Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(167 produits)
- Bcr-Abl(118 produits)
- EGFR(581 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2382 produits trouvés pour "Angiogenèse"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
MAZ51
CAS :MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formule :C21H18N2ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :314.38Semaxinib
CAS :Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.
Formule :C15H14N2ODegré de pureté :99.84%Couleur et forme :Yellow To Yellow OrangeMasse moléculaire :238.28JANEX-1
CAS :JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formule :C16H15N3O3Degré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :297.31SAR-20347
CAS :SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).Formule :C21H18ClFN4O4Degré de pureté :98.99% - 99.77%Couleur et forme :SolidMasse moléculaire :444.84Ref: TM-T4210
1mg34,00€5mg75,00€10mg110,00€25mg215,00€50mg334,00€100mg557,00€200mg775,00€1mL*10mM (DMSO)84,00€WZ8040
CAS :WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).Formule :C24H25ClN6OSDegré de pureté :97.42% - 99.785%Couleur et forme :SolidMasse moléculaire :481.01Tyrphostin 23
CAS :Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.Formule :C10H6N2O2Degré de pureté :99.7% - 99.86%Couleur et forme :Yellow-Tan SolidMasse moléculaire :186.17(Z)-Semaxinib
CAS :(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition forFormule :C15H14N2ODegré de pureté :98.82% - ≥95%Couleur et forme :SolidMasse moléculaire :238.28Ref: TM-T2496
10mg35,00€25mg52,00€50mg79,00€100mg111,00€200mg168,00€500mg330,00€1mL*10mM (DMSO)44,00€Epidermal Growth Factor
CAS :EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Formule :C270H401N73O83S7Degré de pureté :97.17%Couleur et forme :SolidMasse moléculaire :6222Verteporfin
CAS :Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formule :C41H42N4O8Degré de pureté :95.37% - 99.82%Couleur et forme :Dark Green To Black SolidMasse moléculaire :718.79Ref: TM-T3112
1mg38,00€2mg49,00€5mg80,00€10mg109,00€25mg213,00€50mg346,00€100mg437,00€1mL*10mM (DMSO)114,00€Afatinib
CAS :Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formule :C24H25ClFN5O3Degré de pureté :98.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94Ref: TM-T21312
5mg34,00€10mg49,00€25mg81,00€50mg109,00€100mg137,00€200mg168,00€500mg284,00€1mL*10mM (DMSO)50,00€MGCD-265 analog
CAS :Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formule :C26H20FN5O2S2Degré de pureté :98.06% - 98.68%Couleur et forme :SolidMasse moléculaire :517.6SSR128129E
CAS :SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.Formule :C18H15N2O4·NaDegré de pureté :98.79% - ≥95%Couleur et forme :SolidMasse moléculaire :346.31BMS 599626 2HCl
CAS :BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100Formule :C27H29FN8O3Cl2Degré de pureté :99.94%Couleur et forme :SoildMasse moléculaire :603.48ZM39923 hydrochloride
CAS :ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formule :C23H25NO·HClDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :367.91Vactosertib Hydrochloride
CAS :Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an ALK5 inhibitor, a TGF-β receptor I inhibitor with antimetastatic and anticancer effects.Formule :C22H19ClFN7Degré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :435.89Ref: TM-T15262
1mg34,00€5mg66,00€10mg92,00€25mg152,00€50mg230,00€100mg356,00€200mg522,00€1mL*10mM (DMSO)73,00€VX-11e
CAS :VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formule :C24H20Cl2FN5O2Degré de pureté :98.92% - ≥98%Couleur et forme :SolidMasse moléculaire :500.35Cerdulatinib
CAS :Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formule :C20H27N7O3SDegré de pureté :98.74% - 99.49%Couleur et forme :SolidMasse moléculaire :445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€1mL*10mM (DMSO)81,00€Fursultiamine
CAS :Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.Formule :C17H26N4O3S2Degré de pureté :99.63% - 99.90%Couleur et forme :SolidMasse moléculaire :398.54PF-431396
