Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.687 productos)
- Apoptosis(6.097 productos)
- Ciclo celular / Checkpoint(4.691 productos)
- Cromatina / Epigenética(2.376 productos)
- Señalización citoesquelética(1.472 productos)
- Daño al ADN / Reparación del ADN(2.921 productos)
- Endocrinología / Hormonas(3.611 productos)
- Enzima(3.655 productos)
- GPCR / proteína G(8.755 productos)
- Inmunología e inflamación(3.765 productos)
- Virus de la gripe(298 productos)
- Señalización JAK / STAT(407 productos)
- Señalización MAPK(1.230 productos)
- Transportador de membrana / canal de iones(2.947 productos)
- Metabolismo(9.940 productos)
- Microbiología / Virología(7.347 productos)
- Neurociencia(10.240 productos)
- Otros inhibidores(36.533 productos)
- Reducción de oxidación(43 productos)
- Señalización PI3K / Akt / mTOR(1.437 productos)
- Proteasas / Proteasoma(1.675 productos)
- Células madre y Derivados(830 productos)
- Tirosina quinasa / adaptadores(2.028 productos)
- Ubiquitinación(1.682 productos)
Mostrar 16 subcategorías más
Se han encontrado 66582 productos de "Inhibidores"
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AM-3189
CAS:<p>AM-3189: potent, selective GPR40 agonist with low CNS penetration, good pharmacokinetics, and efficacy mirroring AMG 837.</p>Fórmula:C27H25ClN2O3Forma y color:SolidPeso molecular:460.95PARP1/BRD4-IN-2
PARP1/BRD4-IN-2, a potent inhibitor of PARP1 and BRD4, halts cell cycle, triggers apoptosis, and has antitumor effects on TNBC.Fórmula:C25H20N4O4Forma y color:SolidPeso molecular:440.45DBCO-Sulfo-Link-biotin
CAS:DBCO-Sulfo-Link-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].Fórmula:C31H35N5O7S2Pureza:98%Forma y color:SolidPeso molecular:653.77CB2 receptor antagonist 1
CAS:Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.Fórmula:C28H47NO3Forma y color:SolidPeso molecular:445.68U91356
CAS:U91356 is an agonist of the dopamine receptors.Fórmula:C13H17N3OPureza:98%Forma y color:SolidPeso molecular:231.29Luffariellolide
CAS:Luffariellolide is a terpene compound obtained from the marine sponge Hyrtios communis that is an HSF-PLA2 inhibitor and a RAR agonist.Fórmula:C25H38O3Pureza:98%Forma y color:SolidPeso molecular:386.57LY3154207
CAS:LY3154207: selective, potent oral human dopamine D1 receptor PAM, low agonist activity, EC50=3 nM.Fórmula:C24H29Cl2NO3Forma y color:SolidPeso molecular:450.4(Rel)-Factor B-IN-5
CAS:(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.Fórmula:C27H32N2O4Pureza:>99.99%Forma y color:SolidPeso molecular:448.55PDE-I2
CAS:PDE-I2 is a parasite schizogony inhibitor.Fórmula:C25H23N5O8Forma y color:SolidPeso molecular:521.48Murizatoclax
CAS:AMG 397 is an oral MCL1 inhibitor .Fórmula:C42H57ClN4O5SPureza:98%Forma y color:SolidPeso molecular:765.44SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Fórmula:C36H38N2O2Forma y color:SolidPeso molecular:530.7LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Fórmula:C21H11D7F3N5O3Forma y color:SolidPeso molecular:452.44MRTX849 ethoxypropanoic acid
CAS:MRTX849 is a KRAS G12C ligand and PROTAC linker for creating potent LC-2, degrading KRAS G12C with DC50 of 0.25-0.76 μM.Fórmula:C37H43ClFN7O5Forma y color:SolidPeso molecular:720.24MEIS-IN-2
MEIS-IN-2 is an inhibitor of MEIS1. MEIS-IN-2 can be used in studies of cardiac regeneration and haematopoietic stem cell (HSC) regulation.Fórmula:C23H21ClN2O4Forma y color:SolidPeso molecular:424.88AS1940477
CAS:<p>AS1940477 selectively inhibits p38 MAPK α/β, blocks proinflammatory cytokines in cells, and has anti-inflammatory effects in rats.</p>Fórmula:C24H22FN5O2Forma y color:SolidPeso molecular:431.46KRas G12C inhibitor 2
