Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.801 productos)
- Apoptosis(6.278 productos)
- Ciclo celular / Checkpoint(4.814 productos)
- Cromatina / Epigenética(2.476 productos)
- Señalización citoesquelética(1.541 productos)
- Daño al ADN / Reparación del ADN(2.948 productos)
- Endocrinología / Hormonas(3.708 productos)
- Enzima(3.671 productos)
- GPCR / proteína G(9.024 productos)
- Inmunología e inflamación(3.893 productos)
- Virus de la gripe(302 productos)
- Señalización JAK / STAT(414 productos)
- Señalización MAPK(1.247 productos)
- Transportador de membrana / canal de iones(3.064 productos)
- Metabolismo(10.184 productos)
- Microbiología / Virología(7.614 productos)
- Neurociencia(10.377 productos)
- Otros inhibidores(36.011 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.441 productos)
- Proteasas / Proteasoma(1.720 productos)
- Células madre y Derivados(812 productos)
- Tirosina quinasa / adaptadores(2.031 productos)
- Ubiquitinación(1.717 productos)
Mostrar 16 subcategorías más
Se han encontrado 66673 productos de "Inhibidores"
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PRMT5-IN-1
CAS:PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for PRMT5/MEP50).Fórmula:C19H19ClN4O5Pureza:98%Forma y color:SolidPeso molecular:418.83UTPγS trisodium salt
CAS:P2Y2 and P2Y4 receptor agonistFórmula:C9H12N2Na3O14P3SPureza:98%Forma y color:SolidPeso molecular:566.15PD-149163
CAS:PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.Fórmula:C42H71N9O6Forma y color:SolidPeso molecular:798.07NDM-1 inhibitor-3
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.Fórmula:C16H12O4Pureza:99.67%Forma y color:SolidPeso molecular:268.26Ref: TM-T60454
1mg46,00€5mg87,00€10mg145,00€25mg279,00€50mg464,00€100mg677,00€500mg1.406,00€1mL*10mM (DMSO)95,00€α-Glucosidase-IN-15
α-Glucosidase-IN-15 (Compound 14B) exhibits potent inhibitory activity against α-glucosidase, with an IC50 value of 3.34 μM.Fórmula:C24H24N2SForma y color:SolidPeso molecular:372.53Tuberculosis inhibitor 4
TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.Fórmula:C23H26N2O3SForma y color:SolidPeso molecular:410.53RX 809055AX
CAS:RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.Fórmula:C29H29ClN2O4Forma y color:SolidPeso molecular:505ICA-105665
CAS:ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.Fórmula:C19H15F2N3O2Pureza:98%Forma y color:SolidPeso molecular:355.34J-104132
CAS:J-104132: potent human ETA/B antagonist; Ki: ETA=0.034nM, ETB=0.104nM; prevents ET-1 effects, ED50 i.v.=0.045mg/kg, p.o.=0.35mg/kg.Fórmula:C31H33NO7Pureza:98%Forma y color:SolidPeso molecular:531.60GSK5852
GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.Fórmula:C27H27BF2N2O6SForma y color:SolidPeso molecular:556.39Tubulin inhibitor 13
CAS:Tubulin inhibitor 13 (E27), IC50 16.1 μM, blocks tubulin polymerization, cancer cell migration, and invasion, induces apoptosis.Fórmula:C25H21N3O4Forma y color:SolidPeso molecular:427.45Leualacin
CAS:Leualacin is a novel calcium blocker from Hapsidospora irregularis.Fórmula:C31H47N3O7Pureza:98%Forma y color:SolidPeso molecular:573.72SR121566A
CAS:SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Fórmula:C20H25N5O4SPureza:98%Forma y color:SolidPeso molecular:431.51BMS-681
CAS:BMS-681 is a CCR2 antagonist blocking chemokine binding, aiding control of inflammatory and neurodegenerative diseases.Fórmula:C26H36F3N5OForma y color:SolidPeso molecular:491.59SMP-797 HCl
CAS:SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.Fórmula:C34H44ClN5O4Pureza:98%Forma y color:SolidPeso molecular:622.20Pyrromycin
CAS:Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Fórmula:C30H35NO11Forma y color:SolidPeso molecular:585.60ONO-DI-004
CAS:ONO-DI-004 is a selective EP1 Prostanoid receptor agonist.Fórmula:C24H38O6Forma y color:SolidPeso molecular:422.55AMG-369
CAS:AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Fórmula:C26H22FN3O2SPureza:98.04% - 98.92%Forma y color:SolidPeso molecular:459.54Acetylpepstatin
CAS:Acetylpepstatin is an inhibitor of HIV-1 protease, HIV-2 protease, aspartyl protease.Fórmula:C33H61N5O11Pureza:98%Forma y color:SolidPeso molecular:703.875TAS-117 hydrochloride
TAS-117 HCl: potent oral Akt inhibitor (Akt1 IC50: 4.8nM, Akt2: 1.6nM, Akt3: 44nM), boosts anti-myeloma effects, induces cell death.Fórmula:C26H25ClN4O2Forma y color:SolidPeso molecular:460.96TX2-121-1
CAS:TX2-121-1 targets HER3 for proteasome-mediated degradation to inhibit HER3-dependent signalling and growth.Fórmula:C42H52N8O3Pureza:98%Forma y color:SolidPeso molecular:716.91L 668750
