Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2235 produits trouvés pour "Chromatine/Épigénétique"
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(Z)-SMI-4a
CAS :<p>(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.</p>Formule :C11H6F3NO2SDegré de pureté :97.66% - 99.93%Couleur et forme :SolidMasse moléculaire :273.23Oclacitinib
CAS :<p>Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000</p>Formule :C15H23N5O2SDegré de pureté :98% - 98.45%Couleur et forme :White To Off-White SolidMasse moléculaire :337.44lutidinic acid
CAS :<p>lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.</p>Formule :C7H5NO4Degré de pureté :98.06%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :167.12RG108
CAS :<p>RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).</p>Formule :C19H14N2O4Degré de pureté :98% - 99.43%Couleur et forme :SolidMasse moléculaire :334.33SGC-CBP30
CAS :<p>SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).</p>Formule :C28H33ClN4O3Degré de pureté :99.05% - >99.99%Couleur et forme :SolidMasse moléculaire :509.04AZD-1480
CAS :<p>AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.</p>Formule :C14H14ClFN8Degré de pureté :98.25% - 99.47%Couleur et forme :SolidMasse moléculaire :348.77JAK-IN-5 hydrochloride
CAS :<p>JAK-IN-5 hydrochloride is a JAK inhibitor [1].</p>Formule :C27H32ClFN6OCouleur et forme :SolidMasse moléculaire :511.03Barasertib-HQPA
CAS :<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56ARV-825
CAS :<p>ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.</p>Formule :C46H47ClN8O9SDegré de pureté :97.15% - 98%Couleur et forme :SolidMasse moléculaire :923.43UNC6934
CAS :<p>UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.</p>Formule :C24H21N5O4Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :443.45Annaosanchun
CAS :<p>Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).</p>Formule :C19H32O3Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :308.46GS-829845
CAS :<p>GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life</p>Formule :C17H19N5O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :357.43CX-6258 hydrochloride
CAS :<p>CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).</p>Formule :C26H24ClN3O3·HClDegré de pureté :96.03% - 98.60%Couleur et forme :SolidMasse moléculaire :498.4CBHcy
CAS :<p>CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.</p>Formule :C9H17NO4SDegré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :235.3TNG-462
CAS :<p>TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).</p>Formule :C28H36N6O2SDegré de pureté :98.7%Couleur et forme :SolidMasse moléculaire :520.69MIV-6R
CAS :<p>MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.</p>Formule :C27H35N3ODegré de pureté :99.81% - 99.88%Couleur et forme :SolidMasse moléculaire :417.59Talazoparib tosylate
CAS :<p>PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.</p>Formule :C26H22F2N6O4SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :552.55Zavondemstat
CAS :<p>Zavondemstat (QC8222 free base) is a KDM4 inhibitor with anticancer and antitumor activity for the study of triple-negative and breast cancers.</p>Formule :C26H29N3O3Degré de pureté :99.43% - 99.53%Couleur et forme :SolidMasse moléculaire :431.53MS023 dihydrochloride
CAS :<p>MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.</p>Formule :C17H27Cl2N3ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :360.32Cerdulatinib hydrochloride
CAS :<p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.</p>Formule :C20H28ClN7O3SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :482Chromium(III) acetate
CAS :<p>Chromium(III) acetate （Chromium acetate） is a small molecule ionic crosslinker that is used as a feedstock for the synthesis of other compounds.</p>Formule :C2H3O2CrDegré de pureté :99.9%Couleur et forme :Blue-Green Powder Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Is Used InMasse moléculaire :76.37(S)-HH2853
CAS :<p>(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune research.</p>Formule :C31H36F3N7O3Degré de pureté :97.18% - 99.74%Couleur et forme :SolidMasse moléculaire :611.66MRK-740
CAS :<p>MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.</p>Formule :C25H32N6O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :464.56BI-9321 trihydrochloride
