Monosacáridos

<p>6-O-Malonylglycitin is a glycosylated flavonoid that belongs to the group of isoflavones. It is found in a variety of plants, including soybeans and fava beans. 6-O-Malonylglycitin has been shown to be an effective inhibitor of β-glucosidase activity at temperatures below 37°C, which overlaps with the range of temperatures where it inhibits glycitein production. This inhibition may be due to its pleiotropic effects on various treatments, such as its ability to inhibit cancer cell growth by inhibiting protein synthesis and inducing apoptosis. 6-O-Malonylglycitin also has synergistic effects when used concomitantly with chromatographic markers, such as high performance liquid chromatography (HPLC), which can be used to analyze the levels of endogenous compounds in human blood samples.</p>

<p>Resource for the synthesis of 2-azido- and 2-deoxy-L-glucoses and 1,2-epoxides</p>

<p>Losartan N2-glucuronide is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide modification. It is synthesized with click chemistry to create an oligosaccharide. This product is synthesized from saccharides (carbohydrates) and polysaccharides. Losartan glucuronide is a complex carbohydrate that has been glycosylated and sugar modified for high purity.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-b-D-galactopyranose (TAZ) is an aromatic heterocyclic sugar compound that is used in pharmaceutical formulations. It has low toxicity and can be synthesized using a number of methods. TAZ has been shown to have antifungal effects against Candida albicans and antitumor effects against cancer cells. TAZ also inhibits the activity of teniposide, which is a drug used for the treatment of leukemia. TAZ may be effective against cancer cells by acting as an amido donor and changing the conformation of the cyclic peptide.</p>

<p>Methyl β-D-ribopyranoside is a sugar alcohol that belongs to the group of pentoses. It is a potential precursor for the synthesis of phosphite, which is a reactive anion used in organic chemistry. Methyl β-D-ribopyranoside has been shown to regulate the growth of bacteria and fungi by altering their metabolic pathways. This compound also has shown to be programmed death in certain bacterial strains, although it is not clear how it induces this programmed death. Methyl β-D-ribopyranoside can also affect the rhizosphere and can be used as a substrate for anions and sugar alcohols.</p>

<p>(-)-D-Noviose is a naturally occurring sulfoxide that was first isolated from the tubercles of tuberculosis patients. It is a biosynthetic precursor to tiacumicin, an antibacterial agent. In addition, (-)-D-Noviose has been shown to act as a chaperone and inhibit cancer cells in vitro. (-)-D-Noviose binds to the cysteine residues of proteins, preventing their oxidation and subsequent aggregation. This prevents the cross-linking of proteins that leads to cellular damage and death.</p>

<p>Promotes hyaluronic acid production; synthetic building block</p>

<p>D-Glucosamine-6-phosphate sodium salt is a custom synthesis of an oligosaccharide, polysaccharide, and carbohydrate. The chemical modification of this compound includes methylation, glycosylation, and carbamylation. This product has high purity with a fluorination level of 98%.</p>

<p>Kifunensine is a potent and specific inhibitor of plant and animal α-mannosidase I with IC50 in nanomolar range. It inhibits the enzyme isoforms in Golgi apparatus (GMI) and endoplasmatic reticulum (ERMI). The compound prevents mannose trimming on glycoproteins and shifts the glycoform content from complex to oligomannose type. It's used for the production of recombinant therapeutic glycoproteins with mannose rich N-linked glycans.</p>

<p>Intermediate in the synthesis of dapagliflozin</p>

<p>Methyl 2,3,4,6-tetra-O-benzyl-D-galactopyranoside is a trisaccharide that binds to the fluorescent chromophore. It has been shown to have strong binding activity and can be used for the labeling of carbohydrates. Methyl 2,3,4,6-tetra-O-benzyl-D-galactopyranoside is also used in assays to detect toxins or as a fluorescent label for polymers. This compound can be synthesized by reacting methyl 4,6-dibenzyloxybenzoate with glucose in methanol.</p>

<p>1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-toluoyl-D-ribofuranose is a synthetic sugar that can be modified to produce oligosaccharides or polysaccharides. It has a CAS number of 120143-22-8 and is composed of a sugar molecule with an acetyl group on the 2' position and toluene sulfonyl group on the 3' position. This modification can be used for glycosylation or methylation reactions. 1,2-Di-O-acetyl -3,4,6,-triaminopyrimidine is also known as fluorinated ribofuranose.</p>

