Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.524 productos)
- Apoptosis(5.793 productos)
- Ciclo celular / Checkpoint(4.452 productos)
- Cromatina / Epigenética(2.242 productos)
- Señalización citoesquelética(1.382 productos)
- Daño al ADN / Reparación del ADN(2.826 productos)
- Endocrinología / Hormonas(3.507 productos)
- Enzima(3.640 productos)
- GPCR / proteína G(8.333 productos)
- Inmunología e inflamación(3.527 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(404 productos)
- Señalización MAPK(1.203 productos)
- Transportador de membrana / canal de iones(2.792 productos)
- Metabolismo(9.449 productos)
- Microbiología / Virología(6.981 productos)
- Neurociencia(9.926 productos)
- Otros inhibidores(37.921 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.400 productos)
- Proteasas / Proteasoma(1.597 productos)
- Células madre y Derivados(830 productos)
- Tirosina quinasa / adaptadores(2.015 productos)
- Ubiquitinación(1.650 productos)
Mostrar 16 subcategorías más
Se han encontrado 66639 productos de "Inhibidores"
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ETP-47037
CAS:<p>ETP-47037: strong PI3Kα inhibitor (IC50: 0.99 nM), also targets PI3Kβ, δ, γ; may protect telomeres.</p>Fórmula:C20H27N9O3SForma y color:SolidPeso molecular:473.555α-reductase-IN-1
CAS:<p>5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase.</p>Fórmula:C31H37NO5Pureza:98%Forma y color:SolidPeso molecular:503.63PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Fórmula:C18H20ClN3OSForma y color:SolidPeso molecular:361.89HDAC-IN-34
<p>HDAC-IN-34 inhibits HDAC1 (IC50: 0.022 μM) & HDAC6 (IC50: 0.45 μM), binds DNA causing damage, and halts HCT-116 cell growth (IC50: 1.41 μM).</p>Fórmula:C24H26N6O3Forma y color:SolidPeso molecular:446.5Carbonic anhydrase inhibitor 4
<p>CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.</p>Fórmula:C21H18N2O4SForma y color:SolidPeso molecular:394.44BPTF-IN-BZ1
<p>BPTF-IN-BZ1 is a BPTF inhibitor that possesses a high potency with a Kd of 6.3 nM.</p>Fórmula:C13H15ClN4OForma y color:SolidPeso molecular:278.74ATR-IN-7
CAS:<p>ATR-IN-7 is a potent inhibitor of ATR.</p>Fórmula:C21H22FN7OForma y color:SolidPeso molecular:407.44Hit 1
<p>Hit 1 is an activator of insulin-degrading enzymes (IDE) (EC50: 5.5 μM) and reduces glucose-stimulated insulin secretion.</p>Fórmula:C22H24N4O3S2Forma y color:SolidPeso molecular:456.58Wikstrol A
CAS:<p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>Fórmula:C30H22O10Forma y color:SolidPeso molecular:542.49F 14679
CAS:<p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>Fórmula:C21H25ClF2N4OPureza:99.09%Forma y color:SolidPeso molecular:422.9EGFR-IN-23
CAS:<p>EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.</p>Fórmula:C36H44BrN10O3PForma y color:SolidPeso molecular:775.68CaMKIIα-IN-1
<p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>Fórmula:C14H11ClO4Forma y color:SolidPeso molecular:278.69Gougerotin
CAS:<p>Gougerotin is an inhibitor of protein synthesis.</p>Fórmula:C16H25N7O8Forma y color:SolidPeso molecular:443.41Casuarinin
CAS:<p>Casuarinin, an ellagitannin found in pomegranates and certain Casuarina/Stachyurus plants, is a carbonic anhydrase inhibitor and astringent.</p>Fórmula:C41H28O26Forma y color:SolidPeso molecular:936.65JH295 hydrate
<p>JH295 hydrate: potent, irreversible Nek2 inhibitor (IC50 = 770 nM), selective, doesn't target Cdk1, Aurora B or Plk1.</p>Fórmula:C18H18N4O3Forma y color:SolidPeso molecular:338.36Colistin adjuvant-2
<p>Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].</p>Fórmula:C14H7Cl2F3N2OForma y color:SolidPeso molecular:347.12SI-109
CAS:<p>SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.</p>Fórmula:C40H44F2N7O9PPureza:98%Forma y color:SolidPeso molecular:835.79DNA crosslinker 4 dihydrochloride
CAS:<p>DNA Crosslinker 4 binds DNA's minor groove, inhibits NCI-H460, A2780, MCF-7 cancer cells, and is used in cancer research.</p>Fórmula:C16H24Cl2N8OForma y color:SolidPeso molecular:415.32L-threo-Sphingosine C-18
CAS:<p>L-threo-Sphingosine C-18 is a protein kinase C inhibitor.</p>Fórmula:C18H37NO2Pureza:98%Forma y color:SolidPeso molecular:299.49DDCPPB-Glu