CAS :<p>BI-9321 trihydrochloride (BI9321 trihydrochloride) is an NSD3-PWWP1 antagonist that downregulates Myc messenger RNA expression.</p>Formule :C22H24Cl3FN4Degré de pureté :99.12% - 99.34%Couleur et forme :SolidMasse moléculaire :469.81R 59-022
CAS :<p>R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.</p>Formule :C27H26FN3OSDegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :459.58PFI-2
CAS :<p>PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other</p>Formule :C23H25F4N3O3SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :499.52NVP-BSK805
CAS :<p>NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.</p>Formule :C27H28F2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.55MK-5108
CAS :<p>MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.</p>Formule :C22H21ClFN3O3SDegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :461.94Dehydrocorydaline nitrate
CAS :<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formule :C22H24N2O7Degré de pureté :99.79% - 99.92%Couleur et forme :SolidMasse moléculaire :428.44SCH-1473759 hydrochloride
CAS :<p>SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).</p>Formule :C20H27ClN8OSDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :463GSK2807 Trifluoroacetate
CAS :<p>GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).</p>Formule :C21H33F3N8O7Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :566.53(R)-Dihydrolipoic acid
CAS :<p>(R)-Dihydrolipoic acid, the biochemically significant R-enantiomer, partakes in biochemical transformations.</p>Formule :C8H16O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :208.33Solrikitug
CAS :<p>Solrikitug,Anti-CRLF2 humanized IgG1κ monoclonal antibody.</p>Degré de pureté :95%Couleur et forme :LiquidTazemetostat trihydrochloride
CAS :<p>Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.</p>Formule :C34H47Cl3N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :682.12Acedapsone
CAS :<p>Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.</p>Formule :C16H16N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.37Diethyl bipy55'DC
CAS :<p>"Diethyl bipy55'DC blocks CP4H, crucial for collagen stability via hydroxylation in cells."</p>Formule :C16H16N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.312-PADQZ
CAS :<p>DPQ is an antiviral compound.</p>Formule :C14H19N5O2Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :289.33Nicotinamide-d4
CAS :<p>Nicotinamide-d4 is a deuterium-labelled compound of nicotinamide for isotope tracing. Nicotinamide, a vitamin B3 derivative, inhibits SIRT1 and SIRT2.</p>Formule :C6H2D4N2ODegré de pureté :99.746%Couleur et forme :SolidMasse moléculaire :126.15193 D7
CAS :<p>193 D7 is an inhibitor of histone demethylase JMJD1C (IC50= 0.59 μM in in vitro demethylation assay). In vivo, 193 D7 suppresses tumors by targeting intratumoral Treg cells in mouse tumor models.</p>Formule :C16H15NO4SCouleur et forme :SolidMasse moléculaire :317.36GSK 4027
CAS :<p>GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.</p>Formule :C17H21BrN4OCouleur et forme :SolidMasse moléculaire :377.28I-BET787
CAS :<p>I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.</p>Formule :C16H20ClN3O2Couleur et forme :SolidMasse moléculaire :321.80CrBKA
CAS :<p>CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .</p>Formule :C28H31N3O6Couleur et forme :SolidMasse moléculaire :505.56AdipoR agonist 1
CAS :<p>AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.</p>Formule :C26H35N3O3Couleur et forme :SolidMasse moléculaire :437.57HDAC6-IN-27
CAS :<p>HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].</p>Formule :C15H15N3O4Couleur et forme :SolidMasse moléculaire :301.3BG47
CAS :<p>BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.</p>Formule :C25H22N4O2SCouleur et forme :SolidMasse moléculaire :442.54Guanosine-5'-triphosphate disodium salt
CAS :<p>5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.</p>Formule :C10H14N5Na2O14P3Degré de pureté :95.69% - 99.96%Couleur et forme :Odorless White SolidMasse moléculaire :567.14GSK-J1 lithium salt
CAS :<p>GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.</p>Formule :C22H22LiN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.38BG14
CAS :<p>BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.</p>Formule :C21H21N5OCouleur et forme :SolidMasse moléculaire :359.433KAT6-IN-1
CAS :<p>KAT6-IN-1 is a potent KAT6 inhibitor. KAT6-IN-1 can be used in research of cancer [1] .</p>Formule :C19H18N4O5SCouleur et forme :SolidMasse moléculaire :414.43ZM39923
