Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Se han encontrado 79382 productos de "Sales y derivados de API"
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3-Hydroxy-1-methylpyridinium Iodide
CAS:Producto controladoFórmula:C6H8NO·IForma y color:NeatPeso molecular:237.04Didecyl Dimethyl Ammonium Chloride
CAS:<p>Applications Didecyl Dimethyl Ammonium Chloride is a compound that exhibits some fungacidal and antimirobial functions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kanazawa, A. et al.: Antimicrob. Agents Chemother., 38, 945 (1994)l; Schultz, T.P. et al.: Phytochem., 54, 47 (2000);<br></p>Fórmula:C22H48N·ClForma y color:Light Beige To BrownPeso molecular:362.082-(2-Aminoethylamino)ethanol
CAS:Producto controlado<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>Fórmula:C4H12N2OForma y color:NeatPeso molecular:104.1509Methyl Acetoacetate
CAS:Producto controlado<p>Applications 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Ranu, B. et al.: J. Org. Chem. 65, 6270 (2000); Lu, J. et al.: Tetrahedron Lett., 41, 9075 (2000); Lu, J. et al.: Synlett., 1, 63 (2000);<br></p>Fórmula:C5H8O3Forma y color:NeatPeso molecular:116.12Ticagrelor Sulfoxide (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications Ticagrelor Sulfoxide is an impurity of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Fórmula:C23H28F2N6O5SForma y color:NeatPeso molecular:538.572-Oxo Clopidogrel Hydrochloride(Mixture of Diastereomers)
CAS:Producto controlado<p>Applications The essential intermediate metabolite from which the active metabolite of Clopidogel is formed.<br>References Feliste, R., et al.: Thromb. Res., 48, 403 (1987), Savi, P., et al.: Biochem. Pharmacol., 44, 527 (1992), Herbert, J., et al.: Cardiovasc Drug. Rev., 11, 180 (1993), Sugidachi, A., et al.: B. J. Pharmacol., 132, 47 (2001)<br></p>Fórmula:C16H17Cl2NO3SForma y color:NeatPeso molecular:374.28Ramipril
CAS:Producto controlado<p>Applications An antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite. Neuroprotective & Neuroresearch Product.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Fórmula:C23H32N2O5Forma y color:WhitePeso molecular:416.51Trandolaprilat Monohydrate
CAS:<p>Applications A metabolite of Trandolapril, an antihypertensive.<br>References Blankley, C.J., et al.: J. Med. Chem., 30, 992 (1987)<br></p>Fórmula:C22H30N2O5·H2OForma y color:Off White PowderPeso molecular:420.50FK-506-13C,D2 (Major) (Tacrolimus) (>85%)
CAS:Producto controladoFórmula:CC43D2H67NO12Pureza:>85%Forma y color:NeatPeso molecular:807.02N1-Acetyl Triethylenetetramine Trihydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications N1-Acetyl Triethylenetetramine is a monoacetylated metabolite of the selective CuII-chelator Triethylenetetramine (T776630).<br>References Murata, Y. et al.: Biomed. Res. Trace Elem., 4, 185 (1993): Lu, J. et al.: J. Clin. Pharmacol., 50, 647 (2010); Lu, J. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 859, 62 (2007);<br></p>Fórmula:C8H23Cl3N4OForma y color:NeatPeso molecular:297.651-(3-Hydroxypropyl)theobromine
CAS:Producto controladoFórmula:C10H14N4O3Forma y color:White To Off-WhitePeso molecular:238.243trans-Nerolidol
CAS:Producto controlado<p>Applications Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.<br></p>Fórmula:C15H26OForma y color:NeatPeso molecular:222.37Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C31H38ClN7O7S2•xH2OForma y color:White To Off-WhitePeso molecular:720.26A77 1726 (E/Z) Mixture
CAS:Producto controlado<p>Impurity Leflunomide USP Related Compound B<br>Applications rac A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective than injectable interferon beta 1a (Rebif®). Leflunomide USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Fórmula:C12H9F3N2O2Forma y color:NeatPeso molecular:270.21Leflunomide
CAS:Producto controlado<p>Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),<br></p>Fórmula:C12H9F3N2O2Forma y color:NeatPeso molecular:270.211,1'-[(5E)-5-Methyl-7-oxo-5-undecene-1,11-diyl] Bis[Theobromine]