<p>N-Ethyldeoxynojirimycin hydrochloride is a mutant of the natural compound, deoxynojirimycin. The chemical structure of this compound is similar to that of the natural product and its molecular weight is 547.7 g/mol. N-Ethyldeoxynojirimycin hydrochloride has been shown to interact with the bacterial chaperone GroEL and enhance the activity of this protein. Further study has shown that this agent binds to GroEL in a manner that allows it to bind directly to ATPase domains I and II, leading to an increase in ATPase activity.</p>

<p>1,6-Anhydro-3,4-O-isopropylidene-b-D-galactopyranose is a custom synthesis of a complex carbohydrate that has been modified with methylation and glycosylation. It is a saccharide with the CAS number 52579-97-2. This product is highly pure and can be fluorinated for synthesizing other sugars or carbohydrates. The purity of this product is greater than 98%.</p>

<p>1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronide methyl ester is a protected D-glucoronic acid with an alpha bromide at the anomeric position ready to undergo glycosylation reactions with suitable glycoside acceptors. Pharmaceutically active compounds have been used as acceptors to form β-linked D-glucuronide prodrugs which can be used to modify pharmacokinetics, improve solubility and lower the toxicity of the drug.</p>

<p>Methyl 2,3,5-tri-O-benzoyl-b-D-arabinofuranoside is a custom synthesis of an Oligosaccharide with a molecular formula of C12H22O11. It has CAS No. 1093344-99-0 and Methylation, Glycosylation, Carbohydrate, Click modification, saccharide, sugar. This product is a high purity product that is Fluorination and Synthetic.</p>

<p>3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-1-O-methanesulfonyl-aDribofuranoside is a glycosylation agent that reacts with the reducing end of glycogen to form a glycosidic linkage. The compound is used in the synthesis of complex carbohydrates and saccharides. 3,5-Di-O-benzoyl-2,2,-difluoro 1,1'-O-(methanesulfonyl) aDribofuranoside is often methylated at the 3' position to obtain 3,5diOBenzoyl 2,2'-difluoro 1,1'-O-(methylsulfonyl)-aDribofuranoside. This compound can be used for click chemistry reactions and modification of polysaccharides. It has been shown to have antiinflammatory effects on</p>

<p>Specific and potent inhibitor of lysosomal α-galactosidase with IC50 in nanomolar range. It acts as pharmacological chaperone and assists folding of the wild type and mutant versions of the enzyme. It places itself in the instable active site and prevents the damage to the enzyme during the passage through Golgi apparatus, endoplasmatic reticulum and lysosome axis. The exposure to this compound leads to increased levels of functional α-galactosidase in models for lysosomal storage disorders and brings therapeutic benefits to patients with Fabry disease.</p>

<p>N-Acetyl-a-D-glucosamine-1-phosphate disodium salt (NACP) is a complex carbohydrate that is used as a synthetic sugar. It can be used to modify saccharide, glycosylations, or methylations. NACP has been shown to be stable at high temperatures and pressures. The compound has been fluorinated and click modified for the synthesis of other sugars. NACP has CAS No. 31281-59-1, which is the molecular formula of C8H14FO6Na2O11P2.</p>

<p>Please enquire for more information about 6-O-Desmethyl donepezil glucuronide sodium (Mixture of Diastereomers) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,5-Anhydro-2,3,4-tri-O-benzoyl-6-deoxy-D-arabino-hex-1-enitol is a high purity sugar with a click modification. It is a synthetic monosaccharide that is an important building block for complex carbohydrates. This compound can be modified through methylation, glycosylation, and custom synthesis to produce desired compounds. The 1,5 Anhydro 2,3,4 tri O benzoyl 6 deoxy D arabino hex 1 enitol has shown activity against the fluoroquinolone resistant bacteria Staphylococcus aureus and Mycobacterium tuberculosis. It has also been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>

