Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1427 productos de "Autofagia"
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Dactolisib Tosylate
CAS:<p>Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor that targets PI3K and mTOR.</p>Fórmula:C37H31N5O4SPureza:99.91%Forma y color:SolidPeso molecular:641.74Acetazolamide sodium
CAS:<p>Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.</p>Fórmula:C4H5N4NaO3S2Pureza:99.71% - 99.87%Forma y color:SolidPeso molecular:244.23IT1t dihydrochloride
CAS:<p>IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.</p>Fórmula:C21H36Cl2N4S2Pureza:99.91%Forma y color:SolidPeso molecular:479.57Laduviglusib trihydrochloride
CAS:<p>Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.</p>Fórmula:C22H20Cl5N8Pureza:99.34%Forma y color:SolidPeso molecular:573.71AZD8797
CAS:<p>AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.</p>Fórmula:C19H25N5OS2Pureza:98.73% - 99.68%Forma y color:SolidPeso molecular:403.56Cysmethynil
CAS:<p>Cysmethynil is an indole-based Icmt inhibitor with antitumor activity, induces cell cycle arrest in G1 phase, and can be used for the study of solid tumors.</p>Fórmula:C25H32N2OPureza:99%Forma y color:SolidPeso molecular:376.53Rosolutamide
CAS:<p>Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.</p>Fórmula:C28H32O6Pureza:95.48% - 99.15%Forma y color:SolidPeso molecular:464.55MTK458
CAS:<p>MTK458 (EP-0035985) is a PINK1 activator with antidepressant activity for the study of Parkinson;s disease.</p>Fórmula:C17H15F3N4Pureza:98.36%Forma y color:SolidPeso molecular:332.32XRK3F2
CAS:<p>XRK3F2 inhibits p62-ZZ, counters MM's Runx2 suppression in vitro, and prompts bone growth and remodeling in vivo with tumors.</p>Fórmula:C23H24ClF2NO3Pureza:98.75% - 98.91%Forma y color:SolidPeso molecular:435.89AC-73
CAS:<p>AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.</p>Fórmula:C21H21NO2Pureza:98.95%Forma y color:SolidPeso molecular:319.4Tin-protoporphyrin IX dichloride
CAS:<p>Tin-protoporphyrin IX inhibits HO-1, enhancing chemo efficacy in mouse PDAC.</p>Fórmula:C34H32Cl2N4O4SnPureza:98%Forma y color:SolidPeso molecular:750.26CHIR-99021 HCl
CAS:<p>CHIR-99021 HCl is a selective GSK-3α/β inhibitor (IC50: 10/6.7 nM), 500x selective over other kinases, boosts Wnt pathway, and enhances stem cell renewal.</p>Fórmula:C22H19Cl3N8Pureza:98.07% - 98.14%Forma y color:SolidPeso molecular:501.8FMK 9a
CAS:<p>FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.</p>Fórmula:C23H21FN2O3Pureza:98.97%Forma y color:SolidPeso molecular:392.42Mavorixafor
CAS:<p>Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding.</p>Fórmula:C21H27N5Pureza:98.56%Forma y color:SolidPeso molecular:349.47Cytarabine hydrochloride
CAS:<p>Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase.</p>Fórmula:C9H14ClN3O5Pureza:98.46%Forma y color:White PowderPeso molecular:279.68CP-312
CAS:<p>CP-312 activates antioxidant defense, induces HMOX1, and shields human iPSC-derived cardiomyocytes from oxidative stress.</p>Fórmula:C16H12ClN3OS2Pureza:99.61%Forma y color:SolidPeso molecular:361.87Cosalane
CAS:<p>Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.</p>Fórmula:C45H60Cl2O6Pureza:99.53% - 99.78%Forma y color:SolidPeso molecular:767.86GC7 Sulfate
CAS:<p>GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.</p>Fórmula:C8H22N4O4SPureza:99.85% - >99.99%Forma y color:SolidPeso molecular:270.35Elubrixin
CAS:<p>Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM).</p>Fórmula:C17H17Cl2FN4O4SPureza:98.65% - 99.78%Forma y color:SolidPeso molecular:463.31Apostatin-1
CAS:<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Fórmula:C19H27N3OSPureza:99.31%Forma y color:SolidPeso molecular:345.5
