Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.524 productos)
- Apoptosis(5.793 productos)
- Ciclo celular / Checkpoint(4.452 productos)
- Cromatina / Epigenética(2.242 productos)
- Señalización citoesquelética(1.382 productos)
- Daño al ADN / Reparación del ADN(2.826 productos)
- Endocrinología / Hormonas(3.507 productos)
- Enzima(3.640 productos)
- GPCR / proteína G(8.333 productos)
- Inmunología e inflamación(3.527 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(404 productos)
- Señalización MAPK(1.203 productos)
- Transportador de membrana / canal de iones(2.792 productos)
- Metabolismo(9.449 productos)
- Microbiología / Virología(6.981 productos)
- Neurociencia(9.926 productos)
- Otros inhibidores(37.921 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.400 productos)
- Proteasas / Proteasoma(1.597 productos)
- Células madre y Derivados(830 productos)
- Tirosina quinasa / adaptadores(2.015 productos)
- Ubiquitinación(1.650 productos)
Mostrar 16 subcategorías más
Se han encontrado 66639 productos de "Inhibidores"
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Dinalbuphine sebacate
CAS:<p>Dinalbuphine sebacate: long-acting nalbuphine prodrug, μ-opioid partial agonist/antagonist, κ-opioid high-efficacy agonist.</p>Fórmula:C52H68N2O10Forma y color:SolidPeso molecular:881.1Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Fórmula:C18H23N5OSForma y color:SolidPeso molecular:357.47Calphostin B
CAS:<p>Calphostins, PKC inhibitors from Cladosporium fungus, include A, B, C, D, I; C is most potent.</p>Fórmula:C37H34O11Forma y color:SolidPeso molecular:654.662,3-dinor-11β-Prostaglandin F2α
CAS:<p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>Fórmula:C18H30O5Forma y color:SolidPeso molecular:326.43Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Fórmula:C21H27N3SForma y color:SolidPeso molecular:353.52HIF-1α-IN-4
<p>HIF-1α-IN-4 is an inhibitor of HIF-1α with IC50 of 24 nM in HEK293T cells which has potential antitumor effects.</p>Fórmula:C16H12N2O3Forma y color:SolidPeso molecular:280.28GSK065
CAS:<p>GSK065 is a potent inhibitor of kynurenine-3-monooxygenase (KMO).</p>Fórmula:C17H15ClN2O4Forma y color:SolidPeso molecular:346.77AZD-4121
CAS:<p>AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.</p>Fórmula:C36H39F2N3O7SForma y color:SolidPeso molecular:695.77HDAC6/HSP90-IN-2
<p>HDAC6/HSP90-IN-2, a cancer research chemical, inhibits HDAC6 & Hsp90 with IC50s of 105.7 & 61 nM.</p>Fórmula:C19H22N2O5Forma y color:SolidPeso molecular:358.39HDAC10-IN-2
<p>HDAC10-IN-2, a selective HDAC10 inhibitor (IC50=20nM), modulates autophagy in FLT3-ITD+ acute myeloid leukemia.</p>Fórmula:C19H22N2O2Forma y color:SolidPeso molecular:310.39Mcl-1 inhibitor 9
CAS:<p>Mcl-1 Inhibitor 9 (Example 2) is a potent inhibitor of myeloid cell leukemia 1 (Mcl-1), demonstrating anti-tumor activity with an IC50 value of 0.21889 nM.</p>Fórmula:C32H39ClN2O5SForma y color:SolidPeso molecular:599.18YM-355179
CAS:<p>YM-355179 is a novel, selective antagonist of CC chemokine receptor 3 with oral activity.</p>Fórmula:C33H34FN4O7Pureza:98%Forma y color:SolidPeso molecular:617.64BRD-K25923209
CAS:<p>BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.</p>Fórmula:C29H36N4O3Forma y color:SolidPeso molecular:488.62METTL3-IN-3
CAS:<p>METTL3-IN-3 is a polyheterocyclic compound, acts as METTL3 inhibitor .</p>Fórmula:C26H28BrFN6O2Forma y color:SolidPeso molecular:555.44Lentiginosine
CAS:<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Fórmula:C8H15NO2Forma y color:SolidPeso molecular:157.21Neuraminidase-IN-11
<p>Neuraminidase-IN-11 (15e) inhibits H1N1 (IC50: 4.7nM), H5N1 (8.46nM), H5N8 viruses (1.5nM) selectively & potently.</p>Forma y color:SolidMTL-CEBPA
<p>MTL-CEPBA is a small activating RNA that targets C/EBPα upregulation and exhibits anti-inflammatory and anti-cancer effects.</p>Forma y color:SolidHcyb1
<p>Hcyb1 specifically inhibits PDE2A with 0.57 μM IC50, over 250x selective, and has neuroprotective and antidepressant effects.</p>Fórmula:C24H20N4OForma y color:SolidPeso molecular:380.44PROTAC CDK12/13 Degrader-1
<p>PROTAC CDK12/13 Degrader-1 (7f) selectively degrades CDK12/13 at nanomolar potency, targeting breast cancer.</p>Forma y color:SolidTubulin polymerization-IN-35