CAS:Fórmula:C26H34N8O5Forma y color:NeatPeso molecular:538.60Rivaroxaban
CAS:<p>Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C19H18ClN3O5SForma y color:White To BeigePeso molecular:435.88Tacrolimus Hydrate
CAS:<p>Applications Tacrolimus Hydrate is a disease-modifying antirheumatic drugs (DMARDs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ogasawara, M., et al.: Mod. Rheumatol., 22, 831-836 (2012)<br></p>Fórmula:C44H69NO12·H2OForma y color:NeatPeso molecular:822.03N-Demethylivabradine
CAS:Producto controladoFórmula:C26H34N2O5Forma y color:Light Brown To BrownPeso molecular:454.56Riociguat-13C-d3
CAS:Producto controlado<p>Applications Riociguat-13C-d3 is the labelled analogue of Riociguat (R520000), which is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C1913CH16D3FN8O2Forma y color:NeatPeso molecular:426.43Leflunomide-d4
CAS:Producto controlado<p>Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases.This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),<br></p>Fórmula:C12D4H5F3N2O2Forma y color:NeatPeso molecular:274.23Edoxaban-d6
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C24H24D6ClN7O4SForma y color:Light Beige To Light BrownPeso molecular:554.09Treprostinil Ethyl Ester
CAS:Producto controladoFórmula:C25H38O5Forma y color:NeatPeso molecular:418.566Riociguat
CAS:Producto controlado<p>Applications Riociguat is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C20H19FN8O2Forma y color:NeatPeso molecular:422.41575-Chloro-2-thiophenecarboxylic Acid
CAS:Producto controlado<p>Applications 5-Chloro-2-thiophenecarboxylic Acid is a metabolite of Rivaroxaban (R538000).<br>References Brickner, S., et al.: J. Med. Chem., 39, 673 (1996), Sato, K., et al.: Eur. J. Pharmacol., 347, 231 (1998), Chang, P., et al.: IDrugs, 7, 50 (2004), Weinz, C., et al.: Drug Metab. Dispos., 37, 1056 (2009)<br></p>Fórmula:C5H3ClO2SForma y color:NeatPeso molecular:162.59Hexadecyltrimethylammonium Bromide
CAS:<p>Applications Hexadecyltrimethylammonium Bromide (CTAB) is a cationic surfactant used as a template in the synthesis of Mesoporous γ-Fe2O3.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yu, H.-h., et al.: Gongneng Cailiao, 42, 2005 (2011),<br></p>Fórmula:C19H42N·BrForma y color:NeatPeso molecular:364.45Ivermectin B1a-D2
CAS:Producto controlado<p>Applications Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.<br>References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178<br></p>Fórmula:C48H72D2O14Forma y color:NeatPeso molecular:877.115-Methylisoxazole-4-carboxylic Acid
CAS:Producto controladoFórmula:C5H5NO3Forma y color:NeatPeso molecular:127.10Apixaban PG Ester-I
CAS:Producto controlado<p>Applications Apixaban PG Ester-I is one of the multiple constituents extracted from Biebersteinia multifida, that exhibits inhibitory activity on acetylcholinesterase.<br>References Xiang, F., et al.: Faming Zhuanli Shenqing (2019), CN 109432093 A 20190308.<br></p>Fórmula:C28H30N4O6Forma y color:NeatPeso molecular:518.56Diclofenac Levomenthol Ester
CAS:Producto controladoFórmula:C24H29Cl2NO2Forma y color:NeatPeso molecular:434.399Iopromide-d3
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Labelled Iopromide. Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Muetzel, W., et al.: Am.J. Neuroradiol., 4, 350 (1983), Dawson, P., et al.: Acta Radiol. Diagn., 25, 253 (1984),<br></p>Fórmula:C18H21D3I3N3O8Forma y color:White To Light YellowPeso molecular:794.13Tolvaptan
CAS:Producto controlado<p>Applications Tolvaptan is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006);<br></p>Fórmula:C26H25ClN2O3Forma y color:White To Off-WhitePeso molecular:448.94Riluzole-13C,15N2
CAS:Producto controladoFórmula:C713CH5F315N2OSForma y color:Light Beige To Light YellowPeso molecular:237.18Macitentan-d4
