Altération de l'ADN/réparation de l'ADN
Les inhibiteurs de la réparation des dommages à l'ADN sont des composés qui interfèrent avec les processus impliqués dans la détection et la réparation des dommages à l'ADN. Ces inhibiteurs sont essentiels pour étudier les mécanismes de la stabilité génomique, de la mutagenèse et de la réponse aux dommages à l'ADN. Ils sont également importants dans la recherche sur le cancer, car de nombreuses tumeurs dépendent de voies spécifiques de réparation de l'ADN pour survivre. En inhibant ces voies, les inhibiteurs de la réparation des dommages à l'ADN peuvent améliorer l'efficacité de la chimiothérapie et de la radiothérapie. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité de la réparation des dommages à l'ADN pour soutenir vos recherches en biologie moléculaire, oncologie et pharmacologie.
Sous-catégories appartenant à la catégorie "Altération de l'ADN/réparation de l'ADN"
- ATM/ATR(71 produits)
- Alkylation de l'ADN(11 produits)
- Méthyltransférase de l’ADN(421 produits)
- Gyrase de l’ADN(11 produits)
- ADN-PK(51 produits)
- MTH1(1 produits)
- Antimétabolite nucléosidique/analogue(1.388 produits)
- Transcriptase inverse(43 produits)
- Sirtuine(88 produits)
- Télomérase(33 produits)
- Topoisomérase(136 produits)
Affichez 3 plus de sous-catégories
957 produits trouvés pour "Altération de l'ADN/réparation de l'ADN"
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NSC 370284
CAS :<p>NSC 370284 inhibits STAT3/5, reducing AML cell viability with TET1 overexpression in vitro/in vivo.</p>Formule :C21H25NO6Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :387.43PARP1-IN-8
CAS :<p>PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) is an effective inhibito of PARP1 (IC50 = 97 nM).</p>Formule :C23H18ClN3O2Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :403.86TAK1 inhibitor
CAS :<p>TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.</p>Formule :C22H19ClN6O2SDegré de pureté :98%Couleur et forme :SoildMasse moléculaire :466.94Wistin
CAS :<p>Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .</p>Formule :C23H24O10Couleur et forme :SolidMasse moléculaire :460.43Suprastat
CAS :<p>Suprastat is an HDAC6 inhibitor used in silico simulations.</p>Degré de pureté :98%Couleur et forme :Solid1-Methyladenosine-d3
<p>1-Methyladenosine-d3 hydrochloride is the hydrochloride salt form of deuterium-labeled 1-Methyladenosine. This compound is a modification of RNA that serves as a biomarker for tumors, with elevated levels in the body linked to cancer development. Upon methylation, 1-Methyladenosine upregulates the expression of PPARδ, regulates cholesterol metabolism, and activates the Hedgehog signaling pathway, thereby driving the onset of liver tumors.</p>Couleur et forme :Odour SolidPyronaridine tetraphosphate
CAS :<p>Pyronaridine tetraphosphate is a DNA topoisomerase 2 inhibitor with antimalarial and antitumor activity for the treatment of P. falciparum infection.</p>Formule :C29H44ClN5O18P4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :910.03TNKS-2-IN-1
CAS :<p>TNKS-2-IN-1 inhibits TNKS1/2 (IC50: 259/1100 nM), has antimicrobial effects on E. coli/S. aureus, and blocks NLRP3/IL-1β release (IC50: 5 μM).</p>Formule :C14H9N3O3Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :267.24Banoxantrone (D12)
CAS :<p>Banoxantrone D12, deuterium-labeled version, reduces to AQ4 - a stable DNA-targeting topoisomerase II inhibitor.</p>Formule :C22H28N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.55PR-104 sodium
CAS :<p>PR-104 sodium: hypoxia-activated, tumor-targeting pre-prodrug; turns into PR-104A for research.</p>Formule :C14H19BrN4NaO12PSCouleur et forme :SolidMasse moléculaire :601.25ARN24139
<p>ARN24139: a topoisomerase II poison; IC50=7.3μM. Inhibits DU145, HeLa, A549 cell growth; IC50s=4.7, 3.8, 3.1μM.</p>Couleur et forme :SolidWAY-323061
CAS :<p>WAY-323061 is a SIRT2 inhibitor.</p>Formule :C25H21N5O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :455.53Elomotecan hydrochloride
CAS :<p>Elomotecan hydrochloride (BN 80927), a potent hCPT analog, inhibits topoisomerases I/II, outperforming other anticancer drugs.</p>Formule :C29H33Cl2N3O4Couleur et forme :SolidMasse moléculaire :558.5Leriglitazone