CAS :<p>ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).</p>Formule :C23H25NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.45KR-39038
CAS :<p>KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.</p>Formule :C24H32ClFN6OCouleur et forme :SolidMasse moléculaire :475.00BChE/HDAC6-IN-2
CAS :<p>BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.</p>Formule :C27H30N4O4Degré de pureté :98.47%Couleur et forme :SoildMasse moléculaire :474.55BG48
CAS :<p>BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.</p>Formule :C25H23N5OSCouleur et forme :SolidMasse moléculaire :441.55(3S,4S)-Tofacitinib
CAS :<p>(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.</p>Formule :C16H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.37Asteltoxin
CAS :<p>Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.</p>Formule :C23H30O7Couleur et forme :SolidMasse moléculaire :418.486HDAC2-IN-2
CAS :<p>HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.</p>Formule :C18H15N3O3SCouleur et forme :SolidMasse moléculaire :353.40E3330
CAS :<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formule :C21H30O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :378.46TMPA
CAS :<p>TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.</p>Formule :C21H32O6Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :380.48GSK-1268997
CAS :<p>GSK-1268997 is a bio-active chemical.</p>Formule :C21H23N7O3SDegré de pureté :99.33% - 99.81%Couleur et forme :SolidMasse moléculaire :453.52UNC0224
CAS :<p>UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.</p>Formule :C26H43N7O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :485.67MY-1B
CAS :<p>MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.</p>Formule :C22H18BrN3O2Degré de pureté :99.81% - >99.99%Couleur et forme :SoildMasse moléculaire :436.3JAK-IN-30
CAS :<p>JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50</p>Formule :C19H26N8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.53ZYJ-34c
CAS :<p>ZYJ-34c is a potent oral antitumor activities histone deacetylase inhibitor (HDACi).</p>Formule :C31H42N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :582.69SIRT1-IN-3
CAS :<p>SIRT1-IN-3 (compound 3j) is a potent and selective inhibitor of silent information regulator 1 (SIRT1) with an IC 50 of 4.2 μM [1].</p>Formule :C13H15BrN2OCouleur et forme :SolidMasse moléculaire :295.17Eleven-Nineteen-Leukemia Protein IN-1
CAS :<p>ENL-IN-1: Potent ENL YEATS domain inhibitor with 14.5 nM IC50, enhances thermal stability in vitro.</p>Formule :C27H33N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.6Angiogenesis agent 1
CAS :<p>Compound C-31, a salidroside-based glycoside, activates HIF-1α and may aid in diabetic limb ischemia studies.</p>Formule :C20H24O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.4LSD1-IN-5
CAS :<p>LSD1-IN-5, a reversible LSD1 inhibitor, boosts H3K4me2 without affecting LSD1 expression; IC50: 121 nM.</p>Formule :C15H13BrN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.18EZH2-IN-7
CAS :<p>EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.</p>Formule :C31H37D2N5O3SCouleur et forme :SolidMasse moléculaire :563.75CM-579
CAS :<p>CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.</p>Formule :C29H40N4O3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :492.655-Aza-4'-thio-2'-deoxycytidine
CAS :<p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>Formule :C8H12N4O3SCouleur et forme :SolidMasse moléculaire :244.27Tripolin A
CAS :<p>Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)</p>Formule :C15H11NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :253.25DC_C66
CAS :<p>DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.</p>Formule :C28H22NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :404.48Aurora kinase inhibitor-9
CAS :<p>Aurora kinase inhibitor-9 (9d) targets AURKA/B with IC50: 0.093 μM for A and 0.09 μM for B, with wide anti-proliferative effects.</p>Formule :C19H17Cl2N3O4SCouleur et forme :SolidMasse moléculaire :454.33G9a-IN-2
CAS :<p>G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).</p>Formule :C30H42N4O4Couleur et forme :SolidMasse moléculaire :522.68HDAC1/MAO-B-IN-1
CAS :<p>HDAC1/MAO-B-IN-1 is a selective Alzheimer’s research inhibitor with IC50s: HDAC1 (21.4 nM) & MAO-B (99 nM); crosses the blood-brain barrier.</p>Formule :C18H17ClN2O2Couleur et forme :SolidMasse moléculaire :328.79Tankyrase-IN-4
