Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.797 productos)
- Apoptosis(6.275 productos)
- Ciclo celular / Checkpoint(4.805 productos)
- Cromatina / Epigenética(2.462 productos)
- Señalización citoesquelética(1.534 productos)
- Daño al ADN / Reparación del ADN(2.959 productos)
- Endocrinología / Hormonas(3.708 productos)
- Enzima(3.670 productos)
- GPCR / proteína G(9.020 productos)
- Inmunología e inflamación(3.884 productos)
- Virus de la gripe(301 productos)
- Señalización JAK / STAT(414 productos)
- Señalización MAPK(1.249 productos)
- Transportador de membrana / canal de iones(3.050 productos)
- Metabolismo(10.206 productos)
- Microbiología / Virología(7.612 productos)
- Neurociencia(10.379 productos)
- Otros inhibidores(36.012 productos)
- Reducción de oxidación(42 productos)
- Señalización PI3K / Akt / mTOR(1.442 productos)
- Proteasas / Proteasoma(1.724 productos)
- Células madre y Derivados(819 productos)
- Tirosina quinasa / adaptadores(2.035 productos)
- Ubiquitinación(1.718 productos)
Mostrar 16 subcategorías más
Se han encontrado 66683 productos de "Inhibidores"
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GDC-0349
CAS:GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.Fórmula:C24H32N6O3Pureza:96.00% - 98.49%Forma y color:SolidPeso molecular:452.55EGFR-IN-8
CAS:<p>EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLC</p>Fórmula:C32H23ClF3N7O4Pureza:99.51%Forma y color:SolidPeso molecular:662.02HM43239
CAS:HM43239: oral FLT3 inhibitor; IC50: FLT3 WT 1.1nM, ITD 1.8nM, D835Y 1.0nM; blocks p-STAT5/p-ERK; affects SYK, JAK1/2, TAK1; halts leukemia cell growth.Fórmula:C29H33ClN6Pureza:99.7%Forma y color:SolidPeso molecular:501.07Ref: TM-T9428
1mg49,00€5mg104,00€10mg166,00€25mg325,00€50mg490,00€100mg682,00€200mg903,00€1mL*10mM (DMSO)115,00€Mutant IDH1-IN-2
CAS:Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of ＜22 nM in LS-Fórmula:C24H31F2N5O2Pureza:99.88%Forma y color:SolidPeso molecular:459.53Ref: TM-T12128
1mg64,00€5mg145,00€10mg235,00€25mg394,00€50mg562,00€100mg758,00€200mg1.017,00€1mL*10mM (DMSO)144,00€PXS-5120A
CAS:PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.Fórmula:C22H25ClFN3O4SPureza:97.02%Forma y color:SolidPeso molecular:481.97Ref: TM-T12584
1mg216,00€2mg309,00€5mg487,00€10mg645,00€25mg944,00€50mg1.293,00€100mg1.730,00€1mL*10mM (DMSO)530,00€AZ-23
CAS:AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C.Fórmula:C17H19ClFN7OPureza:99.4%Forma y color:SolidPeso molecular:391.83PKC-IN-1
CAS:PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6,Fórmula:C25H37FN8O2Pureza:98% - 98.79%Forma y color:SolidPeso molecular:500.61CAY10781
CAS:CAY10781 inhibits NRP-1/VEGF-A binding by 43% at 12.5μM and blocks VEGFR2 phosphorylation in CAD cells.Fórmula:C11H9N3O3Pureza:99.49%Forma y color:SolidPeso molecular:231.21Ref: TM-T37424
2mg42,00€5mg57,00€10mg81,00€25mg131,00€50mg180,00€100mg334,00€200mg467,00€1mL*10mM (DMSO)84,00€Src Inhibitor 3
CAS:Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.Fórmula:C34H32ClFN8O4Pureza:98.35%Forma y color:SolidPeso molecular:671.12Ref: TM-T13000
1mg92,00€5mg187,00€10mg320,00€25mg507,00€50mg702,00€100mgA consultar1mL*10mM (DMSO)279,00€SR 142948
