Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.542 productos)
- Apoptosis(5.816 productos)
- Ciclo celular / Checkpoint(4.466 productos)
- Cromatina / Epigenética(2.252 productos)
- Señalización citoesquelética(1.381 productos)
- Daño al ADN / Reparación del ADN(2.830 productos)
- Endocrinología / Hormonas(3.518 productos)
- Enzima(3.640 productos)
- GPCR / proteína G(8.362 productos)
- Inmunología e inflamación(3.540 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(405 productos)
- Señalización MAPK(1.201 productos)
- Transportador de membrana / canal de iones(2.809 productos)
- Metabolismo(9.462 productos)
- Microbiología / Virología(7.003 productos)
- Neurociencia(9.942 productos)
- Otros inhibidores(37.827 productos)
- Reducción de oxidación(40 productos)
- Señalización PI3K / Akt / mTOR(1.399 productos)
- Proteasas / Proteasoma(1.598 productos)
- Células madre y Derivados(830 productos)
- Tirosina quinasa / adaptadores(2.012 productos)
- Ubiquitinación(1.651 productos)
Mostrar 16 subcategorías más
Se han encontrado 66618 productos de "Inhibidores"
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GNE 220 hydrochloride
CAS:<p>GNE 220 (hydrochloride) is a potent and selective inhibitor of MAP4K4 (IC50: 7 nM).</p>Fórmula:C25H27ClN8Forma y color:SolidPeso molecular:474.99KRAS G12C inhibitor 5
CAS:<p>KRAS G12C inhibitor 5 is a KRas G12C inhibitor.</p>Fórmula:C32H37N7O2Pureza:98%Forma y color:SolidPeso molecular:551.68IM156
CAS:<p>IM156, a Metformin derivative, activates AMPK, enhances cognition in aging animals, and inhibits OXPHOS in solid tumor research.</p>Fórmula:C13H16F3N5OPureza:99.67%Forma y color:SolidPeso molecular:315.29PTP1B-IN-20
PTP1B-IN-20: Selective PTP1B inhibitor, IC50=1.05μM; less effective on TCPTP (IC50=78μM), targets type 2 diabetes.Fórmula:C26H28O15Forma y color:SolidPeso molecular:580.49ST1074
CAS:<p>ST1074, a dual inhibitor of CerS2 and CerS4, promotes apoptosis and is applicable in cancer research [1].</p>Fórmula:C20H36ClNO3Pureza:98%Forma y color:SolidPeso molecular:373.96Bivamelagon
CAS:<p>MC-4R Agonist 2 (Example 1), a melanocortin 4 receptor (MC4R) agonist, is employed in the research of conditions such as obesity, diabetes, inflammation, and</p>Fórmula:C35H53ClN4O4Pureza:100%Forma y color:SolidPeso molecular:629.27Labuxtinib
CAS:<p>Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].</p>Fórmula:C20H16FN5O2Pureza:99.77%Forma y color:SolidPeso molecular:377.37AMD-3329 free base
CAS:<p>AMD-3329 is a potent anti-HIV agent that blocks virus replication by targeting CXCR4, a key receptor for X4 viruses' entry.</p>Fórmula:C34H50N8Forma y color:SolidPeso molecular:570.81GSK840
CAS:<p>GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase</p>Fórmula:C21H23N3O3Pureza:99.7%Forma y color:SolidPeso molecular:365.43Wf-516
CAS:<p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>Fórmula:C25H25Cl2N3O4Pureza:98%Forma y color:SolidPeso molecular:502.39Debrisoquin
CAS:<p>Debrisoquin (Isocaramidine) is a TMPRSS2 inhibitor that prevents SARS-CoV-2 from entering human lung cells through TMPRSS2-dependent pathways, exhibiting an</p>Fórmula:C10H13N3Pureza:98%Forma y color:SolidPeso molecular:175.23CCT-251921
CAS:<p>CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).</p>Fórmula:C21H23ClN6OPureza:99.07%Forma y color:SolidPeso molecular:410.9Sulfatinib
CAS:<p>Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to</p>Fórmula:C24H28N6O3SPureza:99.21% - >99.99%Forma y color:SolidPeso molecular:480.58PU-48