CAS:<p>DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.</p>Fórmula:C22H27N5O5Pureza:98%Forma y color:SolidPeso molecular:441.48PDHK-IN-3
<p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>Fórmula:C17H16N2O2Forma y color:SolidPeso molecular:280.32Antitumor agent-74
<p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>Fórmula:C26H23FN6Forma y color:SolidPeso molecular:438.5VEGFR-2-IN-13
<p>VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor (IC50: 3.4 nM). vEGFR-2-IN-13 arrests the HepG2 cell cycle in G2/M phase and induces apoptosis.</p>Fórmula:C24H18N6O2SForma y color:SolidPeso molecular:454.5HPK1-IN-16
CAS:<p>HPK1-IN-16, a potent HPK1 inhibitor, useful for cancer research and treatment.</p>Fórmula:C28H27FN4OForma y color:SolidPeso molecular:454.54Tenellin
CAS:<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Fórmula:C21H23NO5Forma y color:SolidPeso molecular:369.41Udifitimod
CAS:<p>Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.</p>Fórmula:C25H33NO2Forma y color:SolidPeso molecular:379.54FR 900452
CAS:<p>FR 900452 is a platelet activating factor antagonist from fermentatiion products of Streptomyces phaeofaciens.</p>Fórmula:C22H25N3O3SForma y color:SolidPeso molecular:411.52Isoleucyl tRNA synthetase-IN-2
CAS:<p>Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).</p>Fórmula:C22H33N5O8SForma y color:SolidPeso molecular:527.59LY 292728
CAS:<p>LY 292728 is a highly potent antagonist of leukotriene B4 receptor.</p>Fórmula:C34H29FO9Pureza:98%Forma y color:SolidPeso molecular:600.59Samuraciclib hydrochloride hydrate
<p>Samuraciclib (CT7001) is a potent oral CDK7 inhibitor (IC50: 41 nM) with anti-breast cancer properties.</p>Fórmula:C22H35ClN6O3Forma y color:SolidPeso molecular:521.7Mopivabil
<p>Mopivabil is the angiotensin II receptor antagonist[1].</p>Fórmula:C14H20O3Forma y color:SolidPeso molecular:236.31BM635 hydrochloride (1493762-74-5 free base)
<p>BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).</p>Fórmula:C25H30ClFN2OPureza:98%Forma y color:SolidPeso molecular:428.975-HT1A antagonist 1
<p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>Fórmula:C23H29ClN6O2Forma y color:SolidPeso molecular:456.97HER2-IN-12
<p>HER2-IN-12 is an HER2 inhibitor with an IC50 value of 121 nM and can be used to study cancers such as breast cancer.</p>Fórmula:C17H18BrN5O2SForma y color:SolidPeso molecular:436.33GNTI dihydrochloride
CAS:<p>κ opioid receptor antagonist</p>Fórmula:C27H30ClN5O3Pureza:98%Forma y color:SolidPeso molecular:508.01Dehydelone
CAS:<p>Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.</p>Fórmula:C27H39NO5SForma y color:SolidPeso molecular:489.67AChE-IN-5
<p>AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.</p>Fórmula:C38H45N5OForma y color:SolidPeso molecular:587.8Tubulin inhibitor 14
<p>Tubulin inhibitor 14 blocks NQO2 and microtubule formation, disrupts blood vessels, and may target tumors; IC50 of 1.0 μM.</p>Fórmula:C15H9F2NOForma y color:SolidPeso molecular:257.23ent-8-iso-15(S)-Prostaglandin F2α
CAS:<p>Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid.</p>Fórmula:C20H34O5Forma y color:SolidPeso molecular:354.48Piceid 6″-O-azelaic acid ester
<p>Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.</p>Fórmula:C24H36O10Forma y color:SolidPeso molecular:484.54Lunacalcipol
CAS:<p>Lunacalcipol is used for the treatment of Secondary Hyperparathyroidism.</p>Fórmula:C28H42O4SForma y color:SolidPeso molecular:474.7c-Met/HDAC-IN-2
CAS:<p>Potent dual c-Met/HDAC inhibitor, IC50: HDAC1 5.4 nM, c-Met 18.49 nM; anti-cancer, induces apoptosis, G2/M arrest in HCT-116.</p>Fórmula:C34H33N5O7Forma y color:SolidPeso molecular:623.66Tazide
<p>Tazide is an antitumor agent [1].</p>Fórmula:C12H16N4OForma y color:SolidPeso molecular:232.28TGR5 Receptor Agonist 3
CAS:<p>TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.</p>Fórmula:C29H27N3O6Forma y color:SolidPeso molecular:513.54CM-414
CAS:<p>CM-414: HDAC/PDE5 inhibitor, targeting Alzheimer’s, IC50s: PDE5 (60 nM), HDAC1/2/3/6. Reduces Aβ, pTau in mice, boosts cognition.</p>Fórmula:C23H29N5O4Pureza:98%Forma y color:SolidPeso molecular:439.51PCSK9-IN-17
CAS:<p>PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.</p>Fórmula:C16H19N5OSForma y color:SolidPeso molecular:329.42NLRP3-IN-4
