Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.542 productos)
- Apoptosis(5.816 productos)
- Ciclo celular / Checkpoint(4.466 productos)
- Cromatina / Epigenética(2.252 productos)
- Señalización citoesquelética(1.381 productos)
- Daño al ADN / Reparación del ADN(2.830 productos)
- Endocrinología / Hormonas(3.518 productos)
- Enzima(3.640 productos)
- GPCR / proteína G(8.362 productos)
- Inmunología e inflamación(3.540 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(405 productos)
- Señalización MAPK(1.201 productos)
- Transportador de membrana / canal de iones(2.809 productos)
- Metabolismo(9.462 productos)
- Microbiología / Virología(7.003 productos)
- Neurociencia(9.942 productos)
- Otros inhibidores(37.827 productos)
- Reducción de oxidación(40 productos)
- Señalización PI3K / Akt / mTOR(1.399 productos)
- Proteasas / Proteasoma(1.598 productos)
- Células madre y Derivados(830 productos)
- Tirosina quinasa / adaptadores(2.012 productos)
- Ubiquitinación(1.651 productos)
Mostrar 16 subcategorías más
Se han encontrado 66618 productos de "Inhibidores"
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WAY-325811
CAS:<p>WAY-325811 is an active pharmaceutical compound.</p>Fórmula:C18H18N2O2SForma y color:SolidPeso molecular:326.41TNH
CAS:<p>TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1].</p>Fórmula:C39H57ClN6O13Forma y color:SolidPeso molecular:853.36AMB639752
CAS:<p>AMB639752 is a potent inhibitor of diacylglycerol kinase alpha (DGKα) that reinstates restimulation-induced cell death (RICD) in SAP-deficient lymphocytes</p>Fórmula:C21H23N3O3Forma y color:SolidPeso molecular:365.43Antibiofilm agent-2
CAS:<p>Antibiofilm Agent-2 (Compound 4T) serves as a potent biofilm inhibitor, exhibiting an IC50 of 3.6 μM, and impairs the quorum sensing system along with iron</p>Fórmula:C17H21NO5Forma y color:SolidPeso molecular:319.35MetAP2-IN-1
CAS:<p>MetAP2-IN-1 is a selective inhibitor of MetAP2, a target involved in angiogenesis-related conditions, suitable for research applications [1].</p>Fórmula:C8H6BrN3Pureza:98%Forma y color:SolidPeso molecular:224.06FPR2 agonist 3
CAS:<p>Compound CMC23, an FPR2 agonist, mitigates lactate dehydrogenase release in LPS-stimulated cultures and reduces pro-inflammatory IL-1β and IL-6 levels.</p>Fórmula:C25H20F2N4O2Forma y color:SolidPeso molecular:446.45K-756
CAS:<p>K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 (IC50 = 31 nM) and TNKS2 (IC50 = 36 nM).</p>Fórmula:C24H27N5O3Pureza:99.81%Forma y color:SolidPeso molecular:433.5Sulfatinib
CAS:<p>Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to</p>Fórmula:C24H28N6O3SPureza:99.21% - >99.99%Forma y color:SolidPeso molecular:480.58NVP-ABJ688
CAS:<p>NVP-ABJ688 is the cysteine protease cathepsin K inhibitor.</p>Fórmula:C25H32N8OPureza:98%Forma y color:SolidPeso molecular:460.57PAK4-IN-1
CAS:<p>PAK4-IN-1: selective, potent oral PAK4 inhibitor; stable in acid/neutral; shows strong anti-tumor in vivo.</p>Fórmula:C26H30ClN7O5Forma y color:SolidPeso molecular:556.01TM2 TEAD inhibitor
CAS:<p>TM2 TEAD inhibitor, a robust and reversible inhibitor of the TEA domain transcription factor, presents dual inhibitory concentrations (IC50) of 38 nM for TEAD4</p>Fórmula:C26H33N3O3Forma y color:SolidPeso molecular:435.57INX-SM-6
CAS:<p>INX-SM-6, a chemical compound, serves as a targeted delivery vehicle for anti-inflammatory agents and has shown efficacy in suppressing LPS-induced IL-1β</p>Fórmula:C32H36N2O6SForma y color:SolidPeso molecular:576.7GABA-IN-2
CAS:<p>GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1</p>Fórmula:C12H4Cl2F6N4SeForma y color:SolidPeso molecular:468.04SARS-CoV-2 3CLpro-IN-10
