Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.519 productos)
- Apoptosis(5.787 productos)
- Ciclo celular / Checkpoint(4.446 productos)
- Cromatina / Epigenética(2.235 productos)
- Señalización citoesquelética(1.381 productos)
- Daño al ADN / Reparación del ADN(2.824 productos)
- Endocrinología / Hormonas(3.500 productos)
- Enzima(3.639 productos)
- GPCR / proteína G(8.317 productos)
- Inmunología e inflamación(3.516 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(404 productos)
- Señalización MAPK(1.200 productos)
- Transportador de membrana / canal de iones(2.787 productos)
- Metabolismo(9.416 productos)
- Microbiología / Virología(6.968 productos)
- Neurociencia(9.919 productos)
- Otros inhibidores(37.928 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.400 productos)
- Proteasas / Proteasoma(1.596 productos)
- Células madre y Derivados(831 productos)
- Tirosina quinasa / adaptadores(2.015 productos)
- Ubiquitinación(1.649 productos)
Mostrar 16 subcategorías más
Se han encontrado 66626 productos de "Inhibidores"
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MurA-IN-4
CAS:<p>MurA-IN-4 exhibits antibacterial properties as a MurA inhibitor, impeding the synthesis of bacterial cell walls [1].</p>Fórmula:C8H12ClNO3Forma y color:SolidPeso molecular:205.64ToP-DNJ
CAS:<p>ToP-DNJ is a selective inhibitor of endoplasmic reticulum α-Glucosidase II, exhibiting antiflaviviral activity.</p>Fórmula:C40H71NO6Forma y color:SolidPeso molecular:661.99Carbonic anhydrase inhibitor 12
CAS:<p>CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.</p>Fórmula:C27H22BrN5O5S2Pureza:98%Forma y color:SolidPeso molecular:640.53Amelparib
CAS:<p>Amelparib (JPI-289) is an inhibitor of the poly-ADP-ribose polymerase.</p>Fórmula:C19H25N3O3Pureza:98%Forma y color:SolidPeso molecular:343.42YM348
CAS:<p>YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).</p>Fórmula:C14H17N3OPureza:98%Forma y color:SolidPeso molecular:243.3(Rac)-Modipafant
CAS:<p>(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.</p>Fórmula:C34H29ClN6O3Pureza:97.96% - 98.09%Forma y color:SolidPeso molecular:605.09VU0364739
CAS:<p>VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].</p>Fórmula:C26H27FN4O2Pureza:98%Forma y color:SolidPeso molecular:446.52SQ 32970
CAS:<p>SQ 32970 is a potent Endothia aspartic proteinase inhibitor.</p>Fórmula:C33H51N5O4SForma y color:SolidPeso molecular:613.85Vipoglanstat
CAS:<p>Vipoglanstat: inhibits prostaglandin E synthase, anti-inflammatory, reduces leukocyte infiltration and lung injury from endotoxin/sepsis.</p>Fórmula:C30H34Cl2F5N5O3Forma y color:SolidPeso molecular:678.52Biphenylindanone A
CAS:<p>Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.</p>Fórmula:C30H30O4Pureza:98%Forma y color:SolidPeso molecular:454.56CMB-087229
CAS:<p>CMB-087229 is an inhibitor of mutant superoxide dismutase 1 (SOD1) protein aggregation, exhibiting an IC50 of 67 nM, and holds potential for use in amyotrophic</p>Fórmula:C10H8Cl2N2O2Forma y color:SolidPeso molecular:259.095-HT2A antagonist 1
CAS:<p>5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.</p>Fórmula:C26H28N4O2Pureza:98%Forma y color:SolidPeso molecular:428.53WAY-620445
CAS:<p>WAY-620445 is an active molecule.</p>Fórmula:C19H17NO4S2Forma y color:SolidPeso molecular:387.47Mezigdomide
