APIs para investigación e impurezas

Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.

o-Desmethyl venlafaxine N-dimer is a metabolite of venlafaxine that has been identified in human plasma. It is a white to off-white crystalline powder with a melting point of about 175°C. The purity of the product is more than 98%. It is soluble in methanol and ethanol, but insoluble in water. The o-desmethyl venlafaxine N-dimer was developed as an analytical reference standard for use in HPLC analysis of venlafaxine and its metabolites and impurities.

Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.

(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt is a synthetic drug product. It is an impurity standard in the synthesis of Metabolism studies. The CAS number is 1714147-50-8 and the chemical name is (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2 methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5dihydroxyheptenoic acid sodium salt. The molecular weight is 781

Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.

Pantoprazole sulfone N-oxide is a prodrug that is converted to the active form pantoprazole in the stomach where it inhibits gastric acid secretion. Pantoprazole sulfone N-oxide has been shown to be genotoxic, and can cause polyvinyl chloride to degrade when stored together. Reconstituted solution of this drug should be used within 24 hours after reconstitution, as the chemical stability of this drug decreases rapidly. Validation studies have been conducted on different analytical methods for determining pantoprazole concentrations in reconstituted solutions, and these methods have been harmonized with those published by the United States Pharmacopeia (USP). The pump inhibitor activity of pantoprazole sulfone N-oxide has been demonstrated in dogs, and it is also useful for treating acid reflux disease in humans. Pantoprazole sulfone N-oxide is unstable at high temperatures (>25°C), so should not be refrigerated or

2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.
2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antif

2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].

(S)-3-((R)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a drug product of the drug development industry. It is a metabolite of 3-(1,2,4-triazol-1-ylmethyl)thiazolidine-4-carboxylic acid and has been used as an analytical standard for HPLC methods. The compound has been shown to be naturally occurring in humans. (S)-3-(1,2,4-Triazol-1ylmethyl)thiazolidine 4 carboxylic acid is also used as the impurity standard for the API 3-(1,2,4 triazol 1ylmethyl)thiazolidine 4 carboxylic acid.

(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.

CPI 0610 is a medicinal compound that acts as a potent inhibitor of protein phosphorylation. It has been shown to inhibit the cell cycle and promote apoptosis in Chinese hamster ovary cells. CPI 0610 is an effective inhibitor of kinase activity in cancer cells, leading to decreased tumor growth and increased survival rates. In preclinical studies, CPI 0610 has demonstrated efficacy against a wide range of cancers, including breast, prostate, and lung cancer. This inhibitor has also been shown to be effective in human cancer cell lines, making it a promising candidate for future cancer therapies.

N-Desbispropyl-N-pentyl-2-methyl ropinirole is an analytical reference standard. This product is a high purity, drug development, and API impurity. It is a CAS No. 249622-60-4 and has a niche, drug product, and impurity standard. This item is for Research and Development, High purity, Drug development, API impurity, HPLC standard, CAS No. 249622-60-4, niche, drug product, Impurity standard, Metabolite, pharmacopoeia Custom synthesis of natural or synthetic origin.

Lysolecithin is an analog of the phospholipid lecithin that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cell signaling and regulation. Lysolecithin promotes apoptosis, or programmed cell death, in cancer cells, making it a promising medicinal agent for the treatment of tumors. Studies have also shown that lysolecithin can inhibit protein kinase activity in human urine and inhibit the growth of cancer cells in Chinese hamsters. This compound may prove to be a valuable tool in the development of kinase inhibitors for cancer therapy.

(R)-(+)-1,1,2-Triphenyl-1,2-ethanediol is a heterocyclic compound with a five-membered ring. It is chiral and has two stereogenic centers in its structure. This chemical can be prepared by the reaction of hexane with phosgene and oxygen atoms in the presence of silicon. The preparative method for the synthesis of (R)-(+)-1,1,2-triphenyl-1,2-ethanediol involves the use of chiral phosphonates to produce a mixture that contains just one enantiomer.

o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.