CAS:Producto controlado<p>Applications Macitentan-d4 is an isotopic form of Macitentan (M105005). Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Emoto, N. Ensho to Men'eki, 20, 487 (2012);<br></p>Fórmula:C19H16D4Br2N6O4SForma y color:NeatPeso molecular:592.3Riluzole
CAS:<p>Applications A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Fórmula:C8H5F3N2OSForma y color:NeatPeso molecular:234.201,2,3,4-Tetradehydro Argatroban
CAS:Producto controlado<p>Applications 1,2,3,4-Tetrahydro Argatroban is a metabolite of Argatroban (A769000); a synthetic thrombin inhibitor and antithrombotic.<br>References Abiko, Y., et al.: Thromb. Res., 24, 285 (1981); Kikumoto, R., et al.: Biochemistry, 23, 85 (1984)<br></p>Fórmula:C23H32N6O5SForma y color:NeatPeso molecular:504.604-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone
CAS:Producto controlado<p>Impurity Rivaroxaban Impurity E<br>Applications 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone (Rivaroxaban Impurity E) is an impurity of Rivaroxaban (R538000), which is a antithrombotic agent and a FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C13H17ClN2O3Forma y color:NeatPeso molecular:284.74Dofetilide
CAS:Producto controlado<p>Applications Dofetilide is a potassium channel blocker. Antidysrhythmic drug.<br>References Carmeliet, D., et al.: J. Pharmacol. Exp. Ther., 262, 809 (1992); Norgaard, B.L., et al.: Am. Heart J., 137, 1062 (1999); Torp-Pedersen, C., et al.: N. Engl. J. Med. 341, 857 (1999);<br></p>Fórmula:C19H27N3O5S2Forma y color:White Or BeigePeso molecular:441.56Geranylgeraniol (Natural)
CAS:Producto controlado<p>Stability Light Sensistive, Temperature Sensitive<br>Applications Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteoclast formation, and kinase activation in vitro.<br>References Aiuchi, T., et al.: J. Biochem., 124, 300 (1998), Fisher, J.E., et al.: Proc. Natl. Acad. Sci. U.S.A. 96, 133 (1999), Montero, M.T., et al.: J. Immunol., 173, 4936 (2004), Campia, I., et al.: Br. J. Pharmacol., 158, 1777 (2009),<br></p>Fórmula:C20H34OForma y color:NeatPeso molecular:290.48Zephirol-d7
CAS:Producto controlado<p>Applications Labelled Zephirol. Quaternary ammonium composition to treat herpes, pseudomonas, staph, hepatitis and other infectious diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Berr, S., et al.: J. Phys. Chem., 91, 4760 (1987), Jones, M., et al.: Eur. J. Pharm. Biopharm., 48, 101 (1999), Okano, L., et al.: Langmuir, 16, 3119 (2000),<br></p>Fórmula:C21H31D7ClNForma y color:NeatPeso molecular:347.03Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
CAS:Fórmula:C14H13NO4SForma y color:NeatPeso molecular:291.32Bosentan-d4
CAS:Producto controlado<p>Applications Labelled Bosentan (B675900). A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive.<br>References Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)<br></p>Fórmula:C27H25D4N5O6SForma y color:NeatPeso molecular:555.64Bimatoprost-d5
CAS:Producto controlado<p>Applications Labelled Bimatoprost (B386800). Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α.<br>References Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001), Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003), Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),<br></p>Fórmula:C25H32D5NO4Forma y color:NeatPeso molecular:420.6Probenecid Acyl β-D-Glucuronide >90%
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications The major metabolite of Probenecid (P755000).<br>References Blanckaert, N., et al.: Biochem. J., 171, 203 (1978), Worrall, S., et al.: Life Sci., 56, 1921 (1995), Presle, N., et al.: Drug Metab. Disos., 24, 1050 (1996), Akira, K., et al.: J. Pharmacol. Toxicol. Methods, 37, 237 (1997), Terrier, N., et al.: Mol. Pharmacol., 56, 226 (1999),<br></p>Fórmula:C19H27NO10SPureza:>90%Forma y color:NeatPeso molecular:461.481-(4-(Trifluoromethoxy)phenyl)-2-thiourea
CAS:Producto controladoFórmula:C8H7F3N2OSForma y color:NeatPeso molecular:236.21Brinzolamide Hydrochloride
