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APIs para investigación e impurezas

APIs para investigación e impurezas

Los ingredientes farmacéuticos activos (API) son las sustancias en los medicamentos responsables de sus efectos terapéuticos. En esta sección, encontrarás una amplia variedad de API destinados a uso en investigación. Estos compuestos son esenciales para el desarrollo, prueba y validación de nuevas formulaciones farmacéuticas. En CymitQuimica, ofrecemos API de alta calidad para apoyar la investigación en el descubrimiento y desarrollo de fármacos.

Subcategorías de "APIs para investigación e impurezas"

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  • Desisobutyl-N-butyl bortezomib

    CAS:

    Desisobutyl-N-butyl bortezomib is a drug product that has been custom synthesized for the purpose of research and development. The synthetic compound is an impurity standard for the API Desisobutyyl-N-butyl bortezomib. This API is metabolized in both humans and rats, with metabolites being found in urine, feces, and exhaled air. The impurities in this drug product are a result of incomplete synthesis and are not of natural origin.

    Fórmula:C19H25BN4O4
    Pureza:Min. 95%
    Peso molecular:384.2 g/mol

    Ref: 3D-EUB01135

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  • Hydrocotarnine hydrochloride

    CAS:

    Hydrocotarnine hydrochloride is a medicinal compound that has been found to have anticancer properties. It is an inhibitor of protein kinases, which are enzymes that play a key role in regulating cell cycle progression and apoptosis. Hydrocotarnine hydrochloride has been shown to induce apoptosis in cancer cells, making it a promising candidate for the development of novel cancer therapies. This compound has also been identified as a potential inhibitor of tumor growth in Chinese medicine. In vitro studies have demonstrated that hydrocotarnine hydrochloride inhibits the proliferation of various cancer cell lines, suggesting its potential as a therapeutic agent for the treatment of cancer.

    Fórmula:C12H16ClNO3
    Pureza:Min. 95%
    Peso molecular:257.71 g/mol

    Ref: 3D-FAA98555

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  • Deschloro amlodipine

    CAS:

    Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br> br> Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4

    Fórmula:C20H26N2O5
    Pureza:Min. 95%
    Peso molecular:374.43 g/mol

    Ref: 3D-NDA15052

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  • Linagliptin impurity E

    Producto controlado
    CAS:

    Linagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.

    Fórmula:C25H28N8O2
    Pureza:Min. 95%
    Peso molecular:472.54 g/mol

    Ref: 3D-IB106310

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  • Tenofovir disoproxil

    CAS:

    Tenofovir disoproxil is the disoproxil fumarate salt of tenofovir. It is a nucleoside reverse transcriptase inhibitor that has been shown to be effective in the treatment of chronic hepatitis B virus (HBV) in combination with emtricitabine and as a single agent in the treatment of HIV-1 infection. Tenofovir disoproxil is available as tablets, capsules, or oral solution. The drug has been shown to cause an increase in serum creatinine levels, which may be due to inhibition of renal tubular secretion of creatinine by tenofovir. This drug should not be used with alafenamide and tenofovir because it can lead to kidney failure and death.

    Fórmula:C17H28N5O7P·(C4H4O4)
    Pureza:Min. 95%
    Peso molecular:445.41 g/mol

    Ref: 3D-XGC28415

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  • (S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid

    CAS:

    (S)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a synthetic compound that is used as an impurity standard for HPLC. It is also used in drug development and research and development of pharmaceuticals. This product was made through custom synthesis and is not natural.

    Fórmula:C9H12N2O4S
    Pureza:Min. 95%
    Peso molecular:244.27 g/mol

    Ref: 3D-IO145580

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  • (2S,4R)-Fosinopril sodium salt

    CAS:

    (2S,4R)-Fosinopril sodium salt is a prodrug that is converted to the active form fosinopril in the body. It is used to treat high blood pressure and heart failure. Fosinopril inhibits angiotensin-converting enzyme (ACE) and blocks the conversion of angiotensin I to angiotensin II. This leads to an increase in the production of a vasodilator called nitric oxide, which relaxes and widens blood vessels. Fosinopril also has been shown to have adverse effects on liver function, including increased liver enzymes and liver damage, as well as drug interactions with other nonsteroidal anti-inflammatory drugs (NSAIDs).

