Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(63 productos)
- Hedgehog / Smoothened(49 productos)
- Hippo pathway(7 productos)
- JAK(243 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(61 productos)
- STAT(100 productos)
- Células madre(185 productos)
- TGF-beta / Smad(60 productos)
- Wnt / beta-catenina(61 productos)
Mostrar 2 subcategorías más
Se han encontrado 470 productos de "Células madre y Derivados"
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ABC1183
CAS:ABC1183, an oral diaminothiazole, inhibits GSK3α/β, CDK9, hinders cancer cell growth, induces G2/M arrest, and modulates phosphorylation.
Fórmula:C18H14N4OSPureza:98.92%Forma y color:SolidPeso molecular:334.39Izencitinib
CAS:Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Fórmula:C22H26N8Pureza:99.82%Forma y color:SolidPeso molecular:402.50Ref: TM-T35898
1mg84,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg567,00€50mg888,00€100mg1.431,00€200mg1.963,00€Butyzamide
CAS:Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.Fórmula:C29H32Cl2N2O5SPureza:99.39% - 99.83%Forma y color:SoildPeso molecular:591.55Ref: TM-T67894
1mg149,00€5mg253,00€1mL*10mM (DMSO)329,00€10mg371,00€25mg573,00€50mg862,00€100mg1.305,00€200mg1.755,00€STS-E412
CAS:STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.Fórmula:C15H15ClN4O2Pureza:99.01%Forma y color:SolidPeso molecular:318.76JAK-STAT-IN-1
CAS:JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.Fórmula:C21H21N5O2Pureza:99.59%Forma y color:SolidPeso molecular:375.42GSK-3β inhibitor 2
CAS:GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50
Fórmula:C14H14N4O3SPureza:99.08%Forma y color:SolidPeso molecular:318.35TT-10
CAS:TT-10 (TAZ-K) activates YAP-TEAD; useful in heart disease with cardiomyocyte loss research.
Fórmula:C11H10FN3OS2Pureza:99.29%Forma y color:SolidPeso molecular:283.35GSK-3β inhibitor 11
CAS:GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.
Fórmula:C20H15N3O4SPureza:97.33%Forma y color:SolidPeso molecular:393.42LM-41
CAS:LM-41 is a TEAD binding agent with potential anticancer activity for the study of breast cancer.Fórmula:C19H14FNO2Pureza:99.73%Forma y color:SolidPeso molecular:307.32IHMT-MST1-58
CAS:IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity.
Fórmula:C21H22N6O3SPureza:98.31% - 99.92%Forma y color:SolidPeso molecular:438.5JAK1-IN-8
CAS:JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Fórmula:C22H23FN4O3SPureza:98.4%Forma y color:SolidPeso molecular:442.51LEQ506
CAS:LEQ506 is a Smo inhibitor with IC50s of 2 nM and 4 nM for hSmo and mSmo, respectively.Fórmula:C25H32N6OPureza:99.76%Forma y color:SolidPeso molecular:432.56Ref: TM-T11838
1mg64,00€5mg145,00€1mL*10mM (DMSO)160,00€10mg210,00€25mg338,00€50mg455,00€100mg610,00€200mg823,00€FzM1
CAS:FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Fórmula:C21H16N2O2SPureza:99.37% - 99.89%Forma y color:SolidPeso molecular:360.43Ref: TM-T24076
1mg42,00€1mL*10mM (DMSO)62,00€5mg64,00€10mg99,00€25mg188,00€50mg328,00€100mg528,00€500mg1.130,00€SJ000063181
CAS:SJ000063181 activates BMP signaling (EC50 ≤1μM), usable as probe in zebrafish embryos.
Fórmula:C14H14ClFN2O2Pureza:99.94%Forma y color:SolidPeso molecular:296.72XL413 xHCl
CAS:BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215
Fórmula:C14H12ClN3O2·xHClPureza:99.37% - 99.67%Forma y color:SolidPeso molecular:326.18BMS-932481
CAS:BMS-932481 is a γ-secretase modulator.Fórmula:C24H24FN7OForma y color:SolidPeso molecular:445.49BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Fórmula:C26H26F4N4O3Forma y color:SolidPeso molecular:518.5JAK-IN-1
CAS:JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.Fórmula:C20H24N6O2Pureza:98%Forma y color:SolidPeso molecular:380.44Tubulin/JAK2-IN-1
CAS:Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significantFórmula:C22H20N6O3Forma y color:SolidPeso molecular:416.43Yhhu-3792 hydrochloride
CAS:Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].Fórmula:C24H25ClN4O2Forma y color:SolidPeso molecular:436.93
