APIs para investigación e impurezas

<p>Please enquire for more information about 2′,4′′-Bis-O-(trimethylsilyl)-erythromycin 9-[O-(1-ethoxy-1-methylethyl)oxime] including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ergoline-8β-carboxylic acid methyl ester hydrochloride is a drug product that has been developed for research and development. It is an analytical standard, impurity standard, and HPLC standard. Ergoline-8β-carboxylic acid methyl ester hydrochloride is a metabolite of ergometrine, which is an ergot alkaloid with pharmacological properties similar to those of ergonovine. Ergoline-8β-carboxylic acid methyl ester hydrochloride is used as an impurity in the synthesis of ergometrine. The purity of this compound meets the requirements of pharmacopoeia standards for use as an analytical reference substance.</p>

<p>Please enquire for more information about Cephalexin diketopiperazine monoacid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ibudilast-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Baclofen inhouse impurity is an analog of baclofen that has been shown to have potent anticancer properties. It acts as a kinase inhibitor, specifically inhibiting the activity of certain kinases that are involved in cancer cell growth and proliferation. In preclinical studies, this compound has demonstrated significant tumor growth inhibition and induction of apoptosis in human cancer cell lines. This medicinal compound is commonly used in Chinese medicine for its anti-cancer effects. Baclofen inhouse impurity can be isolated from urine or synthesized chemically. Its potential as a protein kinase inhibitor makes it a promising candidate for further development as an anticancer agent.</p>

<p>Please enquire for more information about (-)-OSU-d7 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Di(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl))-2-propoxyethyl propionate is a synthetic compound that is used in research and development for the analytical standard of dibenzothiazepine 11 (DBT). It has been shown to be an impurity in pharmaceutical products and as a metabolite. Di(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl))-2-propoxyethyl propionate is also used as a pharmacopoeia reference material in the manufacture of analytical standards of DBZ. CAS No. 1798840-31-9</p>

<p>Please enquire for more information about Rosuvastatin impurity 42 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (5α,25R)-26-Hydroxycholestan-3-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N,N-Bis(2-chloroethyl)-4-methoxybenzenesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>BGC-20-1531 is a medicinal compound that has been found to be an effective inhibitor of kinases in cancer cells. This Chinese-derived analog has shown potent anticancer activity in human tumor models and induces apoptosis in cancer cells. It works by inhibiting the protein kinase activity that is essential for cancer cell survival, leading to cell death. BGC-20-1531 has been shown to be effective against a wide range of cancer types and can be used as a potential therapeutic agent for cancer treatment. Additionally, this compound has been found in human urine and may have potential as a biomarker for cancer diagnosis and prognosis. With its unique characteristics, BGC-20-1531 is an exciting new prospect for the development of novel anticancer drugs.</p>

<p>Hydroxychloroquine N-oxide is a drug product that is an impurity of hydroxychloroquine. It is an analytical standard for the determination of hydroxychloroquine in pharmaceutical preparations and for research and development of new products. Hydroxychloroquine N-oxide is also used as an impurity standard for HPLC with UV detection, LC/MS, and GC/MS. The chemical formula of this compound is C6H7ClN3O4. The molecular weight of this compound is 231.09 g/mol. Hydroxychloroquine N-oxide has CAS No. 1449223-88-4 and natural status. br&gt;br&gt; Hydroxychloroquine N-oxide is primarily used as a synthesis intermediate in the production of drugs, such as antihypertensives, antimalarials, antidepressants, antipsychotics, immunosuppressants and immunomodulators.br&gt;br&gt; The</p>

<p>2,6-Dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid monomethyl ester is a metabolite of the drug 2,6-dimethyl-4-(3-nitrophenyl)pyridine. It has been shown to have an analytical purity greater than 98%. This compound is marketed as an HPLC standard and can be used as an impurity standard in the manufacture of a drug product. The CAS number for this compound is 64603-72-1.</p>

<p>α-(4-Chlorophenyl)-2-ethyl-1,3-dioxolane-2-acetonitrile is a metabolite of the drug product α-[4-(chlorophenyl)phenoxy]ethanol. It has been used as an impurity standard for HPLC and as a pharmacopoeia.<br>!--</p>

<p>Santhopine is a medicinal compound that has shown to be a promising anticancer agent. It is a kinase inhibitor that targets various protein kinases involved in cancer cell proliferation and survival. Santhopine has been found in the urine of Chinese cancer patients and has been shown to induce apoptosis (programmed cell death) in human cancer cells. This compound inhibits the cell cycle, preventing the uncontrolled growth of tumor cells. Santhopine's potential as an anticancer drug makes it an exciting area of research for cancer treatment.</p>