<p>Tubulin-IN-35 inhibits oxazolylisoindole microtubule formation, targeting VL51 marginal zone lymphoma.</p>Fórmula:C31H35N3O5Forma y color:SolidPeso molecular:529.634α-PDD
CAS:<p>4alpha-PDD activates transient receptor potential vanilloid 4 (TRPV4) channels and is inactive for signaling through PKC.</p>Fórmula:C40H64O8Forma y color:SolidPeso molecular:672.93Henagliflozin
CAS:<p>Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.</p>Fórmula:C22H24ClFO7Forma y color:SolidPeso molecular:454.87TAK-915
CAS:<p>TAK-915: potent, brain-ready PDE2A inhibitor, 0.61 nM IC50, 4100x selectivity over PDE1A.</p>Fórmula:C19H18F4N4O5Pureza:98%Forma y color:SolidPeso molecular:458.36SOS1-IN-10
<p>SOS1-IN-10 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 13 nM).</p>Fórmula:C22H19F5N4OForma y color:SolidPeso molecular:450.4Oxeclosporin
CAS:<p>Oxeclosporin is a hydroxyethyl derivative of serine(8)-cyclosporine; inhibits proliferation and functions of lymphocytes.</p>Fórmula:C64H115N11O14Forma y color:SolidPeso molecular:1262.66RdRP-IN-5
CAS:<p>RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].</p>Fórmula:C23H21N3O5Pureza:98%Forma y color:SolidPeso molecular:419.43AChE/BACE1/GSK3β-IN-1
<p>AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β.</p>Fórmula:C26H27FN2O4Forma y color:SolidPeso molecular:450.5Lepidozin G
<p>Lepidozin G blocks cancer growth (IC50=4.2-5.7μM) and triggers apoptosis in PC-3 cells via mitochondria.</p>Fórmula:C30H48O4Forma y color:SolidPeso molecular:472.7CFT8634
CAS:<p>CFT8634 degrades BRD9, for synovial sarcoma and SMARCB1 tumor research, from patent WO2021178920A1.</p>Fórmula:C37H45F3N6O5Forma y color:SolidPeso molecular:710.79WQ3810
CAS:<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Fórmula:C22H22F3N5O3Pureza:98%Forma y color:SolidPeso molecular:461.44Vanin-1-IN-3
<p>Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC 50 of 0.038 μM [1].</p>Fórmula:C17H22F3NO5Forma y color:SolidPeso molecular:377.36CRS-3123
CAS:<p>CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.</p>Fórmula:C19H19Br2N3O2SPureza:98%Forma y color:SolidPeso molecular:513.25MAO A/HDAC-IN-1
<p>MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.</p>Fórmula:C21H24ClN3O3Forma y color:SolidPeso molecular:401.89Serlopitant
CAS:<p>Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.</p>Fórmula:C29H28F7NO2Forma y color:SolidPeso molecular:555.53KF 20274
CAS:<p>KF 20274 is an adenosine A1 antagonist; purinergic receptor antagonist.</p>Fórmula:C21H29N5OForma y color:SolidPeso molecular:367.49Topoisomerase I inhibitor 8
CAS:<p>Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.</p>Fórmula:C24H21FN2O4Forma y color:SolidPeso molecular:420.43CXCR4 modulator-1
CAS:<p>CXCR4 modulator-1 (ZINC72372983) is potent (EC50=100nM) with uses in anti-inflammatory, anticancer, and anti-HIV research.</p>Fórmula:C23H27N5O2Forma y color:SolidPeso molecular:405.49Lp-PLA2-IN-6
CAS:<p>Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.</p>Fórmula:C25H21F5N4O3Forma y color:SolidPeso molecular:520.45PARP10/15-IN-1
<p>PARP10/15-IN-1 (compound 8l) is a dual PARP10 and PARP15 inhibitor with IC50s of 160 nM and 370 nM, respectively. It can be used in cancer research[1].</p>Fórmula:C13H10N2O3SForma y color:SolidPeso molecular:274.3Antioxidant agent-8
<p>Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.</p>Fórmula:C13H12O5Forma y color:SolidPeso molecular:248.23SB-612111
CAS:<p>SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.</p>Fórmula:C24H29Cl2NOForma y color:SolidPeso molecular:418.40RET-IN-14
CAS:<p>RET-IN-14 inhibits RET (IC50: <0.51-9.3 nM) & BTK (C481S) (IC50: 9.2-15 nM), promising for tumor research.</p>Fórmula:C24H23FN8O4Forma y color:SolidPeso molecular:506.49MRTX849 ethoxypropanoic acid
CAS:<p>MRTX849 is a KRAS G12C ligand and PROTAC linker for creating potent LC-2, degrading KRAS G12C with DC50 of 0.25-0.76 μM.</p>Fórmula:C37H43ClFN7O5Forma y color:SolidPeso molecular:720.24BTK-IN-6
<p>BTK-IN-6, a potent BTK inhibitor, may treat immune, cardiac, cancer, viral, inflammatory, metabolic, and neurological disorders.</p>Fórmula:C23H22FN5O3Forma y color:SolidPeso molecular:435.45TrxR-IN-2
<p>TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.</p>Fórmula:C22H22N4O4Forma y color:SolidPeso molecular:406.43D4R antagonis-2
