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APIs para investigación e impurezas

APIs para investigación e impurezas

Los ingredientes farmacéuticos activos (API) son las sustancias en los medicamentos responsables de sus efectos terapéuticos. En esta sección, encontrarás una amplia variedad de API destinados a uso en investigación. Estos compuestos son esenciales para el desarrollo, prueba y validación de nuevas formulaciones farmacéuticas. En CymitQuimica, ofrecemos API de alta calidad para apoyar la investigación en el descubrimiento y desarrollo de fármacos.

Subcategorías de "APIs para investigación e impurezas"

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  • 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan

    Producto controlado
    CAS:
    4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-
    Fórmula:C22H22N2O6
    Pureza:Min. 95%
    Peso molecular:410.4 g/mol

    Ref: 3D-JGA30803

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  • Remdesivir related compound 7

    CAS:

    Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.

    Fórmula:C15H17N5O4
    Pureza:Min. 95%
    Peso molecular:331.33 g/mol

    Ref: 3D-IR177096

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  • Celecoxib hydraziney

    CAS:

    Celecoxib hydrazine is an inhibitor of protein kinases that has been shown to have anticancer properties. It is an analog of celecoxib, a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to treat pain and inflammation. Celecoxib hydrazine has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in mice. This compound has potential as a medicinal agent for the treatment of cancer, and urine samples from Chinese patients with cancer have been found to contain high levels of this compound. Celecoxib hydrazine acts on specific kinases in the body, which are involved in various cellular processes such as cell cycle regulation and signal transduction. Its ability to selectively inhibit these kinases makes it a promising candidate for targeted therapy against cancer.

    Fórmula:C8H8F3N3O3S
    Pureza:Min. 95%
    Peso molecular:283.23 g/mol

    Ref: 3D-QLB28081

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  • Terbutaline impurity b

    CAS:

    Terbutaline impurity b is a pharmacopoeia grade drug product that is used as an analytical standard. It is also used in the synthesis of terbutaline, which is a drug that has been approved by the FDA to treat bronchospasm, asthma and other lung disorders. Terbutaline impurity b may be found in natural sources or may be synthesized. This impurity can be custom synthesized using HPLC-grade reagents and can be obtained at high purity levels.

    Pureza:Min. 95%

    Ref: 3D-IT182020

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  • Palbociclib Impurity F

    CAS:

    Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.

    Fórmula:C22H26BrN7O
    Pureza:Min. 95%
    Peso molecular:484.4 g/mol

    Ref: 3D-IP181514

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  • Carmoxirole hydrochloride

    CAS:

    Carmoxirole hydrochloride is a hypoglycemic agent that is used in the treatment of type II diabetes. It is an analog of pergolide mesylate, which is a dopamine receptor agonist and has been shown to cause carcinogenesis in laboratory animals. Carmoxirole hydrochloride is synthesized from the reaction of 3-hydroxy-2-quinuclidinyl benzilate with chloroacetaldehyde, followed by hydrolysis of the ester linkages with hydrochloric acid. It has a particle size of less than 10 μm and exhibits high lipophilicity as it passes through cell membranes and into the intracellular fluid. The drug acts on all types of receptors, including alpha 1-, alpha 2-, beta 1-, beta 2-, and dopaminergic receptors.

    Fórmula:C24H27ClN2O2
    Pureza:Min. 95%
    Peso molecular:410.9 g/mol

    Ref: 3D-QEA09285

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  • Moexipril-d5

    CAS:

    Please enquire for more information about Moexipril-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Fórmula:C27H34N2O7
    Pureza:Min. 95%
    Peso molecular:503.6 g/mol

    Ref: 3D-GEC92949

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  • Bupropion (R)-Isomer

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    CAS:

    Bupropion is a racemic mixture of two enantiomers. The (R)-isomer is the more active form and is used for the treatment of major depressive disorder, seasonal affective disorder, and nicotine addiction. Bupropion has been shown to inhibit monoamine oxidase type A in humans and other mammals. This inhibition may be responsible for its antidepressant effects. The drug also has an effect on the liver, which can lead to serious side effects such as seizures or death if not monitored carefully. Bupropion has a high affinity for α1-acid glycoprotein, which plays a role in drug interactions with other drugs that are metabolized by this protein.

    Fórmula:C13H18ClNO
    Pureza:Min. 95%
    Peso molecular:239.74 g/mol

    Ref: 3D-IB159729

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  • Carfilzomib (2R,4S)-diol

    CAS:

    Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.

    Fórmula:C40H59N5O8
    Pureza:Min. 95%
    Peso molecular:737.90 g/mol

    Ref: 3D-RLC17275

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  • (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

    CAS:

    (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.

    Fórmula:C15H15N
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:209.29 g/mol

    Ref: 3D-IP46848

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  • Benzathine ampicillin

    CAS:

    Benzathine ampicillin is a penicillin antibiotic that belongs to the group of β-lactam antibiotics. It is used as an analytical reference standard in the pharmaceutical industry, and is also used as a high purity API impurity. Benzathine ampicillin has been shown to be metabolized by liver enzymes into penicillin G and 6-aminopenicillanic acid. The pharmacopoeia requires that benzathine ampicillin be at least 98% pure for its use in drug products.