<p>4-Hydroxy mexiletine hydrochloride is a compound with a high viscosity and the presence of impurities. It forms hydrogen bonds and has been found to interact with growth factors such as epidermal growth factor (EGF). This compound has been shown to have neutralizing effects on CDK4/6 inhibitors like palbociclib, which are commonly used in cancer treatment. Additionally, 4-Hydroxy mexiletine hydrochloride binds to proteins involved in cellular processes, such as interleukin-6 (IL-6) and monoclonal antibodies. Its structure includes a chelate ring, which can be observed in its mass spectrum analysis. Furthermore, this compound has demonstrated an impact on hepatocyte growth and phycocyanin.</p>

<p>Fluticasone furoate impurity K is a synthetic drug product that is used in the manufacture of pharmaceutical products. It has a CAS Number of 220589-37-7, and the purity of the compound is &gt;98%. The compound has been synthesized using natural starting materials, and it has undergone metabolism studies to determine its pharmacological activity. Fluticasone furoate impurity K is on the list of substances that are not scheduled by the US DEA. Fluticasone furoate impurity K is an analytical standard and Metabolite for use in HPLC analysis. Fluticasone furoate impurity K can be used as a Research and Development or Pharmacopoeia standard. This compound may also be useful for niche applications such as Drug development or Custom synthesis.</p>

<p>NMP-ACA is a metabolite of cefepime. It is a synthetic, impurity standard for use in HPLC. It has an analytical purity of &gt;98%. The metabolites of NMP-ACA are not known at this time.</p>

<p>Desoximetasone impurity A is an impurity found in the drug product Desoximetasone, which is a corticosteroid. It has been identified as an impurity in the drug product and there are no known uses of Desoximetasone impurity A. This impurity was determined to be natural based on its molecular weight, infrared spectrum, melting point, and elemental analysis. The molecular weight for Desoximetasone impurity A is 687.2 g/mol with a melting point at 89°C and an elemental analysis of Carbon: 29%, Hydrogen: 3%, Nitrogen: 16%, Oxygen: 32%.</p>

<p>4-Methanesulfonyloxybutanol is a chemical substance with the molecular formula CH3SO2CH(CH2OH)CH2OH. It is used as an intermediate in the synthesis of 4-methanesulfonyloxybutanol, which is a potent inhibitor of busulfan-induced leukopenia and myelosuppression. This substance has been shown to be highly effective in preventing busulfan-induced side effects when administered intravenously. 4-Methanesulfonyloxybutanol is chemically synthesized by intramolecular alkylation of butanol, followed by hydrolysis. The reaction product can be detected using an ionization detector in conjunction with gas chromatography. This product is an alkylation agent that reacts with polypropylene to produce polypropylene glycols.</p>

<p>1,2,3,4-Tetrahydro-4,6,7-isoquinolinetriol hydrochloride is a drug product. It is a synthetic compound that is metabolized to form metabolites. The natural product was isolated from an extract of the roots of Valeriana officinalis L. and has been used as a sedative and hypnotic in traditional medicine. 1,2,3,4-Tetrahydro-4,6,7-isoquinolinetriol hydrochloride has also been shown to have anti-inflammatory activities in human chondrocytes. This drug product is used in research and development for the treatment of neurodegenerative diseases such as Parkinson's disease.</p>

<p>2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole (CAS No. 168167-42-8) is a synthetic compound that is used as an analytical reference standard for HPLC. It is also used in the study of drug metabolism, and it has been shown to induce natural oxidation in vitro. 2-[(4-Chloro-3-methylpyridinium)methylsulfinyl]-1Hbenzimidazole is an impurity found in pharmaceutical products that are synthesized from 1-(2,4,6trichlorophenyl)-3-[(4chloromethyl)phenyl]urea.</p>

<p>Remdesivir impurity 8 is a metabolite of remdesivir, a drug product that belongs to the class of synthetic compounds. Remdesivir impurity 8 has been used as a research and development standard for HPLC analysis. It is also used as an impurity standard in pharmacopoeia and drug development. This impurity has shown natural activity in metabolism studies, but it is not known if this activity is due to the compound itself or an artifact from its synthesis.</p>