<p>NLRP3-IN-4 is an effective, oral NLRP3 inflammasome inhibitor with potent anti-inflammatory effects on colitis.</p>Fórmula:C22H22N2O5Forma y color:SolidPeso molecular:394.4218-Deoxyherboxidiene
CAS:<p>18-Deoxyherboxidiene (RQN-18690A) inhibits angiogenesis, targeting SF3b in U2 snRNP spliceosome, affects HUVEC, useful for cancer research.</p>Fórmula:C25H42O5Forma y color:SolidPeso molecular:422.6ZLWT-37
<p>ZLWT-37: Oral CDK inhibitor, CDK9 IC50=0.002 µM, CDK2 IC50=0.054 µM; halts HCT116 cells at G2/M, induces apoptosis.</p>Fórmula:C26H30ClN5OForma y color:SolidPeso molecular:464ONO-5334
CAS:<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Fórmula:C21H34N4O4SPureza:98.22% - 99.60%Forma y color:SolidPeso molecular:438.58(2S,3R)-LP99
CAS:<p>(2S,3R)-LP99 is a less active enantiomer of LP99.</p>Fórmula:C26H30ClN3O4SPureza:98%Forma y color:SolidPeso molecular:516.05FGFR4-IN-10
<p>FGFR4-IN-10 (compound 5a) is a potent, selective FGFR4 inhibitor with IC50 of 70.7 nM, sparing FGFR1-3.</p>Fórmula:C20H19F3N6O3Forma y color:SolidPeso molecular:448.4Spicamycin
CAS:<p>Spicamycin can be used as a potent inducer of differentiation of human myeloid leukemia cells (HL-60) and murine myeloid leukemia cells (M1).</p>Fórmula:C30H51N7O7Forma y color:SolidPeso molecular:621.77Keap1-Nrf2-IN-4
<p>Keap1-Nrf2-IN-4 hinders MGC-803 cell growth (IC50=2.55μM), migration, and induces apoptosis with low toxicity.</p>Fórmula:C26H34N2OForma y color:SolidPeso molecular:390.56Antimalarial agent 2
<p>Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.</p>Fórmula:C27H25N3O5Forma y color:SolidPeso molecular:471.5FTO-IN-5
CAS:<p>FTO-IN-5 is a potent, selective inhibitor targeting the fat mass obesity-associated protein (FTO).</p>Fórmula:C23H18Cl2N6O6Forma y color:SolidPeso molecular:545.33CPPG
CAS:CPPG: potent group II/III mGlu receptor antagonist, 20x more selective for group III (IC50: 2.2 nM) than II (46.2 nM) in rat cortex.Fórmula:C11H14NO5PForma y color:SolidPeso molecular:271.21AKT-IN-11
<p>AKT-IN-11 is one of the most potent antibacterial agents against human hepatocellular carcinoma Bel-7402 cell line (IC50: 1.15 μM).</p>Fórmula:C27H27ClF3NO4Forma y color:SolidPeso molecular:521.96FW 34569
CAS:<p>FW 34569, an enkephalin analog, boosts growth hormones and prolactin, reduces cortisol and LH; FSH stable.</p>Fórmula:C30H43N5O7SPureza:98%Forma y color:SolidPeso molecular:617.76Mesulergine
CAS:<p>Mesulergine is metabolized into dopaminergic agonists.</p>Fórmula:C18H26N4O2SForma y color:SolidPeso molecular:362.49A1/A3 AR antagonist 1
<p>Compound 10 is a potent dual A1/A3 AR antagonist, with Ki values of 37.6 nM (hA1), 25.4 nM (hA3), and 1.47 nM (rA1), studied in renal, lung, and Alzheimer's.</p>Fórmula:C24H18N2O3SForma y color:SolidPeso molecular:414.48Aquayamycin
CAS:<p>Aquayamycin is an anthraquinone derivative and inhibitor of the enzyme tyrosine hydroxylase..</p>Fórmula:C25H26O10Forma y color:SolidPeso molecular:486.47Topoisomerase I/II inhibitor 2
<p>Compound 1a inhibits Topoisomerase I/II, shrinks mouse liver tumors, IC50: 6.83/9.82 μM for LM9/Huh7 cells.</p>Fórmula:C19H16N2O4Forma y color:SolidPeso molecular:336.34Antimalarial agent 7
<p>Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.</p>Fórmula:C23H22F2N4O3Forma y color:SolidPeso molecular:440.44CXCR4 probe 1
CAS:<p>CXCR4 probe 1, a specific PET tracer, targets CXCR4 with antagonist TN14003 (IC50: 6.9 nM), aiding in imaging CXCR4-related diseases and tumors.</p>Fórmula:C24H30FN5O4SForma y color:SolidPeso molecular:502.59CU-2010
CAS:<p>CU-2010 is a synthetic compound that reduces blood loss and aids recovery post-cardiac surgery.</p>Fórmula:C37H42N6O6SForma y color:SolidPeso molecular:698.83Epiderstatin
CAS:<p>Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.</p>Fórmula:C15H20N2O4Forma y color:SolidPeso molecular:292.335-HT6/5-HT2AR antagonist-1
<p>Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.</p>Fórmula:C21H26N6SForma y color:SolidPeso molecular:394.54LSD1/2-IN-3
<p>LSD1/2-IN-3 selectively inhibits LSD1 (Ki 11 nM) over LSD2 (Ki 7 μM), and hinders tumor stem cell proliferation.</p>Fórmula:C9H8BrF2NForma y color:SolidPeso molecular:248.07KRAS inhibitor-8