<p>Tankyrase-IN-4 is a potent inhibitor of tankyrase 1 (TNKS1), exhibiting an IC50 of 0.8 nM, and is utilized in cancer research.</p>Formule :C25H24N6O5Couleur et forme :SolidMasse moléculaire :488.5LP99
CAS :<p>LP99 is an epigenetic probe.</p>Formule :C26H30ClN3O4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :516.05TM6089
CAS :<p>TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.</p>Formule :C13H14N4O3SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :306.34FAK/aurora kinase-IN-1
CAS :<p>FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].</p>Formule :C23H24ClN7O3Couleur et forme :SolidMasse moléculaire :481.93BET bromodomain inhibitor 3
CAS :<p>BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT.</p>Formule :C18H17N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.35PRMT4-IN-1
CAS :<p>PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].</p>Formule :C23H28FN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.49PARP11 inhibitor ITK7
CAS :<p>ITK7 is a potent, selective PARP11 inhibitor with an IC50 of 14 nM, useful for cellular localization research.</p>Formule :C17H14N4OSCouleur et forme :SolidMasse moléculaire :322.38HDAC-IN-41
CAS :<p>HDAC-IN-41 is a selective class I HDAC inhibiting HDAC1, 2, & 3 with IC50: 0.62-1.46 µM; oral use; has NO-release.</p>Formule :C20H22N4O6SCouleur et forme :SolidMasse moléculaire :446.48BI-831266
CAS :<p>BI-831266 is a potent and selective Aurora kinase B inhibitor.</p>Formule :C27H38ClN7O2Couleur et forme :SolidMasse moléculaire :528.09KF 13218
CAS :<p>KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.</p>Formule :C20H20N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.38YUKA1
CAS :<p>YUKA1, a cell-permeable KDM5A inhibitor with a weak effect on KDM5C, increase H3K4me3 and inhibit the proliferation, prevent drug-resistant.</p>Formule :C13H16N4O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :292.36HDAC-IN-30
CAS :<p>HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.</p>Formule :C22H23N5O3Couleur et forme :SolidMasse moléculaire :405.45HDAC6-IN-14
<p>HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1,</p>Formule :C24H30FN3O4Couleur et forme :SolidMasse moléculaire :443.51JFD00244
CAS :<p>JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.</p>Formule :C30H26N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.54Y06036
CAS :<p>Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).</p>Formule :C16H15BrN2O5SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :427.27PRMT5-IN-2
CAS :<p>PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.</p>Formule :C17H16ClFN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.78NCD38
CAS :<p>NCD38 is a potent, selective LSD1 inhibitor.</p>Formule :C37H37ClF3N3O4Degré de pureté :98.21% - 98.86%Couleur et forme :SolidMasse moléculaire :680.16(Rac)-BAY1238097
CAS :<p>(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.</p>Formule :C25H33N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.56JAK-2/3-IN-2
CAS :<p>JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 & JAK3 inhibitor with IC50s of 23.85 nM (JAK2) & 18.9 nM (JAK3).</p>Formule :C19H19ClN2OSCouleur et forme :SolidMasse moléculaire :358.89EZM 2302
CAS :<p>EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.</p>Formule :C29H37ClN6O5Degré de pureté :97.47% - ≥98%Couleur et forme :SolidMasse moléculaire :585.09HDAC6-IN-11
CAS :<p>HDAC6-IN-11 (Compound 9) is a cancer cell growth blocker, selectively inhibiting HDAC6 (>300-fold) with an IC50 of 20.7 nM.</p>Formule :C19H16N2O4Couleur et forme :SolidMasse moléculaire :336.34HDAC8/BRPF1-IN-1
CAS :<p>Compound 23a, dual HDAC8/BRPF1 inhibitor: IC50 HDAC8 = 443 nM, Kd BRPF1 = 67 nM; weak against HDAC1/6.</p>Formule :C19H19N3O6SCouleur et forme :SolidMasse moléculaire :417.44OHM1
CAS :<p>OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53</p>Formule :C24H42N6O5Couleur et forme :SolidMasse moléculaire :494.63J1038
CAS :<p>J1038 is a novel Histone Deacetylase 8 (HDAC8) Inhibitor .</p>Formule :C10H10N2O3SCouleur et forme :SolidMasse moléculaire :238.26A2B57
CAS :<p>A2B57 is a selective SIRT2 inhibitor.</p>Formule :C22H19N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.42BRD4-BD1-IN-1
CAS :<p>BRD4-BD1-IN-1 (Compound 9a) is a BRD4-BD1 inhibitor(IC50= 38.20 μM).</p>Formule :C16H15BrN4O4Couleur et forme :SolidMasse moléculaire :407.22A2AAR/HDAC-IN-1