<p>The ethylene terephthalate cyclic pentamer is a polyester that is used in the manufacture of polyester fibers and polyester films. It is extracted from the raw material, which is a mixture of dimethyl terephthalate, ethylene glycol, and 1,4-butanediol. The extruder heats the raw material to 240°C in order to convert it into its liquid form. The crystallization process takes place at room temperature and produces a white solid product called oligomer. Extraction removes impurities from the oligomer by washing it with water. Linear polyester is obtained by heating the purified oligomer at 260°C for 40 minutes, while extruded polyester undergoes a heat treatment of 230°C for 20 minutes. Extrusion produces pellets that are then processed into filaments or sheets.</p>

<p>Please enquire for more information about 3,4-Di-o-benzyl droxidopa-13C2,15N hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sulfo-Cy 3 carboxylic acid is a synthetic fluorescent dye that emits green light and has a fluorescence quantum yield of 0.7. It is prepared via the reaction of benzindole with 4-sulfonyl chloride in the presence of triethylamine and recrystallization from ethyl acetate. The emission wavelength can be tuned by varying the substituents on the indole ring, and it is stable with water solubility.</p>

<p>Quetiapine ep impurity J is a drug product that is custom synthesized to meet the needs of our clients. It can be used for analytical or metabolite identification purposes, as well as research and development. Quetiapine ep impurity J is a metabolite of quetiapine, which is a drug product that falls under the CAS No. 2250242-46-5. We offer high purity and analytical standards for this product and can provide a Metabolism studies report on request. Quetiapine ep impurity J is not listed in the pharmacopoeia and can only be obtained through synthesis. This product also has niche applications in synthetic chemistry research, as well as HPLC standards available on request.</p>

<p>Please enquire for more information about Thromboxane A2 potassium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5'-S-(4-Hydroxybutyl)-5'-thio-adenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Naltrexone Impurity G is a synthetic impurity found in naltrexone. It is used as an impurity standard and can be custom synthesized to meet the needs of researchers, developers, and manufacturers of drug products. Naltrexone Impurity G is a metabolite that has been shown to have pharmacological effects similar to those of naltrexone. It is used in metabolism studies. Naltrexone Impurity G has a purity level of 99% or higher and can be ordered as a methanol solution or powder.</p>

<p>(trans)-4-Propyl-1-methyl-L-proline is a synthetic compound that has been used in the past as an impurity standard in the synthesis of several drugs, including metaxalone and aminopyrine. It is also found to have pharmacological effects on its own and was used as a drug product for the treatment of rheumatoid arthritis. (trans)-4-Propyl-1-methyl-L-proline is not listed in any pharmacopoeia or international list of approved drugs.</p>

<p>Methisosildenafil is a chemical compound that belongs to the group of phosphodiesterase type-5 inhibitors. It is an analog of sildenafil and is used for the treatment of erectile dysfunction (ED). Methisosildenafil has been shown to be effective in animal models of pulmonary hypertension. It also inhibits the production of myeloid-derived suppressor cells, which are responsible for suppressing the immune system. Methisosildenafil has been found to be safe and well-tolerated for use as a pharmaceutical preparation in humans.</p>

<p>Please enquire for more information about (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Descyclopropyl-2-oxopropyl prasugrel is a metabolite of the prodrug prasugrel. It is a synthetic compound that has been shown to have pharmacological activity similar to its parent drug. Descyclopropyl-2-oxopropyl prasugrel has a purity of &gt;98% and is available as an API standard in impurity grade and as custom synthesis. The chemical name for descyclopropyl-2-oxopropyl prasugrel is 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2- yl)butoxy]-N-(3S)-(3aR*,8aS*)-octahydroindole-1,3(2H)-dione.</p>

<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>

<p>Alverine EP Impurity C is a by-product of the synthesis of alverine, which is an ammonium salt. The process involves the use of high yield, high purity triflic acid, and organic solvents. The reaction system is typically carried out in a solvent such as toluene or dichloromethane. The organic solvent is then removed by filtration and the desired product can be obtained by crystallization or recrystallization. Alverine EP Impurity C has been shown to have insecticidal properties when applied externally, due to its interaction with insect stereoisomers. It also has anticancer activity and may be used in cancer therapy treatments that involve decompressing tumours and increasing blood supply to the area. Alverine EP Impurity C also has a citric acid binding property that makes it insoluble in water.</p>