CAS:<p>Mezigdomide (CC-92480) is a potent, novel cereblon E3 ubiquitin ligase modulator (CELMoD) that acts as a molecular glue.Cost-effective and quality-assured.</p>Fórmula:C32H30FN5O4Pureza:97.21% - 99.68%Forma y color:SolidPeso molecular:567.61PKC-θ inhibitor 1
CAS:<p>PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)</p>Fórmula:C17H15F3N4OPureza:98%Forma y color:SolidPeso molecular:348.32Cbl-b-IN-7
CAS:<p>Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s</p>Fórmula:C29H31F4N5O2Pureza:98%Forma y color:SolidPeso molecular:557.58GGTI2417
CAS:<p>GGTI2417 blocks Geranylgeranyltransferase I, targeting RalB for apoptosis and RalA to stop growth.</p>Fórmula:C24H33N5O4Forma y color:SolidPeso molecular:455.55TRPC5-IN-3
CAS:<p>TRPC5-IN-3 is a potent TRPC5 inhibitor (IC50= 10.75 nM).</p>Fórmula:C18H15ClF3N5OForma y color:SolidPeso molecular:409.79GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Fórmula:C21H24F3N7OPureza:99.86% - 99.86%Forma y color:SolidPeso molecular:447.46Gusperimus trihydrochloride
CAS:<p>Gusperimus trihydrochloride is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity.</p>Fórmula:C17H40Cl3N7O3Pureza:98%Forma y color:SolidPeso molecular:496.9VU0652925
CAS:<p>VU0652925 is a PAR4 antagonist. VU0652925 has a P-sel IC50 of 39.2 pM (-pIC50±SEM: 10.41±0.04) and a PAC1 IC50 of 43.0 pM (-pIC50±SEM: 10.4±0.04).</p>Fórmula:C24H18N4O4S2Forma y color:SolidPeso molecular:490.55AGN 210676
CAS:<p>AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).</p>Fórmula:C23H29NO5SPureza:98%Forma y color:SolidPeso molecular:431.55PF-04634817 succinate
CAS:<p>PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.</p>Fórmula:C29H42F3N5O7Pureza:98%Forma y color:SolidPeso molecular:629.67DQP-26
CAS:<p>DQP-26, a potent negative allosteric modulator of NMDA receptors (NMDARs), exhibits IC50 values of 0.77 μM for GluN2C and 0.44 μM for GluN2D subunits,</p>Fórmula:C28H21Cl2N3O4Pureza:98%Forma y color:SolidPeso molecular:534.39Licostinel
CAS:<p>Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.</p>Fórmula:C8H3Cl2N3O4Pureza:98.02%Forma y color:SolidPeso molecular:276.03LMPTP INHIBITOR 1 hydrochloride
CAS:<p>LMPTP INHIBITOR 1 hydrochloride is a selective inhibitor of low molecular weight protein tyrosine phosphatase ( LMPTP ), with an IC 50 of 0.8 μM for LMPTP-A.</p>Fórmula:C28H37ClN4OPureza:99.89%Forma y color:SolidPeso molecular:481.07ADL-08-0011
CAS:<p>ADL-08-0011 is an metabolite of alvimopan.</p>Fórmula:C23H29NO3Forma y color:SolidPeso molecular:367.49C18 Ceramide-1-phosphate (d18:1/18:0) ammonium
CAS:<p>C18 Ceramide-1-phosphate (d18:1/18:0) is a long-chain molecule identified in murine skin known to promote the migration of mouse bone marrow-derived multipotent</p>Fórmula:C36H71NO6P·NH4Forma y color:SolidPeso molecular:662.96RXFP1 receptor agonist-5
CAS:<p>RXFP1 receptor agonist-5 (Example 98) is an agonist that targets the RXFP1 receptor and demonstrates its bioactivity by inhibiting cAMP production in HEK293</p>Fórmula:C30H23F6N3O7Forma y color:SolidPeso molecular:651.51RTI-13951-33
CAS:<p>RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional assay).</p>Fórmula:C28H33N3O3Pureza:98%Forma y color:SolidPeso molecular:459.58C-6 NBD-dihydro-Ceramide
CAS:<p>C-6 NBD-dihydro-Ceramide, a biologically active, fluorescent analog of short-chain ceramides, features membrane permeability.</p>Fórmula:C30H49N5O6Forma y color:SolidPeso molecular:575.74ONO-0740556