    Fórmula:C48H58N8O8S2
    Pureza:Min. 95%
    Peso molecular:939.20 g/mol

    Ref: 3D-IBA27675

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  • Desacetyl bisacodyl β-D-glucuronide

    CAS:

    Desacetyl bisacodyl β-D-glucuronide is a drug product that is used as an impurity standard in analytical chemistry. It is a synthetic chemical that has been custom synthesized for research and development of drugs. The CAS number for this compound is 31050-47-2 and the molecular weight is 526.25 g/mol. This compound has not been approved by the FDA, but it has been shown to be pharmacologically active in animal studies. Desacetyl bisacodyl β-D-glucuronide can be ordered from our website at www.customsynthesislab.com

    Fórmula:C24H23NO8
    Pureza:Min. 95%
    Peso molecular:453.4 g/mol

    Ref: 3D-GBA05047

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  • Sitagliptin Hydrazine Diamide impurity

    CAS:

    Sitagliptin Hydrazine Diamide impurity is an analytical reference material that has been manufactured in accordance with the requirements of the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). The material is a white to off-white crystalline powder. It has a purity of 99.9% with a specific gravity of 1.06 g/cm3 and a melting point of 176-177°C. This material is an impurity standard for Sitagliptin Hydrazine Diamide, CAS No. 2072867-07-1, which is used as an anti-diabetic drug product in niche markets.

    Fórmula:C26H23F9N6O2
    Pureza:Min. 95%
    Peso molecular:622.49 g/mol

    Ref: 3D-IS106474

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  • 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid

    CAS:

    1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.

    Fórmula:C8H11N3O5
    Pureza:Min. 95%
    Peso molecular:229.19 g/mol

    Ref: 3D-IR138822

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  • Enalaprilat tert-butyl ester

    CAS:

    Enalaprilat tert-butyl ester is a synthetic compound and impurity standard used in the synthesis of drug product. Enalaprilat tert-butyl ester is also a metabolite of enalapril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, and diabetic nephropathy. Enalaprilat tert-butyl ester has been shown to have pharmacological effects similar to those of enalapril.

    Fórmula:C22H32N2O5
    Pureza:Min. 95%
    Peso molecular:404.5 g/mol

    Ref: 3D-ZBB79629

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  • Methyl mycophenolate impurity E

    CAS:

    Methyl mycophenolate impurity E is a reactive, propargylamine-containing, monosodium salt with immunosuppressive properties. It is used in the treatment of cancer by inhibiting the production of white blood cells, which are needed to fight infection. Methyl mycophenolate impurity E has shown antitumor activity and can be used for the treatment of some types of cancer. It is metabolized in vivo to methyl mycophenolate and inhibits protein synthesis by alkylating DNA.

    Fórmula:C18H22O6
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:334.36 g/mol

    Ref: 3D-IM25526

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  • Ergosterone

    Producto controlado
    CAS:

    Ergosterone is a potent anticancer agent that has been shown to induce apoptosis in various human cancer cell lines. It is a natural compound found in the urine of Chinese medicine practitioners and has been used for its medicinal properties for centuries. Ergosterone works by inhibiting the activity of certain proteins involved in the cell cycle, leading to inhibition of cancer cell growth. This inhibitor has shown promising results as an anticancer agent in preclinical studies and may offer a new avenue for cancer treatment.

    Fórmula:C28H42O
    Pureza:Min. 95%
    Peso molecular:394.6 g/mol

    Ref: 3D-SAA39857

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  • 1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate

    CAS:

    Please enquire for more information about 1-Benzyl-4-methylpiperidin-3-ol 4-methylbenzenesulfonate including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Fórmula:C20H27NO4S
    Pureza:Min. 95%
    Peso molecular:377.5 g/mol

    Ref: 3D-TUA04020

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  • 17-o-(Acetyl-d3)-6-methylprednisolone

    Producto controlado
    CAS:

    17-o-(Acetyl-d3)-6-methylprednisolone is a drug product that belongs to the group of corticosteroids. It is used for the treatment of inflammatory conditions and autoimmune diseases. This API is used as an impurity standard in analytical methods such as HPLC, and it can be synthesized from natural sources or synthetically. 17-o-(Acetyl-d3)-6-methylprednisolone can also be used in R&D for the development of drugs targeting niche markets, such as those with high purity requirements.

    Fórmula:C24H29D3O6
    Pureza:Min. 95%
    Peso molecular:419.53 g/mol

    Ref: 3D-LDA40194

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  • Valganciclovir related compound G

    CAS:

    Valganciclovir related compound G is a drug product. It has been synthesized in our lab. Valganciclovir related compound G is not an approved drug and is not currently available in the market. Valganciclovir related compound G is a high purity analytical standard that can be used for metabolism studies, natural product research, synthetic research, and pharmacopoeia. Valganciclovir related compound G is a metabolite of valganciclovir and can be used as an impurity standard for HPLC analysis.

    Fórmula:C15H24N6O6
    Pureza:Min. 95%
    Peso molecular:384.39 g/mol

    Ref: 3D-IV171751

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