CAS:<p>KRAS inhibitor-8 is a potent KRAS G12C inhibitor.</p>Fórmula:C26H24ClF4N5O3Pureza:98%Forma y color:SolidPeso molecular:565.95Rimegepant sulfate hydrate
CAS:<p>Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.</p>Fórmula:C56H64F4N12O13SForma y color:SolidPeso molecular:1221.2526URAT1 inhibitor 2
<p>URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.</p>Fórmula:C21H18BrN3O2SForma y color:SolidPeso molecular:456.36TTT 3002
CAS:<p>TTT 3002: oral FLT3 inhibitor for AML research, blocks D835 mutations, potent at 0.2 nM IC50.</p>Fórmula:C27H23N5O3Forma y color:SolidPeso molecular:465.50A 70450
CAS:<p>A 70450, an inhibitor of aspartyl proteinase, can be used as an antifungal agent and may have a role in HIV protease inhibition therapy.</p>Fórmula:C42H71ClN6O5Pureza:98%Forma y color:SolidPeso molecular:775.50AZ0108
CAS:<p>AZ0108, an oral PARP1,2,6 inhibitor, selectively blocks centrosome clustering, is viable for in vivo studies, and doesn't inhibit PARP3/TNKS1.</p>Fórmula:C24H20F4N6O2Forma y color:SolidPeso molecular:500.45Anticancer agent 29
<p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>Fórmula:C22H15ClFNOForma y color:SolidPeso molecular:363.81UB 165
CAS:<p>Subtype-selective nicotinic agonist</p>Fórmula:C13H15ClN2Pureza:98%Forma y color:SolidPeso molecular:234.72Cilazapril HCl
CAS:<p>Cilazapril, also known as Ro 31 2848, is a potent ACE inhibitor used for hypertension.</p>Fórmula:C22H32ClN3O5Forma y color:SolidPeso molecular:453.96Tubulin polymerization-IN-33
<p>Tubulin-IN-33, an oxazoloisoindole, hinders microtubule assembly; effective against NCI cancer cells.</p>Fórmula:C27H28N2O6Forma y color:SolidPeso molecular:476.52Monoamine oxidase/Aromatase-IN-1
<p>Compound 2q: Dual MAO/aromatase inhibitor; IC50: 39 nM (MAO-B), 31 nM (aromatase). Useful in neurological/breast cancer research.</p>Fórmula:C19H19N3O3SForma y color:SolidPeso molecular:369.44PD-1-IN-17
CAS:<p>PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.</p>Fórmula:C13H22N6O7Pureza:99.6%Forma y color:SolidPeso molecular:374.35(-)-Cevimeline hydrochloride hemihydrate
<p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>Fórmula:C10H19ClNO1·5SPureza:98%Forma y color:SolidPeso molecular:244.78Antibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Fórmula:C16H23N3S2Forma y color:SolidPeso molecular:321.5SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Fórmula:C27H30N4O2SForma y color:SolidPeso molecular:474.62LA-810
CAS:<p>LA-810 is a nitrous oxide donor.</p>Fórmula:C15H25N5O7SForma y color:SolidPeso molecular:419.45CDK9-IN-11
CAS:<p>CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1].</p>Fórmula:C20H25N3O4Pureza:98%Forma y color:SolidPeso molecular:371.432-Methylsorbinol
CAS:<p>2-Methylsorbinol is a bioactive chemical.</p>Fórmula:C12H11FN2O3Forma y color:SolidPeso molecular:250.235(S),6(R)-DiHETE
CAS:<p>5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47SSM3 TFA
CAS:<p>SSM3 TFA is a potent furin inhibitor, blocking furin-dependent cell surface processing of anthrax protective antigen-83 in vitro..</p>Fórmula:C22H32N12O2Forma y color:SolidPeso molecular:496.57Antitubercular agent-13
<p>Compound 3d: antitubercular, MIC 0.007 μg/mL vs MTB H37Rv, 1.851 μg/mL vs MDR-MTB 16833, metabolically unstable.</p>Fórmula:C18H18N4O5Forma y color:SolidPeso molecular:370.36RMG8-8
<p>RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).</p>Fórmula:C41H78N8O5Forma y color:SolidPeso molecular:763.11KF26777
CAS:<p>KF26777 is a potent and selective antagonist of adenosine A3 receptor.</p>Fórmula:C16H16BrN5OPureza:98%Forma y color:SolidPeso molecular:374.23LAF-153
CAS:<p>LAF-153 is a reversible Methionine Aminopeptidase‑2 (MetAP-2) Inhibitor.</p>Fórmula:C18H32N2O7Forma y color:SolidPeso molecular:388.46Calphostin A
CAS:<p>Calphostins, from Cladosporium fungus, inhibit PKC; calphostin C is most potent, used as a biochemical tool.</p>Fórmula:C44H38O12Forma y color:SolidPeso molecular:758.77Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Fórmula:C29H31ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:590.04Nolpitantium Free Base
CAS:<p>Nolpitantium is a potent, selective NK1 receptor antagonist that inhibits substance P without affecting NK2/NK3 receptors.</p>Fórmula:C37H45Cl2N2O2Forma y color:SolidPeso molecular:620.67STA 2