CAS :PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).Formule :C22H21F3N6O3SDegré de pureté :98.83% - 99.82%Couleur et forme :SolidMasse moléculaire :506.5BMS-536924
CAS :BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96RN486
CAS :RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).Formule :C35H35FN6O3Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :606.69KW-2449
CAS :KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formule :C20H20N4ODegré de pureté :98.43% - 99.69%Couleur et forme :SolidMasse moléculaire :332.4JAK3-IN-6
CAS :JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nMFormule :C19H18N4O3Degré de pureté :99.94% - 99.94%Couleur et forme :SolidMasse moléculaire :350.37SU 4313
CAS :SU 4313 is a bioactive chemical.Formule :C18H17NODegré de pureté :99.51% - 99.89%Couleur et forme :SolidMasse moléculaire :263.33Ref: TM-T3568
1mg34,00€5mg66,00€10mg92,00€25mg167,00€50mg236,00€100mg353,00€200mg517,00€1mL*10mM (DMSO)73,00€WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.Formule :C16H14Br2ClN3O3Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :491.56Ref: TM-T4657L
2mg34,00€5mg48,00€10mg86,00€25mg138,00€50mg182,00€100mg261,00€200mg371,00€1mL*10mM (DMSO)73,00€PD173074
CAS :PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formule :C28H41N7O3Degré de pureté :98.15% - 98.21%Couleur et forme :Yellow SolidMasse moléculaire :523.67Ref: TM-T2642
5mg40,00€10mg54,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€1mL*10mM (DMSO)56,00€Ningetinib
CAS :Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formule :C31H29FN4O5Degré de pureté :99.95% - 99.98%Couleur et forme :SolidMasse moléculaire :556.58PF-562271 hydrochloride
CAS :PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.Formule :C21H20F3N7O3SHClDegré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :543.95WDR5-0103 hydrochloride[890190-22-4(free base)]
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd:Formule :C21H26ClN3O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :419.9Multi-kinase inhibitor 1
CAS :Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formule :C20H17F3N4O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :418.37Ref: TM-T4191
1mg37,00€2mg52,00€5mg79,00€10mg101,00€25mg177,00€50mg268,00€100mg385,00€1mL*10mM (DMSO)87,00€A-419259
CAS :A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.Formule :C29H34N6ODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :482.62Fruquintinib
CAS :Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-Formule :C21H19N3O5Degré de pureté :98.84% - 99.89%Couleur et forme :SolidMasse moléculaire :393.39Ref: TM-T2656
2mg35,00€5mg52,00€10mg85,00€25mg117,00€50mg147,00€100mg250,00€500mg620,00€1mL*10mM (DMSO)58,00€Epitinib
CAS :Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).Formule :C24H26N6O2Couleur et forme :SolidMasse moléculaire :430.5BFH772
CAS :BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formule :C23H16F3N3O3Degré de pureté :97.71% - 99.89%Couleur et forme :SolidMasse moléculaire :439.39SKLB4771
CAS :SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Formule :C25H27N7O3S2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :537.66Ref: TM-T2051
1mg63,00€2mg93,00€5mg124,00€10mg177,00€25mg371,00€50mg557,00€100mg792,00€500mg1.611,00€1mL*10mM (DMSO)148,00€(Z)-LFM-A13
CAS :(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formule :C11H8Br2N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :360Zorifertinib
CAS :Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formule :C22H23ClFN5O3Degré de pureté :98.20% - 99.36%Couleur et forme :White To Off-White SolidMasse moléculaire :459.9SU14813
CAS :SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formule :C23H27FN4O4Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :442.48NVP-BSK805 trihydrochloride
CAS :NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.Formule :C27H31Cl3F2N6OCouleur et forme :SolidMasse moléculaire :599.932,4-DPD
