Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.523 productos)
- Apoptosis(5.792 productos)
- Ciclo celular / Checkpoint(4.449 productos)
- Cromatina / Epigenética(2.238 productos)
- Señalización citoesquelética(1.383 productos)
- Daño al ADN / Reparación del ADN(2.825 productos)
- Endocrinología / Hormonas(3.507 productos)
- Enzima(3.640 productos)
- GPCR / proteína G(8.333 productos)
- Inmunología e inflamación(3.526 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(404 productos)
- Señalización MAPK(1.202 productos)
- Transportador de membrana / canal de iones(2.790 productos)
- Metabolismo(9.448 productos)
- Microbiología / Virología(6.981 productos)
- Neurociencia(9.926 productos)
- Otros inhibidores(37.926 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.400 productos)
- Proteasas / Proteasoma(1.597 productos)
- Células madre y Derivados(831 productos)
- Tirosina quinasa / adaptadores(2.016 productos)
- Ubiquitinación(1.650 productos)
Mostrar 16 subcategorías más
Se han encontrado 66641 productos de "Inhibidores"
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TP-008
CAS:<p>TGFβRI-IN-2 is a selective, potent and orally active inhibitor of (Activin-Like Kinase 5) ALK 5(pIC50 and pEC50 values of 7.6 and 6.63, respectively).</p>Fórmula:C20H15ClFN5O2Pureza:98%Forma y color:SolidPeso molecular:411.82Caspase-3-IN-1
CAS:<p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>Fórmula:C26H25N3O6SForma y color:SolidPeso molecular:507.56Noremopamil
CAS:<p>Noremopamil is a calcium entry blocker, also being used as the precursor for radiolabelling emopamil.</p>Fórmula:C22H28N2Forma y color:SolidPeso molecular:320.47Embramine
CAS:<p>Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine.</p>Fórmula:C18H22BrNOPureza:98%Forma y color:SolidPeso molecular:348.28DPTA NONOate
CAS:<p>DPTA NONOate releases 2 NO/mole, with a 3h half-life at 37°C and 5h at 22-25°C, pH 7.4.</p>Fórmula:C6H17N5O2Forma y color:SolidPeso molecular:191.23MK-0359
CAS:<p>MK-0359 (L454560) is a selective and effective oral PDE4 inhibitor for the treatment of chronic asthma.</p>Fórmula:C31H29N3O5S2Forma y color:SolidPeso molecular:587.71Tenofovir exalidex
CAS:<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Fórmula:C28H52N5O5PPureza:99.83%Forma y color:SolidPeso molecular:569.72Tubulin polymerization-IN-10
CAS:<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Fórmula:C18H21NO6SForma y color:SolidPeso molecular:379.43DC_C66
CAS:<p>DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.</p>Fórmula:C28H22NO2Pureza:98%Forma y color:SolidPeso molecular:404.48CAY10485
CAS:<p>CAY10485 blocks human ACAT-1 & ACAT-2 (IC50: 95 & 81 μM) and hinders oxidation of LDL by 91% at 2 μM, possibly impacting atherosclerosis development.</p>Fórmula:C27H27NO7Forma y color:SolidPeso molecular:477.51Metyrapol
CAS:<p>Metyrapol is a competitive inhibitor of 11-deoxycorticosterone hydroxylation by 11β-hydroxylase.</p>Fórmula:C14H16N2OForma y color:SolidPeso molecular:228.29MC-DOXHZN hydrochloride
CAS:<p>MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin. Doxorubicin is a DNA topoisomerase II inhibitor.</p>Fórmula:C37H43ClN4O13Pureza:98%Forma y color:SolidPeso molecular:787.22AP-521 (Free base)
CAS:<p>AP-521, a 5-HT1A receptor antagonist, is used potentially for the treatment of anxiety.</p>Fórmula:C20H18N2O3SForma y color:SolidPeso molecular:366.43LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Fórmula:C15H11FN4OSPureza:98%Forma y color:SolidPeso molecular:314.34Indanazoline
CAS:<p>Indanazoline is characterized by a pronounced vasoconstrictive action.</p>Fórmula:C12H15N3Pureza:98%Forma y color:SolidPeso molecular:201.27Norbinaltorphimine
CAS:<p>nor-Binaltorphimine dihydrochloride is a long-acting potent and highly selective kappa opioid receptor antagonist.</p>Fórmula:C40H43N3O6Forma y color:SolidPeso molecular:661.79Dilopetine Citrate
CAS:<p>Dilopetine Citrate, a tachykinin receptor modulator and a neurokinin receptor modulator, is used potentially for the treatment of depression.</p>Fórmula:C19H27N3O8SForma y color:SolidPeso molecular:457.5BL-1021
CAS:<p>BL-1021, an adrenergic receptor antagonist, is used potentially for the treatment of neuropathic pain.</p>Fórmula:C23H29ClN2OForma y color:SolidPeso molecular:384.94Vitacoxib
CAS:<p>Vitacoxib is a selective inhibitor of COX-2. It is used as a novel nonsteroidal anti-inflammatory agent.</p>Fórmula:C16H14ClN3O2SPureza:98%Forma y color:SolidPeso molecular:347.82Penclomedine
CAS:<p>Penclomedine is an antineoplastic agent which alkylates and crosslinks DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis.</p>Fórmula:C8H6Cl5NO2Forma y color:SolidPeso molecular:325.4UCM 707
CAS:<p>endocannabinoid transport inhibitor</p>Fórmula:C25H37NO2Pureza:98%Forma y color:SolidPeso molecular:383.57RS-104966
