Inhibidores

Kbz probe 1, an adaptable probe utilized for examining histone benzoylation and interactions within living cells, showcases extensive versatility.

Elamipretide TFA (RX-31 TFA) is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide[1].

GEM-5, a gemcitabine conjugate with HIF-1α inhibitor YC-1 (IC50=30 nM), down-regulates HIF-1α, up-regulates p53, and induces A2780 cell apoptosis.

TLQP-21 TFA （TLQP-21 Trifluoroacetate） 是一种 VGF 衍生肽，可通过结合后折叠机制激活C3aR1 受体。

Questiomycin A derivatives 12 is a Questiomycin A derivative.

mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and metabolism, with implications in various diseases

Mouse IgG3 kappa Isotype Control is a monoclonal antibody serving as an isotype control specifically for mouse IgG3κ antibodies.

Antiviral agent 8, surpassing lead compounds crocin-1 and crocin-2, has been identified as a potent and promising candidate with enhanced antiviral activities.

Questiomycin A derivatives 14 is a Questiomycin A derivative.

Mitoquinone is a TPP-based, mitochondrially targeted antioxidant .

ER degrader 2: Potent estrogen receptor disruptor; key for cancer research.

PROTAC PARP/EGFR ligand 1 enables dual PARP EGFR degrader synthesis via PROTAC.

Nutlin carboxylic acid is a Nutlin 3-based MDM2 ligand; used with a linker to create PROTACs.

SK-575-NEG is a methylated form of SK-575, binds PARP1 (IC50: 2.64 nM), but doesn't induce PARP1 degradation up to 1 μM in cells.

PROTAC MDM2 Degrader-1 uses PROTAC tech to break down MDM2 with an inhibitor, linker, and E3 ligase ligand.