CAS:<p>STA 2 is an analogue of TXA2, a thromboxane receptor in the colonic epithelium.</p>Fórmula:C21H34O3SForma y color:SolidPeso molecular:366.56DHU-Se1
<p>DHU-Se1: potent anti-inflammatory, releases reactive selenium from macrophages, inhibits iNOS/TNF-α, blocks M0 to M1 polarization.</p>Fórmula:C23H23N3OSSeForma y color:SolidPeso molecular:468.47Cilazaprilat
CAS:<p>Cilazaprilat is the active metabolite of cilazapril, a pyridazine angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.</p>Fórmula:C20H27N3O5Forma y color:SolidPeso molecular:389.45T-3764518
CAS:<p>T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).</p>Fórmula:C20H17F6N5O2Pureza:98%Forma y color:SolidPeso molecular:473.37FGFR1 inhibitor-6
<p>FGFR1 inhibitor-6, IC50: 16.31 nM, blocks cell cycle at pro-G1/G2/M and induces apoptosis.</p>Fórmula:C27H19N5O4S2Forma y color:SolidPeso molecular:541.6CDK7/12-IN-1
CAS:<p>CDK7/12-IN-1 is a selective CDK7 (IC50: 3 nM) and CDK12 (IC50: 277 nM) inhibitor, effective against tumor growth.</p>Fórmula:C25H34N8OForma y color:SolidPeso molecular:462.59Chitin synthase inhibitor 7
<p>Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.</p>Fórmula:C24H25N3O5Forma y color:SolidPeso molecular:435.47Keap1-Nrf2-IN-1 TFA
<p>Keap1-Nrf2-IN-1 TFA (compound35) is a potent inhibitor (IC50: 43 nM) protecting against acetaminophen liver damage.</p>Fórmula:C26H25F3N2O9SForma y color:SolidPeso molecular:598.54hCA VB-IN-1
<p>hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].</p>Fórmula:C9H13N3O4SForma y color:SolidPeso molecular:259.28Lasonolide A
CAS:<p>Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.</p>Fórmula:C41H60O9Forma y color:SolidPeso molecular:696.91GSK2578999A
CAS:<p>GSK2578999A is a betulin derivative with antitumor activity.</p>Fórmula:C46H62ClNO7Pureza:98%Forma y color:SolidPeso molecular:776.44KRAS inhibitor-13
CAS:<p>KRAS inhibitor-13 blocks KRAS G12C (IC50: 0.883 μM) and p-ERK in some cancer cells; promising for pancreatic, colorectal, lung cancer research.</p>Fórmula:C25H19ClFN3O2SForma y color:SolidPeso molecular:479.95Anti-inflammatory agent 9
<p>Benzimidazothiazole-derived Compound 28 from tilomisole targets COX-2, has potent anti-inflammatory effects & is orally bioavailable.</p>Fórmula:C18H15N5O2SForma y color:SolidPeso molecular:365.41WEHI-539
CAS:<p>WEHI-539 is a selective Bcl-XL inhibitor (IC50: 1.1 nM).</p>Fórmula:C31H29N5O3S2Pureza:98%Forma y color:SolidPeso molecular:583.72NITD-688
CAS:<p>NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.</p>Fórmula:C25H32N4O3S2Forma y color:SolidPeso molecular:500.68MRGPRX1 agonist 3
<p>Compound 1f, a potent MRGPRX1 agonist, has an EC50 of 0.22 μM, useful for neuropathic pain studies.</p>Fórmula:C14H11FN2OSForma y color:SolidPeso molecular:274.31DSP-6952
CAS:<p>DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.</p>Fórmula:C21H32BrClN4O5Forma y color:SolidPeso molecular:535.86T01-1
CAS:<p>T01-1, a derivative of camptothecin, is an anticancer agent demonstrating significant anti-proliferative activity.</p>Fórmula:C26H29N3O6SForma y color:SolidPeso molecular:511.59MtTMPK-IN-1
<p>MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.</p>Fórmula:C22H24N4O3Forma y color:SolidPeso molecular:392.45LY309887
CAS:<p>LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.</p>Fórmula:C19H23N5O6SForma y color:SolidPeso molecular:449.48RS 12254
CAS:<p>RS 12254 is a dopamine agonist and antihypertensive agent.</p>Fórmula:C28H40N2O4Pureza:98%Forma y color:SolidPeso molecular:468.63SM-433 hydrochloride
<p>SM-433 hydrochloride, a Smac mimetic & IAP inhibitor, binds XIAP BIR3; potent IC50 <1 μM. (Patent WO2008128171A2)</p>Fórmula:C32H44ClN5O4Forma y color:SolidPeso molecular:598.18IRE1α kinase-IN-5
<p>IRE1α kinase-IN-5 (compound 7) is a potent inhibitor of IRE1α (Ki: 98 nM) and is an ATP-competitive ligand for IRE1α.</p>Fórmula:C28H30N6O3SForma y color:SolidPeso molecular:530.64SSR-241586
CAS:<p>SSR-241586: Neurokinin antagonist, treats depression, schizophrenia, urinary issues, emesis, IBS.</p>Fórmula:C32H42Cl2N4O3Pureza:98%Forma y color:SolidPeso molecular:601.61Mu opioid receptor antagonist 3
<p>Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.</p>Fórmula:C25H28N2O4SForma y color:SolidPeso molecular:452.57Dup-714
