Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1428 productos de "Autofagia"
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ACT-660602
CAS:<p>ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.</p>Fórmula:C20H20F6N8OSForma y color:SolidPeso molecular:534.48SMER18
CAS:<p>SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.</p>Fórmula:C16H14ClNO2Pureza:97.27%Forma y color:SolidPeso molecular:287.743HOI-BA-01
CAS:<p>3HOI-BA-01 is a mammalian targeting effective rapamycin activation inhibitor.</p>Fórmula:C19H15NO5Pureza:98%Forma y color:SolidPeso molecular:337.33PS372424
CAS:<p>PS372424 is a specific agonist of human CXCR3, with anti-inflammatory activity.</p>Fórmula:C33H44N6O4Pureza:98%Forma y color:SolidPeso molecular:588.74GPR35 agonist 1
CAS:<p>GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).</p>Fórmula:C10H4BrN5O5Pureza:98%Forma y color:SolidPeso molecular:354.07CXCR3 Antagonist 6c
CAS:<p>CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.</p>Fórmula:C30H32Cl3N5O3Forma y color:SolidPeso molecular:616.97LS2265
CAS:<p>LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.</p>Fórmula:C19H20ClNO6SPureza:98%Forma y color:SolidPeso molecular:425.88AGN 205327
CAS:<p>AGN 205327 is a potent synthetic RAR agonist,showing selective RAR activation without RXR inhibition for retinoid research.</p>Fórmula:C24H26N2O3Pureza:99.45% - 99.71%Forma y color:SolidPeso molecular:390.47LRRK2-IN-10
CAS:<p>LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2</p>Fórmula:C20H15N5OPureza:98%Forma y color:SolidPeso molecular:341.37ATG7-IN-2
CAS:<p>ATG7-IN-2 inhibits ATG7 protein with 0.089 μM IC50 and suppresses autophagy marker LC3B.</p>Fórmula:C11H16N6O7SForma y color:SolidPeso molecular:376.35rac-NBI-74330
CAS:<p>rac-NBI-74330 is an effective and selective CXCR3 antagonist.</p>Fórmula:C32H27F4N5O3Pureza:99.6%Forma y color:SolidPeso molecular:605.58AC-55649
CAS:<p>AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.</p>Fórmula:C21H26O2Pureza:99.98%Forma y color:SolidPeso molecular:310.43HF50731
CAS:<p>HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).</p>Fórmula:C26H46N4Forma y color:SolidPeso molecular:414.67ALLO-1
CAS:<p>ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.</p>Fórmula:C17H15ClN2O2Pureza:98%Forma y color:SolidPeso molecular:314.77GC7 Sulfate
CAS:<p>GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.</p>Fórmula:C8H22N4O4SPureza:99.85% - >99.99%Forma y color:SolidPeso molecular:270.35AZD8797
CAS:<p>AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.</p>Fórmula:C19H25N5OS2Pureza:98.73% - 99.68%Forma y color:SolidPeso molecular:403.56CHIR-99021 HCl
CAS:<p>CHIR-99021 HCl is a selective GSK-3α/β inhibitor (IC50: 10/6.7 nM), 500x selective over other kinases, boosts Wnt pathway, and enhances stem cell renewal.</p>Fórmula:C22H19Cl3N8Pureza:98.07% - 98.14%Forma y color:SolidPeso molecular:501.8MAPK13-IN-1
CAS:<p>MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).</p>Fórmula:C20H23N5O2Pureza:99.62%Forma y color:SolidPeso molecular:365.43Atg4B-IN-2
CAS:<p>Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.</p>Fórmula:C21H30O3Pureza:98.86%Forma y color:SolidPeso molecular:330.46Laduviglusib trihydrochloride
CAS:<p>Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.</p>Fórmula:C22H20Cl5N8Pureza:99.34%Forma y color:SolidPeso molecular:573.71