CAS:L 668750 is an inhibitor of platelet-activating factor.Fórmula:C25H34O9SPureza:98%Forma y color:SolidPeso molecular:510.6LY2934747
CAS:LY2934747 is a novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo.Fórmula:C10H13NO4Forma y color:SolidPeso molecular:211.21EGFR-IN-48
EGFR-IN-48: potent EGFR inhibitor, oral, IC50: 0.193-66.7 nM, blocks EGFR mutants & BaF3/PC-9 cell proliferation.Forma y color:SolidTCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Fórmula:C24H34N4O2SForma y color:SolidPeso molecular:442.62CYP2C1/CYP2C19-IN-2
CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.Fórmula:C27H28N2O6SForma y color:SolidPeso molecular:508.59CP-199330
CAS:CP-199330: non-toxic alternative to Zafirlukast & Pranlukast, blocks cysteyl LT1 receptors.Fórmula:C28H24ClF3N2O6SForma y color:SolidPeso molecular:609.01U75302
CAS:U75302 is an antagonist of thymosin beta-4 (TB4) receptor with a Ki value of 159 nM on guinea pig lung membranes.Fórmula:C22H35NO3Pureza:98%Forma y color:Light Yellow OilPeso molecular:361.52Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Fórmula:C23H27N3O2SForma y color:SolidPeso molecular:409.54SARS-CoV-2-IN-23
SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].Fórmula:C21H22N2OForma y color:SolidPeso molecular:318.41hCAII-IN-5
CAS:hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Fórmula:C29H18N2O7Forma y color:SolidPeso molecular:506.46CDK4/6-IN-13
CAS:Compounds 10B and 10C: potent cdk4/6 inhibitors with low nM activity, great antiproliferative effects, excellent metabolism, and good pharmacokinetics.Fórmula:C25H29N7OForma y color:SolidPeso molecular:443.54Antibiotic MA 144M2
CAS:Antibiotic MA 144M2, an anthracycline glycoside, targets gram-positive bacteria and tumors, derived from Streptomyces and aclacinomycin A conversion.Fórmula:C42H55NO16Forma y color:SolidPeso molecular:829.88Lometrexol hydrate
CAS:Lometrexol hydrate, an antipurine antifolate, inhibits GARFT and purine synthesis, leading to cancer cell apoptosis without causing DNA breaks.Fórmula:C21H27N5O7Forma y color:SolidPeso molecular:461.475WQ3810 TFA
WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity ofFórmula:C24H23F6N5O5Pureza:99.52%Forma y color:SoildPeso molecular:575.46Marizomib
CAS:Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.Fórmula:C15H20ClNO4Pureza:98.03% - 99.41%Forma y color:SolidPeso molecular:313.78Keap1-Nrf2-IN-1 TFA
Keap1-Nrf2-IN-1 TFA (compound35) is a potent inhibitor (IC50: 43 nM) protecting against acetaminophen liver damage.Fórmula:C26H25F3N2O9SForma y color:SolidPeso molecular:598.54Deoxyfuconojirimycin hydrochloride
CAS:Deoxyfuconojirimycin hydrochloride acts as a specific competitive inhibitor targeting human liver α-L-fucosidase.Fórmula:C6H14ClNO3Forma y color:SolidPeso molecular:183.63ddCTP trisodium
ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.Fórmula:C9H13N3Na3O12P3Forma y color:SolidPeso molecular:517.1Resolvin E2
CAS:RvE2, a bioactive lipid from the SPM family, is made from EPA and reduces inflammatory neutrophil infiltration and helps treat NAFLD and other diseases.Fórmula:C20H30O4Forma y color:SolidPeso molecular:334.45MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Fórmula:C25H26N6O7Forma y color:SolidPeso molecular:522.51KMH-233
CAS:KMH-233 effectively blocks LAT1, inhibiting L-leucine uptake and cell growth, boosting betastatin and cisplatin efficacy at 25 μM.Fórmula:C32H25N7O5Forma y color:SolidPeso molecular:587.58RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Fórmula:C41H78N8O5Forma y color:SolidPeso molecular:763.11Aβ-IN-2
Aβ-IN-2 is a peptide inhibitor of Aβ1-42.Fórmula:C37H51NOForma y color:SolidPeso molecular:525.81MRS4458
CAS:MRS4458 is an effective inhibitor of the P2Y14 Receptor.Fórmula:C24H20F3N5O3SPureza:98%Forma y color:SolidPeso molecular:515.51EGFR/HER2/DHFR-IN-1
Potent EGFR/HER2/DHFR inhibitor for MCF-7 breast cancer; IC50: 0.153/0.108/0.291 μM; arrests G1/S phase, triggers apoptosis.Fórmula:C14H11BrN4O2SForma y color:SolidPeso molecular:379.23SP-471
SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.Fórmula:C33H26BrN5Forma y color:SolidPeso molecular:572.5MRTX-EX185
MRTX-EX185 inhibits GDP-KRAS/G12D; IC50=90 nM on G12D. It also binds GDP-HRAS.Fórmula:C33H33FN6O2Forma y color:SolidPeso molecular:564.65Pyridoxatin
CAS:Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.Fórmula:C15H21NO3Forma y color:SolidPeso molecular:263.33HCV-IN-7
CAS:HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Fórmula:C40H48N8O6SPureza:98%Forma y color:SolidPeso molecular:768.92
