APIs para investigación e impurezas

<p>4-L-Glutamic Acid]-desmopressin is an analytical standard that is used to calibrate HPLC systems. This product is a high purity, synthetic, and drug development API impurity that can be used as a drug product or impurity standard. It is also available as an HPLC standard, niche, and custom synthesis. 4-L-Glutamic Acid]-desmopressin has been shown to have pharmacopoeia and CAS No.</p>

<p>Medoxomil is a magnetic resonance imaging contrast agent that belongs to the class of organic compounds called tetrazoles. Medoxomil is a white crystalline solid which has a melting point of about 200 degrees Celsius. It has been used as a pharmaceutical intermediate and in the process development of other drugs, such as impurities. Medoxomil is not soluble in water, but can be dissolved in solvents such as acetone or chloroform. The nitrogen atom in this molecule is protonated at physiological pH and interacts with an electron-rich aromatic ring, which leads to its magnetic properties. This compound's X-ray diffraction pattern shows it has a single crystal lattice structure with a space group P2(1). The 1H NMR spectrum indicates that it contains methyl derivatives, while the 13C NMR spectrum reveals that it also contains carbonyl and hydroxyl groups.</p>

<p>Please enquire for more information about (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Descyclopropyl-2-oxopropyl prasugrel is a metabolite of the prodrug prasugrel. It is a synthetic compound that has been shown to have pharmacological activity similar to its parent drug. Descyclopropyl-2-oxopropyl prasugrel has a purity of &gt;98% and is available as an API standard in impurity grade and as custom synthesis. The chemical name for descyclopropyl-2-oxopropyl prasugrel is 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2- yl)butoxy]-N-(3S)-(3aR*,8aS*)-octahydroindole-1,3(2H)-dione.</p>

<p>Tetrahydro erlotinib is a drug product that is used in the treatment of non-small cell lung cancer. Tetrahydro erlotinib is an inhibitor of tyrosine kinases and can act on epidermal growth factor receptors, vascular endothelial growth factor receptors, and platelet-derived growth factor receptors. It has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. Tetrahydro erlotinib is metabolized by CYP3A4 to form two major metabolites, which have similar pharmacological properties as the parent compound. These metabolites are eliminated from the body primarily through urinary excretion. Tetrahydro erlotinib may be toxic to the liver and kidneys due to its ability to induce hepatotoxicity and nephrotoxicity.</p>

<p>Please enquire for more information about Benzilic acid 1-ethyl-3-pyrrolidinyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-(2-Hydroxy-3-isopropylaminopropoxy)benzoic acid 2-hydroxyethyl ester is a synthetic drug product that can be used as an HPLC standard. It has been shown to be metabolized in the rat, with the major metabolites being 2-hydroxyethoxyacetic acid and 4-(2-hydroxyethoxy)benzoic acid. This compound is not found naturally in any living organisms and is not an impurity of any API. The purity of this compound is &gt;98%.</p>

<p>Dv-7028 is a synthetic, natural, and/or semi-synthetic compound that is used in research and development. It can be used as an analytical standard or HPLC standard. Dv-7028 has been shown to inhibit the metabolism of drugs such as coumarin, phenacetin, acetanilide, and antipyrine. It also serves as an impurity standard for the pharmacopoeia. This molecule has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>

<p>7-O-(Triethylsilyl) paclitaxel is a synthetic Taxol analog. It is manufactured by custom synthesis and purified by HPLC to be used as an analytical standard for the determination of natural Taxol impurities in drug products.</p>

<p>2,2',3,3'-Tetrachlorobiphenyl is an inhibitor that has been shown to have anticancer properties. It inhibits the growth of tumor cells by blocking the activity of protein kinases, which are enzymes that regulate cell division and proliferation. This compound has been tested in Chinese hamster ovary cells and has been found to induce apoptosis in cancer cells. Additionally, 2,2',3,3'-Tetrachlorobiphenyl has analog inhibitors that have been tested in human urine samples and have shown potential as anticancer agents. These analogs inhibit cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle. The inhibition of CDKs leads to the suppression of cancer cell growth and division, making this compound a promising candidate for future cancer treatments.</p>