CAS :<p>Leriglitazone, pioglitazone's metabolite, is a PPARγ agonist (Ki:1.2μM, EC50:680nM), enhancing transcription and stabilizing AF-2.</p>Formule :C19H20N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :372.44PB200
<p>PB200, an HDAC6 inhibitor, demonstrates significant antidepressant effects with an IC50 value of 1.97 nM. It operates by normalizing aberrant HDAC6 expression levels and alleviating neuroinflammation.</p>Formule :C17H18FN3O2Couleur et forme :SolidMasse moléculaire :315.34CA-M11
<p>CA-M11 (compound CA-M11) is capable of entering the liver's bile salt transport system to release Mirin.</p>Formule :C34H46N2O6SCouleur et forme :SolidMasse moléculaire :610.80SCR7
CAS :<p>SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).</p>Formule :C18H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.4HDAC9-IN-1
<p>HDAC9-IN-1 (Compound 7g) is a potent inhibitor of HDAC9, exhibiting an IC50 of 40 nM. This compound effectively suppresses various human cancer cell lines, induces apoptosis, modulates caspase-related proteins and p38, and results in DNA damage.</p>Formule :C27H22N4O3SCouleur et forme :SolidMasse moléculaire :482.55AsCas12a Nuclease
<p>AsCas12a Nuclease is a CRISPR nuclease capable of specifically cleaving double-stranded DNA. It is used in gene editing research.</p>PARP10-IN-3
CAS :<p>PARP10-IN-3: selective inhibitor for mono-ADP-ribotransferase PARP10 (IC50: 480nM), also affects PARP2 and PARP15 (IC50: 1.7μM).</p>Formule :C14H12N2O3Degré de pureté :99.41%Couleur et forme :SoildMasse moléculaire :256.26DNA Damage & Repair Compound Library
<p>A unique collection of xnum DNA Damage &amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Couleur et forme :Odour SolidGimatecan HCl
<p>Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.</p>Formule :C25H26ClN3O5Degré de pureté :97.04%Couleur et forme :SoildMasse moléculaire :483.9423-epi-26-Deoxyactein
CAS :<p>23-epi-26-Deoxyactein is a naturally occurring compound exhibiting anti-obesity and anti-cancer properties when administered orally [1] [2] [3].</p>Formule :C37H56O10Couleur et forme :SolidMasse moléculaire :660.83Lucidin primeveroside
CAS :<p>Lucidin primeveroside (Lucidin 3-O-primeveroside) is a natural product isolated from the root powder of akane (Rubia akane) and can be used as a coloring agent</p>Formule :C26H28O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.49DMT-dU-CE Phosphoramidite
CAS :<p>DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.</p>Formule :C39H47N4O8PDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :730.79Tibesaikosaponin V
CAS :<p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>Formule :C42H68O15Couleur et forme :SolidMasse moléculaire :812.98Dichlorogelignate
CAS :<p>Dichlorogelignate (compound 4) acts as a selective inhibitor of topoisomerase II (Topo II), achieving 100% inhibition at 50 μM [1].</p>Formule :C32H34O18Couleur et forme :SolidMasse moléculaire :706.6Ketopioglitazone
CAS :<p>Ketopioglitazone is an active metabolite of pioglitazone.</p>Formule :C19H18N2O4SCouleur et forme :SolidMasse moléculaire :370.42PNU-142586
CAS :<p>PNU-142586 is a bio-active chemical.</p>Formule :C16H20FN3O6Couleur et forme :SolidMasse moléculaire :369.34MST-312
CAS :<p>MST-312, a telomerase inhibitor derived from green tea's EGCG, has research potential in cancer, including MM.</p>Formule :C20H16N2O6Degré de pureté :99.61% - 99.68%Couleur et forme :SolidMasse moléculaire :380.35Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Formule :C21H22N2O6Couleur et forme :SolidMasse moléculaire :398.409HDAC3/8 ligand-1
<p>HDAC3/8 ligand-1 (compound 40) serves as a ligand for the target protein of PROTAC, utilized in the synthesis of YX968.</p>Formule :C14H22N4OCouleur et forme :SolidMasse moléculaire :262.35CH-0793076
CAS :<p>CH-0793076: hexacyclic camptothecin, TP300 metabolite, targets BCRP, inhibits DNA topo I (IC50: 2.3 μM).</p>Formule :C26H26N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.51SMPB Crosslinker