<p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>Fórmula:C21H23ClF2N2O2Forma y color:SolidPeso molecular:408.87PI3K-IN-35
CAS:<p>PI3K-IN-35 (6l) selectively inhibits PI3K-α, β, δ (IC50: 13.98, 7.22, 10.94 μM), blocks G2/M phase, induces apoptosis, and is useful in leukemia research.</p>Fórmula:C25H23N7O2Forma y color:SolidPeso molecular:453.5Dinordrin I diacetate
CAS:<p>Dinordrin I diacetate is an implantation inhibitor and hormone.</p>Fórmula:C25H32O4Pureza:98%Forma y color:SolidPeso molecular:396.52CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Fórmula:C26H26N2O6SForma y color:SolidPeso molecular:494.56RO5101576
CAS:<p>RO5101576 is a potent antagonist of LTB4 receptor.</p>Fórmula:C36H38O8SPureza:98%Forma y color:SolidPeso molecular:630.75trans-RdRP-IN-5
<p>Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.</p>Fórmula:C23H21N3O5Forma y color:SolidPeso molecular:419.43NTPDase-IN-2
CAS:<p>NTPDase-IN-2 inhibits h-NTPDase-2/-8 (IC50: 0.04, 2.27 µM), non-competitive for h-NTPDase-1/-2 (Km: 74 µM); useful in cancer, immune, bacterial research.</p>Fórmula:C24H20FN3OS2Forma y color:SolidPeso molecular:449.56AQX-435
CAS:<p>AQX-435 activates SHIP1, inhibits PI3K in BCR signaling, induces apoptosis in B cells, and slows lymphoma growth.</p>Fórmula:C27H34N2O4Forma y color:SolidPeso molecular:450.57OSI-7904L free acid
CAS:<p>OSI-7904L is a folate-based thymidylate synthase inhibitor. It also has antimalarial and antitumor properties.</p>Fórmula:C27H24N4O6Pureza:98%Forma y color:SolidPeso molecular:500.5L-97-1
CAS:<p>L-97-1 is an antagonist of the adenosine A1 receptor.</p>Fórmula:C29H38N6O3Pureza:98%Forma y color:SolidPeso molecular:518.65Pyrromycin
CAS:<p>Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.</p>Fórmula:C30H35NO11Forma y color:SolidPeso molecular:585.60T-3861174
CAS:<p>T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation.</p>Fórmula:C26H25FN6O2Forma y color:SolidPeso molecular:472.51Dihydrokainic acid
CAS:<p>EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake</p>Fórmula:C10H17NO4Pureza:98%Forma y color:SolidPeso molecular:215.25PF-06273340
CAS:<p>PF-06273340 是一种口服具有活力的、具有选择性的外周限制性Trk 泛抑制剂。</p>Fórmula:C23H22ClN7O3Pureza:98% - 98.00%Forma y color:SolidPeso molecular:479.92Vulolisib
CAS:<p>Vulolisib inhibits PI3K (α: IC50 0.2nM, β: 168nM, γ: 90nM, δ: 49nM), taken orally with anti-cancer properties.</p>Fórmula:C18H19F2N5O3SForma y color:SolidPeso molecular:423.44BI 224436
CAS:<p>BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.</p>Fórmula:C27H26N2O4Forma y color:SolidPeso molecular:442.51MT-134
<p>MT-134 is a SkMII -specific inhibitor and has excellent exposure in muscles.</p>Fórmula:C19H16N4O3Forma y color:SolidPeso molecular:348.36RMG8-8
<p>RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).</p>Fórmula:C41H78N8O5Forma y color:SolidPeso molecular:763.11Z-FY-CHO
CAS:<p>Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.</p>Fórmula:C26H26N2O5Pureza:95.88%Forma y color:SolidPeso molecular:446.5PI3kδ inhibitor 1
CAS:<p>PI3kδ inhibitor 1 is a selective inhibitor of PI3Kδ (IC50 of 3.8 nM).</p>Fórmula:C28H33FN6O2Pureza:98%Forma y color:SolidPeso molecular:504.60GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Fórmula:C17H16ClN3O4Pureza:98%Forma y color:SolidPeso molecular:361.78Anti-Influenza agent 3
<p>Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).</p>Fórmula:C16H22ClNOSForma y color:SolidPeso molecular:311.87Elocalcitol
CAS:<p>Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.</p>Fórmula:C29H43FO2Forma y color:SolidPeso molecular:442.65Topo I-IN-1
<p>Topo I-IN-1 (14d) is a powerful Topo I inhibitor with antitumor effects and DNA intercalation, inducing apoptosis.</p>Fórmula:C20H14BrN3O2Forma y color:SolidPeso molecular:408.25Gabaculine HCl
CAS:<p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>Fórmula:C7H10ClNO2Forma y color:SolidPeso molecular:175.61QW24
CAS:<p>QW24 down-regulates BMI-1, exhibits potent antitumour effects and is used as an effective therapeutic agent in the treatment of clinical colorectal cancer.</p>Fórmula:C27H28N2O4Forma y color:SolidPeso molecular:444.52Mibefradil dihydrochloride hydrate
CAS:<p>Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.</p>Fórmula:C29H42Cl2FN3O4Forma y color:SolidPeso molecular:586.57Akt/NF-κB/JNK-IN-1