<p>2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.</p>

<p>6,8-Disulfo-2-naphthalenediazonium (6,8-DN) is a Chinese anticancer protein analog that has been shown to induce apoptosis in cancer cells. It is an inhibitor of the antibiotic linezolid and has been found to be effective against various types of human cancer cells. 6,8-DN has been detected in urine samples from patients with tumors and may serve as a potential biomarker for cancer diagnosis. It also acts as a kinase inhibitor, which can affect the regulation of cell growth and division. The inhibition of kinases by 6,8-DN may play a role in its anticancer activity.</p>

<p>3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione is a research and development impurity standard. It is a synthetic drug product with high purity and pharmacopoeia grade. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1 piperidinyl]ethyl]-7,8 dihydro 2 methyl 4 H pyrido [ 1 , 2 - a ] pyrimidine 4 9 ( 6 H ) dione has CAS No. 118951665 1 and is an analytical standard for HPLC analysis. 3-[2-[4-(6 Fluoro 1 , 2 benzisox</p>

<p>Biphenyl-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester is a research and development impurity standard. It is a synthetic compound that can be custom synthesized to meet your needs. The product is available in high purity and pharmacopoeia grade. It has been used as a drug product in studies involving metabolism of the drug. This product has also been used as an analytical standard for HPLC analysis.</p>

<p>(16Beta,17Beta)-16,17-Dihydroxyestr-4-en-3-one is a high purity custom synthesis drug product that is used for metabolism studies. It is also an analytical standard for HPLC and pharmacopoeia standards. This product has been shown to be a natural metabolite of 4-hydroxytestosterone and to have activity similar to testosterone in animal models. (16Beta,17Beta)-16,17-Dihydroxyestr-4-en-3-one is synthesized from estrone by dehydrogenation, reduction of the double bond at C18 and oxidation of the hydroxyl group on C1.</p>

<p>(E)-4-Alloxycarboxyl tamoxifen is a synthetic metabolite of tamoxifen. It is an impurity in the drug product, and can be found in the urine and blood of patients who have taken tamoxifen. The stability of (E)-4-Alloxycarboxyl tamoxifen has been studied by incubating it with rat liver microsomes at 37°C for 30 minutes. Metabolism studies have been done on rats and mice to measure the effect of (E)-4-Alloxycarboxyl tamoxifen on their endogenous levels of estrogen. The pharmacopoeia lists (E)-4-Alloxycarboxyl tamoxifen as a standard for HPLC analysis.</p>

<p>Lamivudine epimer</p>

<p>Nad 299 hydrochloride is a prodrug that is hydrolyzed in vivo to the active drug nadolol. It has been shown to be biodegradable and can be used for diagnostic purposes. Nad 299 hydrochloride is a functionalized molecule with reactive functional groups, which can be conjugated to amino acid sequences or other bioactive molecules. The drug linker contains an aliphatic chain that degrades over time, releasing the active drug. Nadolol is a cardiovascular agent that blocks beta-adrenergic receptors and thus reduces heart rate, cardiac output, and myocardial oxygen demand.</p>

<p>Diethyl methylphenylmalonate is a halogenated organic compound that can be prepared by the reaction of magnesium with diethyl malonate and methylbromide. Diethyl methylphenylmalonate is used as a ligand in coordination chemistry and as a catalyst in organic reactions. The mechanism of this chemical's action is unknown, but it has been shown to be hydrophobic and to bind to microbial cells. It also has been demonstrated to have an oxidation catalyst activity. Diethyl methylphenylmalonate can be synthesized from vitamin b12, piperazine, and solid catalyst irradiation or electrolysis.</p>

<p>4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is a synthetic compound that is used in the development of pharmaceutical drugs. It is used as an analytical standard for HPLC and is available as a new drug product. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol has been shown to be metabolized by CYP 450 enzymes and to be an impurity in API production. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is also found in natural products such as plant leaves and bark.</p>

<p>Tert-butyl β-carboline-3-carboxylate is a GABAergic drug that binds to the benzodiazepine receptor and has been shown to be a nonselective antagonist. The drug has a high affinity for the benzodiazepine receptor, but does not bind selectively to any subunit of the receptor. Tert-butyl β-carboline-3-carboxylate is used in animal models to study depression and anxiety. It increases the release of gamma aminobutyric acid (GABA) in the ventral tegmental area and decreases locomotor activity in wild type mice, but has no effect on these behaviors in mice with a mutation in GABA receptors. In addition, this drug binds competitively to triazolam and blocks its binding site on GABA receptors. Tert-butyl β-carboline-3-carboxylate also inhibits ethanol consumption by wild type mice, but not by mutant mice lacking the</p>