CAS :<p>A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.</p>Formule :C24H21N7O2Couleur et forme :SolidMasse moléculaire :439.47ARTD10/PARP10-IN-2
CAS :<p>ARTD10/PARP10-IN-2: A potent, non-selective PARP inhibitor, IC50: ARTD10/PARP10 (2.0μM), ARTD1/PARP1 (9.7μM).</p>Formule :C12H13N3O3Couleur et forme :SolidMasse moléculaire :247.25BNS
CAS :<p>BNS is a potent, prolyl-hydroxylase 2 (PHD2)-selective inhibitor.</p>Formule :C18H16N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.46MARK-IN-4
CAS :<p>MARK-IN-4 inhibits microtubule kinase (MARK) effectively (IC50: 1 nM), a target for Alzheimer's therapy.</p>Formule :C21H23N7OSCouleur et forme :SolidMasse moléculaire :421.52DCE_42
CAS :<p>DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.</p>Formule :C22H19N9O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.51JAK-IN-11
CAS :<p>JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.</p>Formule :C23H22FN5O4SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :483.52PARP1-IN-9
CAS :<p>PARP1-IN-9, potent PARP1 inhibitor with 30.51 nM IC50, outperforms Olaparib in anticancer efficacy.</p>Formule :C18H21N3O5Couleur et forme :SolidMasse moléculaire :359.38BRD4 Inhibitor-25
<p>BRD4 Inhibitor-25 blocks BRD4 (BD1: IC50 0.82 μM, BD2: 1.94 μM), induces cell death in ovarian cancer, used in cancer research.</p>Formule :C29H27N5O6SCouleur et forme :SolidMasse moléculaire :573.62CAY10685
CAS :<p>CAY10685, a CPTH2 analog with an alkyne for click reactions, inhibits NAT10 to study cancer-related chromatin changes.</p>Formule :C17H16ClN3SCouleur et forme :SolidMasse moléculaire :329.85DNMT3A-IN-1
CAS :<p>DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).</p>Formule :C30H38N6O4Couleur et forme :SolidMasse moléculaire :546.66NCDM-32B
CAS :<p>NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer.</p>Formule :C15H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.41AChE/HDAC-IN-1
CAS :<p>COX-2-IN-23 (A10) inhibits AChE & HDAC (IC50s: 0.12 & 0.23 nM), has antioxidant/metal-binding traits, and is used in Alzheimer's research.</p>Formule :C26H27ClN4O3Couleur et forme :SolidMasse moléculaire :478.97TYK2-IN-11
CAS :<p>TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.</p>Formule :C18H17N5O3SCouleur et forme :SolidMasse moléculaire :383.42SGC6870
CAS :<p>SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.</p>Formule :C23H21BrN2O2SCouleur et forme :SolidMasse moléculaire :469.39BRD4 Inhibitor-26
<p>BRD4 Inhibitor-26: blocks BRD4 (BD1 and BD2) with IC50 of 0.82 μM & 1.94 μM; used in ovarian cancer research.</p>Formule :C29H27N5O6SCouleur et forme :SolidMasse moléculaire :573.62103D5R
CAS :<p>103D5R selectively inhibits hif-1α, reducing its levels in hypoxia or with cobalt ions, dose- and time-dependently.</p>Formule :C20H21N3O2Couleur et forme :SolidMasse moléculaire :335.4MAT2A-IN-6
CAS :<p>MAT2A-IN-6 inhibits MAT2A, may slow MTAP-deficient cancer cell growth, has research value in cancer.</p>Formule :C18H13ClF3N3O3Couleur et forme :SolidMasse moléculaire :411.76CP-690550A
CAS :<p>Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.</p>Formule :C15H21N5O2Couleur et forme :SolidMasse moléculaire :303.36MZ-242
CAS :<p>MZ-242 is an effective and selective inhibitor of Sirt2.</p>Formule :C24H27N7O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :525.65Antiproliferative agent-17
CAS :<p>Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1].</p>Formule :C26H28N2OSCouleur et forme :SolidMasse moléculaire :416.58KDOAM-25
CAS :<p>KDOAM-25, a potent KDM5 inhibitor, enhances H3K4 methylation, hampers MM1S cell growth; IC50: 71 nM (5A), 19 nM (5B), 69 nM (5C/D).</p>Formule :C15H25N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :307.39HDAC6/8/BRPF1-IN-1
CAS :<p>HDAC6/8/BRPF1-IN-1 is a cancer-research inhibitor for HDAC6, HDAC8, BRPF1 with IC50: 344-908 nM and Kd: 175.2 nM.</p>Formule :C18H17N3O5SCouleur et forme :SolidMasse moléculaire :387.41UNC2327
CAS :<p>UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).</p>Formule :C14H17N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.38AA-CW236
CAS :<p>AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).</p>Formule :C17H16ClF3N4O2Couleur et forme :SolidMasse moléculaire :400.78NN-390