CAS:<p>KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.</p>Fórmula:C32H37N7O3Pureza:98%Forma y color:SolidPeso molecular:567.68PI3Kα-IN-8
PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM).Fórmula:C26H27BrN4O2Forma y color:SolidPeso molecular:507.42Riminkefon
CAS:<p>Riminkefon is a kappa opioid receptor agonist .</p>Fórmula:C38H57N7O6Forma y color:SolidPeso molecular:707.9I-BET282E
I-BET282E inhibits eight BET bromodomains (pIC50 6.4-7.7) with selectivity for other bromodomain proteins.Fórmula:C26H34N4O7SForma y color:SolidPeso molecular:546.64MRS2500
CAS:MRS2500 is a highly potent and selective platelet P2Y1 receptor antagonist.Fórmula:C13H18IN5O8P2Pureza:98%Forma y color:SolidPeso molecular:561.16TTK inhibitor 3
CAS:TTK inhibitor 3 is a potent and selective TTK (an essential spindle assembly checkpoint enzyme) inhibitor with an IC 50 value of 3.0 nM.Fórmula:C42H49N9O3Forma y color:SolidPeso molecular:727.9Tuberculosis inhibitor 5
Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.Fórmula:C25H18N2O2SForma y color:SolidPeso molecular:410.49CVN636
CAS:CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for humanFórmula:C19H20FNO4SForma y color:SolidPeso molecular:377.43Ledene
CAS:Ledene (Viridiflorene) is an essential oil produced by viridiflorene synthase.Fórmula:C15H24Pureza:98%Forma y color:SolidPeso molecular:204.35Bim-IN-1
Bim-IN-1 is a potent inhibitor of Bim expression with low toxicity, Bim-IN-1 reduces Bim expression levels with little inhibition of protein kinase A.Fórmula:C19H20Cl2FNO2SForma y color:SolidPeso molecular:416.34MAO-B-IN-6
MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.Forma y color:SolidAdecypenol
CAS:Adecypenol is a unique adenosine deaminase inhibitor. It shows effective inhibitory activity against calf intestinal adenosine deaminase.Fórmula:C12H16N4O4Pureza:98%Forma y color:SolidPeso molecular:280.28Flutimide
CAS:Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.Fórmula:C12H18N2O3Forma y color:SolidPeso molecular:238.28Aspochalasin M
CAS:Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.Fórmula:C24H35NO4Forma y color:SolidPeso molecular:401.54MMG-11 quarterhydrate
<p>MMG-11 quarterhydrate, a potent hTLR2 antagonist, inhibits TLR2/1 and TLR2/6 with IC50s of 1.7μM and 5.7μM; low toxicity.</p>Fórmula:C15H16O8Forma y color:SolidPeso molecular:310.78PRMT5-IN-1 hydrochloride
PRMT5 IN-1 hydrochloride is a potent PRMT5 inhibitor (IC50: 11 nM), forms covalent adduct with C449, and converts to an aldehyde in vivo.Fórmula:C19H20Cl2N4O5Forma y color:SolidPeso molecular:455.29AY 17,605
CAS:AY 17,605 is an inhibitor of bovine heart and rat brain nucleoside-3',5'- monophosphate phosphodiesterase.Fórmula:C25H36O5Forma y color:SolidPeso molecular:416.55[D-Leu-4]-OB3
CAS:[D-Leu-4]-OB3 suppresses the expression of genes associated with inflammation, proliferation, and metastasis, as well as the expression of PD-L1.Fórmula:C29H50N8O12SForma y color:SolidPeso molecular:734.82NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Fórmula:C14H9IN2O3SForma y color:SolidPeso molecular:412.2(S)-3-Hydroxy Midostaurin
CAS:(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).Fórmula:C35H30N4O5Pureza:98%Forma y color:SolidPeso molecular:586.64AGN-204396
CAS:AGN-204396 is an antagonist that selectively blocks the activity of prostamides (prostaglandin-ethanolamides).Fórmula:C32H44FN3O4Forma y color:SolidPeso molecular:553.71LpxC-IN-10
CAS:LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.Fórmula:C30H31N5O3Forma y color:SolidPeso molecular:509.6Rosiptor acetate