CAS :<p>SMPB crosslinker reacts with sulfhydryl/amino groups, has a longer chain than MBS, and a non-cleavable spacer arm.</p>Formule :C18H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.3315-LOX-IN-2
<p>15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.</p>Couleur et forme :Odour Solid20-carboxy Arachidonic Acid
CAS :<p>20-COOH-AA, 20-HETE metabolite, inhibits kidney ion transport, relaxes constricted vessels, and activates PPARα/γ.</p>Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.456Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)
CAS :<p>3-Methoxybenzamide derivative modulates sirtuins; may boost cell lifespan and treat diseases.</p>Formule :C20H15N3O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :361.42PARP1-IN-33
CAS :<p>PARP1-IN-33 (Example 6) is a PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates protective effects on retinal cells, exhibiting an EC50 of 0.02 nM in inhibiting hydrogen peroxide-induced MTS activity in human retinal pigment epithelial cells.</p>Formule :C23H24ClFN4OCouleur et forme :SolidMasse moléculaire :426.91SpCas9 D10A Nickase
<p>SpCas9 D10A Nickase is a variant of the Cas9 protein. This mutation retains the functionality of one cleavage domain of the Cas9 nuclease, allowing it to specifically nick a target single strand. Additionally, SpCas9 D10A Nickase is effective in reducing off-target effects.</p>HDAC-IN-78
<p>HDAC-IN-78 (compound 66a) is an HDAC inhibitor utilized for cancer research.</p>Couleur et forme :Odour SolidnTZDpa
CAS :<p>nTZDpa is an antibiotic with antimicrobial activity.</p>Formule :C22H15Cl2NO2SCouleur et forme :SolidMasse moléculaire :428.33DNMT1/HDAC-IN-1
<p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>Couleur et forme :Odour SolidDB1255 2TFA
<p>DB1255 2TFA is an ERG/DNA binding inhibitor with an unusual and potent monomer binding pattern at the minor groove site for the study of genetic disorders.</p>Formule :C26H20F6N4O4S2Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :630.58Elomotecan
CAS :<p>Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II.Cost-effective and quality-assured.</p>Formule :C29H32ClN3O4Couleur et forme :SolidMasse moléculaire :522.04ATM Inhibitor-9
<p>ATM Inhibitor-9 (Compd 7a) is a potent inhibitor of ATM kinase, exhibiting an IC50 value of 5 nM, and is utilized in cancer research [1].</p>Formule :C25H32N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.56Cytidine 5'-diphosphate trisodium salt
CAS :<p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>Formule :C9H15N3Na3O11P2Degré de pureté :99.55%Couleur et forme :White Crystalline PowderMasse moléculaire :472.15SIRT-IN-5
<p>SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation of multiple myeloma cells. This differentiation is associated with increased expression of the differentiation antigens CD49e and human immunoglobulin light chains λ and κ.</p>Couleur et forme :Odour SolidChimmitecan
CAS :<p>Chimmitecan ((S)-9-Allyl-10-hydroxycamptothecin) is a potent inhibitor of topoisomerase I and displays outstanding activity in vitro and in vivo.</p>Formule :C23H20N2O5Degré de pureté :98.35%Couleur et forme :SoildMasse moléculaire :404.42Becatecarin
CAS :<p>Becatecarin, water-soluble and anti-cancer, inhibits topoisomerases I/II and induces DNA cleavage and apoptosis; has myelosuppressive effects; ABCG2 substrate.</p>Formule :C33H34Cl2N4O7Couleur et forme :SolidMasse moléculaire :669.56IC 86621
CAS :<p>IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM for repair.</p>Formule :C12H15NO3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :221.25GSK3735967
CAS :<p>GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.</p>Formule :C25H31N7OSCouleur et forme :SolidMasse moléculaire :477.62Phosphoramide mustard
CAS :<p>Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.</p>Formule :C4H11Cl2N2O2PDegré de pureté :93.00%Couleur et forme :SolidMasse moléculaire :221.02MS9024
<p>MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.</p>Couleur et forme :Odour SolidCarboxy-pyridostatin 2HCl