CAS :<p>NN-390: selective HDAC6 inhibitor, IC50 9.8 μM, blood-brain barrier penetrant, potential for metastatic group 3 neural tube cancer research.</p>Formule :C17H16F4N2O4SCouleur et forme :SolidMasse moléculaire :420.38EZH2-IN-9
CAS :<p>EZH2-IN-9 inhibits EZH2, targeting SET mutations linked to cancer by reducing H3K27me3 levels.</p>Formule :C28H32ClF2N3O5SCouleur et forme :SolidMasse moléculaire :596.09EZH2-IN-11
CAS :<p>EZH2-IN-11, a potent E2HZ inhibitor with potential for cancer treatment, is highlighted in patent WO2019204490A1.</p>Formule :C28H36ClN3O5SCouleur et forme :SolidMasse moléculaire :562.12Aurora Kinases-IN-2
CAS :<p>Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.</p>Formule :C22H18ClN5O3Couleur et forme :SolidMasse moléculaire :435.86DC-BPi-11
CAS :<p>DC-BPi-11 inhibits BPTF at IC50 698 nM and significantly reduces leukemia cell growth.</p>Formule :C20H23N5O2SCouleur et forme :SolidMasse moléculaire :397.49JS1310
CAS :<p>JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.</p>Formule :C23H22FN5O3Couleur et forme :SolidMasse moléculaire :435.45CypD inhibitor C-9
CAS :<p>CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.</p>Formule :C22H22N4O4S2Couleur et forme :SolidMasse moléculaire :470.56BET-IN-2
CAS :<p>BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).</p>Formule :C23H29N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.5PIM1-IN-6
CAS :<p>PIM1-IN-6 (5h) inhibits PIM-1 (IC50: 0.60 μM) and is cytotoxic to HCT-116 (IC50: 1.51 μM) and MCF-7 cells (IC50: 15.2 μM).</p>Formule :C21H18N6O4Couleur et forme :SolidMasse moléculaire :418.41TNKS-IN-41
CAS :<p>TNKS-IN-41 highly potent and selective inhibitor of tankyrase.</p>Formule :C24H22N10O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.5K00135
CAS :<p>K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.</p>Formule :C18H18N4ODegré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :306.36MC-1353
CAS :<p>MC-1353 is a potent, selective inhibitor of HDAC class I.</p>Formule :C16H16N2O3Couleur et forme :SolidMasse moléculaire :284.31PBRM1-BD2-IN-1
CAS :<p>PBRM1-BD2-IN-1: Selective PBRM1 inhibitor with Kd 0.7μM, IC50 0.2μM, useful in cancer research.</p>Formule :C17H19ClN2OCouleur et forme :SolidMasse moléculaire :302.84-iodo-SAHA
CAS :<p>4-Iodo-SAHA (1k), an oral HDAC inhibitor for cancer research, has EC50s from 0.12 to 1.3 μM across various cell lines.</p>Formule :C14H19IN2O3Couleur et forme :SolidMasse moléculaire :390.22HDAC1-IN-4
CAS :<p>HDAC1-IN-4 is a potent inhibitor of Plasmodium falciparum HDAC1 (PfHDAC1) with low cytotoxicity and antimalarial effects (IC50<5 nM).</p>Formule :C21H24BrClN6O2Couleur et forme :SolidMasse moléculaire :507.82JAK-IN-20
CAS :<p>JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.</p>Formule :C28H30FN7O2Couleur et forme :SolidMasse moléculaire :515.58PIM1-IN-7
CAS :<p>PIM1-IN-7 inhibits PIM-1 (IC50: 0.67μM), toxic to HCT-116/MCF-7 cells (IC50: 42.9/7.68μM).</p>Formule :C23H23N5OCouleur et forme :SolidMasse moléculaire :385.46HDAC/CK2-IN-1
CAS :<p>HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.</p>Formule :C15H18Br4N4O2Couleur et forme :SolidMasse moléculaire :605.95BRD4-BD1/2-IN-1
CAS :<p>BRD4-BD1/2-IN-1 efficiently blocks BRD4 BD-1/2 under 100 nM IC50 (US20150148375A1, cmpd 5).</p>Formule :C21H14F2N4O2Couleur et forme :SolidMasse moléculaire :392.36DPQ
CAS :<p>DPQ inhibits PARP-1, aids in neuroprotection, restores ATP, and lessens neuronal injury from NMDA.</p>Formule :C18H26N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.41AMPK activator 9
CAS :<p>AMPK activator 9 (ZM-6) is a potent α2β1γ1 agonist with an EC50 of 1.1 µM, potential for type 2 diabetes research.</p>Formule :C31H28F4N4O4Couleur et forme :SolidMasse moléculaire :596.57ART-IN-1
CAS :<p>ART-IN-1 (compound 7) is a selective inhibitor of PARP with IC 50 s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively [1].</p>Formule :C14H13NO2SCouleur et forme :SolidMasse moléculaire :259.32Peficitinib hydrochloride
CAS :<p>Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).</p>Formule :C18H23ClN4O2Couleur et forme :SolidMasse moléculaire :362.86VE-465
CAS :<p>VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.</p>Formule :C22H28N8OSCouleur et forme :SolidMasse moléculaire :452.58PRMT5-IN-17
CAS :<p>PRMT5-IN-17 is a PRMT5-blocking compound with anticancer properties, linked to epigenetic changes.</p>Formule :C26H33N7O2Couleur et forme :SolidMasse moléculaire :475.59HDAC/NAMPT-IN-1