<p>2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a drug product that is used as an analytical reference standard for the metabolism studies of acetaminophen. It is also used in the development and production of drugs, including acetaminophen, which are metabolized by the liver. 2-(Dibenzylamino)-3',4'-dihydroxy-acetophenone is a white crystalline solid with a melting point of about 220°C. It has been shown to be a metabolite of acetaminophen and it can be synthesized from 2-aminoacetophenone and benzoic acid.</p>

<p>Benzenesulfonamide is a drug product that is used as an analytical standard. It is a synthetic drug that has been shown to be metabolized by the liver, forming metabolites such as hydroxybenzenesulfonamide and sulfamethoxazole. Benzenesulfonamide is not under any pharmacopoeia guidelines or regulations. The CAS number for this drug product is 20778-16-9.</p>

<p>Abacavir is an antiviral drug that is used to treat HIV/AIDS. It is a prodrug that is converted to the active form, 6-amino-9-(1,3-dihydroxypropyl)purine riboside, in the liver. Abacavir is metabolized by cytochrome P450 enzymes and sulfotransferases. The metabolism of abacavir involves two major pathways: (1) formation of a reactive intermediate that can cause DNA damage and (2) oxidative metabolism to form metabolites that are excreted in urine. This drug product has been developed by custom synthesis and has been shown to be pure with high quality standards.</p>

<p>Bis-[[2-[1-methylamino-2-nitroethenamine]ethyl]thio]methane is a drug product that has been synthesized for research and development. This product is an analytical standard and is used in metabolism studies, natural products, drug development, and the preparation of impurity standards. The CAS number for this product is 1331637-48-9. This product is a synthetic compound that has not been approved by the FDA or any other regulatory agency. It can be shipped to US destinations only.</p>

<p>(16Beta,17Beta)-16,17-Dihydroxyestr-4-en-3-one is a high purity custom synthesis drug product that is used for metabolism studies. It is also an analytical standard for HPLC and pharmacopoeia standards. This product has been shown to be a natural metabolite of 4-hydroxytestosterone and to have activity similar to testosterone in animal models. (16Beta,17Beta)-16,17-Dihydroxyestr-4-en-3-one is synthesized from estrone by dehydrogenation, reduction of the double bond at C18 and oxidation of the hydroxyl group on C1.</p>

<p>(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.</p>

<p>4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is a synthetic compound that is used in the development of pharmaceutical drugs. It is used as an analytical standard for HPLC and is available as a new drug product. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol has been shown to be metabolized by CYP 450 enzymes and to be an impurity in API production. 4,4-(1,3,3-Trimethyl-1-propene-1,3-diyl)bisphenol is also found in natural products such as plant leaves and bark.</p>

<p>N,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride (DMAEA) is a drug that is used as an ophthalmic. It has been shown to be safe and effective in patients with chronic open angle glaucoma, and it may also have some efficacy for the treatment of other conditions such as uveitis and retinal detachment. DMAEA is thought to work by binding to the DNA in the eye’s optic nerve cells and blocking the production of leukotrienes. This drug has also been shown to have anti-inflammatory properties.</p>

<p>Hydrolyzed pomalidomide M10 is an impurity standard that is used to generate the typical chromatographic profile of a drug product. It is a metabolite of pomalidomide, which is a chemotherapeutic drug used in the treatment of multiple myeloma. Hydrolyzed pomalidomide M10 has CAS number 918314-45-1 and is a natural or synthetic compound.<br>Hydrolyzed pomalidomide M10 has been shown to be an analytical standard for HPLC methods, as well as being an impurity standard for pharmacopoeia and custom synthesis. The high purity and potency of this compound make it ideal for drug development, research and analysis.</p>

<p>Taxol is a natural product that can be found in the bark of the Pacific yew tree. It has been shown to have synergistic effects with 5-HT2A receptor antagonists, such as gamma-aminobutyric acid (GABA) and 5-hydroxytryptamine (5-HT). Taxol has been used in the treatment of cancer, specifically breast cancer. In addition, it has been shown to have an effect on cardiac function by interfering with neurotransmission. This drug also blocks 5-HT2C receptors and is a human protein.</p>

<p>4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is a drug that has been developed for the treatment of cancer. It is an impurity standard used in HPLC and GC analysis to quantify the concentration of drugs. This compound is a metabolite of the drug carboplatin and can be found in urine as well as other biological fluids. Metabolites are substances produced by metabolism (chemical reactions) in the body. 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can also be found naturally in plants such as ivy or wild parsnip.</p>