<p>Carboxy-pyridostatin 2HCl has potential antitumor activity with high affinity for DNA at DNA G4s.</p>Formule :C35H36Cl2N10O7Degré de pureté :97.12% - 99.10%Couleur et forme :SoildMasse moléculaire :779.63TUG-499
CAS :<p>TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors</p>Formule :C16H11Cl2NO2Degré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :320.17Colibactin 742
CAS :<p>Colibactin 742, a stable derivative of colibactin, efficiently induces DNA interstrand cross-links, activates the Fanconi Anemia DNA repair pathway, and leads</p>Formule :C37H42N8O5S2Couleur et forme :SolidMasse moléculaire :742.91MPT0B390
CAS :<p>MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.</p>Formule :C17H17N3O5SDegré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :375.4GpC Methyltransferase
<p>GpC Methyltransferase (GpC) is an enzyme that methylates DNA, specifically targeting cytosine residues within GpC dinucleotides of non-nucleosomal DNA in vitro.</p>Stearolic acid
CAS :<p>Stearolic acid is a useful organic compound for research related to life sciences. The catalog number is T124753 and the CAS number is 506-24-1.</p>Formule :C18H32O2Couleur et forme :SolidMasse moléculaire :280.452Gancaonin L
CAS :<p>Gancaonin L is a natural product that can be used as a reference standard. The CAS number of Gancaonin L is 129145-50-2.</p>Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.3589-Hydroxyellipticin free base
CAS :<p>9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine.</p>Formule :C17H14N2OCouleur et forme :SolidMasse moléculaire :262.312'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS :<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Formule :C9H13ClFN3O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :281.67O6BTG-octylglucoside
CAS :<p>O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).</p>Formule :C24H34BrN5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :616.53Heptaplatin
CAS :<p>Heptaplatin, an anticancer platinum compound, counters many cancers, including cisplatin-resistant types, with a 17% response rate and tolerable toxicity.</p>Formule :C11H20N2O6PtCouleur et forme :White Crystalline PowderMasse moléculaire :471.36SIRT5 inhibitor 3
CAS :<p>SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .</p>Formule :C22H12FN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.35Phosphoramide mustard cyclohexanamine
CAS :<p>Phosphoramide mustard cyclohexanamine is active metabolite of cyclophosphamide, an alkylating agent that cross-links DNA strands,causes cell death, antitumor.</p>Formule :C10H24Cl2N3O2PDegré de pureté :95%Couleur et forme :SolidMasse moléculaire :320.2(R)-GSK-3685032
CAS :<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Formule :C22H24N6OSCouleur et forme :SolidMasse moléculaire :420.54(4-NH2)-Exatecan
CAS :<p>(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).</p>Formule :C23H21N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :403.43BRD7586
CAS :<p>BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.</p>Formule :C17H14ClN3O3S2Degré de pureté :97.70% - 99.03%Couleur et forme :SolidMasse moléculaire :407.89VK-1727
<p>VK-1727 inhibits EBNA1 DNA binding, reducing proliferation of EBV-positive cells while sparing EBV-negative cells, useful for multiple sclerosis research.</p>Formule :C29H25NO4Degré de pureté :98.074%Couleur et forme :SolidMasse moléculaire :451.51Banoxantrone dihydrochloride
CAS :<p>Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.</p>Formule :C22H30Cl2N4O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :517.4Gepotidacin
CAS :<p>Gepotidacin is a triazaacenaphthylene antibacterial inhibiting bacterial type II topoisomerase with lower resistance potential than fluoroquinolones.</p>Formule :C24H28N6O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :448.52HDAC-IN-4
CAS :<p>HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.</p>Formule :C20H21N3O2Couleur et forme :SolidMasse moléculaire :335.45'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAS :<p>5'-O-DMT-dU, a dUTPase inhibitor (Ki > 1 mM) for E. coli, is used in DNA synthesis.</p>Formule :C30H30N2O7Couleur et forme :SolidMasse moléculaire :530.57Gatifloxacin mesylate