CAS :2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)Formule :C11H13NO4Degré de pureté :99.74%Couleur et forme :Yellow Solid CrystallineMasse moléculaire :223.23Delgocitinib EtOH
CAS :Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formule :C18H24N6O2Couleur et forme :SolidMasse moléculaire :356.43PCI 29732
CAS :PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.Formule :C22H21N5ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :371.432-(1,8-naphthyridin-2-yl)phenol
CAS :2-NP is a STAT1 enhancer.Formule :C14H10N2ODegré de pureté :99.33% - 99.82%Couleur et forme :SolidMasse moléculaire :222.24Ref: TM-T2168
5mg57,00€10mg90,00€25mg177,00€50mg281,00€100mg444,00€200mg647,00€500mg982,00€1mL*10mM (DMSO)63,00€Tropisetron
CAS :Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.Formule :C17H20N2O2Degré de pureté :99.68%Couleur et forme :White SolidMasse moléculaire :284.35GDC-0214
CAS :GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formule :C28H28ClF2N9O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :612.03Ref: TM-T9826
1mg93,00€5mg182,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)245,00€SB-431542
CAS :SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.Formule :C22H16N4O3Degré de pureté :99.035% - >99.99%Couleur et forme :SolidMasse moléculaire :384.39SU4312
CAS :SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.Formule :C17H16N2ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :264.32SCR-1481B1
CAS :SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormule :C32H40ClF2N6O13PDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :821.12Ref: TM-T5349
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg200,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)102,00€Radotinib
CAS :Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably
Formule :C27H21F3N8ODegré de pureté :99.13% - 99.97%Couleur et forme :SolidMasse moléculaire :530.5Protein kinase inhibitor 6
CAS :Protein kinase inhibitor 6 is a protein kinase inhibitor.Formule :C13H9FN2SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T9779
2mg34,00€5mg52,00€10mg86,00€25mg163,00€50mg222,00€100mg324,00€200mg440,00€1mL*10mM (DMSO)52,00€Avitinib maleate
CAS :Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.Formule :C30H30FN7O6Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :603.617BIO
CAS :7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formule :C16H10BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :356.17Nastorazepide
CAS :Nastorazepide is a selective, orally available antagonist of gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.Formule :C29H36N4O5Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :520.62Quizartinib HCl
CAS :Quizartinib (AC220/AC010220) is an oral FLT3/STK1 inhibitor for treating AML, blocking kinase-driven cell proliferation and promoting apoptosis.Formule :C29H34Cl2N6O4SCouleur et forme :SolidMasse moléculaire :633.59SGI-7079
CAS :SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.Formule :C26H26FN7Degré de pureté :95.51% - 99.26%Couleur et forme :SolidMasse moléculaire :455.53Ref: TM-T6982
2mg39,00€5mg58,00€10mg92,00€25mg178,00€50mg230,00€100mg334,00€500mg782,00€1mL*10mM (DMSO)64,00€FGFR4-IN-1
CAS :FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).Formule :C24H27N7O5Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :493.52Amuvatinib
CAS :Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Formule :C23H21N5O3SDegré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :447.51AZ7550
CAS :AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formule :C27H31N7O2Degré de pureté :97.07% - 99.75%Couleur et forme :SolidMasse moléculaire :485.58PRT-060318
CAS :PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formule :C18H24N6ODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :340.42PP 3
CAS :PP 3 is a Negative control for the Src kinase inhibitor PP 2Formule :C11H9N5Degré de pureté :98.61%Couleur et forme :Whit To Off-White SolidMasse moléculaire :211.22Oclacitinib
