase modulator, reduces Aβ42/Aβ40 with IC50 of 7/17 nM; promising PK/PD, lowers Aβ in rodent CNS.Fórmula:C23H23FN6OForma y color:SolidPeso molecular:418.47Yhhu-3792
CAS:Yhhu-3792 activates Notch, boosts Hes3/Hes5, enhances NSC renewal, expands NSC pool, and may improve memory.Fórmula:C24H24N4O2Forma y color:SolidPeso molecular:400.47(2R,5S)-Ritlecitinib
CAS:(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].Fórmula:C15H19N5OForma y color:SolidPeso molecular:285.34JAK-2/3-IN-2
CAS:JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 & JAK3 inhibitor with IC50s of 23.85 nM (JAK2) & 18.9 nM (JAK3).Fórmula:C19H19ClN2OSForma y color:SolidPeso molecular:358.89JAK-IN-11
CAS:JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Fórmula:C23H22FN5O4SPureza:99.75%Forma y color:SolidPeso molecular:483.52OICR-0547
CAS:OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.Fórmula:C28H29F3N4O4Pureza:98%Forma y color:SolidPeso molecular:542.55JAK-IN-21
CAS:JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively.Fórmula:C19H16N8OPureza:99.87%Forma y color:SolidPeso molecular:372.38MSC-4106
CAS:MSC-4106, an oral YAP/TAZ-TEAD inhibitor, blocks TEAD1/3 auto-palmitoylation and suppresses NCI-H226 tumors.Fórmula:C18H12F3N3O2Pureza:99.89%Forma y color:SoildPeso molecular:359.3Ref: TM-T60148
1mg90,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg358,00€25mg597,00€50mg850,00€100mg1.153,00€200mg1.549,00€CID-5056270
CAS:CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, vulvar cancer, penile cancer, Burkitt's lymphoma
Fórmula:C17H13N3O3SPureza:99.6%Forma y color:SolidPeso molecular:339.37