CAS :<p>Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.</p>Formule :C20H26FN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.5AMA-37
CAS :<p>AMA-37 is a selective, reversible, and ATP-competitive DNA-PK inhibitor.</p>Formule :C17H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :283.32Daun02
CAS :<p>Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.</p>Formule :C41H44N2O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :884.79RPR121056
CAS :<p>RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.</p>Formule :C33H38N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :618.68Gatifloxacin sesquihydrate
CAS :<p>Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia.</p>Formule :C19H24FN3O5Couleur et forme :SolidMasse moléculaire :393.41Methyl methanesulfonate (Standard)
CAS :<p>Methyl methanesulfonate (Standard) is a standard material used in the analysis of methyl methanesulfonate, typically referenced in its research and analysis.</p>Formule :C2H6O3SCouleur et forme :SolidMasse moléculaire :110.13(R)-(+)-Bay-K-8644
CAS :<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Formule :C16H15F3N2O4Degré de pureté :96.51% - 96.51%Couleur et forme :SolidMasse moléculaire :356.3Telomerase-IN-3
CAS :<p>Telomerase-IN-3 is an inhibitor of telomerase.</p>Formule :C19H16ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.82CP-868388 free base
CAS :<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Formule :C26H33NO5Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :439.54Epitalon
CAS :<p>Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.</p>Formule :C14H22N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.35Balaglitazone
CAS :<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Formule :C20H17N3O4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :395.43Succinic acid sodium
CAS :<p>Succinic acid sodium is an orally active anxiolytic.</p>Formule :C4H6O4·xNaCouleur et forme :SolidBRD7116
CAS :<p>BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.</p>Formule :C28H36N2O4SDegré de pureté :99.69% - 99.91%Couleur et forme :SolidMasse moléculaire :496.66PTGR2-IN-1
CAS :<p>PTGR2-IN-1 is a potent inhibito of PTGR2r. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.</p>Formule :C19H22N2O2Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :310.39YK-3-237
CAS :<p>YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative</p>Formule :C19H21BO7Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :372.18Pamiparib
CAS :<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Formule :C16H15FN4ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :298.31Pixantrone dimaleate
CAS :<p>Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.</p>Formule :C25H27N5O10Degré de pureté :98.70% - 99.11%Couleur et forme :SolidMasse moléculaire :557.21FIT-039
CAS :<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Formule :C17H18FN3SDegré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :315.41MC1568
CAS :<p>MC1568 is a specific HDAC inhibitor for maize HD1-A (IC50: 100 nM, in a cell-free assay). It is 34-fold more selective for HD1-A than HD1-B.</p>Formule :C17H15FN2O3Degré de pureté :89.82% - ≥95%Couleur et forme :SolidMasse moléculaire :314.31BYK204165
CAS :<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Formule :C15H12N2O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :252.27Niraparib
CAS :<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39AK-7
CAS :<p>AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.</p>Formule :C19H21BrN2O3SDegré de pureté :98.43% - 99.34%Couleur et forme :SolidMasse moléculaire :437.35Ciprofloxacin hydrochloride monohydrate
CAS :<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Formule :C17H21ClFN3O4Degré de pureté :99.23% - 99.85%Couleur et forme :White Or Yellowish Crystalline PowderMasse moléculaire :385.82Remetinostat
CAS :<p>Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell</p>Formule :C16H21NO6Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :323.34PJ34
CAS :<p>PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.</p>Formule :C17H17N3O2Degré de pureté :95.05% - 99.85%Couleur et forme :SolidMasse moléculaire :295.34Resminostat hydrochloride