CAS:<p>Dup-714 is a thrombin inhibitor.</p>Fórmula:C21H33BN6O5Pureza:98%Forma y color:SolidPeso molecular:460.33β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Fórmula:C31H23NO8Forma y color:SolidPeso molecular:537.52Ketomethylenebestatin
CAS:<p>Ketomethylenebestatin, a weaker carba-analog of aminopeptidase inhibitor bestatin, is 10x less potent.</p>Fórmula:C17H25NO4Pureza:98%Forma y color:SolidPeso molecular:307.38NAZ2329
CAS:<p>NAZ2329: Cell-permeable, targets R5 RPTPs, inhibits hPTPRZ1 (IC50=7.5 μM) & hPTPRG (IC50=4.8 μM), hampers glioblastoma growth, affects stem cell traits.</p>Fórmula:C21H18F3NO4S3Forma y color:SoildPeso molecular:501.56Implitapide
CAS:<p>Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).</p>Fórmula:C35H37N3O2Pureza:98%Forma y color:SolidPeso molecular:531.69NS2B/NS3-IN-3
CAS:<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Fórmula:C19H21N3O2Forma y color:SolidPeso molecular:323.39IL-17 modulator 5
CAS:<p>IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM .</p>Fórmula:C28H23F6N9O2Forma y color:SolidPeso molecular:631.53JAK3-IN-11
CAS:<p>JAK3-IN-11: potent oral JAK3 inhibitor (IC50=1.7 nM), noncytotoxic, >588-fold selectivity, blocks T-cell growth; useful in autoimmune research.</p>Fórmula:C23H23N5O2Forma y color:SolidPeso molecular:401.46SPR719
CAS:<p>SPR719 is an inhibitor of gyrase B, has bactericidal activity.</p>Fórmula:C21H25FN6O3Pureza:98%Forma y color:SolidPeso molecular:428.46HDAC10-IN-2
<p>HDAC10-IN-2, a selective HDAC10 inhibitor (IC50=20nM), modulates autophagy in FLT3-ITD+ acute myeloid leukemia.</p>Fórmula:C19H22N2O2Forma y color:SolidPeso molecular:310.39KRAS G12C inhibitor 50
CAS:<p>KRAS G12C inhibitor 50 is a KRAS G12C inhibitor (IC50: 46.7 nM).</p>Fórmula:C31H34N8O2Forma y color:SolidPeso molecular:550.65ONO-DI-004
CAS:<p>ONO-DI-004 is a selective EP1 Prostanoid receptor agonist.</p>Fórmula:C24H38O6Forma y color:SolidPeso molecular:422.55MRS4458
CAS:<p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>Fórmula:C24H20F3N5O3SPureza:98%Forma y color:SolidPeso molecular:515.51MALT1-IN-5
CAS:<p>MALT1-IN-5 is a potent inhibitor of the MALT1 protease and can be used in cancer research.</p>Fórmula:C17H17ClF2N6O3Forma y color:SolidPeso molecular:426.80DS89002333
<p>DS89002333: oral PRKACA inhibitor with 0.3 nM IC50, effective against FL-HCC with DNAJB1-PRKACA fusion in xenografts.</p>Fórmula:C22H20ClF2N3O3Forma y color:SolidPeso molecular:447.86STING agonist-7
<p>STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1].</p>Fórmula:C17H12N4O4Forma y color:SolidPeso molecular:336.3AX15910
<p>AX15910 is a potent inhibitor of BRD4 and ERK5.</p>Fórmula:C32H38N6O3Forma y color:SolidPeso molecular:554.7Quorum Sensing-IN-1
<p>Quorum Sensing-IN-1 is a small-molecule inhibitor of quorum sensing.</p>Fórmula:C13H10N2O2S2Forma y color:SolidPeso molecular:290.36TP-030-2
CAS:<p>TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) .</p>Fórmula:C23H21BrN4O3Forma y color:SolidPeso molecular:481.34CDK1-IN-3
<p>CDK1-IN-3 is a selective inhibitor targeting CDK1 (36.8 nM), CDK2 (305.17 nM), CDK5 (369.37 nM); used in cancer research.</p>Fórmula:C28H25ClF3N5O2Forma y color:SolidPeso molecular:555.98HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Fórmula:C25H21N5OSForma y color:SolidPeso molecular:439.53Aspochalasin M
CAS:<p>Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.</p>Fórmula:C24H35NO4Forma y color:SolidPeso molecular:401.54ORIC-101
CAS:<p>ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.</p>Fórmula:C34H47NO2Pureza:98%Forma y color:SolidPeso molecular:501.74Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Fórmula:C23H21ClFN3O5Forma y color:SolidPeso molecular:473.88CK2-IN-3
<p>CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.</p>Fórmula:C22H26N4O7Forma y color:SolidPeso molecular:458.46Tabimorelin hemifumarate
CAS:<p>orally active ghrelin receptor (GHS-R1a) agonist</p>Fórmula:C32H40N403C4H404Pureza:98%Forma y color:SolidPeso molecular:586.72Sagopilone
CAS:<p>Sagopilone: synthetic epothilone, inhibits cell division and induces apoptosis, effective in MDR tumors, not P-gp substrate.</p>Fórmula:C30H41NO6SForma y color:SolidPeso molecular:543.71MI-1481