CAS:Rosiptor (AQX-1125) activates SHIP1, inhibits Akt, and reduces inflammation and allergy in rodents.Fórmula:C22H39NO4Pureza:98%Forma y color:Solid PowderPeso molecular:381.55IDX-320
CAS:IDX-320 is an HCV protease inhibitor.Fórmula:C37H43F3N6O7S2Forma y color:SolidPeso molecular:804.9EGFR/HER2-IN-4
EGFR/HER2-IN-4: oral, irreversible dual EGFR inhibitor (IC50: 0.6 nM), targets L858R/T790M mutations, potent anti-lung cancer effects in vivo.Forma y color:SolidEGFR-IN-35
CAS:EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.Fórmula:C25H24ClN7O2Forma y color:SolidPeso molecular:489.96TD-0212
CAS:TD-0212: Oral dual antagonist for AT1 (pKi 8.9) & NEP inhibitor (pIC50 9.2).Fórmula:C28H34FN3O4SPureza:98%Forma y color:SolidPeso molecular:527.65TrxR-IN-2
TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.Fórmula:C22H22N4O4Forma y color:SolidPeso molecular:406.43(Rac)-OSMI-1
(Rac)-OSMI-1, a racemate, inhibits OGT (IC50: 2.7 μM) affecting O-GlcNAcylation without changing surface glycans.Fórmula:C28H25N3O6S2Forma y color:SolidPeso molecular:563.64(E)-10-Hydroxynortriptyline maleate
CAS:(E)-10-Hydroxy Nortriptyline maleate, a derivative of antidepressant Nortriptyline, eases depression symptoms.Fórmula:C23H25NO5Pureza:98%Forma y color:SolidPeso molecular:395.455MDK-3298
CAS:MDK-3298 is a reversible covalent inhibitor of Mcl-1, a target of protein-protein interaction (PPI).Fórmula:C35H32BN3O7Pureza:98%Forma y color:SolidPeso molecular:617.46FT3967385
FT3967385: New USP30 inhibitor boosts mitochondrial ubiquitylation via PINK1-PARKIN.Fórmula:C21H19N5O2Forma y color:SolidPeso molecular:373.41Topoisomerase IIα-IN-4
Topoisomerase IIα-IN-4 (F2) is a non-intercalative ATP-competitive inhibitor of human DNA topoisomerase II, specifically inhibiting TopoIIα with an IC50 valueFórmula:C25H21NO2Forma y color:SolidPeso molecular:367.44SHR902275
CAS:<p>SHR902275: potent RAF inhibitor, hits RAS mutations, oral use. cRAF IC50=1.6 nM, bRAFwt IC50=10 nM, bRAFV600E IC50=5.7 nM, hinders cell growth.</p>Fórmula:C26H23F3N4O4Forma y color:SolidPeso molecular:512.48CRM1 degrader 1
<p>CRM1 degrader 1 (1l) is a low-toxic CRM1 degrader that induces apoptosis in gastric carcinoma and selectively inhibits the proliferation of gastric cancer[1].</p>Fórmula:C16H20O3Forma y color:SolidPeso molecular:260.33PGDM
CAS:PGD2 is involved in allergy, asthma, sleep, temperature regulation, inhibits clotting, and relaxes blood vessels; PGDM, its metabolite, is a biomarker.Fórmula:C16H24O7Forma y color:SolidPeso molecular:328.36SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Fórmula:C21H21N5O5SForma y color:SolidPeso molecular:455.49Ambelline
CAS:Ambelline has antitumor activity.Fórmula:C18H21NO5Pureza:98%Forma y color:SolidPeso molecular:331.36CYP1B1-IN-2
<p>CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].</p>Fórmula:C20H11F3O2Forma y color:SolidPeso molecular:340.3Pyruvate Carboxylase-IN-2
CAS:Pyruvate Carboxylase-IN-2, erianin analog, inhibits PC with IC50s of 0.065/0.097 μM in lysate/cell assays, targets HCC.Fórmula:C21H22O8Forma y color:SolidPeso molecular:402.39GSK852
GSK852 is a potent, second bromodomain (BD2)-selective, bromo and extra-terminal domain (BET) inhibitor with pIC50 of 7.9.Fórmula:C24H26N2O4Forma y color:SolidPeso molecular:406.47GSK2945 hydrochloride
<p>GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.</p>Fórmula:C20H19Cl3N2O2SForma y color:SolidPeso molecular:457.8Trk-IN-8
<p>Trk-IN-8: TRK inhibitor with IC50 of 0.42 nM (TRKA), 0.89 nM (TRKA-G595R), 1.5 nM (TRKC-G623R).</p>Fórmula:C18H16F2N6O2Forma y color:SolidPeso molecular:386.36FGFR4-IN-4
