Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.524 productos)
- Apoptosis(5.793 productos)
- Ciclo celular / Checkpoint(4.452 productos)
- Cromatina / Epigenética(2.242 productos)
- Señalización citoesquelética(1.382 productos)
- Daño al ADN / Reparación del ADN(2.826 productos)
- Endocrinología / Hormonas(3.507 productos)
- Enzima(3.640 productos)
- GPCR / proteína G(8.333 productos)
- Inmunología e inflamación(3.527 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(404 productos)
- Señalización MAPK(1.203 productos)
- Transportador de membrana / canal de iones(2.792 productos)
- Metabolismo(9.449 productos)
- Microbiología / Virología(6.981 productos)
- Neurociencia(9.926 productos)
- Otros inhibidores(37.921 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.400 productos)
- Proteasas / Proteasoma(1.597 productos)
- Células madre y Derivados(830 productos)
- Tirosina quinasa / adaptadores(2.015 productos)
- Ubiquitinación(1.650 productos)
Mostrar 16 subcategorías más
Se han encontrado 66639 productos de "Inhibidores"
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JAK-IN-27
CAS:<p>JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nM</p>Fórmula:C20H21F2N7OPureza:98%Forma y color:SolidPeso molecular:413.42ROCK2-IN-6
CAS:<p>ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].</p>Fórmula:C26H21F2N7OPureza:98%Forma y color:SolidPeso molecular:485.49BET-IN-14
CAS:<p>BET-IN-14 is a pan BET inhibitor with an IC50 of 5.35 nM, demonstrating oral activity and anticancer properties [1].</p>Fórmula:C30H37N7O2Pureza:98%Forma y color:SolidPeso molecular:527.66BTK-IN-25
CAS:<p>BTK-IN-25 (compound 71) is a potent BTK inhibitor, demonstrating an IC50 of 0.77 nM against BTK(C481S) and achieving an IC50 of 1 nM in DOHH2 cells [1].</p>Fórmula:C28H27F2N3O5Pureza:98%Forma y color:SolidPeso molecular:523.53Bi-Mc-VC-PAB-MMAE
CAS:<p>Bi-Mc-VC-PAB-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs), featuring the linker (Fmoc-Val-Cit-PAB) and the potent tubulin inhibitor (</p>Fórmula:C71H104N12O18Forma y color:SolidPeso molecular:1413.66And1-IN-1
CAS:<p>And1-IN-1, also known as compound III, is a potent inhibitor of And1 [1].</p>Fórmula:C15H11BCl2O2Forma y color:SolidPeso molecular:304.96(αR)-Cyclopropaneacetamide-Exatecan
CAS:<p>(αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, serves as a cytotoxic agent that effectively inhibits the proliferation of U87MG</p>Fórmula:C29H28FN3O6Forma y color:SolidPeso molecular:533.55Igermetostat
CAS:<p>Igermetostat, an EZH2 inhibitor, is utilized both in vivo and in vitro for cancer research [1].</p>Fórmula:C32H46N4O4Pureza:98%Forma y color:SolidPeso molecular:550.73ATR-IN-24
CAS:<p>ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].</p>Fórmula:C23H26N6O2Pureza:98%Forma y color:SolidPeso molecular:418.49Ref: TM-T79058
Producto descatalogadoDPP
CAS:<p>DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating</p>Fórmula:C36H40Cl2N2O10PtPureza:98%Forma y color:SolidPeso molecular:926.7I-BET282
CAS:<p>BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1 (example 2, plC50: 6.0 - 7.0).</p>Fórmula:C25H30N4O4Pureza:98%Forma y color:SolidPeso molecular:450.53SARS-CoV-2-IN-68
CAS:<p>SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger</p>Fórmula:C14H12N2OSePureza:98%Forma y color:SolidPeso molecular:303.22Belfosdil
CAS:<p>Belfosdil is a blocker of antihypertensive calcium channel.</p>Fórmula:C27H50O7P2Pureza:98%Forma y color:SolidPeso molecular:548.63ALPK1-IN-3
CAS:<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Fórmula:C20H16F2N4OSPureza:98%Forma y color:SolidPeso molecular:398.43FLT3-IN-19
CAS:<p>FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute</p>Fórmula:C22H26N8OForma y color:SolidPeso molecular:418.49CIAC001
CAS:<p>CIAC001, a pyruvate kinase PKM2 inhibitor, exhibits anti-neuroinflammatory properties.</p>Fórmula:C20H25N3O2Forma y color:SolidPeso molecular:339.43IDO/Tubulin-IN-2
CAS:<p>IDO/Tubulin-IN-2 inhibits TDO/tubulin, effective on U87, HepG2, A549, HCT-116, LO2 cancer cells; IC50 values 0.036-1.04 μM, boosts antitumor action.</p>Fórmula:C48H40N6O10Forma y color:SolidPeso molecular:860.87LFS-1107