CAS:<p>PU-48 is a potent inhibitor of urea transporters A (UT-A) with an IC50 value of 0.32 μM, exhibiting a significant diuretic effect in mouse models without</p>Fórmula:C14H12N2O3SForma y color:SolidPeso molecular:288.32(R)-3,4-DCPG
CAS:<p>AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors</p>Fórmula:C10H9NO6Pureza:98%Forma y color:SolidPeso molecular:239.18Antibiofilm agent-2
CAS:<p>Antibiofilm Agent-2 (Compound 4T) serves as a potent biofilm inhibitor, exhibiting an IC50 of 3.6 μM, and impairs the quorum sensing system along with iron</p>Fórmula:C17H21NO5Forma y color:SolidPeso molecular:319.35CL2E-SN38
CAS:<p>CL2E-SN-38 is a structurally stable and highly releasable antibody-drug conjugate (ADC) incorporating SN-38, the active metabolite of Irinotecan and a potent</p>Fórmula:C87H116N14O24Forma y color:SolidPeso molecular:1741.93A1AT modulator 1
CAS:<p>A1AT Modulator 1 potently inhibits Z α1-antitrypsin (A1AT) polymerization, exhibiting a pIC50 of 8.3 [1].</p>Fórmula:C21H23FN2O3Forma y color:SolidPeso molecular:370.42RORγt Inverse agonist 3
CAS:<p>RORγt Inverse agonist 3 is a potent, selective and orally active inverse agonist of RORγ(EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells),</p>Fórmula:C29H31Cl2N5O4SPureza:98%Forma y color:SolidPeso molecular:616.56CXCR4 antagonist 7
CAS:<p>Compound PARA-B, a CXCR4 antagonist with IC50 = 9.3 nM, targets HIV, cancer, inflammatory diseases, and WHIM syndrome.</p>Fórmula:C15H17N5O3Forma y color:SolidPeso molecular:315.33NLX-204
CAS:<p>NLX-204 is a selective, potent agonist of ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor with pKi value of 10.19.</p>Fórmula:C20H22ClF2N3O2Pureza:98%Forma y color:SolidPeso molecular:409.86Caroverine
CAS:Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.Fórmula:C22H27N3O2Forma y color:SolidPeso molecular:365.47NS5A-IN-3
CAS:<p>NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.</p>Fórmula:C44H44N6O8Pureza:98%Forma y color:SolidPeso molecular:784.86Dapsone hydroxylamine
CAS:<p>Dapsone hydroxylamine (DDS-NOH) promotes methemoglobinemia, impedes catalase (CAT) activity, and suppresses the generation of reactive oxygen species, while</p>Fórmula:C12H12N2O3SPureza:98%Forma y color:SolidPeso molecular:264.3HBV-IN-41
CAS:<p>HBV-IN-41 (compound 45) is a potent, orally active inhibitor of Hepatitis B Virus (HBV), exhibiting an EC50 value of 0.027μM [1].</p>Fórmula:C18H19ClFN5O3Pureza:98%Forma y color:SolidPeso molecular:407.83TA-1887
CAS:<p>TA-1887: Selective SGLT2 inhibitor, treats type 2 diabetes, lowers glucose in high-fat diet mice, boosts UGE, has good pharmacokinetics.</p>Fórmula:C24H26FNO5Forma y color:SolidPeso molecular:427.47Anti-MRSA agent 8
CAS:<p>Anti-MRSA Agent 8 (Compound 7g), a derivative of DAPG, exhibits potent antibacterial properties by interacting with bacterial cell membranes and is useful for</p>Fórmula:C20H30O5Forma y color:SolidPeso molecular:350.45CD38 inhibitor 2
CAS:<p>CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).</p>Fórmula:C19H24N6O3Forma y color:SolidPeso molecular:384.43Fiboflapon sodium
CAS:Fiboflapon sodium, an oral 5-LOX-activating protein inhibitor, binds FLAP at 2.9 nM, inhibits LTB4 at 76 nM.Fórmula:C38H43N3NaO4SForma y color:SolidPeso molecular:660.83SOS1-IN-8
CAS:<p>SOS1-IN-8 is an inhibitor of SOS1 and acts on SOS1-G12D (IC50: 11.6 nM) and SOS1-G12V (IC50: 40.7 nM).</p>Fórmula:C24H26F3N3O4Forma y color:SolidPeso molecular:477.48Antituberculosis agent-8