CAS:FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.Fórmula:C28H32Cl2N6O5Pureza:98%Forma y color:SolidPeso molecular:603.5Flurandrenolone Acetate
CAS:Flurandrenolone Acetate, a synthetic glucocorticoid derived from Flurandrenolide, is used to study skin issues like eczema and psoriasis.Fórmula:C26H35FO7Forma y color:SolidPeso molecular:478.55LMD-A
CAS:LMD-A, also known as CCR8 antagonist LMD-A, is a CCR8 antagonist.Fórmula:C27H32N4O4SForma y color:SolidPeso molecular:508.63Motuporin
CAS:<p>Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).</p>Fórmula:C40H57N5O10Forma y color:SolidPeso molecular:767.91PX-316
CAS:PX-316: AKT inhibitor, reduces Akt activity by 78% in HT-29 xenografts, effective against MCF-7 and HT-29 cancers, well-tolerated intravenously.Fórmula:C28H57O10PForma y color:SolidPeso molecular:584.72KR-67607
CAS:KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Fórmula:C24H29Cl2F3N4O4SForma y color:SolidPeso molecular:597.48MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Fórmula:C25H26N6O7Forma y color:SolidPeso molecular:522.51ddCTP trisodium
ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.Fórmula:C9H13N3Na3O12P3Forma y color:SolidPeso molecular:517.1Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Fórmula:C26H26FN3O4Forma y color:SolidPeso molecular:463.5MRS4458
CAS:<p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>Fórmula:C24H20F3N5O3SPureza:98%Forma y color:SolidPeso molecular:515.51VEGFR-2-IN-18
VEGFR-2-IN-18 is a potent VEGFR-2 inhibitor with a 60 nM IC50, promoting cell apoptosis and anticancer effects.Fórmula:C20H13ClN4O2Forma y color:SolidPeso molecular:376.8Rpi 856 C
CAS:Rpi 856 C is a retrovirus protease inhibitor from Streptomyces that is effective against HIV-1 and HTLV-1 proteases.Fórmula:C39H56N6O10Pureza:98%Forma y color:SolidPeso molecular:768.90GSK-3β inhibitor 6
GSK-3β inhibitor 6 is a highly potent inhibitor of GSK-3β, with an IC50 value of 24.4 μM.Fórmula:C20H17BrN4Forma y color:SolidPeso molecular:393.28KMH-233
CAS:<p>KMH-233 effectively blocks LAT1, inhibiting L-leucine uptake and cell growth, boosting betastatin and cisplatin efficacy at 25 μM.</p>Fórmula:C32H25N7O5Forma y color:SolidPeso molecular:587.58CDK4/6-IN-13
CAS:Compounds 10B and 10C: potent cdk4/6 inhibitors with low nM activity, great antiproliferative effects, excellent metabolism, and good pharmacokinetics.Fórmula:C25H29N7OForma y color:SolidPeso molecular:443.54JAK3 covalent inhibitor-1
CAS:<p>JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus kinase 3 (JAK3), possessing an IC50 of 11 nM and</p>Fórmula:C22H17FN6O2SPureza:98%Forma y color:SolidPeso molecular:448.47Luffolide
CAS:Luffolide, a Luffariella sponge metabolite, shares manoalide's anti-inflammatory traits and fully inhibits PLA2's cleavage of phosphatidylcholine.Fórmula:C27H40O6Forma y color:SolidPeso molecular:460.60Nepaprazole sodium
CAS:Nepaprazole Na (TY-11345), a proton pump inhibitor, may treat gastric ulcers; it reduces H+/K(+)-ATPase activity, with IC50 of 5.8-9.9 microM.Fórmula:C18H18N3NaO2SForma y color:SolidPeso molecular:363.41hAChE/Aβ1-42-IN-1
CAS:Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines andFórmula:C20H24N6OForma y color:SolidPeso molecular:364.44hCAII-IN-5
CAS:hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Fórmula:C29H18N2O7Forma y color:SolidPeso molecular:506.46Antileishmanial agent-4
Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].Fórmula:C17H18N4O4Forma y color:SolidPeso molecular:342.35SB 224289