CAS:<p>RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.</p>Fórmula:C19H21NO6SPureza:98%Forma y color:SolidPeso molecular:391.44CL-278474
CAS:<p>CL-278474 (compound I-79) is a potent inhibitor of β-N-acetylhexosaminidase OfHex1. CL-278474 can be used in control of insect.</p>Fórmula:C16H21N3OSPureza:99.9%Forma y color:SolidPeso molecular:303.42LX-4
CAS:<p>LX-4 activates the p38 MAPK pathway and lifts repression from certain DNA-methylated genes.</p>Fórmula:C29H19N5O4S2Forma y color:SolidPeso molecular:565.62Lergotrile mesylate
CAS:<p>Lergotrile mesylate, an ergoline derivative, suppresses prolactin in vivo and in vitro.</p>Fórmula:C18H22ClN3O3SForma y color:SolidPeso molecular:395.9Pterosin B
CAS:<p>Pterosin B, which is widely found in the leaves and shoots of green plants, is an inhibitor of salt-inducible kinase 3 (Sik3) signaling.</p>Fórmula:C14H18O2Pureza:98%Forma y color:SolidPeso molecular:218.29MLT-747
CAS:<p>MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).</p>Fórmula:C20H21Cl2N7O3Forma y color:SolidPeso molecular:478.335'-(N-Cyclopropyl)carboxamidoadenosine
CAS:<p>adenosine A2 receptor agonist</p>Fórmula:C13H16N6O4Pureza:98%Forma y color:SolidPeso molecular:320.3AH-9700 free base
CAS:<p>AH-9700 treats urge incontinence and frequent urination, binds well to sigma receptors, and increases bladder capacity in animals.</p>Fórmula:C18H25NForma y color:SolidPeso molecular:255.4(R,R)-THC
CAS:<p>agonist at ERα receptor and antagonist at ERβ receptor</p>Fórmula:C22H24O2Pureza:98%Forma y color:SolidPeso molecular:320.42Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Fórmula:C32H36N10O2Pureza:98%Forma y color:SolidPeso molecular:592.69Cevipabulin
CAS:<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Fórmula:C18H18ClF5N6OPureza:99.53%Forma y color:SolidPeso molecular:464.82CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Fórmula:C16H12N2O4S3Pureza:98%Forma y color:SolidPeso molecular:392.47PF-03463275
CAS:<p>PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS</p>Fórmula:C19H22ClFN4OPureza:99.86%Forma y color:SolidPeso molecular:376.86Rivanicline oxalate
CAS:<p>Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).</p>Fórmula:C12H16N2O4Pureza:98%Forma y color:SolidPeso molecular:252.27JFD00244
CAS:<p>JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.</p>Fórmula:C30H26N2O4Pureza:98%Forma y color:SolidPeso molecular:478.54Jimenezin
CAS:<p>Jimenezin: An annonaceous acetogenin with THF/THP, weakly acidic, insoluble, found in fruits, alcoholic drinks, and Rollinia mucosa seeds.</p>Fórmula:C37H66O7Forma y color:SolidPeso molecular:622.92Bulaquine
CAS:<p>Bulaquine, a 8-aminoquinoline derivative, targets liver stage of P. falciparum and dormant P. vivax/ovale.</p>Fórmula:C21H27N3O3Forma y color:SolidPeso molecular:369.46DR-4004
CAS:<p>DR-4004 is a selective serotonin 5-HT7 receptor antagonist.</p>Fórmula:C26H30N2OForma y color:SolidPeso molecular:386.53ZYJ-25e
CAS:<p>ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.</p>Fórmula:C30H40N4O8Pureza:98%Forma y color:SolidPeso molecular:584.66DBPR112
CAS:<p>DBPR112: oral furanopyrimidine EGFR inhibitor; IC50: 15 nM (EGFRWT), 48 nM (L858R/T790M); blocks ATP site, strong antitumor effects.</p>Fórmula:C32H31N5O3Pureza:99.25%Forma y color:SolidPeso molecular:533.62Taribavirin
CAS:<p>Taribavirin: oral drug targeting HCV in liver, spares RBCs to reduce risk of anemia.</p>Fórmula:C8H13N5O4Pureza:98%Forma y color:SolidPeso molecular:243.22GLPG2451
CAS:<p>GLPG2451 potentiates F508del CFTR at low temp (EC50: 11.1 nM), aiding cystic fibrosis treatment.</p>Fórmula:C16H16F3N3O5SForma y color:SolidPeso molecular:419.38NMS-859
CAS:<p>NMS-859 is a covalent VCP/p97 inhibitor with IC50 of 0.37 μM (60 μM ATP) and 0.36 μM (1 mM ATP).</p>Fórmula:C15H12ClN3O3SPureza:98.20%Forma y color:SolidPeso molecular:349.79Pivalopril
CAS:<p>Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.</p>Fórmula:C16H27NO4SPureza:98%Forma y color:SolidPeso molecular:329.45PhiKan 083 hydrochloride
CAS:<p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>Fórmula:C16H19ClN2Pureza:98%Forma y color:SolidPeso molecular:274.79SHIP-2a
CAS:<p>SHIP-2a is a cystathione γ lyase (CSE) inhibitor with IC50 value of 6.3 μM.</p>Fórmula:C7H8N2O2SForma y color:SolidPeso molecular:184.22FC131
CAS:<p>CXCR4 antagonist</p>Fórmula:C36H47N11O6Pureza:98%Forma y color:SolidPeso molecular:729.83Etilevodopa
CAS:<p>Etilevodopa is a prodrug for Parkinson's, rapidly becoming Levodopa and ethanol in the gut.</p>Fórmula:C11H15NO4Pureza:98%Forma y color:SolidPeso molecular:225.24Erteberel
CAS:<p>Erteberel (LY500307) is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2.</p>Fórmula:C18H18O3Pureza:99.46%Forma y color:SolidPeso molecular:282.33
