Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.781 productos)
- Apoptosis(6.260 productos)
- Ciclo celular / Checkpoint(4.792 productos)
- Cromatina / Epigenética(2.440 productos)
- Señalización citoesquelética(1.527 productos)
- Daño al ADN / Reparación del ADN(2.968 productos)
- Endocrinología / Hormonas(3.706 productos)
- Enzima(3.667 productos)
- GPCR / proteína G(9.005 productos)
- Inmunología e inflamación(3.874 productos)
- Virus de la gripe(301 productos)
- Señalización JAK / STAT(414 productos)
- Señalización MAPK(1.248 productos)
- Transportador de membrana / canal de iones(3.033 productos)
- Metabolismo(10.207 productos)
- Microbiología / Virología(7.591 productos)
- Neurociencia(10.382 productos)
- Otros inhibidores(36.042 productos)
- Reducción de oxidación(42 productos)
- Señalización PI3K / Akt / mTOR(1.444 productos)
- Proteasas / Proteasoma(1.724 productos)
- Células madre y Derivados(825 productos)
- Tirosina quinasa / adaptadores(2.035 productos)
- Ubiquitinación(1.717 productos)
Mostrar 16 subcategorías más
Se han encontrado 66686 productos de "Inhibidores"
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LCB-2853
CAS:LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.Fórmula:C21H24ClNO4SPureza:97.15%Forma y color:SolidPeso molecular:421.94CLP257
CAS:<p>CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.</p>Fórmula:C14H14FN3O2SPureza:99.5%Forma y color:SolidPeso molecular:307.34Cymipristone
CAS:Cymipristone, a progesterone receptor antagonist, is used potentially for termination of intrauterine pregnancy.Fórmula:C34H43NO2Pureza:98%Forma y color:SolidPeso molecular:497.71WAY-658494
CAS:WAY-658494 is an (active) compound.Fórmula:C13H13NO3S2Forma y color:SolidPeso molecular:295.38Tubulin/JAK2-IN-1
CAS:Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significantFórmula:C22H20N6O3Forma y color:SolidPeso molecular:416.43Quetiapine sulfoxide hydrochloride
Quetiapine sulfoxide hydrochloride is a main metabolite of Quetiapinem. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.Fórmula:C21H26ClN3O3SPureza:98%Forma y color:SolidPeso molecular:435.97CDK9-IN-23
CAS:CDK9-IN-23 (Example 4) is a potent inhibitor of CDK9, exhibiting an IC50 value of less than 20 nM [1].Fórmula:C22H25ClN4O3Pureza:98%Forma y color:SolidPeso molecular:428.91Antitumor agent-67
CAS:Antitumor agent-67 (compound 3), a potent antitumor agent, exhibits highly selective toxicity toward cancer cells while sparing normal cells.Fórmula:C45H47NO13Forma y color:SolidPeso molecular:809.85Bisnorcymserine
CAS:Bisnorcymserine reversibly inhibits butyrylcholinesterase, binding Ser(200) and His(440) non-covalently and stacking with Trp(84).Fórmula:C21H25N3O2Pureza:98%Forma y color:SolidPeso molecular:351.44RET-IN-25
CAS:RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor that demonstrates efficacy against medullary thyroid carcinoma (MTC), exhibiting half-maximalFórmula:C22H17N3O5SForma y color:SolidPeso molecular:435.45M-0002
CAS:M-0002, a vasopressin V2 receptor antagonist, is used potentially for the treatment of ascites.Fórmula:C32H29Cl2N3O3Forma y color:SolidPeso molecular:574.5Adipiplon
CAS:Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Fórmula:C18H18FN7Forma y color:SolidPeso molecular:351.38Difelikefalin TFA