<p>N-Boc-N-desethyl acetildenafil is a synthetic drug product that is used as an analytical standard in metabolite studies. It is also used as an impurity standard for the synthesis of Acetildenafil, which is a drug used to treat erectile dysfunction. N-Boc-N-desethyl acetildenafil has a purity of 99% and can be synthesized in quantities ranging from 1 gram to kilograms. This product's CAS number is 1246820-46-1.br&gt;<br>br&gt;<br>N-Boc-N-desethyl acetildenafil has not been evaluated by the FDA and is not intended for human or veterinary use.</p>

<p>L-Isoleucine orlistat is a drug product that is an analytical standard and a natural product. It is used in research and development for the study of drug metabolism, and as an impurity standard for synthetic L-isoleucine. L-Isoleucine orlistat has CAS number 1072902-75-0 and Impurity Standard Number (ISN) 910.<br>L-Isoleucine orlistat is not a registered active pharmaceutical ingredient (API). It can be custom synthesized to meet the requirements of a particular application, such as high purity, pharmacopoeia grade, or USP HPLC grade.</p>

<p>N-Desmethyltoremifene is an anti-estrogen that has been shown to have genotoxic effects. It inhibits DNA synthesis and protein synthesis in human breast cancer cells. N-Desmethyltoremifene is a potent inducer of CYP3A4, which metabolizes many drugs. This drug also binds to α1-acid glycoprotein, which can lead to reduced plasma concentrations and pharmacokinetics. N-Desmethyltoremifene has been shown to inhibit the growth of renal cell carcinoma in animals, but not normal tissue, at high doses.</p>

<p>Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.</p>

<p>1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile is a fluorescent probe that can be used for the detection of drugs in biological samples. It has been shown to have a high fluorescence intensity and low detection sensitivity, making it suitable for use as a probe for detecting drugs with low concentrations. This probe can also be used to study drug interactions and its concentration–time curve in humans. The drug transporter P-glycoprotein (Pgp) is inhibited by verapamil, which could explain the increase in 1-isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile's detection sensitivity.</p>

<p>Naproxen EP Impurity D is a research and development impurity standard that is used for pharmacopoeia drug product, synthetic, high purity, and analytical purposes. Naproxen EP Impurity D is a metabolite of naproxen and has been shown to be an active form of the drug in animal studies. The CAS number for Naproxen EP Impurity D is 116883-62-6.</p>

<p>Furegrelate is an analytical reference standard for the hydroxylation of 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl[(5S)-tetrahydro-5-methyl-2-furanyl]-methanone. Furegrelate is a synthetic drug product that has been used in pharmacological and toxicological research. It is a metabolite of the drug Furosemide, which is used to treat heart failure and high blood pressure. Furegrelate has also been found as an impurity in the API (active pharmaceutical ingredient) of other drugs such as Carvedilol and Metoprolol.</p>

<p>Salmeterol dimer impurity is a drug product. It is a custom synthesis with high purity. The metabolite of this compound is salmeterol, which is an active ingredient in the asthma medication Serevent (salmeterol xinafoate). Salmeterol dimer impurity has been shown to be a natural metabolite of salmeterol. Salmeterol dimer impurity has also been shown to have anti-inflammatory properties. This compound can be found as an analytical standard for HPLC and used for research and development purposes.</p>

<p>Frovatriptan is a drug used to treat migraine attacks. It belongs to the triptan class of drugs and is used for the acute treatment of migraine with or without aura in adults. Frovatriptan is an agonist at serotonin 5-HT1B and 5-HT1D receptors, which are thought to be involved in headache pain. It has been shown that frovatriptan can provide relief from migraine pain within 2 hours of administration and that the drug can last up to 24 hours. This drug is contraindicated for use in patients who have hepatic impairment or are taking nonsteroidal anti-inflammatory drugs (NSAIDs). The efficacy of frovatriptan has also been shown in clinical trials, where it was found that over 50% of patients had a 50% reduction in headache severity after 2 hours with a median time to onset being 15 minutes.</p>

PBDE 194 is an analog of a kinase inhibitor that has shown potential as an anticancer agent. It has been found to inhibit the activity of kinases, which are enzymes involved in cell signaling pathways that can contribute to cancer growth and proliferation. PBDE 194 has been shown to induce apoptosis, or programmed cell death, in cancer cells. Additionally, it has been found to inhibit the growth of tumor cells in human and Chinese hamster models. This compound may be a promising candidate for the development of novel anticancer drugs. Urine samples have been used to detect protein inhibitors of PBDE 194, which could aid in the identification of patients who may benefit from this treatment.