CAS :Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000Formule :C15H23N5O2SDegré de pureté :98% - 98.45%Couleur et forme :White To Off-White SolidMasse moléculaire :337.44WHI-P180
CAS :WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formule :C16H15N3O3Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :297.31CCT241736
CAS :CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formule :C22H23Cl2N7Degré de pureté :96.2% - 99.81%Couleur et forme :SolidMasse moléculaire :456.37Peficitinib
CAS :Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formule :C18H22N4O2Degré de pureté :98.67% - 99.4%Couleur et forme :SolidMasse moléculaire :326.39Ref: TM-T6933
2mg38,00€5mg63,00€10mg99,00€25mg172,00€50mg268,00€100mg416,00€200mg610,00€1mL*10mM (DMSO)70,00€PD-089828
CAS :PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Formule :C18H18Cl2N6ODegré de pureté :97.39%Couleur et forme :SolidMasse moléculaire :405.28FLT3-IN-2
CAS :FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).Formule :C21H16ClF3N4Degré de pureté :97.57% - 98.53%Couleur et forme :SolidMasse moléculaire :416.83Ref: TM-T1938
1mg40,00€2mg52,00€5mg82,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€1mL*10mM (DMSO)93,00€Gefitinib dihydrochloride
CAS :Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.Formule :C22H26Cl3FN4O3Couleur et forme :SolidMasse moléculaire :519.821-Naphthyl PP1
CAS :1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Formule :C19H19N5Degré de pureté :99.85%Couleur et forme :White Cyrstalline SolidMasse moléculaire :317.39SYR127063
CAS :SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.Formule :C23H20ClF3N4O3Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :492.88S49076
CAS :S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.Formule :C22H22N4O4SDegré de pureté :95.35% - 97.4%Couleur et forme :SolidMasse moléculaire :438.5Ref: TM-T3274
1mg34,00€2mg44,00€5mg58,00€10mg93,00€25mg167,00€50mg260,00€100mg432,00€200mg618,00€1mL*10mM (DMSO)64,00€AMG 925 HCl
CAS :AMG 925 HCl is a selective and potent dual inhibitor of FLT3 (IC50: 2±1 nM) and CDK4 (IC50: 3±1 nM).Formule :C26H30ClN7O2Couleur et forme :SolidMasse moléculaire :508.02BAY 61-3606 HCl
CAS :BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Formule :C20H19ClN6O3Couleur et forme :SolidMasse moléculaire :426.86Desmethyl Erlotinib hydrochloride
CAS :Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor.Formule :C21H21N3O4·HClDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :415.87Ref: TM-T6619
1mg56,00€2mg79,00€5mg109,00€10mg178,00€25mg318,00€50mg479,00€100mg682,00€1mL*10mM (DMSO)120,00€Ruxolitinib (S enantiomer)
CAS :Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formule :C17H18N6Degré de pureté :99.37% - 99.79%Couleur et forme :SolidMasse moléculaire :306.36GluR6 antagonist-1
CAS :GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.Formule :C15H11ClN2OSDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :302.78Syk Inhibitor II dihydrochloride
CAS :Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formule :C14H17Cl2F3N6ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :413.22Ref: TM-T4391
1mg130,00€2mg212,00€5mg455,00€10mg647,00€25mg947,00€50mg1.264,00€100mg1.700,00€1mL*10mM (DMSO)455,00€WHI-P97
CAS :WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formule :C16H13Br2N3O3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :455.1Belzutifan
CAS :"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formule :C17H12F3NO4SDegré de pureté :99.34% - 99.88%Couleur et forme :SolidMasse moléculaire :383.34Ref: TM-T16679
1mg66,00€5mg144,00€10mg205,00€25mg389,00€50mg625,00€100mg888,00€200mg1.198,00€1mL*10mM (DMSO)158,00€5'-Fluoroindirubinoxime
CAS :5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).Formule :C16H10FN3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :295.27Merestinib dihydrochloride
CAS :Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.Formule :C30H24Cl2F2N6O3Couleur et forme :SolidMasse moléculaire :625.45KC7F2
CAS :KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formule :C16H16Cl4N2O4S4Degré de pureté :98% - 99.11%Couleur et forme :SolidMasse moléculaire :570.38Arnebin 1