<p>Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide</p>Fórmula:C22H22N2O6Forma y color:SolidPeso molecular:410.42Equisetin
CAS:<p>Equisetin: a QSI from Fusarium equiseti, curbs P. aeruginosa virulence, fights Gram-positive bacteria & HIV-1 integrase; not antibacterial to Gram-negative.</p>Fórmula:C22H31NO4Pureza:98%Forma y color:SolidPeso molecular:373.49CDK7-IN-17
CAS:<p>CDK7-IN-17, a pyrimidine-based CDK7 inhibitor, shows promise for various cancers, especially with abnormal transcription.</p>Fórmula:C24H26F3N6OPForma y color:SolidPeso molecular:502.47Steroid sulfatase-IN-4
<p>Steroid sulfatase-IN-4 irreversibly inhibits human STS with a 25 nM IC50, useful for endometriosis research.</p>Fórmula:C19H17ClN2O5SForma y color:SolidPeso molecular:420.87Aeruginosin 98-B
CAS:<p>Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.</p>Fórmula:C29H46N6O9SForma y color:SolidPeso molecular:654.78HBV-IN-19 TFA
CAS:<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Fórmula:C26H31F3N2O8Forma y color:SolidPeso molecular:556.53JH295 hydrate
<p>JH295 hydrate: potent, irreversible Nek2 inhibitor (IC50 = 770 nM), selective, doesn't target Cdk1, Aurora B or Plk1.</p>Fórmula:C18H18N4O3Forma y color:SolidPeso molecular:338.36D18
CAS:<p>D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.</p>Fórmula:C21H28N6Forma y color:SolidPeso molecular:364.49PRMT5-IN-18
CAS:<p>PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.</p>Fórmula:C32H42N4O4Forma y color:SolidPeso molecular:546.70GPR84 antagonist 1
<p>GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.</p>Fórmula:C26H22N4O2Forma y color:SolidPeso molecular:422.48PF-06462894
CAS:PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Fórmula:C18H23N3O3Pureza:98%Forma y color:SolidPeso molecular:329.39MB-7133
CAS:<p>MB-7133 is an inhibitor of DNA synthesis.</p>Fórmula:C17H21N4O8PPureza:98%Forma y color:SolidPeso molecular:440.34OP-5244
CAS:<p>OP-5244 has comparable potency to bisphosphonic acid series and targets CD73.</p>Fórmula:C19H29ClN5O9PPureza:98%Forma y color:SolidPeso molecular:537.89COTC
CAS:<p>COTC is an anticancer bacterial metabolite; inhibits glyoxalase with GSH, halts HeLa cell growth, and fights tumor in Ehrlich murine model.</p>Fórmula:C11H14O6Forma y color:SolidPeso molecular:242.23VEGFR-2/DHFR-IN-2
<p>VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.</p>Fórmula:C21H21NO4Forma y color:SolidPeso molecular:351.4Cilobamine mesylate
CAS:<p>Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.</p>Fórmula:C18H27Cl2NO4SForma y color:SolidPeso molecular:424.38Kolavenic acid analog
CAS:<p>KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.</p>Fórmula:C25H38O4Forma y color:SolidPeso molecular:402.57VEGFR-2-IN-26
CAS:<p>VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.</p>Fórmula:C24H19F3N6O2Forma y color:SolidPeso molecular:480.44CGS 22652
CAS:<p>CGS 22652 has thromboxane receptor antagonism combined with thromboxane synthase inhibition.</p>Fórmula:C22H29ClN2O4SForma y color:SolidPeso molecular:452.99HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Fórmula:C25H21N5OSForma y color:SolidPeso molecular:439.53PTP1B-IN-19
<p>PTP1B-IN-19, a benzimidazole, selectively inhibits protein tyrosine phosphatase 1B with a Ki of 23.3 μM, potential for type 2 diabetes research.</p>Fórmula:C26H19N3O4SForma y color:SolidPeso molecular:469.51Gimatecan
CAS:Gimatecan (STI481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.Fórmula:C25H25N3O5Pureza:98.47%Forma y color:SolidPeso molecular:447.48(rel)-Myrislignan
CAS:<p>(rel)-Myrislignan, a lignan compound with a relative configuration, has been isolated from Myristica fragrans Houtt.</p>Fórmula:C21H26O6Pureza:98%Forma y color:SolidPeso molecular:374.43844-TFM
<p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>Fórmula:C24H25F3N4O2Forma y color:SolidPeso molecular:458.48Antitumor agent-65
CAS:<p>Antitumor agent-65 (Compound 5) is an analogue/derivative of (-)-cleistenolide. Antitumor agent-65 has potential in cancer research.</p>Fórmula:C18H17NO10Forma y color:SolidPeso molecular:407.33LSD1-IN-17
<p>LSD1-IN-17, a potent LSD1/CoREST/MAO inhibitor, IC50: 0.005/0.028/0.820 μM; hinders LNCaP prostate cancer cell growth, IC50: 17.2 μM.</p>Fórmula:C20H18N2OSForma y color:SolidPeso molecular:334.43MS8511