<p>Hydrolyzed pomalidomide M10 is an impurity standard that is used to generate the typical chromatographic profile of a drug product. It is a metabolite of pomalidomide, which is a chemotherapeutic drug used in the treatment of multiple myeloma. Hydrolyzed pomalidomide M10 has CAS number 918314-45-1 and is a natural or synthetic compound.<br>Hydrolyzed pomalidomide M10 has been shown to be an analytical standard for HPLC methods, as well as being an impurity standard for pharmacopoeia and custom synthesis. The high purity and potency of this compound make it ideal for drug development, research and analysis.</p>

<p>Damulin B is a potent inhibitor of cancer cell growth and proliferation. This protein analog has been shown to induce apoptosis, or programmed cell death, in Chinese hamster ovary (CHO) cells and other cancer cell lines. Damulin B is a promising medicinal compound for the treatment of leukemia and other types of cancer. It works by inhibiting kinase activity, which is essential for tumor growth and survival. Damulin B has also been found in human urine, indicating that it may have potential as a non-invasive diagnostic tool for cancer detection. With its potent anti-cancer properties, Damulin B represents a promising avenue for the development of new cancer therapies.</p>

<p>Sacubitril Impurity 19 is a drug product that is used as an analytical standard for the purity and concentration of sacubitril. It is also used as an impurity in API manufacture. Sacubitril Impurity 19 is a natural metabolite of sacubitril, which is synthesized from the chemical reaction between sacubitril and hydroxypropyl-beta-cyclodextrin. The impurity has been shown to be eliminated through metabolism studies in rats. Sacubitril Impurity 19 can be found at a concentration of up to 0.2% in commercial samples of sacubitril. It may be present at levels up to 10% in medicinal products containing sacubitril.</p>

<p>4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is a drug that has been developed for the treatment of cancer. It is an impurity standard used in HPLC and GC analysis to quantify the concentration of drugs. This compound is a metabolite of the drug carboplatin and can be found in urine as well as other biological fluids. Metabolites are substances produced by metabolism (chemical reactions) in the body. 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can also be found naturally in plants such as ivy or wild parsnip.</p>

<p>N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit</p>

<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>

<p>2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole is a medicinal compound that has shown promising results in cancer research. It works as an inhibitor of cyclin-dependent kinases, which are essential for cancer cell proliferation. This compound induces apoptosis in cancer cells by inhibiting the activity of certain proteins involved in tumor growth. Studies have shown that 2-(Naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole analogs have potent anticancer activity and can inhibit the growth of human cancer cells. This compound has also been found to be present in urine samples from Chinese patients with cancer. Further research on this compound may lead to the development of new and effective treatments for various types of cancers.</p>

<p>Please enquire for more information about 3-(Acetyloxy)octanedioic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rosuvastatin is a natural, synthetic and semi-synthetic drug product. It is the active ingredient in an investigational drug called Iressa. Rosuvastatin is also known as a cholesterol-lowering agent and belongs to the class of statins. Rosuvastatin inhibits HMG-CoA reductase, an enzyme responsible for synthesizing cholesterol from acetyl CoA. The isoamyl ester form has been shown to have a high degree of stability in human plasma. This product is available as an analytical standard that can be used to generate reference values for metabolism studies or pharmacopoeia (e.g., USP).</p>

<p>(E,E)-Farnesyl thioacetate is a synthetic impurity found in the drug product. It is an impurity standard for HPLC and GC-MS analysis of Metabolism studies. (E,E)-Farnesyl thioacetate is also used as a synthetic intermediate in the synthesis of other compounds. The purity of this compound is 99% with a CAS number 340701-35-1. (E,E)-Farnesyl thioacetate has been synthesized according to pharmacopoeia standards with high purity.</p>

<p>Neostigmine impurity A is a potent inhibitor of kinases that have been implicated in cancer cell growth and tumor progression. It is an analog of cyclin-dependent kinase inhibitors and has shown anticancer activity in human cancer cell lines. Neostigmine impurity A has been isolated from Chinese urine samples and has been shown to induce apoptosis in cancer cells. This compound has the potential to be used as a therapeutic inhibitor for the treatment of cancer. Its mechanism of action involves the inhibition of protein kinases, which are responsible for regulating many cellular processes, including cell division and proliferation. Overall, Neostigmine impurity A is a promising compound for the development of novel cancer therapies.</p>