CAS :(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.Formule :C21H22O6Degré de pureté :98.76% - 99.81%Couleur et forme :SolidMasse moléculaire :370.40Ref: TM-T4586
1mg34,00€5mg67,00€10mg96,00€25mg138,00€50mg200,00€100mg294,00€200mg437,00€1mL*10mM (DMSO)74,00€SU4984
CAS :SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).Formule :C20H19N3O2Degré de pureté :97.20%Couleur et forme :SolidMasse moléculaire :333.38GLPG0634 analog
CAS :GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formule :C23H18N6O2Degré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :410.43Ref: TM-T3076
1mg38,00€2mg50,00€5mg84,00€10mg137,00€25mg250,00€50mg442,00€100mg623,00€500mg1.305,00€1mL*10mM (DMSO)93,00€GSK1838705A
CAS :GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formule :C27H29FN8O3Degré de pureté :98.89% - >99.99%Couleur et forme :SolidMasse moléculaire :532.57CZC-8004
CAS :CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34ZM 306416
CAS :ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).Formule :C16H13ClFN3O2Degré de pureté :99.37% - ≥95%Couleur et forme :SolidMasse moléculaire :333.74Tyrphostin AG 879
CAS :Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.Formule :C18H24N2OSDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :316.46Spebrutinib
CAS :Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplasticFormule :C22H22FN5O3Degré de pureté :97.02% - >99.99%Couleur et forme :SolidMasse moléculaire :423.44RAF265
CAS :RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formule :C24H16F6N6ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :518.41Ref: TM-T6296
1mg44,00€2mg59,00€5mg93,00€10mg140,00€25mg253,00€50mg413,00€100mg605,00€1mL*10mM (DMSO)94,00€TL-895
CAS :TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).Formule :C25H26FN5O2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :447.5Ref: TM-T9705
2mg39,00€5mg60,00€10mg87,00€25mg172,00€50mg266,00€100mg391,00€200mg555,00€1mL*10mM (DMSO)60,00€E-4031 dihydrochloride
CAS :E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formule :C21H29Cl2N3O3SDegré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :474.44TAK-593
CAS :TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formule :C23H23N7O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :445.47Ref: TM-T16975
2mg42,00€5mg62,00€10mg96,00€25mg182,00€50mg284,00€100mg409,00€200mg575,00€1mL*10mM (DMSO)73,00€Cabozantinib S-malate
CAS :Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.Formule :C32H30FN3O10Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :635.59UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formule :C19H25ClN8Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :400.91Ref: TM-T2056L
1mg84,00€5mg168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€1mL*10mM (DMSO)185,00€Cabozantinib hydrochloride
CAS :Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formule :C28H25ClFN3O5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :537.96Ref: TM-T5164
1mg42,00€2mg52,00€5mg65,00€10mg92,00€25mg160,00€50mg235,00€100mg330,00€200mg538,00€500mg860,00€Nocodazole
CAS :Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32Ref: TM-T2802
5mg34,00€10mg52,00€25mg94,00€50mg165,00€100mg268,00€200mg399,00€500mg647,00€1mL*10mM (DMSO)38,00€Vandetanib trifluoroacetate
CAS :Vandetanib trifluoroacetate: oral VEGFR2/KDR inhibitor, IC50=40nM, also blocks VEGFR3/FLT4 (110nM) and EGFR/HER1 (500nM).Formule :C24H25BrF4N4O4Couleur et forme :SolidMasse moléculaire :589.386CP-380736
CAS :CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formule :C14H18N2O5Degré de pureté :99.68%Couleur et forme :White To Off-White SolidMasse moléculaire :294.3Toceranib Phosphate
CAS :Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formule :C22H28FN4O6PDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :494.45
![WDR5-0103 hydrochloride[890190-22-4(free base)]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5140.webp&w=3840&q=75)