CAS:<p>MS8511: Selective, irreversible G9a/GLP inhibitor. IC50: 100 nM (G9a), 140 nM (GLP). Lowers H3K9me2, anti-proliferative. Useful in cancer/AD/PWS research.</p>Fórmula:C28H41N5O3Forma y color:SolidPeso molecular:495.66MA242
CAS:<p>MA242 is a nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy and dual inhibitor of murine double minute 2 (MDM2).</p>Fórmula:C26H21ClF3N3O5SPureza:98%Forma y color:SolidPeso molecular:579.98Antitumor agent-43
<p>Antitumor agent-43 (Compound 4B) is a potent antitumor agent that induces cell cycle arrest at G2/M phase.</p>Fórmula:C16H8N2O3Forma y color:SolidPeso molecular:276.25G-479
CAS:<p>G-479, a potent MEK inhibitor and improved analogue of GDC-0623, has distributed polarity enhancing bioactivity.</p>Fórmula:C16H15FIN5O4Forma y color:SolidPeso molecular:487.22Coleon-U-quinone
CAS:<p>Coleon-U-quinone, a P-gp inhibitor, reduces cancer cell viability and enhances Doxorubicin sensitivity in resistant cells.</p>Fórmula:C20H24O5Forma y color:SolidPeso molecular:344.4GSK789
CAS:<p>GSK789 is a selective inhibitor of the first bromodomains (BD1) of the bromo and extra terminal domain (BET) proteins.</p>Fórmula:C26H33N5O3Forma y color:SolidPeso molecular:463.57PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Fórmula:C18H20ClN3OSForma y color:SolidPeso molecular:361.89BDZ-h
CAS:<p>BDZ-h inhibits both closed/open states of all 4 homomeric & 2 GluA2R-complex AMPA receptors.</p>Fórmula:C21H21N5O3SForma y color:SolidPeso molecular:423.49COX-2/PI3K-IN-2
<p>COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).</p>Fórmula:C16H17N5O2Forma y color:SolidPeso molecular:311.34PPARγ agonist 1
<p>PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects.</p>Fórmula:C34H39NO3Forma y color:SolidPeso molecular:509.68CEP-14083
CAS:<p>CEP-14083: potent ALK inhibitor, effective in NPM/ALK T-cell lymphoma, binds ATP site; IC50=11 nmol/L, also inhibits insulin receptor, preclinical efficacy.</p>Fórmula:C31H30N6O2Forma y color:SolidPeso molecular:518.61Antileishmanial agent-4
<p>Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].</p>Fórmula:C17H18N4O4Forma y color:SolidPeso molecular:342.35Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Fórmula:C24H33BrN2O2Forma y color:SolidPeso molecular:461.44GLP-1R agonist 8
CAS:<p>GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).</p>Fórmula:C33H32N4O5Forma y color:SolidPeso molecular:564.63SP-471
<p>SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.</p>Fórmula:C33H26BrN5Forma y color:SolidPeso molecular:572.5Tzc 5665
CAS:<p>Tzc 5665 is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory action.</p>Fórmula:C31H38ClN5O7Forma y color:SolidPeso molecular:628.12Mu opioid receptor antagonist 4
<p>Compound 31: Potent, selective MOR antagonist; crosses blood-brain barrier; Ki & EC50: 0.38 nM; useful for OUD research.</p>Fórmula:C25H28N2O4SForma y color:SolidPeso molecular:452.57Sdz 210-096
CAS:<p>Sdz 210-096: a 14 beta-benzyl morphinan, mu/kappa opiate receptor antagonist, stimulates LH secretion in rats.</p>Fórmula:C27H31NO2Forma y color:SolidPeso molecular:401.54Aniline-MPB-amino-C3-PBD
CAS:<p>Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent.</p>Fórmula:C42H46N8O6Pureza:98%Forma y color:SolidPeso molecular:758.86Rafutrombopag
CAS:<p>Rafutrombopag is a thrombopoietin (TPO) agonist.</p>Fórmula:C25H22N4O5Forma y color:SolidPeso molecular:458.47Agarospirol
CAS:<p>Agarospirol has partial anti-inflammatory activity.</p>Fórmula:C15H26OPureza:98%Forma y color:SolidPeso molecular:222.37TY 11223
CAS:<p>TY 11223: stable homoisocarbacyclin analog, potently inhibits platelet aggregation with lasting effect and selective activity.</p>Fórmula:C24H34O5Forma y color:SolidPeso molecular:402.52Lipoxin A5
CAS:<p>LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.</p>Fórmula:C20H30O5Forma y color:SolidPeso molecular:350.45GNE-616
CAS:<p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>Fórmula:C24H23F4N5O3SPureza:98%Forma y color:SolidPeso molecular:537.53MALT1-IN-11
CAS:<p>MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.</p>Fórmula:C20H16F4N8OForma y color:SolidPeso molecular:460.39CV 5975