<p>MMPI-1154 is an analog of a protein kinase inhibitor that has shown promising anticancer activity. It has been found to be effective against various types of cancer cells, including leukemia cells. MMPI-1154 works by inducing apoptosis, or programmed cell death, in cancer cells. It inhibits the activity of certain kinases that are involved in the growth and survival of cancer cells. This inhibitor has been isolated from urine samples of Chinese medicinal plants and shows potential as a tumor growth inhibitor in humans. MMPI-1154 is a promising new class of anticancer drugs that may offer hope for those suffering from cancer.</p>

<p>2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.<br>2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antif</p>

Please enquire for more information about Desamino-hydroxy revefenacin including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Tetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.</p>

<p>4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is an analog of a potent anticancer drug that targets kinases involved in cancer cell growth and survival. This compound has been shown to inhibit the activity of several kinases, including those involved in tumor development and progression. In vitro studies have demonstrated that this inhibitor induces apoptosis in human cancer cells and can inhibit tumor growth in animal models. It has also been found to be effective against Chinese hamster ovary cells and may have potential as a medicinal agent for the treatment of various types of cancer. Overall, 4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is a promising new inhibitor with potential applications in cancer therapy.</p>

<p>Amlodipine besilate impurity D oxalate salt is a pharmaceutical ingredient that is an impurity in Amlodipine besilate and is used as a diluent. It has been shown to have a particle size of less than 10 microns, which makes it suitable for use in tablets. This product is stable at room temperature and does not require refrigeration. It also contains excipients including silicon dioxide and magnesium stearate, which are added to reduce the rate of crystallization and aid flowability.</p>

<p>9-Cis,13-cis-retinol 15-acetate is an impurity in drugs that are used to treat a variety of conditions including psoriasis, acne, and ichthyosis. It has been identified as an impurity in the drug product 9-cis, 13-cis retinoic acid (9CRA) through high performance liquid chromatography (HPLC). It has been found to be a metabolite of 9CRA and is not toxic.</p>

<p>Please enquire for more information about 2-Amino-5-(2-bromoacetyl)benzonitrile hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Azoxystrobin acid is a natural product that is used as an analytical reference material and as an impurity standard. Azoxystrobin acid is synthesized by the reaction of azoxystrobin with acetic anhydride in the presence of triethylamine. The pure compound is obtained by recrystallization from methanol-water. Azoxystrobin acid has been shown to inhibit the growth of bacteria and fungi, and can be used for the treatment of infections caused by these microorganisms. Azoxystrobin acid also inhibits protein synthesis by binding to bacterial ribosomes. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>Torasemide Impurity E is a drug product that belongs to the group of impurities. It is a natural product and can be found in the environment. Torasemide Impurity E has been shown to inhibit bacterial growth in vitro and also antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus. Torasemide Impurity E has been shown to have no cytotoxic effects on human erythrocytes.</p>

<p>Please enquire for more information about 5-Chloro-3-(piperazin-1-yl)benzol[D]isothiazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hydroxyziprasidone is a hydroxy derivative of ziprasidone. It has low levels of impurities and is used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Hydroxyziprasidone is metabolized to ziprasidone in the liver by the cytochrome P450 enzyme system. The main metabolites are 2-hydroxyziprasidone and 4-hydroxyziprasidone. These metabolites are excreted from the body in urine or bile, or they may be further metabolized to other compounds that are eventually excreted as well.</p>

<p>Please enquire for more information about Desethylcarbamoyl cabergoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Haloperidol decanoate EP impurity J hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pronethalol is a non-steroidal anti-inflammatory drug (NSAID) that has been shown to be effective against primary sclerosing cholangitis and chronic inflammatory bowel disease. It is a prodrug that is converted into its active form by the liver, which inhibits the production of prostaglandin E2. Pronethalol may also have cardiac effects, such as increasing blood pressure, but this effect is not permanent. The diagnosis of primary sclerosing cholangitis can be confirmed with an increase in natriuretic peptide levels and high values for fluorescence detector. Long-term efficacy of pronethalol has been demonstrated in some cases. The pyrazole ring on the molecule is a key component for its activity as a drug, and it is a substrate for polymerase chain reaction (PCR).</p>