CAS:SR 142948 is a neurotensin (NT) receptor antagonist.Fórmula:C39H51N5O6Pureza:98%Forma y color:SolidPeso molecular:685.85MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Fórmula:C20H22O4Pureza:98.57%Forma y color:SolidPeso molecular:326.39SB-616234-A
CAS:SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.Fórmula:C32H36ClN5O3Pureza:99.72%Forma y color:SolidPeso molecular:574.11Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Fórmula:C24H28FN3OPureza:99.68% - 99.91%Forma y color:SolidPeso molecular:393.5Y06137
CAS:<p>Y06137, selective BET inhibitor, Kd 81 nM for BRD4(1), researched for castration-resistant prostate cancer treatment.</p>Fórmula:C27H32N4O2Pureza:99.85%Forma y color:SolidPeso molecular:444.57L-97-1
CAS:L-97-1 is an antagonist of the adenosine A1 receptor.Fórmula:C29H38N6O3Pureza:98%Forma y color:SolidPeso molecular:518.65Lp-PLA2-IN-10
Lp-PLA2-IN-10, a potent Lp-PLA2 inhibitor, may research neurodegenerative and cardiovascular diseases.Fórmula:C21H15F5N4O4Forma y color:SolidPeso molecular:482.36Moflomycin
CAS:Moflomycin is an anthracycline derivative. It exhibits a higher antileukemic activity compared to other anthracyclines.Fórmula:C25H25IO10Pureza:98%Forma y color:SolidPeso molecular:612.36HDAC2-IN-1
HDAC2-IN-1 is an oral HDAC2 inhibitor (IC50: 0.5 μM), crosses the blood-brain barrier, and inhibits HDAC1 and HDAC8.Fórmula:C22H23ClN4OSForma y color:SolidPeso molecular:426.96Acetoxycycloheximide
CAS:<p>Acetoxycycloheximide triggers TNF receptor 1, prompts apoptosis, and cytochrome c release by activating c-Jun N-terminal kinase.</p>Fórmula:C17H25NO6Forma y color:SolidPeso molecular:339.38CD73-IN-2
CD73-IN-2 is a potent inhibitor of CD73 (IC50: 0.09 nM).Fórmula:C17H25ClN5O7PForma y color:SolidPeso molecular:477.84Cap-dependent endonuclease-IN-7
CAS:Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.Fórmula:C36H28FN3O7SForma y color:SolidPeso molecular:665.69ZK-Thiazolidinone
CAS:ZK-Thiazolidinone (TAL), ATP-competitive PLK1 inhibitor, disrupts cell division processes in vitro and in vivo, targeting human/mouse tumors.Fórmula:C23H26F3N5O2SForma y color:SolidPeso molecular:493.55HDAC10-IN-2
HDAC10-IN-2, a selective HDAC10 inhibitor (IC50=20nM), modulates autophagy in FLT3-ITD+ acute myeloid leukemia.Fórmula:C19H22N2O2Forma y color:SolidPeso molecular:310.39(S)-ZG197
(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at aFórmula:C28H35F3N4O3Forma y color:SolidPeso molecular:532.6CXCR2 antagonist 7
CXCR2 antagonist 7 is a powerful blocker with IC50s: 0.044 μM for binding, 0.66 μM for calcium mobilization.Fórmula:C14H14F2N6OSForma y color:SolidPeso molecular:352.36BW-10
CAS:BW-10 potently inhibits bombesin evoked release of gastrointestinal hormones in vitro and in vivo.Fórmula:C57H72N14O8Forma y color:SolidPeso molecular:1081.27UK-370106
CAS:UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-Fórmula:C35H44N2O5Pureza:98%Forma y color:SolidPeso molecular:572.73GSK3527497 HCl
CAS:GSK3527497: potent TRPV4 inhibitor, IC50=12 nM, targets heart/respiratory issues, for oral/IV use, low-dose effective.Fórmula:C17H17Cl2FN4O4SForma y color:SolidPeso molecular:463.3054Musettamycin
CAS:Musettamycin triggers erythroid differentiation in blood cells, acts like anthracycline antibiotics, but only inhibits gram-positive bacteria.Fórmula:C36H45NO14Forma y color:SolidPeso molecular:715.74TAM&Met-IN-1
