Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.519 productos)
- Apoptosis(5.787 productos)
- Ciclo celular / Checkpoint(4.446 productos)
- Cromatina / Epigenética(2.235 productos)
- Señalización citoesquelética(1.381 productos)
- Daño al ADN / Reparación del ADN(2.824 productos)
- Endocrinología / Hormonas(3.500 productos)
- Enzima(3.639 productos)
- GPCR / proteína G(8.317 productos)
- Inmunología e inflamación(3.516 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(404 productos)
- Señalización MAPK(1.200 productos)
- Transportador de membrana / canal de iones(2.787 productos)
- Metabolismo(9.416 productos)
- Microbiología / Virología(6.968 productos)
- Neurociencia(9.919 productos)
- Otros inhibidores(37.928 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.400 productos)
- Proteasas / Proteasoma(1.596 productos)
- Células madre y Derivados(831 productos)
- Tirosina quinasa / adaptadores(2.015 productos)
- Ubiquitinación(1.649 productos)
Mostrar 16 subcategorías más
Se han encontrado 66626 productos de "Inhibidores"
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ICMT-IN-43
CAS:<p>ICMT-IN-43 (compound 22) acts as a potent inhibitor of the enzyme ICMT, exhibiting an inhibitory concentration (IC50) value of 0.04 μM [1].</p>Fórmula:C23H31NOForma y color:SolidPeso molecular:337.5Vedaclidine tartrate
CAS:<p>Vedaclidine tartrate is a muscarinic analgesic.</p>Fórmula:C17H27N3O6S2Pureza:98%Forma y color:SolidPeso molecular:433.54ATAC21
CAS:<p>ATAC21 is a linker-immune-stimulatory compound created by conjugating a noncleavable maleimide-PEG4 linker, which includes a succinimide group, with an immune-</p>Fórmula:C38H50N12O21P2Forma y color:SolidPeso molecular:1072.82SW106
CAS:<p>SW106 blocks PTHR1 cAMP signaling, not affecting mutant PTHR1-T410P/H223R.</p>Fórmula:C16H14F5NO2Forma y color:SolidPeso molecular:347.28BChE/HDAC6-IN-1
CAS:<p>BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor that exhibits potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6.</p>Fórmula:C34H43N5O5Pureza:98%Forma y color:SolidPeso molecular:601.74ARTD3/PARP3-IN-1
CAS:<p>ARTD3/PARP3-IN-1 is a non-selective inhibitor targeting diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3)/PARP3 [1].</p>Fórmula:C17H16N4O2Forma y color:SolidPeso molecular:308.33RXPA 380
CAS:<p>RXPA 380: C-terminal ACE inhibitor, Ki=3nM; IC50=2.5nM for C-domain ACE mutants.</p>Fórmula:C33H36N3O7PForma y color:SolidPeso molecular:617.63MI-888 free base
CAS:<p>MI-888 is the most potent MDM2 inhibitor (Ki = 0.44 nM), with high oral efficacy in human cancer models and optimal pharmacokinetics.</p>Fórmula:C28H32Cl2FN3O3Forma y color:SolidPeso molecular:548.48Fiduxosin hydrochloride
CAS:<p>Fiduxosin hydrochloride is an alpha 1a-adrenoceptor antagonist that may be useful in the treatment of Benign Prostatic Hyperplasia.</p>Fórmula:C30H30ClN5O4SForma y color:SolidPeso molecular:592.11Minocromil
CAS:<p>Minocromil is a new agent of Anti-asthmatic.</p>Fórmula:C18H16N2O6Pureza:98%Forma y color:SolidPeso molecular:356.33RXFP1 receptor agonist-6
CAS:<p>RXFP1 receptor agonist-6 (Example 7) serves as an agonist for the RXFP1 receptor and effectively suppresses cAMP production in HEK293 cells that stably express</p>Fórmula:C38H32F5N3O7Forma y color:SolidPeso molecular:737.67Trap-101 hydrochloride
CAS:<p>nociceptin/orphanin FQ (NOP) receptor antagonist</p>Fórmula:C24H36ClN3O2Pureza:98%Forma y color:SolidPeso molecular:434.02BACE-1 inhibitor 1
CAS:<p>BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).</p>Fórmula:C17H14BrF3N4O2Pureza:98%Forma y color:SolidPeso molecular:443.22Amikhellin HCl