CAS:<p>MI-1481: potent MML1 inhibitor, IC50 3.6 nM; disrupts menin-MLL1, active in MLL leukemia.</p>Fórmula:C29H30F3N7O2SPureza:98%Forma y color:SolidPeso molecular:597.65FAAH/MAGL-IN-1
<p>FAAH/MAGL-IN-1 (SIH 3) inhibits FAAH & MAGL with IC50 of 31 & 29 nM, useful in neuropathic pain research.</p>Fórmula:C15H9Cl2N3O3Forma y color:SolidPeso molecular:350.16BU09059
CAS:<p>BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).</p>Fórmula:C28H37N3O5Pureza:98%Forma y color:SolidPeso molecular:495.615-HT7R antagonist 1
<p>5-HT7R antagonist 1 is a G protein-biased antagonist with Ki of 6.5 nM for 5-HT 7R.</p>Fórmula:C14H18Cl2N4Forma y color:SolidPeso molecular:313.23CS-003 Free base
CAS:<p>CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.</p>Fórmula:C34H38Cl2N2O6SPureza:98%Forma y color:SolidPeso molecular:673.65DNA gyrase B-IN-1
<p>DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.</p>Fórmula:C23H18ClF3N6O4SForma y color:SolidPeso molecular:566.94Thalicarpine
CAS:<p>Thalicarpine, a natural anticancer alkaloid, inhibits p-glycoprotein and induces DNA damage, arresting cell cycle.</p>Fórmula:C41H48N2O8Forma y color:SolidPeso molecular:696.83ZIKV-IN-5
<p>ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.</p>Fórmula:C36H45NO4SiForma y color:SolidPeso molecular:583.83HDAC1-IN-5
<p>HDAC1-IN-5 inhibits HDAC1 (IC50=15 nM) & HDAC6 (IC50=20 nM), promotes apoptosis, damages chromatin, and reduces tumor growth in mice.</p>Fórmula:C20H21N3O2SForma y color:SolidPeso molecular:367.46BI 224436
CAS:<p>BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.</p>Fórmula:C27H26N2O4Forma y color:SolidPeso molecular:442.51MB-7133
CAS:<p>MB-7133 is an inhibitor of DNA synthesis.</p>Fórmula:C17H21N4O8PPureza:98%Forma y color:SolidPeso molecular:440.34JAK-2/3-IN-3
<p>JAK-2-/3-IN-3 (ST4j) is a potent JAK2/3 inhibitor for leukemia research, with IC50s: JAK2, 13 nM; JAK3, 14.86 nM; induces apoptosis.</p>Fórmula:C13H10Cl2N4O2Forma y color:SolidPeso molecular:325.15HCV-IN-40
CAS:<p>HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.</p>Fórmula:C21H26BrFN3O9PForma y color:SolidPeso molecular:594.32Lysyllysyllysine
CAS:<p>Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.</p>Fórmula:C18H38N6O4Pureza:98%Forma y color:SolidPeso molecular:402.53Novokinin
CAS:<p>Angiotensin AT2 receptor agonist</p>Fórmula:C39H61N11O7Pureza:98%Forma y color:SolidPeso molecular:795.97PARP10/15-IN-3
<p>Compound 8a, a dual PARP10 & PARP15 inhibitor, has IC50s: PARP10 at 0.14μM & PARP15 at 0.40μM; it's cell-permeable & anti-apoptotic.</p>Fórmula:C12H12N2O3Forma y color:SolidPeso molecular:232.24PDE4B/7A-IN-2
CAS:<p>5-HT1A/5-HT7 antagonist; 5-HT1A Ki=8 nM, 5-HT7 Ki=451 nM; PDE4B IC50=80.4 μM, PDE7A IC50=151.3 μM; stronger than escitalopram.</p>Fórmula:C25H35N3O2Forma y color:SolidPeso molecular:409.56PDE-I2
CAS:<p>PDE-I2 is a parasite schizogony inhibitor.</p>Fórmula:C25H23N5O8Forma y color:SolidPeso molecular:521.48Omesdafexor
CAS:<p>Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.</p>Fórmula:C34H43N3O3Forma y color:SolidPeso molecular:541.72PTP1B-IN-18
<p>PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.</p>Fórmula:C26H19N3O4SForma y color:SolidPeso molecular:469.51AS1940477
CAS:<p>AS1940477 selectively inhibits p38 MAPK α/β, blocks proinflammatory cytokines in cells, and has anti-inflammatory effects in rats.</p>Fórmula:C24H22FN5O2Forma y color:SolidPeso molecular:431.46XIAP/cIAP1 antagonist-1
<p>Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.</p>Forma y color:SolidRo 31-8472
CAS:<p>Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.</p>Fórmula:C20H27N3O6Pureza:98%Forma y color:SolidPeso molecular:405.44LMD-A
CAS:<p>LMD-A, also known as CCR8 antagonist LMD-A, is a CCR8 antagonist.</p>Fórmula:C27H32N4O4SForma y color:SolidPeso molecular:508.63BCL6-IN-9
CAS:<p>BCL6-IN-9 (compound 1) is a potent inhibitor of B-cell lymphoma 6 protein (BCL6) (IC50: 3.9 nM) and can be used to study cancer.</p>Fórmula:C22H18ClF2N5O2Forma y color:SolidPeso molecular:457.86Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Fórmula:C25H18N2O2SForma y color:SolidPeso molecular:410.49AL 8810