    Fórmula:C30H45NNaO7P
    Pureza:Min. 95%
    Peso molecular:585.64 g/mol

    Ref: 3D-GEC35341

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  • (4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone

    CAS:
    (4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone is a drug product that is Custom synthesized to meet the requirements of pharmacopoeia, analytical, and drug development. It has been studied for its metabolism and toxicity profile in animals. This compound is a metabolite of chlorpheniramine, which is used as an antihistamine. Metabolites of this compound have also been identified in humans. The CAS Registry Number for this compound is 154356-96-4.
    Fórmula:C16H15ClO2
    Pureza:Min. 95%
    Peso molecular:274.74 g/mol

    Ref: 3D-IC20310

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  • (+)-Cis-phenothrin

    CAS:

    Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.

    Fórmula:C23H26O3
    Pureza:Min. 95%
    Peso molecular:350.4 g/mol

    Ref: 3D-BCA18688

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  • Vandetanib N-oxide

    CAS:

    Vandetanib N-oxide is a drug product that is custom synthesized for research and development purposes. It has been shown to have high purity, analytical, and natural properties. Vandetanib N-oxide can be used as a metabolite or impurity standard in pharmacopoeias, such as the USP. The compound also has niche use in drug development and metabolism studies.

    Fórmula:C22H24BrFN4O3
    Pureza:Min. 95%
    Peso molecular:491.40 g/mol

    Ref: 3D-XWC03022

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  • Remdesivir impurity 3 HCl

    CAS:

    Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0

    Fórmula:C9H19NO2·HCl
    Pureza:Min. 95%
    Peso molecular:209.71 g/mol

    Ref: 3D-IR177100

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  • N-Formyl Saxagliptin


    N-Formyl Saxagliptin is an analytical standard for HPLC. It is used as a drug development and API impurity in the pharmaceutical industry. It was synthesized by reacting formaldehyde with the amino acid L-glutamic acid, followed by purification to remove any other contaminants. The CAS number for this chemical is 57847-82-0.

    Pureza:Min. 95%

    Ref: 3D-IF162360

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  • 2-(4-Formylphenyl)propionic acid - Racemic

    CAS:

    2-(4-Formylphenyl)propionic acid is a racemic mixture of 2-formylphenylacetic acid and 4-formylphenylacetic acid. This compound is used in the treatment of bacterial infections and inflammation. It is an organic solution that can be injected, administered orally, or applied topically. The 2-(4-formylphenyl)propionic acid has been shown to have anti-inflammatory properties, but also has side effects such as skin irritation when it is applied topically. This drug can also cause nausea, vomiting, and diarrhea when administered orally.

    Fórmula:C10H10O3
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:178.18 g/mol

    Ref: 3D-IF27430

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  • DL-threo-Ritalinic acid

    Producto controlado
    CAS:

    DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.

    Fórmula:C13H17NO2
    Pureza:Min. 95%
    Peso molecular:219.28 g/mol

    Ref: 3D-IR180350

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  • cis-Tadalafil

    CAS:

    Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

    Fórmula:C22H19N3O4
    Pureza:Min. 95%
    Forma y color:White/Off-White Solid
    Peso molecular:389.4 g/mol

    Ref: 3D-FT27987

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  • (3S,4R)-Tofacitinib

    CAS:

    (3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.

    Fórmula:C16H20N6O
    Pureza:Min. 95%
    Peso molecular:312.37 g/mol

    Ref: 3D-STB57848

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  • 3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride

    CAS:

    3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

    Fórmula:C19H25ClN2O2
    Pureza:Min. 95%
    Peso molecular:348.9 g/mol

    Ref: 3D-WMD18565

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  • Ciprofloxacin ep impurity C

    CAS:

    Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

    Fórmula:C15H16FN3O3
    Pureza:Min. 95%
    Peso molecular:305.30 g/mol

    Ref: 3D-DEA22212

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  • Simvastatin acid

    CAS:

    Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

    Fórmula:C25H40O6
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:436.58 g/mol

    Ref: 3D-IS63828

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  • N-Benzyl albuterol

    CAS:

    N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

    Fórmula:C20H27NO3
    Pureza:Min. 95%
    Peso molecular:329.4 g/mol

    Ref: 3D-ZAA08503

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