CAS:Difelikefalin: KOR agonist, EC50 of 0.16 nM in humans, inhibits cAMP (EC50=0.048 nM), selective over MOR, reduces pain and itching in mice.Fórmula:C42H56F9N7O12Forma y color:SolidPeso molecular:1021.92Fenpropidin
CAS:Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.Fórmula:C19H31NPureza:98.58% - 99.54%Forma y color:SolidPeso molecular:273.46UNC9994 hydrochloride
CAS:UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.Fórmula:C21H23Cl3N2OSForma y color:SolidPeso molecular:457.84VULM 1457
CAS:VULM 1457 is a potent ACAT inhibitor.Fórmula:C25H27N3O3SPureza:99.73%Forma y color:SolidPeso molecular:449.57LTB4 antagonist 2
CAS:LTB4 antagonist 2, a carboxamide-acid compound, serves as an antagonist to leukotriene B4 (LTB4), possessing potential anti-inflammatory properties.Fórmula:C26H23NO6Pureza:98%Forma y color:SolidPeso molecular:445.46CBP/p300-IN-5
CAS:P300/CBP-IN-5 is a potent inhibitor of p300/CBP histone acetyltransferase (IC50 of 18.8 nM).Fórmula:C29H27F5N6O4Pureza:98%Forma y color:SolidPeso molecular:618.55SWTX-143
CAS:SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptionalFórmula:C19H18F3N3OPureza:98%Forma y color:SolidPeso molecular:361.36NLRP3-IN-21
CAS:NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties.Fórmula:C20H13Cl2F3N6O2SPureza:98%Forma y color:SolidPeso molecular:529.32Himbacine
CAS:Himbacine is a muscarine receptor antagonist.Fórmula:C22H35NO2Forma y color:SolidPeso molecular:345.52GX-395
CAS:GX-395 is a novel Nav1.7 inhibitor.Fórmula:C21H17ClF2N6O3S2Pureza:98%Forma y color:SolidPeso molecular:538.98DL-01
CAS:DL-01 is a drug-linker conjugate for antibody-drug conjugates (ADCs), utilized in the synthesis of ADCs [1].Fórmula:C55H71N9O13SForma y color:SolidPeso molecular:1098.27DPP-4/GPR119 modulator 2
CAS:DPP-4/GPR119 modulator 2 is an inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50: 0.22 μM) and an agonist of GPR119 (EC50: 0.95 μM).Fórmula:C30H40N8O3Forma y color:SolidPeso molecular:560.69L 663581
CAS:L 663581 is the benzodiazepine receptor partial agonist.Fórmula:C17H16ClN5O2Pureza:98%Forma y color:SolidPeso molecular:357.79LY2922470
CAS:LY2922470: Selective GPR40 agonist; EC50=7nM (human), 1nM (mouse), 3nM (rat); lowers glucose, boosts insulin/GLP-1.Fórmula:C28H29NO4SPureza:95.11% - 97.08%Forma y color:SolidPeso molecular:475.6Ref: TM-T15810
1mg103,00€5mg236,00€10mg354,00€25mg617,00€50mg879,00€100mg1.198,00€200mg1.605,00€1mL*10mM (DMSO)248,00€Antituberculosis agent-8
CAS:Antituberculosis agent-8: MIC 3.53 μM vs M. tuberculosis, antifungal MIC 62.50 μM vs A. niger.Fórmula:C25H19F3N2O3Forma y color:SolidPeso molecular:452.43SR10067
CAS:SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.Fórmula:C31H31NO3Pureza:99.57%Forma y color:SolidPeso molecular:465.58Ref: TM-T12998
1mg58,00€5mg134,00€10mg207,00€25mg353,00€50mg510,00€100mg658,00€200mg905,00€1mL*10mM (DMSO)144,00€CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Fórmula:C18H22Cl2NO3PForma y color:SolidPeso molecular:402.25HDAC-IN-50
CAS:HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.Fórmula:C31H41N7O4Forma y color:SolidPeso molecular:575.7MK-287