<p>Canagliflozin is an oral diabetes drug that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking reabsorption of glucose in the kidney, thereby lowering blood sugar levels. Canagliflozin has been shown to be a potent inhibitor of insulin resistance and has been used clinically in combination with metformin hydrochloride. The chemical stability of canagliflozin is dependent on its particle size, which can range from 10 micrometres to 100 micrometres. A number of analytical methods have been developed for canagliflozin, including high performance liquid chromatography with ultraviolet detection, gas chromatography with mass spectrometry detection, and dihedral angle analysis. Canagliflozin is an example of a polymorphic compound: it exists as two enantiomers due to chiral symmetry.</p>

<p>L-[1-13C]Fucose is a custom synthesis. It is an oligosaccharide that consists of D-fucose, which is a sugar found in the cell wall of bacteria. L-[1-13C]Fucose has been used as a substrate for methylation reactions and click chemistry modifications to study the binding affinity of various proteins. This compound has also been used in saccharide modification studies and glycosylation reactions.</p>

<p>Intermediate in the synthesis of Decitabine</p>

<p>D-Talitol is a drug that is used to treat eye disorders and chronic pulmonary diseases. It belongs to the class of drugs called xylitol dehydrogenase inhibitors. D-Talitol inhibits the enzyme xylitol dehydrogenase, which converts xylitol into a different sugar called sorbitol. Sorbitol accumulates in certain parts of cells, such as the mitochondria, and can disrupt cellular processes by inhibiting oxidative phosphorylation and glycolysis. In addition, there are other effects of sorbitol accumulation that may lead to mitochondrial dysfunction, including inhibition of protein synthesis, induction of apoptosis (cell death), and inhibition of cell proliferation. D-Talitol has been shown to inhibit the growth of chronic kidney cells in culture by interfering with cellular metabolism in mitochondria.<br>A kinetic study has also shown that D-Talitol inhibits b-raf activity at concentrations that are not cytotoxic. This suggests that D-Talitol may be useful for</p>

<p>2-C-Methyl- D- xylonic acid g- lactone is a monosaccharide that can be used in the synthesis of oligosaccharides and complex carbohydrates. This compound is a fluorinated carbohydrate, which has been modified to include a methyl group at the C2 position. The chemical name for this compound is 2-C-Methyl-D-xylonic acid g-lactone and it has CAS No. 4983-92-1. This compound can be synthesized as a custom order and its purity exceeds 99%. Its synthesis can involve glycosylation or methylation, depending on the desired product.</p>

<p>UDP-2-amino-2-deoxy-D-glucose is a modification of glucose. It is an organic compound that can be used in the synthesis of oligosaccharides and polysaccharides. It can be methylated or glycosylated with other sugars, such as galactose, to form complex carbohydrates. UDP-2-amino-2-deoxyglucose also has a high purity and CAS number.</p>

<p>Trans-zeatin-7-glucoside is an abscisic acid (ABA) metabolite that can be found in plant tissue. It is used as a natural product to regulate growth and development. Trans-zeatin-7-glucoside has been shown to inhibit the biosynthesis of gibberellins, which are plant hormones that promote cell elongation. This compound is purified from plant tissues by chromatographic methods, such as reversed phase HPLC or ion exchange chromatography. The sample preparation involves extraction with a solvent such as methanol or chloroform followed by purification on an analytical column. Immunoaffinity chromatography is also used for sample preparation, which involves binding to antibody molecules on the surface of a solid support material. Trans-zeatin-7-glucoside can be detected using analytical methods such as gas chromatography or liquid chromatography coupled with mass spectrometry. Trans-zeatin-7-</p>

<p>O-(D-glucopyranosylidene)amino N-phenylcarbamate is a synthetic monosaccharide that is used in our laboratory as an intermediate for the synthesis of complex carbohydrates. It is also used in the modification of polysaccharides and glycosylations. This compound has been shown to be stable to hydrolysis, methylation, and oxidation. O-(D-glucopyranosylidene)amino N-phenylcarbamate has been shown to be a high purity product with a CAS number of 104012-84-2.</p>

<p>4-Methylphenyl β-D-thiogalactopyranoside is a custom synthesis. The chemical is an Oligosaccharide, Polysaccharide, Modification, saccharide, Methylation, Glycosylation, Carbohydrate that has been Fluorinated and Synthetically Modified. It is a High purity product with the CAS No. 28244-98-6.</p>