CAS:<p>AL-8810 is an 11β-fluoro analog of PGF 2α with selective antagonist effects at the PGF 2α receptor (FP receptor) [1].</p>Fórmula:C24H31FO4Forma y color:SolidPeso molecular:402.5NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Fórmula:C14H9IN2O3SForma y color:SolidPeso molecular:412.2PARP7-IN-12
CAS:<p>PARP7-IN-12, a potent inhibitor targeting PARP7, exhibits an IC50 of 7.836 nM. This compound is applicable in cancer research.</p>Fórmula:C23H27ClF3N5O5Forma y color:SolidPeso molecular:545.94TAK-828F
CAS:<p>TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.</p>Fórmula:C28H32FN3O5Pureza:98%Forma y color:SolidPeso molecular:509.57D18
CAS:<p>D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.</p>Fórmula:C21H28N6Forma y color:SolidPeso molecular:364.49YKL-1-116
CAS:<p>YKL-1-116 is an effective, selective, and covalent CDK7 inhibitor.</p>Fórmula:C34H38N8O3Pureza:98%Forma y color:SolidPeso molecular:606.72Transthyretin-IN-1
<p>Transthyretin-IN-1 inhibits TTR fibril formation, aiding Alzheimer’s research.</p>Fórmula:C10H9Br2NO4Forma y color:SolidPeso molecular:366.99AZD 4407
CAS:<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Fórmula:C19H21NO3S2Pureza:98%Forma y color:SolidPeso molecular:375.5XPO1-IN-1
<p>XPO1-IN-1: an oral MM.1S cell inhibitor (IC50: 24 nM), induces apoptosis, stable metabolism, good pharmacokinetics.</p>Fórmula:C20H15F6N5O3SForma y color:SolidPeso molecular:519.42Z-FY-CHO
CAS:<p>Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.</p>Fórmula:C26H26N2O5Pureza:95.88%Forma y color:SolidPeso molecular:446.5FT3967385
<p>FT3967385: New USP30 inhibitor boosts mitochondrial ubiquitylation via PINK1-PARKIN.</p>Fórmula:C21H19N5O2Forma y color:SolidPeso molecular:373.41URAT1 inhibitor 3
<p>URAT1 inhibitor 3: potent oral URAT1 blocker, IC50=0.8 nM, for gout/hyperuricemia study.</p>Fórmula:C14H8Cl2N2O2Forma y color:SolidPeso molecular:307.13Anti-inflammatory agent 10
<p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>Fórmula:C17H13BrN4O3S2Forma y color:SolidPeso molecular:465.34VEGFR-2-IN-5 hydrochloride
<p>VEGFR-2-IN-5 hydrochloride is an effective VEGFR2 inhibitor.</p>Fórmula:C19H25ClN8Forma y color:SolidPeso molecular:400.91CRM1 degrader 1
<p>CRM1 degrader 1 (1l) is a low-toxic CRM1 degrader that induces apoptosis in gastric carcinoma and selectively inhibits the proliferation of gastric cancer[1].</p>Fórmula:C16H20O3Forma y color:SolidPeso molecular:260.33Tubulin inhibitor 15
<p>Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 15 exhibits cytotoxicity in HepG2 cells [1].</p>Fórmula:C16H12FNO2Forma y color:SolidPeso molecular:269.27GnRH-R antagonist 1
CAS:<p>Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.</p>Fórmula:C31H28F5N7O6SPureza:98%Forma y color:SolidPeso molecular:721.65EGFR-IN-58
<p>EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.</p>Fórmula:C31H30FN7OForma y color:SolidPeso molecular:535.61RIP1 kinase inhibitor 1
CAS:<p>RIP1 kinase inhibitor 1 is an orally available and brain-penetrating inhibitor of RIP1 kinase with pKi of 9.04.</p>Fórmula:C24H20ClN5O3Pureza:98%Forma y color:SolidPeso molecular:461.9LSD1-IN-22
<p>LSD1-IN-22: potent LSD1 inhibitor, K_i 98 nM, curbs cancer cell growth.</p>Fórmula:C9H8BrF2NForma y color:SolidPeso molecular:248.07PF-00489791
CAS:<p>PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.</p>Fórmula:C20H28N8O4SPureza:99.97%Forma y color:SolidPeso molecular:476.55Ro-24-4736
CAS:<p>Ro 24-4736 is an effective and selective platelet-activating factor antagonist.</p>Fórmula:C31H20ClN5OSPureza:98%Forma y color:SolidPeso molecular:546.04RMS-07
CAS:<p>RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.</p>Fórmula:C35H40N8O2Forma y color:SolidPeso molecular:604.74NTPDase-IN-3
CAS:<p>NTPDase-IN-3 inhibits NTPDase1/2/3/8 (IC50: 0.21/1.07/0.38/0.05 μM), useful for cancer and thrombosis research.</p>Fórmula:C22H24ClN3OS2Forma y color:SolidPeso molecular:446.03Cbl-b-IN-1
CAS:<p>Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.</p>Fórmula:C29H34N6O2Pureza:99.68%Forma y color:SolidPeso molecular:498.631OncoFAP
CAS:<p>OncoFAP is an ultra-high affinity fibroblast activating protein (FAP) ligand with potential tumour targeting.</p>Fórmula:C21H19F2N5O5Pureza:99.77%Forma y color:SolidPeso molecular:459.40