CAS :<p>HDAC/NAMPT-IN-1 (compound 39h) simultaneously inhibits HDAC and NAMPT, exhibiting IC 50 values ranging from 0.72 to 37081 nM for HDAC and 1618 nM for NAMPT [1].</p>Formule :C19H21N5O2Couleur et forme :SolidMasse moléculaire :351.4IACS-9571 hydrochloride
CAS :<p>IACS-9571 hydrochloride: potent TRIM24/BRPF1 inhibitor; IC50 = 8 nM (TRIM24); Kd = 31 nM (TRIM24), 14 nM (BRPF1).</p>Formule :C32H43ClN4O8SCouleur et forme :SolidMasse moléculaire :679.22KDM2B-IN-4
CAS :<p>KDM2B-IN-4, from patent WO2016112284A1 as 182b, is a potent KDM2B inhibitor used in cancer research.</p>Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49CEP-8983
CAS :<p>CEP-8983 is a PARP inhibitor potentially for the treatment of solid tumours.</p>Formule :C18H14N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.32BRM/BRG1 ATP Inhibitor-4
CAS :<p>BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.</p>Formule :C25H32N6O3SCouleur et forme :SolidMasse moléculaire :496.62MAT2A-IN-7
CAS :<p>MAT2A-IN-7 inhibits MAT2A in various cancers, especially MTAP-deficient cancer cells, with potential for research use.</p>Formule :C17H13ClF3N3O2Couleur et forme :SolidMasse moléculaire :383.75Dihydro-5-azacytidine acetate
CAS :<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Formule :C10H18N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.27LT052
CAS :<p>LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.</p>Formule :C22H19N5O4SDegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :449.48Sirt2-IN-6
CAS :<p>Sirt2-IN-6 is a potent and selective inhibitor of SIRT2 (IC50: 0.815 μM) and can be used to study cancer.</p>Formule :C26H26N6O3SCouleur et forme :SolidMasse moléculaire :502.59BRD4884
CAS :<p>BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders.</p>Formule :C18H19FN2O2Degré de pureté :99.19% - 99.21%Couleur et forme :SolidMasse moléculaire :314.35Lorpucitinib
CAS :<p>Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.</p>Formule :C22H28N6O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :408.5KDM2/7-IN-1
CAS :<p>KDM2/7-IN-1 is a selective histone demethylase inhibitor (IC50s: 0.2–>120 μM) that inhibits HeLa and KYSE-150 cell proliferation, epigenetic and cancer.</p>Formule :C15H27NO4Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :285.38BETi-211
CAS :<p>BETi-211 is a selective inhibitor BET bromodomain.</p>Formule :C26H29N7O3Couleur et forme :SolidMasse moléculaire :487.55ZYJ-25e
CAS :<p>ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.</p>Formule :C30H40N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :584.66IND 1316
CAS :<p>IND 1316 is an activator of AMP-activated protein kinase (AMPK).</p>Formule :C22H17NO3Couleur et forme :SolidMasse moléculaire :343.38CCT077791
CAS :<p>CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research.</p>Formule :C9H5ClN2O3SDegré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :256.67ZIKV-IN-2
CAS :<p>ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.</p>Formule :C39H42O4Couleur et forme :SolidMasse moléculaire :574.75KU-0058684
CAS :<p>KU-0058684 is a potent PARP and DNA-PK inhibitors.</p>Formule :C19H14FN3O3Couleur et forme :SolidMasse moléculaire :351.33ML753286
CAS :<p>ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.</p>Formule :C20H25N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.43Trotabresib
CAS :<p>Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.</p>Formule :C21H21NO4SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :383.46JAK1-IN-4
CAS :<p>JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).</p>Formule :C26H32FN9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.59Y02224
CAS :<p>Y02224 is a BET inhibitor. It shows the reasonable antiproliferative effect on leukemia cells.</p>Formule :C20H17BrN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.33Dot1L-IN-5
CAS :<p>Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].</p>Formule :C23H19ClF2N8O5SCouleur et forme :SolidMasse moléculaire :592.96HAT-IN-1
CAS :<p>HAT-IN-1 is an inhibitor of HAT used in the research of cancer.</p>Formule :C23H18BrF4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.3Helenalin Acetate
CAS :<p>Helenalin Acetate: anti-inflammatory, anti-cancer, hinders C/EBPß and p300 cooperation.</p>Formule :C17H20O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.34HDAC-IN-45