<p>2,3-O-Isopropylidene-D-lyxonic acid-1,4-lactone (2,3-OIPDL) is a fluorinated polysaccharide that is synthesized from glycosylation of 1,4-lactone with 2,3-O-isopropylidene D-lyxonic acid. This compound has been shown to have high purity and is used in the modification of carbohydrates.</p>

<p>Component of peptidoglycan in bacterial cell walls. Peptidoglycan is a mesh-like polymer, made of a glycan backbone containing alternating subunits of N‐acetylglucosamine (GlcNAc) and N‐acetylmuramic acid (MurNAc). An enzyme substrate that is used to characterize and differentiate MurNAc and GlcNAc kinases.</p>

<p>4,6-O-Benzylidene-D-glucose is a potent inhibitor of the enzyme dibutyltin oxide, which is involved in the synthesis of energy. It has been shown to have clinical activity in rat cardiomyocytes and has been tested in clinical studies. 4,6-O-Benzylidene-D-glucose inhibits enzymes by forming hydrogen bonds with their substrates. This compound also interacts with hydrochloric acid to form a stable complex that prevents it from interacting with other molecules. 4,6-O-Benzylidene-D-glucose is rapidly broken down into glucose and benzaldehyde when it reacts with carbonyl groups or amines. The asymmetric synthesis of this compound can be achieved using an intramolecular hydrogen transfer reaction. <br>4,6-O-Benzylidene glucose is derived from D-mannose derivatives and contains a hydroxyl group on the central carbon</p>

<p>1,2,3,4,6-Penta-O-pivaloyl-a-D-glucopyranoside is a synthetic carbohydrate that has been fluorinated and methylated. This product is a modification of the natural compound D-glucose. It is an oligosaccharide which contains six pivaloyl groups attached to the 1-, 2-, 3-, 4-, 6-, and 7-positions on the glucose molecule. This product can be used in the synthesis of polysaccharides and glycosylations.</p>

<p>Phenyl 3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxyformamido)-b-D-glucopyranoside is a glycosylation product of the naturally occurring phenyl 2,3,4,6-tetraacetate. It is a white to off white powder that is stable in air and water. Phenyl 3,4,6-triacetyl 1 -thio 2-(2,2,2 trichloroethoxyformamido) b D glucopyranoside is soluble in methanol and ethanol but insoluble in water. This compound has been used as a monosaccharide or polysaccharide modification for click chemistry and complex carbohydrate studies.</p>

<p>Arabinose is a pentose sugar that has been shown to have antimicrobial properties. It inhibits the growth of bacteria by binding to their ribosomes and interfering with protein synthesis. Arabinose has also been shown to inhibit the growth of bone cancer cells in mice, which may be due to its ability to stimulate the production of growth factor-β1. The biochemical properties of arabinose are similar to those of d-arabinose, an active analogue that is used as a water vapor pump inhibitor. X-ray crystal structures have been obtained for both compounds, and they show that they differ in the position of one hydrogen atom on the sugar ring.</p>

<p>3-Aminopropyl α-D-glucopyranoside is a monomer that can be used to produce polymers. It has been shown to be effective in methylation, saccharide and oligosaccharide modifications. 3-Aminopropyl α-D-glucopyranoside is an alpha glucosidase inhibitor. The compound also inhibits the action of other enzymes, such as glycosidases, which are responsible for breaking down glycogen and starch. 3-Aminopropyl α-D-glucopyranoside is a white powder with a melting point of about 150°C and boiling point of about 300°C.</p>

<p>Methyl 2-acetamido-2-deoxy-α-D-glucopyranoside is a fluorinated sugar that is used as a building block in the synthesis of complex carbohydrates. It can be custom synthesized to order with purity levels up to 99.8%. The modification process includes methylation, monosaccharide, and polysaccharide modifications. This product is not intended for use in humans or animals.</p>

<p>Superdisintegrant used in pharmaceutical formulations</p>

<p>2-O-Methyl-D-glucose is an aldohexose that is used in the synthesis of a number of biological compounds. It has been shown to inhibit the growth of cancer cells by interfering with the synthesis of fatty acids and proteins.</p>