<p>Arbidol is a drug molecule that interacts with protease enzymes. It has been shown to inhibit human erythrocyte chymotrypsin, trypsin, and elastase. Arbidol is also able to inhibit the growth of bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The molecular modelling of arbidol suggests that it binds to the active site of the enzyme by blocking hydrophobic pockets on the surface of the enzyme. The conformational change in the protease enzyme activates arbidol's binding site for an extended period of time. This prolonged interaction prevents substrate from binding to the catalytic site of the enzyme and inhibits its activity.</p>

<p>ML604440 is a potent inhibitor of cyclin-dependent kinases (CDKs) and has shown anti-cancer activity in various human cancer cell lines. This Chinese analog has been found to inhibit the growth and proliferation of tumor cells by inducing apoptosis. ML604440 works by binding to the ATP-binding pocket of CDKs, preventing their activation and inhibiting downstream signaling pathways involved in cell cycle progression. It also inhibits other protein kinases, including Aurora kinase A and B, which are involved in mitosis. ML604440 has potential as an anticancer agent due to its ability to selectively target cancer cells while sparing normal cells. It is excreted primarily in urine and can be used as a tool compound for studying CDK inhibition and cancer therapeutics.</p>

<p>Secologanin acetal is a lonicerae japonicae schisandrae fruit extract that is used in traditional Chinese medicines. It has been shown to have anti-inflammatory, anti-tumor, and antiviral activities. Secologanin acetal inhibits the production of nitric oxide and pro-inflammatory cytokines in polymorphonuclear cells (PMNs) by inhibiting the activation of NF-κB. Structural formula:</p>

<p>Fluorometholone impurity 5 is a drug product that has been custom synthesized. It has not yet been assigned to a CAS number. This compound exhibits high purity and is an analytical grade. Metabolism studies have been conducted on this substance, which is natural and can be found in the drug development phase. This impurity standard is for HPLC analysis and research and development purposes only.</p>

<p>9-Demethyl FR-901235 is a synthetic compound that is used as an impurity standard for the synthesis of drugs. It is not intended to have any pharmacological activity, and the only known metabolic pathway is through hydrolysis in the liver by esterases. 9-Demethyl FR-901235 has been shown to be a metabolite of FR-900520, and it has been used in metabolism studies. The substance has been identified as an analytical standard for HPLC analysis.</p>

<p>(-)-N,N-Bisdesmethyl tramadol is a potent inhibitor of apoptosis, which plays a key role in the development and progression of cancer. It is an analog of tramadol and has been shown to inhibit the growth of human cancer cells by blocking protein kinase activity. This drug has also been found to be effective against tumors in animal models. (-)-N,N-Bisdesmethyl tramadol is excreted in urine and has been identified as a potential biomarker for anticancer therapy. Studies have shown that this compound can enhance the therapeutic effects of polysaccharides and adenosine inhibitors in Chinese medicine, making it a promising candidate for future cancer treatment research.</p>

<p>Please enquire for more information about 2-[(2-Cyclopentylphenoxy)methyl]-oxirane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pf9 tetrasodium is a high purity, HPLC standard. It is used as an analytical standard in metabolism studies and as a synthetic impurity standard. Pf9 tetrasodium is also used in drug development research and development to create new drugs and to optimize the production of existing drugs. This product is sold in quantities of 100 grams or more. Pf9 tetrasodium has CAS number 851265-78-6.</p>

<p>Epinephrine sulfonic acid-d3 is a synthetic, high purity, pharmacopoeia, drug development, analytical standard. It is used as an impurity standard, and in the synthesis of epinephrine sulfone. Epinephrine sulfonic acid-d3 has been shown to be a metabolite of epinephrine and its metabolites. This product has been synthesized and characterized by HPLC analysis using an ion-pairing agent and a gradient elution with water:acetonitrile (0.1% formic acid) (75:25).</p>

<p>Erythromycin EP impurity L is a metabolite of erythromycin that is found in the urine of patients taking erythromycin. It is a white to light yellow crystalline powder. Erythromycin EP impurity L has been used as an analytical standard for HPLC and GC-MS, and as a pharmacopoeia reference material. Erythromycin EP impurity L is also known to have anti-inflammatory properties.</p>