CAS :<p>HDAC-IN-45, a small HDAC blocker, forms H-bonds with Y303 and shows anticancer properties; IC50 for HDAC1/2/3: 0.108/0.585/0.563 μM.</p>Formule :C25H20ClFN8OCouleur et forme :SolidMasse moléculaire :502.93DM-01
CAS :<p>DM-01 is a potent and selective inhibitor of EZH2.</p>Formule :C23H24F3N3O2Couleur et forme :SolidMasse moléculaire :431.45dBRD9-A
CAS :<p>Potent BRD9 degrader that binds selectively, fully degrades BRD9 at low doses, and hinders synovial sarcoma growth in vitro and in mice.</p>Formule :C42H49N7O8Couleur et forme :SolidMasse moléculaire :779.88PB118
<p>PB118 clears Aβ, boosts phagocytosis, enhances tubulin networks, reduces p-tau & inflammation in AD; HDAC6 IC50: 5.6 nM.</p>Formule :C18H19FN2O2Couleur et forme :SoildMasse moléculaire :314.35Dot1L-IN-7
CAS :<p>Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.</p>Formule :C23H27N9O2Couleur et forme :SolidMasse moléculaire :461.52CeMMEC2
CAS :<p>CeMMEC2, a novel inhibitor of BRD4, binds both the first and the second bromodomain of BRD4.</p>Formule :C14H19N5Couleur et forme :SolidMasse moléculaire :257.33(1S,2R)-Tranylcypromine hydrochloride
CAS :<p>(1S,2R)-Tranylcypromine hydrochloride ((1S,2R)-SKF 385), a potent antidepressant, functions by inhibiting both MAO and LSD1.</p>Formule :C9H12ClNCouleur et forme :SolidMasse moléculaire :169.651Guadecitabine sodium
CAS :<p>Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .</p>Formule :C18H24N9NaO10PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.407HDAC6-IN-46
CAS :<p>HDAC6-IN-46 (compound 12) is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 6.2 nM. It is utilized in research related to Alzheimer's disease.</p>Formule :C26H21N3O4Couleur et forme :SolidMasse moléculaire :439.46HDAC3-IN-T326
CAS :<p>HDAC3-IN-T326: potent, selective HDAC3 inhibitor, boosts NF-κB acetylation, activates latent HIV gene expression.</p>Formule :C21H18N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.47Gue1654
CAS :<p>Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.</p>Formule :C23H17N3OS3Degré de pureté :98.02% - 98.04%Couleur et forme :SolidMasse moléculaire :447.6LSD1-IN-6
CAS :<p>LSD1-IN-6, a potent LSD1 inhibitor (IC50: 123 nM), enhances H3K4me2 without altering LSD1 expression. Reversible.</p>Formule :C15H13BrN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.18SC-9
CAS :<p>SC-9 is a protein kinase C activator.</p>Formule :C22H24ClNO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.95PS432
CAS :<p>PS432 inhibits atypical PKCs, targets PIF-pocket, reduces tumors in mice sans side effects.</p>Formule :C25H19ClN2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :494.95SMYD2-IN-1
CAS :<p>SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).</p>Formule :C25H25Cl2F2N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.41Piribedil dihydrochloride
CAS :<p>dopamine agonist</p>Formule :C16H20Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.26Akt Inhibitor X
CAS :<p>Akt Inhibitor X is a cell-permeable and reversible inhibitor of Akt phosphorylation.</p>Formule :C20H25ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :344.88KDM5B-IN-3
CAS :<p>KDM5B-IN-3 inhibits KDM5B/JARID1B with IC50 of 9.32 μM, useful in gastric cancer studies.</p>Formule :C19H25ClN4O2Couleur et forme :SolidMasse moléculaire :376.88DDP-38003 dihydrochloride
CAS :<p>DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).</p>Formule :C21H28Cl2N4ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :423.38CID-4785700
CAS :<p>CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75</p>Formule :C22H23ClFN3O3Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :431.89Kgp-IN-1
CAS :<p>Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.</p>Formule :C19H24F4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.41PARP-1/2-IN-1
CAS :<p>PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).</p>Formule :C24H27FN4O3Couleur et forme :SolidMasse moléculaire :438.49NSC-636819
CAS :<p>NSC-636819 is a novel inhibitor of KDM4A/KDM4B.</p>Formule :C22H12Cl4N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.15M-110
CAS :<p>M-110 selectively targets PIM kinases, best at PIM-3 (IC50=47nM), and inhibits prostate cancer cell growth (IC50=0.6-0.9μM).</p>Formule :C22H28ClN5O3Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :445.94MI-1
CAS :<p>MI-1 inhibits Menin-MLL interaction with an IC 50 of 1.9 μM [1].</p>Formule :C19H25N5S2Couleur et forme :SolidMasse moléculaire :387.57