CAS:<p>Amikhellin HCl, a synthetic antimitotic and vasodilator, is water-soluble, derived from Ammi Visnaga, and inhibits DNA polymerase in leukemia.</p>Fórmula:C18H22ClNO5Forma y color:SolidPeso molecular:367.82RO5527239
CAS:<p>RO5527239 is a potent, orally available GPBAR1 agonist agent.</p>Fórmula:C28H31N3O3Pureza:98%Forma y color:SolidPeso molecular:457.56P-1075
CAS:<p>P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.</p>Fórmula:C12H17N5Pureza:99.85%Forma y color:SolidPeso molecular:231.3D-Ala-Lys-AMCA TFA (375822-19-8 free base)
<p>D-Ala-Lys-AMCA HCl: PEPT1 substrate, blue fluorescence, enters Caco-2/liver cancer cells.</p>Fórmula:C23H29F3N4O8Pureza:98%Forma y color:SolidPeso molecular:546.49(S,R)-WT IDH1 Inhibitor 2
CAS:<p>(S,R)-WT IDH1 Inhibitor 2: selectively targets mutant IDH1; IC50 - R132G: 2.9 nM, R132C: 3.8 nM, R132H: 4.6 nM, WT: 46 nM; potential for AML treatment.</p>Fórmula:C28H28FN5O3Forma y color:SolidPeso molecular:501.55(Z)-KC02
CAS:<p>(Z)-KC02 is an ABHD16A inhibitor which targets the enzyme responsible for producing lysophosphatidylserine (lyso-PS), a lipid involved in regulating immune and</p>Fórmula:C17H21NO3Forma y color:SolidPeso molecular:287.35STING-IN-7
CAS:<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Fórmula:C16H14ClN3OPureza:98%Forma y color:SolidPeso molecular:299.76MAO A/HSP90-IN-2
CAS:<p>MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90.</p>Fórmula:C25H31ClN2O4Pureza:98%Forma y color:SolidPeso molecular:458.98AZD1092
CAS:<p>AZD1092 is the glucokinase enzyme activator.</p>Fórmula:C24H26N4O5Pureza:98%Forma y color:SolidPeso molecular:450.49PSMA-Val-Cit-PAB-MMAE
CAS:<p>PSMA-Val-Cit-PAB-MMAE is a novel PSMA-targeted small-molecule conjugate leveraging monomethyl auristatin E (MMAE) for prostate cancer chemotherapy.</p>Fórmula:C114H165ClN20O26Forma y color:SolidPeso molecular:2267.15-DACTHF
CAS:<p>5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.</p>Fórmula:C19H24N6O6Pureza:98%Forma y color:SolidPeso molecular:432.43HPK1-IN-37
CAS:<p>HPK1-IN-37 (compound A85), with an IC50 value of 3.7 nM, is a potent inhibitor of HPK1.</p>Fórmula:C27H35N7O4Forma y color:SolidPeso molecular:521.61Orexin receptor modulator-1
CAS:<p>Orexin Receptor Modulator-1 is a compound utilized in the study of various conditions including substance addiction, panic disorder, anxiety, post-traumatic</p>Fórmula:C23H22ClF5N6OForma y color:SolidPeso molecular:528.91Thymidine-5'-O-(α,β-methylene)diphosphate sodium
CAS:<p>Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM).</p>Fórmula:C11H15N2O10P2·3NaForma y color:SolidPeso molecular:466.16CJ-12255
CAS:<p>CJ-12255 is a Neurokinin-1 Receptor Antagonist.</p>Fórmula:C32H38N2O3Forma y color:SolidPeso molecular:498.66DT-061
CAS:<p>DT-061 is an orally bioavailable protein phosphatase 2A (PP2A) activator. It could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.</p>Fórmula:C25H23F3N2O5SPureza:98%Forma y color:SolidPeso molecular:520.52Alteconazole
CAS:<p>Alteconazole is an antifungal drug.</p>Fórmula:C17H12Cl3N3OPureza:98%Forma y color:SolidPeso molecular:380.66SIRT6-IN-3
CAS:<p>SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts</p>Fórmula:C21H30Br3ClN6SPureza:98%Forma y color:SolidPeso molecular:673.73SCH 206272
CAS:<p>SCH 206272 is a potent, orally active antagonist of tachykinin NK(1), NK(2), and NK(3) receptor.</p>Fórmula:C33H41Cl4N5O4Forma y color:SolidPeso molecular:713.52XIE62-1004