CAS:TAM&Met-IN-1 inhibits AXL, MER, TYRO3 with IC50s 6.1, 13.2, 21.6 nM, respectively, for cancer research.Fórmula:C29H27F2N7O5Forma y color:SolidPeso molecular:591.57N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Fórmula:C11H9FN4OForma y color:SolidPeso molecular:232.21Nrf2 activator-2
Compound O15, an Osthole derivative, is a potent Nrf2 agonist with an EC50 of 2.9 μM; it inhibits Keap1-Nrf2 binding and Nrf2 ubiquitination.Fórmula:C20H17BrO3Forma y color:SolidPeso molecular:385.25ONO-AE1-259 lysine
CAS:ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)Fórmula:C28H49ClN2O6Forma y color:SolidPeso molecular:545.15MDL-27788
CAS:MDL-27788 is a tricyclic inhibitor.Fórmula:C24H26N2O5SForma y color:SolidPeso molecular:454.54AChE-IN-8
AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.Fórmula:C20H22N4O2SForma y color:SolidPeso molecular:382.48IDH1 Inhibitor 1
CAS:Oral, brain-penetrant mutant IDH1 inhibitor targeting R132H/C with IC50: 0.021/0.045μM; 2.52μM for IDH1WT.Fórmula:C20H18F4N6O2Pureza:98%Forma y color:SolidPeso molecular:450.39QTX125 TFA
QTX125 TFA: Potent, selective HDAC6 inhibitor with antitumor effects.Fórmula:C25H20F3N3O7Forma y color:SolidPeso molecular:531.44PRMT5-IN-1 hydrochloride
PRMT5 IN-1 hydrochloride is a potent PRMT5 inhibitor (IC50: 11 nM), forms covalent adduct with C449, and converts to an aldehyde in vivo.Fórmula:C19H20Cl2N4O5Forma y color:SolidPeso molecular:455.29IL-17 modulator 1 disodium
CAS:Potent, orally active IL-17 Modulator 1 (disodium) from patent WO 2020127685, used in psoriasis and arthritis research.Fórmula:C28H37N6NaO6PForma y color:SolidPeso molecular:607.604Coleon-U-quinone
CAS:Coleon-U-quinone, a P-gp inhibitor, reduces cancer cell viability and enhances Doxorubicin sensitivity in resistant cells.Fórmula:C20H24O5Forma y color:SolidPeso molecular:344.4Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Fórmula:C27H21N5O2SForma y color:SolidPeso molecular:479.55Bim-IN-1
Bim-IN-1 is a potent inhibitor of Bim expression with low toxicity, Bim-IN-1 reduces Bim expression levels with little inhibition of protein kinase A.Fórmula:C19H20Cl2FNO2SForma y color:SolidPeso molecular:416.34Icariside F2
CAS:Icariside F2 modestly inhibits α-glucosidase (4.6-12%) and has antioxidant properties, plus strong NF-κB inhibition (IC50: 16.25±2.19 μM).Fórmula:C18H26O10Pureza:98%Forma y color:SolidPeso molecular:402.39LY 215840
CAS:5-HT2/5-HT7 receptor antagonistFórmula:C24H33N3O2Pureza:98%Forma y color:SolidPeso molecular:395.54D4R antagonis-2
Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.Fórmula:C21H23ClF2N2O2Forma y color:SolidPeso molecular:408.87SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFórmula:C22H20ClF3N4O2Pureza:98%Forma y color:SolidPeso molecular:464.8716,16-Dimethyl prostaglandin E2
CAS:16,16-Dimethyl prostaglandin E2 regulates hematopoietic stem cells via EP2/EP4 and Wnt, taken orally.Fórmula:C22H36O5Pureza:98%Forma y color:SolidPeso molecular:380.52SPR-00305
CAS:SPR-00305 is a novel potent inhibitor of the mvfr pathwayFórmula:C24H19ClN2O3Forma y color:SolidPeso molecular:418.87Plumbemycin A
CAS:Plumbemycin A is isolated from Streptomyces plumbeus; an L-threonine antagonist.Fórmula:C12H20N3O9PForma y color:SolidPeso molecular:381.28