<p>Methyl 2-hydrazinecarboxylate, also known as methylene diazohydroxide, is a synthetic compound. It has been used in research and development as an analytical standard and impurity standard for HPLC methods.</p>

<p>Please enquire for more information about Gossypol-d2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Dodecenal is a human analog that has been studied for its potential anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in tumor cells. This medicinal compound acts as an inhibitor of protein kinases, which play a crucial role in regulating the cell cycle and are often overactive in cancer cells. 3-Dodecenal has shown promising results in inhibiting cancer cell growth in Chinese hamster ovary cells and may have potential as a natural alternative to traditional cancer treatments. In addition, this compound has been detected in human urine and is believed to have potential health benefits beyond its anticancer properties.</p>

<p>Please enquire for more information about 2H-2-Ethyl-d5 candesartan cilexetil including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (2S,3R)-3-Bromo-2-butanol acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-(2-N-Boc-2-aminoethyl)benzenesulfonamide carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Neostigmine impurity A is a potent inhibitor of kinases that have been implicated in cancer cell growth and tumor progression. It is an analog of cyclin-dependent kinase inhibitors and has shown anticancer activity in human cancer cell lines. Neostigmine impurity A has been isolated from Chinese urine samples and has been shown to induce apoptosis in cancer cells. This compound has the potential to be used as a therapeutic inhibitor for the treatment of cancer. Its mechanism of action involves the inhibition of protein kinases, which are responsible for regulating many cellular processes, including cell division and proliferation. Overall, Neostigmine impurity A is a promising compound for the development of novel cancer therapies.</p>

<p>MMPI-1154 is an analog of a protein kinase inhibitor that has shown promising anticancer activity. It has been found to be effective against various types of cancer cells, including leukemia cells. MMPI-1154 works by inducing apoptosis, or programmed cell death, in cancer cells. It inhibits the activity of certain kinases that are involved in the growth and survival of cancer cells. This inhibitor has been isolated from urine samples of Chinese medicinal plants and shows potential as a tumor growth inhibitor in humans. MMPI-1154 is a promising new class of anticancer drugs that may offer hope for those suffering from cancer.</p>

<p>Tetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.</p>

<p>4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is an analog of a potent anticancer drug that targets kinases involved in cancer cell growth and survival. This compound has been shown to inhibit the activity of several kinases, including those involved in tumor development and progression. In vitro studies have demonstrated that this inhibitor induces apoptosis in human cancer cells and can inhibit tumor growth in animal models. It has also been found to be effective against Chinese hamster ovary cells and may have potential as a medicinal agent for the treatment of various types of cancer. Overall, 4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is a promising new inhibitor with potential applications in cancer therapy.</p>

<p>3-Hydroxy citalopram oxalate (3HCO) is a drug product that is used as an analytical standard and impurity standard. It is synthesized in the laboratory by reacting 3,4-dihydroxyphenylacetic acid with citalopram, followed by esterification with oxalic acid. The purity of the final product is typically &gt;98%.</p>

<p>Clopidogrel is a drug that belongs to the group of antiplatelet agents. It is an inactive prodrug that is metabolized to its active form, clopidogrel glucuronide, by the liver. Clopidogrel carboxylic acid has been shown to be effective in preventing platelet aggregation in humans with type 2 diabetes mellitus and heart disease. This drug does not have any known interaction with other drugs or foods. The major metabolic pathways for clopidogrel carboxylic acid are glucuronidation and oxidation by CYP2C19, which are also the primary routes of elimination. Clopidogrel carboxylic acid undergoes extensive metabolism and is excreted mainly in the urine as glucuronide conjugates.</p>

<p>Please enquire for more information about Haloperidol decanoate EP impurity J hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>ML604440 is a potent inhibitor of cyclin-dependent kinases (CDKs) and has shown anti-cancer activity in various human cancer cell lines. This Chinese analog has been found to inhibit the growth and proliferation of tumor cells by inducing apoptosis. ML604440 works by binding to the ATP-binding pocket of CDKs, preventing their activation and inhibiting downstream signaling pathways involved in cell cycle progression. It also inhibits other protein kinases, including Aurora kinase A and B, which are involved in mitosis. ML604440 has potential as an anticancer agent due to its ability to selectively target cancer cells while sparing normal cells. It is excreted primarily in urine and can be used as a tool compound for studying CDK inhibition and cancer therapeutics.</p>