CAS:<p>Antituberculosis agent-8: MIC 3.53 μM vs M. tuberculosis, antifungal MIC 62.50 μM vs A. niger.</p>Fórmula:C25H19F3N2O3Forma y color:SolidPeso molecular:452.43FAAH/cPLA2α-IN-1
CAS:<p>FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (</p>Fórmula:C19H26N4O5Pureza:98%Forma y color:SolidPeso molecular:390.43Anticancer agent 113
CAS:<p>Anticancer agent 113 possesses anticancer activity [1].</p>Fórmula:C27H31ClN6O2Forma y color:SolidPeso molecular:507.03MPI8
CAS:<p>MPI8 is a SARS-CoV-2 Protease inhibitor (IC50 = 105 nM).</p>Fórmula:C32H48N4O7Forma y color:SolidPeso molecular:600.75IDO1/2-IN-1
CAS:<p>First potent oral dual IDO1/IDO2 inhibitor with antitumor properties; IC50: 28 nM (IDO1), 144 nM (IDO2).</p>Fórmula:C16H18BrFN8O4Forma y color:SolidPeso molecular:485.27Glycinexylidide
CAS:<p>Glycinexylidide (GX), the active metabolite of the local anesthetic Lidocaine, exhibits properties significant in inhibiting sodium channels with complex</p>Fórmula:C10H14N2OPureza:98%Forma y color:SolidPeso molecular:178.23SORT-PGRN interaction inhibitor 2
CAS:<p>SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in various</p>Fórmula:C19H31NOForma y color:SolidPeso molecular:289.46PAC1R antagonist 1
CAS:<p>PAC1R antagonist 1 is a PAC1 receptor antagonist that inhibits the activation of peptides by pituitary adenylate cyclase and can be used to study tumours.</p>Fórmula:C17H17ClN6O2Pureza:98.43%Forma y color:SolidPeso molecular:372.81A81988
CAS:A81988 is an antagonist of angiotensin AT1 receptors.Fórmula:C23H22N6O2Pureza:98%Forma y color:SolidPeso molecular:414.46LBT 999
CAS:<p>LBT 999 is used as a dopamine reuptake inhibitor.</p>Fórmula:C20H26FNO2Forma y color:SolidPeso molecular:331.42Enpp-1-IN-4
CAS:<p>Enpp-1-IN-4: potent enpp-1 inhibitor with potential in cancer research. See patent WO2019177971A1, compound 1.</p>Fórmula:C19H19N5O5SForma y color:SolidPeso molecular:429.45VU0364739
CAS:<p>VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].</p>Fórmula:C26H27FN4O2Pureza:98%Forma y color:SolidPeso molecular:446.52GNE-618
CAS:<p>GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM).</p>Fórmula:C21H15F3N4O3SForma y color:SolidPeso molecular:460.43(±)13,14-EDT
CAS:<p>(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance</p>Fórmula:C22H36O3Forma y color:SolidPeso molecular:348.50VT-1598 tosylate
CAS:<p>VT-1598 tosylate is a selective, orally active antifungal compound that targets CYP51. It demonstrates efficacy against C. auris.</p>Fórmula:C38H28F4N6O5SForma y color:SolidPeso molecular:756.72Fosnetupitant chloride monohydrochloride
CAS:<p>Fosnetupitant chloride monohydrochloride (Pro-netupitant chloride monohydrochloride) is a selective NK1 antagonist exhibiting high affinity for the human NK1</p>Fórmula:C31H37Cl2F6N4O5PPureza:98%Forma y color:SolidPeso molecular:761.52D-Ala-Lys-AMCA
CAS:<p>D-Ala-Lys-AMCA, a PEPT1 substrate, transports into Caco-2/liver cancer cells with blue fluorescence.</p>Fórmula:C21H28N4O6Pureza:98%Forma y color:SolidPeso molecular:432.47RIPK-IN-4
CAS:<p>RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM).</p>Fórmula:C18H21FN4O3SPureza:98%Forma y color:SolidPeso molecular:392.45LCB-2853
CAS:<p>LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.</p>Fórmula:C21H24ClNO4SPureza:97.15%Forma y color:SolidPeso molecular:421.94A 77003
CAS:<p>A 77003 is a HIV-1 protease inhibitor. A77003 impairs HIV-1 protease-mediated Gag processing.</p>Fórmula:C44H58N8O6Forma y color:SolidPeso molecular:794.98