<p>SARS-CoV-2 3CLpro-IN-10(5d) inhibits 3CL protease: 190 nM (SARS-CoV-2), 790 nM (SARS-CoV-1), 70 nM (MERS-CoV), and has broad-spectrum antiviral effects.</p>Fórmula:C24H33FN3NaO8SForma y color:SolidPeso molecular:565.59RXFP1 receptor agonist-6
CAS:<p>RXFP1 receptor agonist-6 (Example 7) serves as an agonist for the RXFP1 receptor and effectively suppresses cAMP production in HEK293 cells that stably express</p>Fórmula:C38H32F5N3O7Forma y color:SolidPeso molecular:737.67NBI-34041
CAS:<p>NBI-34041: High-affinity CRF1 antagonist; reduces endocrine responses to CRF challenges.</p>Fórmula:C22H26Cl2N4Forma y color:SolidPeso molecular:417.37H4R antagonist 2
CAS:<p>H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoid</p>Fórmula:C13H17N5OPureza:98%Forma y color:SolidPeso molecular:259.31ICMT-IN-33
CAS:<p>ICMT-IN-33 (compound 73) functions as an ICMT inhibitor with an IC50 value of 0.46 μM [1].</p>Fórmula:C20H24ClNOForma y color:SolidPeso molecular:329.86Yonkenafil
CAS:<p>Yonkenafil, a PDE5 inhibitor, may reduce stroke damage and aid in Alzheimer's treatment.</p>Fórmula:C24H33N5O4SForma y color:SolidPeso molecular:487.61KRIBB3
CAS:<p>KRIBB3: novel anticancer microtubule inhibitor; halts MDA-MB-231 cell migration/invasion by targeting Hsp27 phosphorylation.</p>Fórmula:C19H19NO4Forma y color:SolidPeso molecular:325.36Kv3 modulator 3
CAS:<p>Kv3 modulator 3 is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels .has analgesic activity for use in the prophylaxis o or treatment of pain.</p>Fórmula:C19H18N4O3Pureza:98%Forma y color:SolidPeso molecular:350.37PF-07059013
CAS:<p>PF-07059013, an orally active and potent noncovalent modulator of sickled hemoglobin (HbS), specifically binds to Hb with nanomolar affinity and demonstrates</p>Fórmula:C19H16FN5O2Forma y color:SolidPeso molecular:365.36Sezolamide
CAS:<p>Sezolamide is a carbonic anhydrase inhibitor.</p>Fórmula:C11H18N2O4S3Forma y color:SolidPeso molecular:338.47Bcl-2-IN-11
CAS:<p>Bcl-2-IN-11 (compound 6) is a potent and selective inhibitor of Bcl-2 activity, exhibiting an IC50 of 0.9 nM, and demonstrates minimal inhibition against Bcl-xl</p>Fórmula:C45H49ClFN7O8SForma y color:SolidPeso molecular:902.43Dibenamine hydrochloride
CAS:<p>Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.</p>Fórmula:C16H19Cl2NPureza:96.43%Forma y color:Oily Liquid SolidPeso molecular:296.23Falcarindiol
CAS:<p>Falcarindiol: Activates PPARγ, boosts ABCA1, induces apoptosis/autophagy, has anti-inflammatory/anticancer effects.</p>Fórmula:C17H24O2Forma y color:SolidPeso molecular:260.37Indacrinone
CAS:<p>Indacrinone is an investigational diuretic.</p>Fórmula:C18H14Cl2O4Pureza:98%Forma y color:SolidPeso molecular:365.21SN38-COOH
CAS:<p>SN38-COOH, the active metabolite of the topoisomerase I inhibitor irinotecan, is utilized in the synthesis of antibody-drug conjugates (ADCs).</p>Fórmula:C26H24N2O8Forma y color:SolidPeso molecular:492.48ICI-M247496
CAS:<p>ICI-M247496 is a non-polyglutamated analog of CB3717 and quinazoline-based inhibitor of thymidylate synthase.</p>Fórmula:C19H16N4O3Forma y color:SolidPeso molecular:348.361-Methoxyphaseollidin
CAS:1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.Fórmula:C21H22O5Pureza:98%Forma y color:SolidPeso molecular:354.4JBI-589
CAS:<p>JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis.</p>Fórmula:C29H28FN5OForma y color:SolidPeso molecular:481.56Trk-IN-10
CAS:<p>Trk-IN-10 inhibits TRK (IC50: 0.86 nM TrkA, 6.92 nM TrkA G595R, 350 nM ALK), promising for solid tumors with selective action and potential lower toxicity.</p>Fórmula:C20H20FN5O3Forma y color:SolidPeso molecular:397.4ACT-606559