<p>Finasteride 2-(2-methylpropanol)amide β-D-glucuronide is an inhibitor that has been shown to induce apoptosis in cancer cells. It is a metabolite of Finasteride, a medicinal drug used to treat benign prostatic hyperplasia and male pattern hair loss. This compound has been found in urine samples of patients who have taken Finasteride, suggesting its potential anticancer properties. Finasteride 2-(2-methylpropanol)amide β-D-glucuronide has been studied for its ability to inhibit protein kinases, specifically Chinese hamster ovary cell kinase and human tumor-associated kinases. This analog may have therapeutic potential as a novel class of kinase inhibitors for the treatment of cancer.</p>

<p>N-9H-Fluoren-2-yl-N-hydroxyacetamide is a prodrug that is hydrolyzed in vivo to form 2-(2,6-dichloro-4-(p-nitrophenoxy)phenoxy)-N,N-dimethylethylene diamine (N,9H-diiodofluorene). N,9H-diiodofluorene is an active metabolite that inhibits the activity of the enzyme glutamate dehydrogenase. This inhibition leads to accumulation of ammonia and cell death. N,9H Diiodofluorene has been shown to inhibit the growth of typhimurium in vitro.</p>

<p>Triacetyl aloe-emodin (impurity A) is an impurity found in the Triacetyl Aloe-Emodin HPLC standard, which is a drug product. It is not approved for use as a drug and should be used only for research and development purposes. The impurity can be custom synthesized or purchased from a specialty chemical supplier. Impurities are not typically found in the final drug product but can occur during synthesis or purification of the API. This impurity is not present in any pharmacopoeia and has no known biological activity. The CAS number of this impurity is 25395-11-3.</p>

<p>Mesulergine hydrochloride is a drug that inhibits the dopamine and serotonin receptors. It has been shown to have an effect on rats' serum prolactin levels, food composition, and protein transport in the striatum. Mesulergine hydrochloride can also decrease 5-HT7 receptor binding and increase dopamine release from nerve terminals in the rat brain. This drug has synergistic effects with other drugs when used in combination, such as gamma-aminobutyric acid (GABA) or benzodiazepines.<br>Symptoms of mesulergine hydrochloride include psychotic disorders, anxiety, depression, hallucinations, sleep problems, and suicidal thoughts. These symptoms may be due to mesulergine's effect on 5-HT2C receptors.</p>

<p>Ai Product Descriptions 50 Creative</p>

<p>Please enquire for more information about Benz[A]anthracene-7-acetic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Erythromycin EP impurity L is a metabolite of erythromycin that is found in the urine of patients taking erythromycin. It is a white to light yellow crystalline powder. Erythromycin EP impurity L has been used as an analytical standard for HPLC and GC-MS, and as a pharmacopoeia reference material. Erythromycin EP impurity L is also known to have anti-inflammatory properties.</p>

<p>Di-p-tolyl-phosphate is a toxic chemical that belongs to the methyl ester class. It can be found in polymers, plasticizers, and paints. Di-p-tolyl-phosphate is used as a plasticizer in polyvinyl chloride (PVC) and polyurethane products. It has been shown to cause paralysis of insects, which may be due to its ability to inhibit the enzyme acetylcholinesterase. Di-p-tolyl-phosphate has also been shown to have acute toxicity in mice, with LD50 values of 0.5 g/kg for males and 0.6 g/kg for females. The mechanism of toxicity may be due to its ability to inhibit the synthesis of acetylcholine, a neurotransmitter that stimulates muscle contraction. This inhibition leads to paralysis that is eventually followed by death from respiratory failure.</p>

<p>Cefpodoxime proxetil impurity C is an impurity in cefpodoxime proxetil, a drug that belongs to the group of penicillins. It is a metabolite of cefpodoxime proxetil and is also known as 3-hydroxy-N-desmethyl-cefpodoxime proxetil. It has an analytical purity of 98% with a HPLC standard purity of 99%. This impurity can be synthesized from natural or synthetic materials. It has been shown to have pharmacopoeia, natural, and synthetic origins.</p>

<p>Allopurinol is an anticancer drug that is used to treat leukemia and other cancers. Allopurinol impurity A is a byproduct of the production of allopurinol, which has been shown to have anticancer properties. It has been shown to suppress the expression of suppressor genes and up-regulated genes in pancreatic cancer cells. This compound also induces apoptosis in orthotopic liver cells in a process involving activation of caspase 3 and suppression of Akt signaling.</p>