<p>Please enquire for more information about Daunorubicin EP impurity B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Oxybutynin impurity C is a metabolite of the drug product Oxybutynin (CAS No. 1199574-70-3). It is an analytical standard for HPLC, and a natural impurity in the synthesis of Oxybutynin. This is a synthetic compound that has been shown to be metabolized through oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Oxybutynin impurity C has been used as an analytical reference material for drug development and research and development.</p>

<p>Fluticasone furoate is a synthetic corticosteroid that has anti-inflammatory and immunosuppressive properties. It binds to the glucocorticoid receptor, which inhibits the production of inflammatory cytokines and mediators. The impurity standard used in this product is Fluticasone furoate EP impurity G. This impurity is a metabolite of fluticasone furoate with a molecular weight of 488. It has been shown that this impurity may have an effect on the pharmacokinetics of fluticasone furoate.</p>

<p>Gomphrenin I is an analog of a human protein that has been found to have potent anticancer properties. It works by inhibiting kinases, which are enzymes involved in cell signaling pathways that can contribute to the growth and survival of cancer cells. Gomphrenin I has been shown to induce apoptosis, or programmed cell death, in cancer cells and has demonstrated efficacy against various tumor types. This medicinal compound is a promising inhibitor for kinases and may hold potential as a therapeutic agent for cancer treatment. Gomphrenin I has been isolated from Chinese herbal medicine and can be detected in urine samples after ingestion.</p>

<p>(5aR,10aR)-Tetrahydro-3H,5H,8H,10H-bisthiazolo[3,4-a:3',4'-d]pyrazine-5,10-dione is a drug product that is an impurity standard for the API (Active Pharmaceutical Ingredient) 5α-tetrahydrospiro[benzofuran-1(3H),2'(3'H)]pyrido-[2,1'-cyclohexan]-6β,7β-(1'H)-dione. It is a metabolite of this API and can be used as a research and development analytical standard for HPLC. The CAS number for this compound is 72744-67-3. This substance has been found in natural products such as the seeds of Sesamum indicum L., Cucurbita maxima Duchesne var.</p>

<p>Fensulfothion oxon sulfide is a drug product that can be used as an analytical reference material. It has been shown to be metabolized in animal studies. The metabolite, fensulfothion sulfoxide, can be synthesized from fensulfothion oxon sulfide and is a standard impurity in the synthetic process. Fensulfothion oxon sulfide is used in drug development and research and development to establish pharmacopoeia standards for HPLC purity requirement.</p>

<p>Ambrisentan is a drug product that is used in the treatment of pulmonary hypertension. Ambrisentan is metabolized to ambrisentan acyl β-D-glucuronide, a natural metabolite that has been synthesized as an analytical standard. It also shows antihypertensive activity and is currently under development for use in the treatment of heart failure.</p>

<p>Please enquire for more information about 1,4-Bis(trichloromethyl)-2,5-dichlorobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Desmethyl 3-hydroxy mepivacaine is a metabolite of mepivacaine. It has been shown to be effective in the treatment of chronic pain and postoperative pain. N-Desmethyl 3-hydroxy mepivacaine is also used as an impurity standard for pharmaceuticals. The CAS number for this product is 247061-17-2. This product is available for custom synthesis and can be found in the pharmacopoeia.</p>

<p>23,24-Anhydro tacrolimus is a synthetic prodrug of the immunosuppressant drug tacrolimus. It has the same pharmacological effects as the parent compound and can be used in its place to avoid adverse reactions. The metabolite of 23,24-anhydro tacrolimus is a natural metabolite of tacrolimus and has been synthesized for research purposes or for use as an analytical standard. 23,24-Anhydro tacrolimus is not an impurity standard, but rather a niche product that is not commercially available from suppliers.</p>

<p>Please enquire for more information about 2-[4-(Dimethylamino)-1-(2-methylphenyl)butyl]-phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Amoxicillin EP Impurity G is an impurity of Amoxicillin. It is a white to off-white crystalline powder with a melting point of 178 °C. The compound is soluble in alcohol, chloroform, ether, and acetone. This product can be used as an analytical standard for the drug development, niche drug product, or custom synthesis of the drug. Impurity G has been shown to have pharmacopoeia purity and natural origin. It can also be used as an impurity standard for HPLC analysis and pharmaceutical testing.</p>