<p>ACT-606559, a metabolite of ACT451840, is a novel chemical compound exhibiting antimalarial properties. It is utilized in malaria research.</p>Fórmula:C47H52N6O3Forma y color:SolidPeso molecular:748.95Oxamniquine
CAS:<p>Oxamniquine is an effective compound for the treatment of schistosomiasis.</p>Fórmula:C14H21N3O3Pureza:98%Forma y color:Pale Yellow Crystals From Isopropanol SolidPeso molecular:279.33GLX481304
CAS:<p>GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.</p>Fórmula:C23H29N7OForma y color:SolidPeso molecular:419.52ZK824190
CAS:<p>ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.</p>Fórmula:C22H20F2N2O4Pureza:98.84%Forma y color:SolidPeso molecular:414.44-(3,4-Difluorobenzo)curcumin
CAS:<p>4-(3,4-Difluorobenzo)curcumin (CDF) is a semisynthetic coumarin noted for its antiparasitic and anticancer properties.</p>Fórmula:C28H22F2O6Forma y color:SolidPeso molecular:492.50Antifungal agent 24
CAS:<p>Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).</p>Fórmula:C24H18F2N4OForma y color:SolidPeso molecular:416.42RP-001
CAS:<p>RP-001 is a selective agonist of picomolar short-acting S1P1 (EDG1)(EC50 of 9 pM), has little activity on S1P2-S1P4 and only moderate affinity for S1P5.</p>Fórmula:C24H24N4O4Pureza:98%Forma y color:SolidPeso molecular:432.47THR-β modulator-1
CAS:<p>THR-β Modulator-1 (Compound 1a) is a potent modulator of the thyroid hormone receptor β, utilized in the study of thyroid hormone receptor-associated disorders</p>Fórmula:C17H14Cl2N6O4Forma y color:SolidPeso molecular:437.24Naltiazem
CAS:<p>Naltiazem, a calcium channel antagonist, is used potentially for the treatment of arrhythmias, hypertension and myocardial infarction.</p>Fórmula:C26H28N2O4SPureza:98%Forma y color:SolidPeso molecular:464.58Biphenylindanone A
CAS:<p>Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.</p>Fórmula:C30H30O4Pureza:98%Forma y color:SolidPeso molecular:454.56RORγt Inverse agonist 3
CAS:<p>RORγt Inverse agonist 3 is a potent, selective and orally active inverse agonist of RORγ(EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells),</p>Fórmula:C29H31Cl2N5O4SPureza:98%Forma y color:SolidPeso molecular:616.56THRβ receptor agonist-1
CAS:<p>THRβ receptor agonist-1 is an agonist for the THRβ receptor [1].</p>Fórmula:C18H12Cl2N6O4Forma y color:SolidPeso molecular:447.23D-threo-PDMP
CAS:<p>D-threo-PDMP inhibits glucoceramide synthase, cutting cell surface glycosphingolipids and hindering neurite growth.</p>Fórmula:C23H38N2O3Forma y color:SolidPeso molecular:390.56CXCR2 antagonist 2
CAS:<p>CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunotherapy with an IC 50 value of 95 nM.</p>Fórmula:C17H17FN2O4SForma y color:SolidPeso molecular:364.39JA-ACC
CAS:<p>Jasmonyl-ACC (JA-ACC), a derivative of 1-aminocyclopropane-1-carboxylic acid (ACC)—the direct precursor to ethylene—impedes root growth in Arabidopsis, with</p>Fórmula:C16H23NO4Forma y color:SolidPeso molecular:293.36NIR-H2O2
<p>NIR-H2O2: Cell-permeable, NIR fluorescent sensor; activates with H2O2 for clear NIR signal.</p>Fórmula:C34H33BClNO4Pureza:98%Forma y color:SolidPeso molecular:565.89Ro 41-5253
CAS:<p>Ro 41-5253 is a RARα antagonist with antitumor activity that inhibits the proliferation of ZR-75.1 estrogen receptor-positive breast cancer cells.</p>Fórmula:C28H36O5SPureza:98%Forma y color:SolidPeso molecular:484.65BMS-262084
CAS:<p>BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.</p>Fórmula:C18H31N7O5Forma y color:SolidPeso molecular:425.48