CAS:<p>CV 5975 is a nonsulfhydryl ACE inhibitor that was investigated for use in hypertension and heart failure.</p>Fórmula:C22H31N3O5SForma y color:SolidPeso molecular:449.56MK2-IN-4
CAS:<p>MK2-IN-4 is a MAPKAPK2 (MK2) inhibitor (IC50: 45 nM). MK2-IN-4 can be used in cancer, inflammation and immunology studies.</p>Fórmula:C25H24N4O2Forma y color:SolidPeso molecular:412.48MRS2279
CAS:<p>Selective, high affinity competitive antagonist of the P2Y1 receptor</p>Fórmula:C13H18ClN5O8P2Pureza:98%Forma y color:SolidPeso molecular:469.71Zurletrectinib
CAS:<p>Zurletrectinib is a tyrosine kinase inhibitor with potential as an antineoplastic agent.</p>Fórmula:C19H19F2N7O2Forma y color:SolidPeso molecular:415.4Novokinin
CAS:<p>Angiotensin AT2 receptor agonist</p>Fórmula:C39H61N11O7Pureza:98%Forma y color:SolidPeso molecular:795.97MCTR1
CAS:<p>MCTR1, a pro-resolving mediator derived from DHA, promotes tissue repair and reduces inflammation by enhancing phagocytosis and decreasing eicosanoids.</p>Fórmula:C32H47N3O9SForma y color:SolidPeso molecular:649.8CDK7/12-IN-1
CAS:<p>CDK7/12-IN-1 is a selective CDK7 (IC50: 3 nM) and CDK12 (IC50: 277 nM) inhibitor, effective against tumor growth.</p>Fórmula:C25H34N8OForma y color:SolidPeso molecular:462.59R-96544 hydrochloride
CAS:<p>5-HT2 receptor antagonist</p>Fórmula:C22H29NO3Pureza:98%Forma y color:SolidPeso molecular:355.47NSC 828467
<p>NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).</p>Fórmula:C21H19N9O2SForma y color:SolidPeso molecular:461.5PI3Kα-IN-8
<p>PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM).</p>Fórmula:C26H27BrN4O2Forma y color:SolidPeso molecular:507.42EFdA-TP tetrasodium
CAS:<p>EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.</p>Fórmula:C12H11FN5Na4O12P3Pureza:98%Forma y color:SolidPeso molecular:621.12Antitrypanosomal agent 6
<p>Compound 18a: potent vs. T. brucei (IC50: 0.47 μM), >2x efficacy compared to Nifurtimox, good ADME, binds AT-rich DNA.</p>Fórmula:C22H29Cl2N5OForma y color:SolidPeso molecular:450.4Nenocorilant
CAS:<p>Nenocorilant (Relacorilant) is an orally active glucocorticoid receptor (GR) antagonist (Ki: 0.15 nM). Nenocorilant can be used to study tumours.</p>Fórmula:C26H21F4N7O3SForma y color:SolidPeso molecular:587.55GSK3739936
CAS:<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Fórmula:C34H43FN2O4Forma y color:SolidPeso molecular:562.71MK-1220
CAS:<p>MK-1220 is a novel Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure.</p>Fórmula:C40H53N5O9SForma y color:SolidPeso molecular:779.94RAD51-IN-7
CAS:<p>RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)</p>Fórmula:C25H31N5O4S2Forma y color:SolidPeso molecular:529.67CM-414
CAS:<p>CM-414: HDAC/PDE5 inhibitor, targeting Alzheimer’s, IC50s: PDE5 (60 nM), HDAC1/2/3/6. Reduces Aβ, pTau in mice, boosts cognition.</p>Fórmula:C23H29N5O4Pureza:98%Forma y color:SolidPeso molecular:439.51Anticancer agent 35
<p>Compound 10, a sulfonylurea, inhibits A549, A431, PACA2 cells with IC50s: 18.1, 4.0, 18.9 μg/mL.</p>Fórmula:C15H13N3O3S3Forma y color:SolidPeso molecular:379.48MSK-195
CAS:<p>MSK-195 is an effective TRPV1 agonist.</p>Fórmula:C28H40N2O5Pureza:98%Forma y color:SolidPeso molecular:484.63Protease-Activated Receptor-1 antagonist 3
<p>PAR-1 antagonist 3: potent (IC50: 7 nM), binds hERG K+ channels (IC50: 9 μM).</p>Fórmula:C30H34N4O3Forma y color:SolidPeso molecular:498.62Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Fórmula:C35H23N5O5Forma y color:SolidPeso molecular:593.59DENV-IN-6
CAS:<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Fórmula:C23H26ClFN4OSForma y color:SolidPeso molecular:461(rel)-AR234960
CAS:(rel)-AR234960 is an active relative configuration of AR234960. AR234960 is a non-peptide agonist of MAS.Fórmula:C27H30FN5O5SForma y color:SolidPeso molecular:555.63AD013
<p>AD013 is a selective ACE inhibitor and NEP inhibitor with potential anti-hypertensive and cardioprotective benefits.</p>Fórmula:C24H28N2O5Forma y color:SolidPeso molecular:424.49NRX-2663
CAS:<p>NRX-2663 boosts β-catenin binding to E3 ligase SCFβ-TrCP (Kd: 54.8 nM, EC50: 22.9 nM).</p>Fórmula:C20H13F3N2O5Forma y color:SolidPeso molecular:418.32FK-3657
CAS:<p>FK-3657 is a non-peptide antagonist of bradykinin (BK)-B2 receptor.</p>Fórmula:C30H27Cl2N5O4Forma y color:SolidPeso molecular:592.4711-trans Leukotriene E4