CAS:<p>XIE62-1004 is a chemical compound that induces the interaction between p62 and LC3 by binding to the ZZ domain of p62.</p>Fórmula:C23H25NO3·HClForma y color:SolidPeso molecular:399.91Immunosuppressant-1
CAS:<p>Immunosuppressant-1 (Compound 31) suppresses T-cell proliferation triggered by anti-CD3/anti-CD28 co-stimulation and demonstrates immunosuppressive effects,</p>Fórmula:C14H12BrNO3Pureza:98%Forma y color:SolidPeso molecular:322.15USP1-IN-5
CAS:<p>USP1-IN-5 (compound 10) is a potent inhibitor of both USP1, with an IC50 of less than 50 nM, and MDA-MB-436 cells, where it also exhibits an IC50 of less than</p>Fórmula:C27H23F3N8OForma y color:SolidPeso molecular:532.52Cintirorgon sodium
CAS:<p>Cintirorgon (LYC-55716) is an oral RORgamma agonist with immunomodulatory and anticancer effects.</p>Fórmula:C27H23F6NNaO6SPureza:98%Forma y color:SolidPeso molecular:626.52Benzyl-α-GalNAc
CAS:<p>Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces.</p>Fórmula:C15H21NO6Pureza:99.84%Forma y color:SolidPeso molecular:311.33GSK3491943
CAS:<p>GSK3491943 is a potent TRPV4 inhibitor with IC50 = 3.2 nM. GSK3491943 is a potential agent for the treatment of heart failure and respiratory diseases.</p>Fórmula:C18H16Cl2N2O5SForma y color:SolidPeso molecular:443.3ATM-IN-1
CAS:<p>ATM-IN-1 is a potent inhibitor of ATM. ATM-IN-1 has shown research potential in cancer and neurological diseases.</p>Fórmula:C30H36N6O3Forma y color:SolidPeso molecular:528.65EP4 receptor antagonist 1
CAS:<p>EP4 antagonist 1: inhibits human/mouse EP4 receptors (IC50: 6.1/16.2 nM), selective over EP1-EP3 (>10 μM). For cancer immunotherapy.</p>Fórmula:C23H21F3N4O3Pureza:99.53%Forma y color:SolidPeso molecular:458.43WRN inhibitor 2
CAS:<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Fórmula:C15H11F3N2O5S2Pureza:98%Forma y color:SolidPeso molecular:420.38TIE-2/VEGFR-2 kinase-IN-4
CAS:<p>TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, serves as a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, exhibiting inhibitory</p>Fórmula:C26H17F4N5O4Forma y color:SolidPeso molecular:539.44T-448 free base
CAS:<p>T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).</p>Fórmula:C17H20N4OSPureza:98%Forma y color:SolidPeso molecular:328.43Antitumor agent-120
CAS:<p>Antitumor agent-120 (compound 1), a flavonoid derived from Kudzu root, exhibits negligible inhibitory effects on LNCaP and PC3 cancer cells, with IC50 values</p>Fórmula:C17H16N2O3Forma y color:SolidPeso molecular:296.32Z-LLY-FMK
CAS:<p>Z-LLY-FMK (Calpain Inhibitor IV) serves as an inhibitor of calpain, a family of proteases implicated in the apoptosis of various cell systems.</p>Fórmula:C30H40FN3O6Pureza:98%Forma y color:SolidPeso molecular:557.65ORM-13070
CAS:<p>ORM-13070 is a selective antagonist radioligand for the α2C adrenoceptor subtype. ORM-13070 C-11 is under investigation in clinical trial.</p>Fórmula:C20H25N3O3Forma y color:SolidPeso molecular:355.43ES 8891
CAS:<p>ES 8891 is an inhibitor of renin.</p>Fórmula:C42H60N6O6SPureza:98%Forma y color:SolidPeso molecular:777.03HIF-2α-IN-9
CAS:<p>HIF-2α-IN-9 (compound 35r) serves as an HIF-2α inhibitor, effectively suppressing VEGF-A with an IC50 of 305 nM, and modulating growth-promoting genes within</p>Fórmula:C12H13F5O4S2Pureza:98%Forma y color:SolidPeso molecular:380.35Droxicam
CAS:<p>Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal</p>Fórmula:C16H11N3O5SPureza:99.04%Forma y color:SolidPeso molecular:357.34Deltasonamide 1
CAS:<p>Deltasonamide is a potent and selective inhibitor of PDE6δ‐KRas.</p>Fórmula:C30H39ClN6O4S2Forma y color:SolidPeso molecular:647.25