CAS:Producto controlado<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Fórmula:C12H21N3O5S3·ClHForma y color:NeatPeso molecular:419.974-Demethoxy-4-hydroxy Apixaban
CAS:Producto controlado<p>Applications 4-Demethoxy-4-hydroxy Apixaban is a metabolite of Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C24H23N5O4Forma y color:NeatPeso molecular:445.47Dihydro FK-506
CAS:Producto controlado<p>Impurity Tacrolimus 8-Propyl Analog (USP)<br>Applications A novel analog of FK-506 (F370000) macrocycle.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kino, T., et al.: J. Antibiot., 40, 1249 (1987), Motamedi, H., et al.: J. Bacteriol., 178, 5243 (1996), Dai, Y., et al.: Drug Metab. Dispos., 34, 836 (2006),<br></p>Fórmula:C44H71NO12Forma y color:NeatPeso molecular:806.03N-(R)-Glycidyl Phthalimide
CAS:Producto controlado<p>Applications Reagent used for the simultaneous preparation of amino alcohol solvating agents as well as preparation of orally available anticoagulants.<br>References Roehrig, S. et al: J. Med. Chem., 48, 5900 (2005); Bozkurt, S. et al: Tetra: Asymm., 22, 541 (2011);<br></p>Fórmula:C11H9NO3Forma y color:NeatPeso molecular:203.19R-(+)-Warfarin
CAS:Producto controlado<p>Applications The R-(+)-form of Warfarin (W498500). Coumarin anticoagulant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hagan, E.C., et al.: J. Am. Pharm. Assoc. Sci. Ed., 42, 379 (1953), Bell, R.G., et al.: Biochemistry, 11, 1959 (1972), Valente, J.E., et al.: J. Med. Chem., 20, 1489 (1977), Back, N., et al.: Pharmacol. Res. Commun., 10, 445, (1978), Babhair, S.A., et al.: Anal. Profiles Drug Subs., 14, 423 (1985), Takahashi, H., et al.: Echizen, Clin. Pharmacokinet., 40, 587 (2001),<br></p>Fórmula:C19H16O4Forma y color:NeatPeso molecular:308.33Methylamine (40% w/w in H2O)
CAS:Producto controladoFórmula:CH5NForma y color:Colourless LiquidPeso molecular:31.06Lesinurad
CAS:Producto controlado<p>Applications Lesinurad is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.<br>References Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WO 2011159732 A1 20111222 (2011); Crittenden, D. B. et al.: Clinical Investigation 1, 1563-1575 (2011)<br></p>Fórmula:C17H14BrN3O2SForma y color:NeatPeso molecular:404.283’-Hydroxy Warfarin
CAS:Producto controlado<p>Applications A new metabolite of Warfarin using Cunninghamella elegans.<br>References Wong, Y. W., et al.: J. Pharma. Sci., 80, 305 (1991)<br></p>Fórmula:C19H16O5Forma y color:NeatPeso molecular:324.33Dofetilide-d4
CAS:Producto controlado<p>Applications Potassium channel blocker.<br>References Carmeliet, D., et al.: J. Pharmacol. Exp. Ther., 262, 809 (1992), Norgaard, B.L., et al.: Am. Heart J., 137, 1062 (1999), Torp-Pedersen, C., et al.: N. Engl. J. Med. 341, 857 (1999)<br></p>Fórmula:C19H23D4N3O5S2Forma y color:NeatPeso molecular:445.5924,32-Bis-O-(tert-butyldimethylsilyl)-FK-506-13C, D2 (Major)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications An intermediate in the preparation of labelled FK-506 (Tacrolimus)<br>References Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., et al.: Brit. Med. J., 318, 1104 (1999),<br></p>Fórmula:C5513CH95D2NO12Si2Forma y color:NeatPeso molecular:1035.541-(3-Carboxypropyl)-3,7-dimethylxanthine
CAS:Producto controlado<p>Applications A metabolite of Pentoxifylline (P276500).<br>References Yamaoka, K., et al.: J. Pharmacokin. Biopharm., 6, 165 (1978), Cottam, H.B., et al.: J. Med. Chem., 39, 2 (1996), Janvilisri, T., et al.: J. Biol. Chem., 278, 20645 (2003),<br></p>Fórmula:C11H14N4O4Forma y color:NeatPeso molecular:266.25Diethyl Phthalate
CAS:<p>Applications A phthalate metabolite with genotoxic effect. This compound is a contaminant of emerging concern (CECs).<br>References Reyes, F., et al.: J. Clin. Endocrinol. Metab., 37, 74 (1973), Engel, S., et al.: Neurotoxicology, 30, 522 (2009),<br></p>Fórmula:C12H14O4Forma y color:ColourlessPeso molecular:222.24
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