DHFR
La dihidrofolato reductasa (DHFR) es una enzima que desempeña un papel crucial en el ciclo del folato, esencial para la síntesis, reparación y metilación del ADN. Los inhibidores de DHFR se utilizan ampliamente como agentes quimioterapéuticos en el tratamiento del cáncer y las enfermedades autoinmunes debido a su capacidad para inhibir la proliferación celular. En CymitQuimica, ofrecemos una variedad de inhibidores de DHFR para apoyar su investigación en terapia contra el cáncer, inmunología y biología molecular.
Se han encontrado 34 productos de "DHFR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
P 218
CAS:P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.Fórmula:C18H25ClN4O4Pureza:98.83%Forma y color:SoildPeso molecular:396.87Diaveridine
CAS:Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide.Fórmula:C13H16N4O2Pureza:99.10%Forma y color:White SolidPeso molecular:260.29Pyrimethamine
CAS:Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.Fórmula:C12H13ClN4Pureza:99.67%Forma y color:CrystalsPeso molecular:248.71Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Fórmula:C20H21N5O6Pureza:98.1% - 99.92%Forma y color:Similar To White PowderPeso molecular:427.41Sulfameter
CAS:<p>Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.</p>Fórmula:C11H12N4O3SPureza:99.46% - 99.90%Forma y color:Crystalline SolidPeso molecular:280.34-O-Methyldopamine hydrochloride
CAS:Compound PDK0318, with CAS No. 645-33-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0318 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C9H13NO2Peso molecular:167.2DHFR-IN-11
DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.Forma y color:Odour SolidDHFR-IN-20
DHFR-IN-20 (Compound LA1) is an inhibitor of dihydrofolate reductase (DHFR) targeting the malignant strains of the malaria parasite. It exhibits inhibition constants (Kis) of 0.16 nM, 0.30 nM, and 6.6 nM for PfDHFR-WT, PfDHFR-QM, and HsDHFR, respectively. Additionally, DHFR-IN-20 demonstrates antimalarial activity, with IC50 values of 1.4 nM against parasites carrying the wild-type (TM4/8.2) PfDHFR enzyme and 1.6 μM against those with the quadruple mutation (V1/S)PfDHFR.Forma y color:Odour SolidDHFR-IN-18
DHFR-IN-18 (compound 19D) is a DHFR inhibitor utilized in leukemia-related research.Fórmula:C24H22ClN7Peso molecular:443.16252EGFR/DHFR-IN-1
EGFR/DHFR-IN-1 (Compound 10e) is a dual inhibitor of EGFR and DHFR, with IC50 values of 0.151 µM and 0.541 µM, respectively. It induces cell cycle arrest in the G0-G1 and S phases.Fórmula:C24H26N4O5S2Peso molecular:514.13446DHFR-IN-21
DHFR-IN-21 (compound 5p) is an inhibitor of dihydrofolate reductase.Forma y color:Odour SolidEGFR/HER2/DHFR-IN-2
<p>EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively.</p>Pureza:98%Forma y color:Odour SolidCB 3705
CAS:CB 3705 is a bio-active chemical.Fórmula:C21H21N5O6Forma y color:SolidPeso molecular:439.42DHFR-IN-16
DHFR-IN-16 (compound 8d) is an inhibitor of dihydrofolate reductase (DHFR) with an IC50 of 0.199 μM, and is valuable for anti-infection research.Fórmula:C32H34N4O4SPeso molecular:570.23008Anti-Dihydrofolate reductase Antibody (2V859)
Anti-Dihydrofolate reductase Antibody (2V859) is an antibody targeting Dihydrofolate reductase. Anti-Dihydrofolate reductase Antibody (2V859) can be used in ELISA, WB, IHC, IP.Forma y color:Odour LiquidWR99210
CAS:WR99210 (BRL 6231 free base) is a DHFR inhibitor with antiparasitic activity.Fórmula:C14H18Cl3N5O2Pureza:98.8%Forma y color:SolidPeso molecular:394.68WR99210 hydrochloride(47326-86-3 free base)
CAS:WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.Fórmula:C14H19Cl4N5O2Pureza:97.77% - 99.8%Forma y color:SolidPeso molecular:431.14Ref: TM-T17257L
1mg65,00€5mg139,00€10mg210,00€25mg356,00€50mg525,00€100mg747,00€200mg1.008,00€1mL*10mM (DMSO)165,00€DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Fórmula:C8H7BrN4Pureza:99.521% - 99.65%Forma y color:SolidPeso molecular:239.07Piritrexim isethionate
CAS:Piritrexim isethionate, a fat-soluble DHFR inhibitor, shows efficacy in metastatic urothelial cancer with a 5-day oral regimen.Fórmula:C19H25N5O6SForma y color:SolidPeso molecular:451.49Fanotaprim
CAS:Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.Fórmula:C19H22N8OPureza:98.1%Forma y color:SolidPeso molecular:378.43Ref: TM-T36692
1mg52,00€2mg74,00€5mg116,00€10mg178,00€25mg335,00€50mg467,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)128,00€
