Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(59 productos)
- Hedgehog / Smoothened(44 productos)
- Hippo pathway(6 productos)
- JAK(245 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(69 productos)
- STAT(98 productos)
- Células madre(484 productos)
- TGF-beta / Smad(58 productos)
- Wnt / beta-catenina(66 productos)
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Se han encontrado 693 productos de "Células madre y Derivados"
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ML115
CAS:<p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>Fórmula:C15H15ClN2O4Pureza:99.97%Forma y color:SolidPeso molecular:322.74BT-GSI
<p>BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.</p>Fórmula:C26H46BrN5O10P2Forma y color:SolidPeso molecular:730.52GSM-1
CAS:<p>GSM-1 is a modulator of γ-Secretase.</p>Fórmula:C26H31ClF3NO2Forma y color:SolidPeso molecular:481.98Itacnosertib (hydrocholide)
CAS:<p>Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].</p>Fórmula:C26H29ClN8OForma y color:SolidPeso molecular:505.01Brepocitinib
CAS:<p>Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).</p>Fórmula:C18H21F2N7OPureza:99.82%Forma y color:SolidPeso molecular:389.4JAK-IN-5
CAS:<p>JAK-IN-5 is a JAK inhibitor.</p>Fórmula:C27H31FN6OPureza:98.1% - 99.37%Forma y color:SolidPeso molecular:474.57MRK-560
CAS:<p>MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.</p>Fórmula:C19H17ClF5NO4S2Pureza:98.87%Forma y color:SolidPeso molecular:517.92JAK2-IN-4
CAS:<p>JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.</p>Fórmula:C23H27N5O4SPureza:98%Forma y color:SolidPeso molecular:469.56Casein Kinase II Inhibitor IV
CAS:<p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>Fórmula:C24H23N5O3Pureza:99.65% - 99.75%Forma y color:SolidPeso molecular:429.47Nezulcitinib
CAS:<p>Nezulcitinib (TD-0903) is an inhaled pan-JAK inhibitor targeting COVID-19-related acute lung injury.</p>Fórmula:C30H37N7O2Forma y color:SolidPeso molecular:527.66ABBV-712
CAS:<p>ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases</p>Fórmula:C24H28N4O5Pureza:98%Forma y color:SolidPeso molecular:452.5SWTX-143
CAS:<p>SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional</p>Fórmula:C19H18F3N3OPureza:98%Forma y color:SolidPeso molecular:361.36DT-6
CAS:<p>DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing</p>Fórmula:C89H130N20O29S2Pureza:98%Forma y color:SolidPeso molecular:2008.23JAK-IN-1
CAS:<p>JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.</p>Fórmula:C20H24N6O2Pureza:98%Forma y color:SolidPeso molecular:380.44STAT3-IN-20
CAS:<p>STAT3-IN-20 (Compound 40), with an IC50 of 0.65 μM, is a selective inhibitor targeting the SH2 domain of STAT3, thereby impeding its phosphorylation, nuclear</p>Fórmula:C30H27F4N7SPureza:98%Forma y color:SolidPeso molecular:593.64STAT6-IN-2
CAS:<p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>Fórmula:C28H31N5O2Pureza:99.67%Forma y color:SolidPeso molecular:469.58GNE-7883
CAS:<p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>Fórmula:C28H29FN6O2Pureza:97.61%Forma y color:SolidPeso molecular:500.57H-1152 dihydrochloride
CAS:<p>H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.</p>Fórmula:C16H23Cl2N3O2SPureza:99.85%Forma y color:SolidPeso molecular:392.34ROCK-IN-1
CAS:<p>ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological</p>Fórmula:C20H18FN3OPureza:>99.99%Forma y color:SolidPeso molecular:335.37Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Fórmula:C30H26O10Pureza:96.66%Forma y color:SolidPeso molecular:546.52