CAS:<p>LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].</p>Fórmula:C12H11N5OS2Pureza:98%Forma y color:SolidPeso molecular:305.38RIOK2-IN-2
CAS:<p>RIOK2-IN-2 (8) functions as an inhibitor of RIOK2, exhibiting IC50 values of 3.02 μM in MKN-1 cells and 5.34 μM in MOLT4 cells [1].</p>Fórmula:C27H23F3N6O2Forma y color:SolidPeso molecular:520.51PF-05236216 hydrochloride
CAS:<p>PF-05236216 hydrochloride: Brain-penetrant, potent CK1δ/ε inhibitor affecting mouse circadian rhythms.</p>Fórmula:C18H15FN4OForma y color:SolidPeso molecular:322.34CYY292
CAS:<p>CYY292 is a chemical compound acting as an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, with respective IC50 values of 5.35, 4.6, 28, 28, and 78 nM.</p>Fórmula:C24H28N8OForma y color:SolidPeso molecular:444.53APG-2449
CAS:<p>APG-2449 is an orally active inhibitor targeting ALK, ROS1, and FAK, demonstrating antitumor efficacy in mouse models of non-small cell lung cancer (NSCLC) [1].</p>Fórmula:C33H42ClN5O4SPureza:98%Forma y color:SolidPeso molecular:640.24Ref: TM-T79363
Producto descatalogadoAntibacterial agent 160
CAS:<p>Antibacterial Agent 160 is a potent antibacterial agent that rapidly eradicates bacteria and inhibits the formation of bacterial biofilms.</p>Fórmula:C29H27ClFN3O6Forma y color:SolidPeso molecular:567.99JAK-IN-34
CAS:<p>JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3,</p>Fórmula:C27H26N6OPureza:98%Forma y color:SolidPeso molecular:450.53MDL-811
CAS:<p>MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac),</p>Fórmula:C25H25BrCl2FN3O5S2Pureza:98%Forma y color:SolidPeso molecular:681.42Tibremciclib
CAS:<p>Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].</p>Fórmula:C28H32F2N8Pureza:98%Forma y color:SolidPeso molecular:518.6FAP-IN-2
CAS:<p>FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1].</p>Fórmula:C24H28F2N6O3Forma y color:SolidPeso molecular:486.51S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Fórmula:C25H26F3NO3Pureza:98%Forma y color:SolidPeso molecular:445.47SHP2-IN-14
CAS:<p>SHP2-IN-14 (compound 27) is a potent, orally active allosteric inhibitor of SHP2, displaying strong anti-tumor activity with an IC50 of 7 nM.</p>Fórmula:C22H20Cl2N8OForma y color:SolidPeso molecular:483.35PHI-101
CAS:<p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>Fórmula:C19H19FN4O2SPureza:99.4%Forma y color:SolidPeso molecular:386.44Dimethandrolone Undecanoate
CAS:<p>Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.</p>Fórmula:C31H50O3Pureza:99.65% - >99.99%Forma y color:SolidPeso molecular:470.73Ref: TM-T27176
Producto descatalogadohDHODH-IN-8
<p>hDHODH-IN-8 is a potent human dihydroorotic dehydrogenase (hDHODH) inhibitor (IC50: 16 nM) that exhibits potent antiproliferative effects and has good water solubility, with potential for oncology studies, especially in lymphoma.</p>Fórmula:C21H15F6N3O4Pureza:98%Peso molecular:487.35ALS-I-41
CAS:<p>ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor.</p>Fórmula:C30H38FN3O6SPureza:98%Forma y color:SolidPeso molecular:587.7ROCK-IN-6
CAS:<p>ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1</p>Fórmula:C19H19N5O8SPureza:98%Forma y color:SolidPeso molecular:477.45Ref: TM-T79077
Producto descatalogadoCortivazol
CAS:<p>Cortivazol is an Anti-Inflammatory Drug.</p>Fórmula:C32H38N2O5Pureza:98%Forma y color:SolidPeso molecular:530.65Ref: TM-T25271
Producto descatalogadoBPH-628
CAS:<p>BPH-628 is a bioactive chemical.</p>Fórmula:C20H20O7P2Forma y color:SolidPeso molecular:434.32Ifetroban sodium
CAS:<p>Ifetroban sodium (BMS-180291), oral TXA2/PGH2 antagonist for researching heart, stroke, BP, thrombosis.</p>Fórmula:C25H31N2NaO5Forma y color:SolidPeso molecular:462.522DG026
CAS:<p>DG026 selectively inhibits IRAP, reducing its cross-presentation in dendritic cells without affecting ERAP1.</p>Fórmula:C35H40N3O4PPureza:98%Forma y color:SolidPeso molecular:597.68Ifetroban
CAS:<p>Ifetroban is a potent and selective TxA2/PGH2 receptor antagonist.</p>Fórmula:C25H32N2O5Forma y color:SolidPeso molecular:440.53