CAS:<p>Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.</p>Fórmula:C23H37NO5SForma y color:SolidPeso molecular:439.61CDK4/6-IN-10
<p>CDK4/6-IN-10: Oral CDK4 (IC50: 22 nM) & CDK6 (IC50: 10 nM) inhibitor with anti-cancer potential for MM research.</p>Forma y color:SolidcSPM
<p>cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.</p>Fórmula:C27H57N7Forma y color:SolidPeso molecular:479.79CDK1-IN-3
<p>CDK1-IN-3 is a selective inhibitor targeting CDK1 (36.8 nM), CDK2 (305.17 nM), CDK5 (369.37 nM); used in cancer research.</p>Fórmula:C28H25ClF3N5O2Forma y color:SolidPeso molecular:555.98ABT 491 Hydrochloride
CAS:<p>ABT-491 hydrochloride is an active platelet activator receptor (PAF-R) antagonist with good selectivity and oral administration.</p>Fórmula:C28H23ClFN5O2Forma y color:SolidPeso molecular:515.97Mimocine
CAS:<p>Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).</p>Fórmula:C15H14N2O5Forma y color:SolidPeso molecular:302.28Methyl Streptonigrin
CAS:<p>Methyl Streptonigrin is an ABCG2 transporter function inhibitor.</p>Fórmula:C26H24N4O8Pureza:98%Forma y color:SolidPeso molecular:520.49HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Fórmula:C21H32ClN7O3Forma y color:SolidPeso molecular:465.98SLN124
<p>SLN124, a GalNAc-siRNA targeting TMPRSS6, may normalize iron balance by restoring ferroregulation.</p>Forma y color:SolidOrg-6906
CAS:<p>DCB-3503, a tylophorine analog, may treat cancer and suppress immunity by blocking protein synthesis and modulating HSC70's ATPase activity.</p>Fórmula:C13H16ClNPureza:98%Forma y color:SolidPeso molecular:221.73CGC 11144
CAS:<p>CGC 11144 is a Polyamine analogue inhibit tumor growth in vitro and in vivo.</p>Fórmula:C40H100Cl10N10Forma y color:SolidPeso molecular:1075.82CHK1-IN-2
CAS:<p>CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).</p>Fórmula:C20H22N4OSPureza:98%Forma y color:SolidPeso molecular:366.48RORγt/DHODH-IN-1
CAS:<p>RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significant</p>Fórmula:C24H26ClF6N3O3SForma y color:SolidPeso molecular:585.99MDL-100173
CAS:<p>MDL-100173 is a dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitor.</p>Fórmula:C24H26N2O4SForma y color:SolidPeso molecular:438.54ML-SI1
CAS:<p>ML-SI1, a racemic mixture of diastereoisomers, is a TRPML inhibitor and acts on TRPML1 (IC50: 15 μM).</p>Fórmula:C23H26Cl2N2O3Forma y color:SolidPeso molecular:449.37AG-7404
CAS:<p>AG-7404: strong protease inhibitor, fights poliovirus, EC50 0.080-0.674 μM, effective on V-073-resistant strains.</p>Fórmula:C26H29N5O7Forma y color:SolidPeso molecular:523.54GNE-2256
CAS:<p>GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has</p>Fórmula:C24H27FN6O4Forma y color:SolidPeso molecular:482.51HPK1-IN-14
CAS:<p>HPK1-IN-14 is a potent inhibitor of HPK1. HPK1-IN-14 has potential for the study of HPK1-related diseases.</p>Fórmula:C24H23FN6O2Forma y color:SolidPeso molecular:446.48RTIOX-372
CAS:<p>RTIOX-372 is a potent and selective orexin-1 receptor antagonist.</p>Fórmula:C30H39N5O3Forma y color:SolidPeso molecular:517.66LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Fórmula:C21H11D7F3N5O3Forma y color:SolidPeso molecular:452.44(E)-10-Hydroxynortriptyline maleate
CAS:<p>(E)-10-Hydroxy Nortriptyline maleate, a derivative of antidepressant Nortriptyline, eases depression symptoms.</p>Fórmula:C23H25NO5Pureza:98%Forma y color:SolidPeso molecular:395.455Dopamine D3 receptor antagonist-2
<p>Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.</p>Fórmula:C23H27Cl2N3O3Forma y color:SolidPeso molecular:464.38PD-149163
CAS:<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Fórmula:C42H71N9O6Forma y color:SolidPeso molecular:798.07Tubulin inhibitor 14
<p>Tubulin inhibitor 14 blocks NQO2 and microtubule formation, disrupts blood vessels, and may target tumors; IC50 of 1.0 μM.</p>Fórmula:C15H9F2NOForma y color:SolidPeso molecular:257.23MtTMPK-IN-5
<p>MtTMPK-IN-5 inhibits Mtb TMPK with IC50 of 34 μM and fights tuberculosis with MIC of 12.5 μM, aiding TB research.</p>Fórmula:C21H23N5O2Forma y color:SolidPeso molecular:377.44AL 6598
CAS:<p>AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.</p>Fórmula:C23H39ClO5Forma y color:SolidPeso molecular:431.018-iso Prostaglandin F3α