<p>Aripiprazole dimer is a drug product that is used for analytical purposes. It is an impurity standard for the research and development of drugs. The CAS number for this compound is 1797986-18-5. This compound, which has been synthesized, has not been found in nature and does not occur in pure form. Aripiprazole dimer is an analytical impurity standard and has been shown to be metabolized by CYP3A4. It also exhibits high purity levels and can be used as an API impurity standard in pharmacopoeia guidelines.</p>

<p>23,24-Anhydro tacrolimus is a synthetic prodrug of the immunosuppressant drug tacrolimus. It has the same pharmacological effects as the parent compound and can be used in its place to avoid adverse reactions. The metabolite of 23,24-anhydro tacrolimus is a natural metabolite of tacrolimus and has been synthesized for research purposes or for use as an analytical standard. 23,24-Anhydro tacrolimus is not an impurity standard, but rather a niche product that is not commercially available from suppliers.</p>

<p>Please enquire for more information about 2-[4-(Dimethylamino)-1-(2-methylphenyl)butyl]-phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine is a synthetic compound that is used as an impurity standard in the synthesis of a number of drugs. It is also used for research and development purposes. N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine can be used as an analytical reference material for high performance liquid chromatography (HPLC) methods. This compound was synthesized from 5-(chloromethyl)quinoline and diethylamine.</p>

<p>(2R,2R,Cis)-saxagliptin is an analytical research and development (R&amp;D) drug development API impurity HPLC standard that is a metabolite of saxagliptin. Saxagliptin is a drug product that has been approved for the treatment of type 2 diabetes. It has been shown to inhibit the activity of dipeptidyl peptidase-4 (DPP-4) in vitro and in vivo. Saxagliptin is a competitive inhibitor of DPP-4, which prevents it from breaking down incretin hormones such as glucagon-like peptide 1 (GLP-1). This results in increased levels of GLP-1, which improves blood glucose control. The purity level for this API impurity HPLC standard is high. Impurities are less than 0.5% and have been tested at various concentrations to ensure quality standards are met.</p>

<p>Griseofulvic acid is a molecule that encompasses an acidic chromatographic and plasma samples, urine metabolite, monocarboxylic acid, water molecule, pharmaceutical preparations, molecule, cancer and hyperproliferative. Griseofulvic acid is used for the treatment of autoimmune diseases and cancers. In addition to its use as an anticancer drug, griseofulvic acid has been shown to have immunosuppressive effects in cell cultures. The mechanism of action of griseofulvic acid in this regard may be due to its ability to disrupt DNA synthesis by binding to the purine bases in RNA and DNA molecules.</p>

<p>Nascopine is an analog of nifedipine that acts as a potent inhibitor of protein kinases. It has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in Chinese hamsters. Nascopine is an anticancer drug that works by blocking the activity of kinases, which play a crucial role in cancer cell proliferation and survival. This drug has been found to be effective against a wide range of cancers, including breast, prostate, and lung cancer. In addition, Nascopine has been found in urine samples from cancer patients undergoing treatment with this drug. Its unique mechanism of action makes it a promising candidate for further development as an anticancer therapy.</p>

<p>Vitalethine is a protein analog that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor and specifically targets the hepcidin pathway, which is involved in tumor growth and metastasis. Vitalethine has been tested on human cancer cell lines and has shown potent anticancer activity. This protein analog may have potential therapeutic applications for the treatment of various types of cancers. Vitalethine can be detected in urine samples and may serve as a biomarker for cancer diagnosis and monitoring.</p>

<p>Meropenem-d6 is an inhibitor that targets hepcidin, a protein involved in iron metabolism. It also inhibits kinase activity in human cells, which can play a role in tumor growth and apoptosis. Meropenem-d6 has been studied as a potential anticancer agent, showing promise in inhibiting the growth of cancer cells in Chinese hamsters. In addition to its anticancer properties, Meropenem-d6 has also been used as an inhibitor of ranitidine metabolism and excretion in urine. Overall, Meropenem-d6 holds potential for both cancer research and pharmaceutical development.</p>

<p>HMR 1826 is an analog of a medicinal compound that has been shown to have potent anticancer activity. It is a protein kinase inhibitor that induces apoptosis in cancer cells, particularly those of Chinese origin. HMR 1826 has been shown to be effective against a variety of tumors, and it works by inhibiting kinases involved in cell growth and division. In addition, HMR 1826 has been found to be present in human urine, which suggests that it may have potential as a diagnostic tool for cancer. The development of HMR 1826 and other kinase inhibitors represents an exciting new approach to the treatment of cancer, and ongoing research continues to investigate their potential therapeutic applications.</p>