CAS:MK-287 is a PAF antagonist blocking [3H]C18-PAF binding to platelets, PMNs, and lungs; may treat asthma.Fórmula:C25H34O9SForma y color:SolidPeso molecular:510.6IRAK4-IN-28
CAS:IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme.Fórmula:C27H31N9O3Pureza:98%Forma y color:SolidPeso molecular:529.59SORT-PGRN interaction inhibitor 2
CAS:SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in variousFórmula:C19H31NOForma y color:SolidPeso molecular:289.46Anticancer agent 81
CAS:Compound 37b3, an anticancer, halts tumor growth, triggers cell death, and pairs with Trastuzumab to form T-PBA, an ADC with targeted delivery.Fórmula:C46H46N6O5Pureza:98%Forma y color:SolidPeso molecular:762.89SOS1-IN-8
CAS:SOS1-IN-8 is an inhibitor of SOS1 and acts on SOS1-G12D (IC50: 11.6 nM) and SOS1-G12V (IC50: 40.7 nM).Fórmula:C24H26F3N3O4Forma y color:SolidPeso molecular:477.48TA-1887
CAS:TA-1887: Selective SGLT2 inhibitor, treats type 2 diabetes, lowers glucose in high-fat diet mice, boosts UGE, has good pharmacokinetics.Fórmula:C24H26FNO5Forma y color:SolidPeso molecular:427.47ICMT-IN-5
CAS:ICMT-IN-5 (compound 46) is an ICMT inhibitor with an IC50 value of 0.3 μM [1].Fórmula:C22H28FNOForma y color:SolidPeso molecular:341.46RO5527239
CAS:RO5527239 is a potent, orally available GPBAR1 agonist agent.Fórmula:C28H31N3O3Pureza:98%Forma y color:SolidPeso molecular:457.56CD38 inhibitor 2
CAS:CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).Fórmula:C19H24N6O3Pureza:98.88%Forma y color:SolidPeso molecular:384.43Ref: TM-T61681
1mg187,00€5mg472,00€10mg755,00€25mg1.406,00€50mg1.882,00€100mg2.547,00€1mL*10mM (DMSO)518,00€FIKK9.1-IN-1
CAS:FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1,Fórmula:C22H22N2SePureza:98%Forma y color:SolidPeso molecular:393.38Cardanol diene
CAS:Cardanol diene: phenol in cashew shells; anti-tyrosinase (IC50=52.5μM); used to make anti-E. coli biofilm complexes.Fórmula:C21H32OForma y color:SolidPeso molecular:300.48CGA-JK3
CAS:CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.Fórmula:C15H19NO3Pureza:98%Forma y color:SolidPeso molecular:261.32L-783483
CAS:L-783483 is an agonist of PPAR.Fórmula:C22H21ClF3NO4SPureza:98%Forma y color:SolidPeso molecular:487.92Entacapone acid
CAS:Entacapone acid (AG 1290) is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).Fórmula:C10H6N2O6Pureza:98.86%Forma y color:SolidPeso molecular:250.16OM173-αA
CAS:OM173-αA is a quinone bacterial metabolite that inhibits the growth of the bacteria M.Fórmula:C17H16O6Forma y color:SolidPeso molecular:316.31Tubulin polymerization-IN-52
CAS:Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1].Fórmula:C21H18F3N5O3Forma y color:SolidPeso molecular:445.39CB2R-IN-1
CAS:CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).Fórmula:C23H27F3N4O6S3Pureza:98%Forma y color:SolidPeso molecular:608.67G-38963
CAS:G-38963 is a potent and highly specific MEK inhibitor (MEKi).Fórmula:C16H13FIN3O4Forma y color:SolidPeso molecular:457.2K-Ras G12C-IN-2
CAS:K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.Fórmula:C21H27ClN4O3Pureza:98%Forma y color:SolidPeso molecular:418.92ZD-8731 HCl
CAS:ZD-8731, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension and heart failure.Fórmula:C25H22ClN5OForma y color:SolidPeso molecular:443.93