<p>(R)-3-Quinuclidinyl di(2-thienyl)glycolate is a Chinese-made inhibitor that targets kinases in tumor cells. It has shown promising results as an anticancer agent, inducing apoptosis in cancer cells. This compound has been studied in combination with other drugs such as chloroquine and artesunate, which have also shown anticancer properties. (R)-3-Quinuclidinyl di(2-thienyl)glycolate is excreted through urine and has been found to be effective against various types of human cancers. It acts as an analog of kinase inhibitors and shows potential for further development in the field of cancer treatment.</p>

<p>Fosfomycin trometamol EP impurity A disodium is a research and development impurity standard. It is a custom synthesis that is used as a drug product, synthetic, high purity, pharmacopoeia, drug development, metabolite, niche, analytical and natural. Fosfomycin trometamol EP impurity A disodium has been shown to have an HPLC standard and CAS No. 84954-80-3(free base).</p>

<p>Please enquire for more information about 3,4-Difluoro-2-(trifluoromethyl)-benzenamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ivacaftor is a drug product that is used for the treatment of cystic fibrosis. It is an active ingredient of Kalydeco, which is a combination therapy to treat cystic fibrosis. Ivacaftor is the first FDA-approved drug for the treatment of CF in patients with specific mutations. The metabolism of ivacaftor has been studied by analytical methods and it has been shown to have natural impurities. The API impurity and synthetic impurity standards are available for custom synthesis and can be ordered from a specialty manufacturer. Ivacaftor requires high purity and pharmacopoeia-grade standards for research and development as well as niche markets, such as HPLC standard or high purity.</p>

<p>Prizidilol is a medicinal inhibitor that has shown promising results as an anticancer agent. It works by inhibiting protein kinases, which are enzymes involved in cell cycle regulation and apoptosis. Prizidilol has been found to be effective against cancer cells in both Chinese hamster and human urine tumor models. This inhibitor has also been shown to have potential as an analog for other inhibitors used in cancer research. Its ability to induce apoptosis in cancer cells makes it a promising candidate for future cancer therapies.</p>

<p>Raltegravir is a drug that inhibits HIV-1 protease. It is an analytical standard for HPLC, and can be used in the development of drugs, including as an impurity standard. Raltegravir has shown promising results in clinical trials, but it is not available commercially. The chemical compound 2-des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-amino-2-oxoacetic acid) raltegravir has CAS No. 1064706-98-4 and is a natural product.</p>

<p>2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic acid is a metabolite of the plasticiser diethyl phthalate. It is found in urine samples and can be quantified by liquid chromatography with electrospray ionization mass spectrometry. 2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic acid has been shown to cause cancer in animals and newborns, as well as to inhibit male reproductive development in humans. This compound can be detected in the population at a dilution of 1:100,000.</p>

<p>Griseofulvic acid is a molecule that encompasses an acidic chromatographic and plasma samples, urine metabolite, monocarboxylic acid, water molecule, pharmaceutical preparations, molecule, cancer and hyperproliferative. Griseofulvic acid is used for the treatment of autoimmune diseases and cancers. In addition to its use as an anticancer drug, griseofulvic acid has been shown to have immunosuppressive effects in cell cultures. The mechanism of action of griseofulvic acid in this regard may be due to its ability to disrupt DNA synthesis by binding to the purine bases in RNA and DNA molecules.</p>

<p>2-(((4-Methyl-7-oxyooctyl)oxy)carbonyl)cyclohexanecarboxylic acid (2MEOCA) is a metabolite of progesterone which has been detected in human urine. 2MEOCA can be found in the environment as a result of industrial production or from the use of materials containing progesterone in consumer products, such as plastics and personal care products. It has been postulated that 2MEOCA may be an analytical biomarker for exposure to progesterone and its metabolites.<br>2MEOCA is stable in urine samples stored at room temperature for at least 24 hours and can be measured by a high performance liquid chromatography - mass spectrometry (HPLC-MS/MS) method. The median concentration of 2MEOCA was found to be 0.3 ng/mL in on-line pooled human urine samples, with concentrations ranging from 0.1 ng/mL</p>

<p>Nascopine is an analog of nifedipine that acts as a potent inhibitor of protein kinases. It has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in Chinese hamsters. Nascopine is an anticancer drug that works by blocking the activity of kinases, which play a crucial role in cancer cell proliferation and survival. This drug has been found to be effective against a wide range of cancers, including breast, prostate, and lung cancer. In addition, Nascopine has been found in urine samples from cancer patients undergoing treatment with this drug. Its unique mechanism of action makes it a promising candidate for further development as an anticancer therapy.</p>