CAS:<p>8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA.</p>Fórmula:C20H32O5Forma y color:SolidPeso molecular:352.47Carbonic anhydrase inhibitor 5
<p>Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.</p>Fórmula:C24H20ClN3O3SForma y color:SolidPeso molecular:465.95PARP7-IN-12
CAS:<p>PARP7-IN-12, a potent inhibitor targeting PARP7, exhibits an IC50 of 7.836 nM. This compound is applicable in cancer research.</p>Fórmula:C23H27ClF3N5O5Forma y color:SolidPeso molecular:545.94CP-481715
CAS:<p>CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.</p>Fórmula:C26H31FN4O4Forma y color:SolidPeso molecular:482.55LY3130481
CAS:<p>LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.</p>Fórmula:C19H18N4O3SForma y color:SolidPeso molecular:382.44Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Fórmula:C29H31ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:590.04Topoisomerase II inhibitor 5
<p>Topoisomerase II inhibitor 5 (Compound E24) is a DNAtopoisomerase II inhibitor with anticancer effects.</p>Fórmula:C26H27N5O4Forma y color:SolidPeso molecular:473.52Anticancer agent 69
<p>Anticancer agent 69 targets PC3 cells (IC50=26 nM), raises ROS, lowers EGFR, and induces apoptosis.</p>Fórmula:C19H26N8SForma y color:SolidPeso molecular:398.53Thiomuscimol hydrobromide
CAS:<p>Thiomuscimol hydrobromide is an agonist of GABAA receptor.</p>Fórmula:C4H6N2OSPureza:98%Forma y color:SolidPeso molecular:130.17Methysergide maleate
CAS:<p>Methysergide prevents migraines/cluster headaches; treats serotonin syndrome, carcinoid-induced diarrhea; risk of fibrosis limits use.</p>Fórmula:C25H31N3O6Pureza:98%Forma y color:White To Off-WhitePeso molecular:469.54LRRK2-IN-2
CAS:<p>LRRK2-IN-2: selective, potent LRRK2 inhibitor, IC50 of 0.6 nM, oral, crosses blood-brain barrier, for Parkinson's research.</p>Fórmula:C23H23Cl2F3N6O2Forma y color:SolidPeso molecular:543.37L-690330 hydrate
<p>L-690330 hydrate inhibits IMPase; Ki: 0.30 μM (human), 0.42 μM (bovine cortex); 0.27 μM (recom. human), 0.19 μM (bovine).</p>Fórmula:C8H14O9P2Forma y color:SolidPeso molecular:316.14AChE/BChE-IN-3 hydrochloride
<p>AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.</p>Fórmula:C15H25ClN2O3Forma y color:SolidPeso molecular:316.82Rimegepant sulfate hydrate
CAS:<p>Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.</p>Fórmula:C56H64F4N12O13SForma y color:SolidPeso molecular:1221.2526(S)-3-Hydroxy Midostaurin
CAS:<p>(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).</p>Fórmula:C35H30N4O5Pureza:98%Forma y color:SolidPeso molecular:586.64GID4 Ligand 1
<p>GID4 Ligand 1: cell-permeable, selective binder, IC50 5.4 μM, Kd 5.6 μM, binds in cells with EC50 558 nM, useful for PROTAC synthesis.</p>Fórmula:C28H34N4O5SForma y color:SolidPeso molecular:538.66NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Fórmula:C20H25ClN4O3SPureza:98%Forma y color:SolidPeso molecular:436.96LX2761
CAS:<p>LX2761 is a stable inhibitor for SGLT1/2 with IC50s of 2.2/2.7 nM; it targets SGLT1 in the GI tract.</p>Fórmula:C32H47N3O6SPureza:98%Forma y color:SolidPeso molecular:601.80Pexacerfont
CAS:<p>Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).</p>Fórmula:C18H24N6OPureza:99.77%Forma y color:SolidPeso molecular:340.42FGFR4-IN-6
<p>FGFR4-IN-6: covalent, reversible FGFR4 blocker, 5.4 nM IC50, good oral bioavailability, reduces Hep3B2.1-7 tumors in mice, low toxicity.</p>Fórmula:C31H33N7O4Forma y color:SolidPeso molecular:567.64A4B17
<p>A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.</p>Fórmula:C14H7F4NSForma y color:SolidPeso molecular:297.27SSR-241586
CAS:<p>SSR-241586: Neurokinin antagonist, treats depression, schizophrenia, urinary issues, emesis, IBS.</p>Fórmula:C32H42Cl2N4O3Pureza:98%Forma y color:SolidPeso molecular:601.61IRAK4-IN-14
CAS:<p>IRAK4-IN-14 is a selective, potent, orally active IRAK4 inhibitor (IC50: 0.003 μM) with favorable PK parameters in rats and mice. effect.</p>Fórmula:C25H28FN9OForma y color:SolidPeso molecular:489.55α-Glucosidase-IN-14
<p>α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).</p>Fórmula:C24H27N5O4S2Forma y color:SolidPeso molecular:513.63Anticancer agent 80
<p>Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).</p>Fórmula:C19H12BrNO5Forma y color:SolidPeso molecular:414.21