<p>Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-fluoro-a-D-glucopyranoside is a sugar that is synthetically modified. This product has been fluorinated and glycosylated with a benzoyl group at C2 position. It contains methyl groups attached to the ring carbons at C1 and C6 positions. The product is also an oligosaccharide that contains two monosaccharides (sugar units) linked by an alpha (1→4) glycosidic bond. Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-fluoro-a-Dglucopyranoside can be used as a synthetic building block for the synthesis of complex carbohydrate structures.</p>

<p>Radiopaque contrast agent; diagnostic aid for myelography</p>

<p>D-Glucosamine-3-O-sulphate is a naturally occurring sugar found in the human body. It is a structural component of a number of important molecules, such as glycoproteins, heparin, and glycosaminoglycans. D-Glucosamine-3-O-sulphate has been shown to inhibit the growth of mouse tumor cells by activating effector proteins that induce apoptosis and inhibit axonal growth. It also promotes oligodendrocyte differentiation, which may be due to its ability to increase heparin levels and reduce hepcidin expression.</p>

<p>Sorbitol, also known as glucitol, occurs widely in plants, such as, the fruits of the Sorbus and Crataegus spp.  Commercially it is produced by the catalytic hydrogenation of glucose (Collins, 2006).  Sorbitol is approved as a sugar substitute with the E number 420 and has ‘generally recognized as safe’ status (GRAS) from the US Food and Drug Administration. It is about 60% as sweet as sucrose and is a mild laxative.  Sorbitol has a wide range of other functional properties, including: humectancy, plasticizing ability, non-cariogenicity, and good chemical stability in harsh conditions, such as, alkaline pH and heat. Toothpaste production is the second largest application of sorbitol, accounting for 50,000 tons a year in Western Europe alone.  Other important uses of sorbitol as a humectant, include: formulation of cough syrups, multivitamin preparations, emulsions, and suspensions (O’Neil, 2013).</p>

<p>1,2,3,5-Tetra-O-acetyl-b-L-ribofuranose is a synthetic carbohydrate that can be modified with fluorination, methylation, or monosaccharide. It is a monomeric sugar that is used in the synthesis of oligosaccharides and polysaccharides. The compound has been shown to have antiviral properties against human immunodeficiency virus type 1 (HIV-1).</p>

<p>3-O-benzyl-diacetonide-d-glucose is a synthetic monosaccharide that can be used as a building block for oligosaccharides and polysaccharides. It is custom synthesized to meet your specific needs and can be modified with fluorination, methylation, or glycosylation. 3-O-benzyl-diacetonide-d-glucose has been shown to have high purity and is available in small quantities for custom synthesis.</p>

<p>Phenyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido b-D-selenoglucopyranoside is a chemical compound that is used in the synthesis of saccharides and oligosaccharides. It has been modified with the Click reaction to give it a reactive group. This modification can be used for glycosylation or for incorporation into polysaccharides such as starch. Phenyl 3,4,6-tri-O-acetyl-2-deoxy b -D selenoglucopyranoside is a high purity synthetic compound that is available in custom synthesis quantities.</p>

<p>Tetra-O-acetyl-6-azido-6-deoxy-a-D-glucopyranose is a carbohydrate that has been modified to include a fluorine atom. This modification can be carried out using a variety of methods, including chlorination or bromination with elemental fluorine or chlorine gas, or by direct replacement of the hydroxyl group with a fluorine atom. Tetra-O-acetyl-6-azido-6-deoxy-aDglucopyranose is used in the synthesis of complex carbohydrates and glycosides. It can also be methylated, glycosylated, and click modified.</p>

<p>Potent and specific inhibitor of α-mannosidase I. It is active against the Golgi isoform (GMI) of the enzyme and blocks carbohydrate branch elongation from immature to complex and hybrid N-glycans. Its anti-viral activity against HIV-1 is characterized by the alteration of N-glycan pattern and shift to high-mannose glycans on viral glycoprotein gp120, resulting in decreased infectivity of newly synthesized virions.</p>

<p>1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose is a high purity product custom synthesized for research purposes. It is a sugar that has been modified by the Click modification and fluorination. 1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose is an oligosaccharide with a complex carbohydrate structure that can be used in glycosylation reactions. This product is a saccharide with a CAS number of 19126-99-9.</p>