CAS:<p>ONO-0740556 is a potent agonist of the Gi-coupled human lysophosphatidic acid receptor 1 (LPA1), exhibiting an EC50 value of 0.26 nM.</p>Fórmula:C20H34NO6PForma y color:SolidPeso molecular:415.46AMG-548 dihydrochloride (864249-60-5 free base)
<p>AMG-548 dihydrochloride: oral p38α inhibitor, Ki: 0.5 nM; less so for p38β, Ki: 36 nM; >> p38γ/δ; blocks LPS-induced TNFα, IC50: 3 nM.</p>Fórmula:C29H29Cl2N5OPureza:98%Forma y color:SolidPeso molecular:534.48A-371191
CAS:<p>A-371191 is an antagonist of Bcl-XL.</p>Fórmula:C36H47N5O5S2Pureza:98%Forma y color:SolidPeso molecular:693.92cis-ent-Tadalafil
CAS:<p>cis-ent-Tadalafil (cis-ent-IC-351) is a potent and selective PDE5 inhibitor that lowers blood pressure.</p>Fórmula:C22H19N3O4Pureza:99.86%Forma y color:SolidPeso molecular:389.4VEGFR2-IN-3
CAS:<p>VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].</p>Fórmula:C26H28ClN5O4Pureza:98%Forma y color:SolidPeso molecular:509.98GSK-2245035 maleate
CAS:<p>GSK-2245035 maleate is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties.</p>Fórmula:C24H38N6O6Forma y color:SolidPeso molecular:506.6AGN-201904Z
CAS:<p>AGN-201904Z is a slow-release, acid-resistant pro-PPI that turns into omeprazole, offering extended acid suppression.</p>Fórmula:C25H25N3NaO8S2Pureza:98%Forma y color:SolidPeso molecular:582.6Antituberculosis agent-1
CAS:<p>Antituberculosis Agent-1 (Compound 8a) is an effective antituberculosis agent, demonstrating a minimum inhibitory concentration (MIC) of 3.84 μg/mL against</p>Fórmula:C21H21NO4Forma y color:SolidPeso molecular:351.4SB-682330A
CAS:<p>SB-682330A is a Raf kinase inhibitor.</p>Fórmula:C28H27N3O3Forma y color:SolidPeso molecular:453.53MK-8666 Tris
CAS:<p>MK-8666, a partial GPCR agonist, targets GPR40 to enhance insulin secretion, potentially treating type 2 diabetes without adverse effects.</p>Fórmula:C33H42N2O9SForma y color:SolidPeso molecular:642.764Antileishmanial agent-17
CAS:<p>Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.</p>Fórmula:C27H37N5O5Pureza:98%Forma y color:SolidPeso molecular:511.61Pivanex
CAS:<p>Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.</p>Fórmula:C10H18O4Pureza:≥98%Forma y color:SolidPeso molecular:202.25NIP-101
CAS:<p>NIP-101 is a potent calcium antagonist.</p>Fórmula:C38H45N4O7PForma y color:SolidPeso molecular:700.76XRP44X
CAS:<p>XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.</p>Fórmula:C21H21ClN4OPureza:99.67%Forma y color:SolidPeso molecular:380.87RO5068760
CAS:<p>RO5068760, a selective MEK1/2 inhibitor, effectively targets a range of tumors, particularly B-RafV600E mutants, with an IC50 of 0.025 μM.</p>Fórmula:C28H27FIN3O6Forma y color:SolidPeso molecular:647.43PD 160170
CAS:<p>neuropeptide Y1 receptor antagonist</p>Fórmula:C18H17N3O4SPureza:98%Forma y color:SolidPeso molecular:371.41SARS-CoV-2-IN-69
CAS:<p>SARS-CoV-2-IN-69 (Compound 7E) is a potent, non-covalent inhibitor of the SARS-CoV-2 main protease (M^pro) with an EC50 of 7.4 μM and also inhibits the papain-</p>Fórmula:C15H11NO3SPureza:98%Forma y color:SolidPeso molecular:285.32Chroman 1
CAS:<p>Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).</p>Fórmula:C24H28N4O4Pureza:99.67% - 99.84%Forma y color:SolidPeso molecular:436.5TCS 2510
CAS:<p>TCS 2510 (CAY10598) 是一种选择性 PGE2 和 EP4 受体激动剂，可增强细胞内 cAMP 浓度和活性 β-caten 的丰度。TCS 2510 抑制TNF-α 产生，可用于研究代谢紊乱带来的疾病。</p>Fórmula:C21H29N5O2Pureza:98%Forma y color:SolidPeso molecular:383.49