CAS:SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Fórmula:C32H32N4O3Pureza:98%Forma y color:SolidPeso molecular:520.62Dazucorilant
CAS:Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.Fórmula:C29H22F4N4O3SForma y color:SolidPeso molecular:582.57BMS-986104 HCl
CAS:BMS-986104 is a potent and selective S1P1 receptor modulator.Fórmula:C22H36ClNOPureza:98%Forma y color:SolidPeso molecular:365.98PF-06380101
CAS:PF-06380101, a potent auristatin analog and Dolastatin 10 derivative, shows strong anti-tumor activity and unique ADME attributes.Fórmula:C39H62N6O6SPureza:98%Forma y color:SolidPeso molecular:743.01MCTR3
CAS:MCTR3, derived from DHA via maresin 1 in macrophages, hastens tissue healing and reduces inflammation and eicosanoids post-E. coli infection in mice.Fórmula:C25H37NO5SForma y color:SolidPeso molecular:463.63(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Fórmula:C28H35F3N4O3Forma y color:SolidPeso molecular:532.6YW3-56 (hydrochloride) (technical grade)
CAS:<p>YW3-56: PAD2 & PAD4 inhibitor (IC50 = 0.5-5 μM), halts U2OS cell growth (IC50 ~2.5 μM), reduces S-180 & MDA-MB-231 tumor growth in mice.</p>Fórmula:C27H33Cl2N5O2Forma y color:SolidPeso molecular:530.49Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Fórmula:C23H22BrN3O5Forma y color:SolidPeso molecular:500.34hMAO-B/MB-COMT-IN-2
Dual inhibitor hMAO-B/MB-COMT-IN-2 targets hMAO-B (IC50: 4.27μM) & MB-COMT (IC50: 2.69μM), aids in neurodegenerative research.Fórmula:C17H18N2O3Forma y color:SolidPeso molecular:298.348(S),15(S)-DiHETE
CAS:<p>8(S),15(S)-DiHETE, from 15(S)-HETE's oxidation by 15-LO, triggers eosinophil movement at 1.5 μM; it counteracts pain and LTB4 effects.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47Afeletecan HCl
CAS:Afeletecan (BAY 56-3722) is a water-soluble, anti-cancer camptothecin conjugated to a carbohydrate, inhibiting DNA replication and inducing apoptosis.Fórmula:C45H50ClN7O11SForma y color:SolidPeso molecular:932.44(R)-FL118
CAS:FL118 inhibits human survivinion expression and activates tumor suppressor p53 as a MOA in p53 wild-type cancer cells.Fórmula:C21H16N2O6Forma y color:SolidPeso molecular:392.36NBD-14189
CAS:NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).Fórmula:C18H16F4N4O2SForma y color:SolidPeso molecular:428.40DNA-PK-IN-9
DNA-PK-IN-9 (YK6) is a potent DNA-PK inhibitor with an IC50 of 10.47 nM, important in cancer research.Fórmula:C21H21N5O2Forma y color:SolidPeso molecular:375.42LY 254155
CAS:LY 254155, an antifolate,binds to mFBP and inhibits hGARFT with Kis of 1.7±0.1 and 2.1±0.2 nM, respectively.Fórmula:C19H23N5O6SPureza:98%Forma y color:SolidPeso molecular:449.48XR8-69
<p>XR8-69 is a SARS-CoV-2 PLpro inhibitor. XR8-69 has a low micromolar antiviral effect in SARS-CoV-2 infected human cells.</p>Fórmula:C26H30N4O2SForma y color:SolidPeso molecular:462.61GENZ-882706
CAS:<p>GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.</p>Fórmula:C26H25N5O3Pureza:98%Forma y color:SolidPeso molecular:455.51AZD2353
CAS:<p>AZD2353 is a potent inhibitor of diacylglycerol acetyl transferase 1 (DGAT1).</p>Fórmula:C22H19ClFN3O3Forma y color:SolidPeso molecular:427.86HMG499
CAS:HMG499 inhibits HMG-CoA reductase (IC50: 0.41μM), reduces statin-induced HMGCR, lowers cholesterol, and lessens atherosclerosis.Fórmula:C33H54O3Pureza:98%Forma y color:SolidPeso molecular:498.78SID 26681509 quarterhydrate
SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).Fórmula:C27H35N5O6SForma y color:SolidPeso molecular:544.16E6201
CAS:E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).Fórmula:C21H27NO6Forma y color:SolidPeso molecular:389.44
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