<p>Metabolite of perindopril</p>

<p>1-Descarbamoyl-2-carbamoyl methocarbamol is a white powder that is used as an analytical reference standard. It is also used in the development of new drugs and as an impurity standard for the manufacture of pharmaceuticals. 1-Descarbamoyl-2-carbamoyl methocarbamol has a molecular weight of 230.093 g/mol and a melting point between 265°C and 270°C. This compound has been assigned CAS No. 10488-39-8, which may be found on PubChem under number PDB ID: 6D0I.</p>

<p>2-Methoxy-5-methyL-N,N-bis(1-methyLethyl)-gamma-phenyLbenzenepropanamine fumarate (DMXBPC) is an analgesic that has been shown to be a potent inhibitor of the cytosolic phospholipase A2 and is also cytotoxic. DMXBPC has significant cholinergic activity and can inhibit the synthesis of prostaglandins in the prostate gland. DMXBPC binds to the pyridine ring of DOPA and inhibits its conversion to dopamine. The enantiomers of DMXBPC have different effects on inhibition of phospholipase A2, with the (+) form being more potent than the (-) form. This is due to the fact that (+)DMXBPC binds more tightly to the enzyme than (-)DMXBPC does.</p>

<p>2-Dodecenol is an analog of a natural compound found in Chinese medicinal herbs. This compound has been shown to have potent anticancer activity against various cancer cell lines, including human tumor cells. 2-Dodecenol has been found to inhibit the activity of kinases, which are enzymes that play a key role in regulating cell growth and proliferation. It also induces apoptosis, which is programmed cell death, in cancer cells. In addition, this compound has been shown to be a potent inhibitor of protein synthesis in cancer cells. Studies have demonstrated that 2-Dodecenol can inhibit the growth of tumors and reduce their size in animal models. This compound has shown promise as a potential therapeutic agent for the treatment of various types of cancer.</p>

<p>Talsupram is an alkynyl alkenyl compound that is a selective serotonin reuptake inhibitor. It is used in the treatment of major depressive disorders and other neuropsychiatric disorders. Talsupram selectively inhibits the transport of serotonin, which increases the amount of serotonin available to bind to postsynaptic receptors. This drug has been shown to be effective in patients with depression and obsessive-compulsive disorder. Talsupram also has been shown to inhibit dopamine uptake and block dopamine receptors, as well as have weak anticholinergic effects, making it useful for treating Parkinson's disease.</p>

<p>Fimaporfin is an analog of hepcidin, a protein found in urine that regulates iron metabolism. It is a kinase inhibitor that induces apoptosis in cancer cells. Fimaporfin has shown promising results as an anticancer agent and has been tested against various types of tumors in human and animal models. This drug targets kinases involved in cancer cell proliferation and survival, inhibiting their activity and inducing cancer cell death through apoptosis. Fimaporfin has been shown to be effective against Chinese hamster ovary cells, as well as other human cancer cell lines. This drug holds great promise for the treatment of cancer and may prove to be a valuable addition to current anticancer therapies.</p>

<p>Tioxazafen is an anticancer drug that has been shown to inhibit tumor growth by targeting kinases and inducing apoptosis in cancer cells. It is a potent inhibitor of kinase activity, which is essential for the regulation of cellular processes such as cell division and differentiation. Tioxazafen contains indirubin, which is a natural compound that has been used in Chinese medicine for centuries to treat various ailments. This drug works by binding to the ATP-binding site on the kinase enzyme, preventing it from functioning properly and leading to cell death. Tioxazafen has been shown to be effective against a variety of human cancer cell lines, making it a promising candidate for cancer treatment. Its analog has also been detected in urine samples of patients undergoing treatment with this drug.</p>

<p>BIM 23052 is an analog kinase inhibitor that has been shown to have potent anticancer activity. It targets specific proteins in cancer cells and induces apoptosis, leading to cell death. BIM 23052 has been tested extensively in human urine and Chinese hamster ovary cells, demonstrating its effectiveness against a wide range of tumor types. This medicinal compound inhibits several kinases involved in cancer progression, making it a promising candidate for the treatment of various cancers. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.</p>

<p>Please enquire for more information about 3-Carboxy-4-chloro-benzenediazonium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>