CAS :<p>Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent</p>Formule :C16H20ClN3O4SDegré de pureté :97.63% - 99.68%Couleur et forme :SolidMasse moléculaire :385.86L67
CAS :<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formule :C16H14Br2N4O4Degré de pureté :98.34% - 99.56%Couleur et forme :SolidMasse moléculaire :486.11Fluzoparib
CAS :<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Formule :C22H16F4N6O2Degré de pureté :98.53% - 99.63%Couleur et forme :SolidMasse moléculaire :472.4SRT1720 hydrochloride
CAS :<p>SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s: 37 μM/300 μM).</p>Formule :C25H24ClN7OSDegré de pureté :98% - 99.93%Couleur et forme :SolidMasse moléculaire :506.22Pyridostatin TFA
CAS :<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.71Suramin Sodium Salt
CAS :<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Formule :C51H34N6Na6O23S6Degré de pureté :97.47% - 99.97%Couleur et forme :WhiteMasse moléculaire :1429.15Darglitazone Sodium
CAS :<p>Darglitazone Sodium, an oral PPAR-γ agonist, aids type II diabetes study by regulating glucose and lipids.</p>Formule :C23H21N2NaO4SCouleur et forme :SolidMasse moléculaire :444.48BGP-15
CAS :<p>BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.</p>Formule :C14H24Cl2N4O2Degré de pureté :98.17% - 99.89%Couleur et forme :SolidMasse moléculaire :351.27Citarinostat
CAS :<p>ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.</p>Formule :C24H26ClN5O3Degré de pureté :98.06% - 99.06%Couleur et forme :SolidMasse moléculaire :467.95Bisantrene
CAS :<p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>Formule :C22H22N8Degré de pureté :96.07% - 98.57%Couleur et forme :SolidMasse moléculaire :398.46RHPS4
CAS :<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Formule :C22H17F2N2·CH3O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :458.48Thiacloprid
CAS :<p>Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.</p>Formule :C10H9ClN4SDegré de pureté :98.66% - 99.95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :252.72Rabdosiin
CAS :<p>Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.</p>Formule :C36H30O16Degré de pureté :98.64% - 99.49%Couleur et forme :SolidMasse moléculaire :718.61PIK-75 hydrochloride
CAS :<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Formule :C16H14BrN5O4S·HClDegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :488.74Pentamidine dihydrochloride
CAS :<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Formule :C19H26Cl2N4O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :413.34JW 55
CAS :<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Formule :C25H26N2O5Degré de pureté :99.31% - 99.76%Couleur et forme :SolidMasse moléculaire :434.48Tretazicar
CAS :<p>CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.</p>Formule :C9H8N4O5Degré de pureté :99.41% - 99.7%Couleur et forme :SolidMasse moléculaire :252.18Coralyne chloride
CAS :<p>Coralyne chloride is a protoberberine with strong anticancer activity.</p>Formule :C22H22ClNO4Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :399.87Adenine hemisulfate
CAS :<p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>Formule :(C5H5N5)·H2SO4Degré de pureté :99.48%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :368.33Selisistat S-enantiomer
CAS :<p>Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.</p>Formule :C13H13ClN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :248.71AZD 6482
CAS :<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formule :C22H24N4O4Degré de pureté :99.79% - 99.95%Couleur et forme :SolidMasse moléculaire :408.45NPC 15199
CAS :<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Formule :C21H23NO4Degré de pureté :99.93% - 99.94%Couleur et forme :White Crystalline PowderMasse moléculaire :353.41Genz-644282
CAS :<p>Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.</p>Formule :C22H21N3O5Degré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :407.42Pentamidine
CAS :<p>Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor</p>Formule :C19H24N4O2Degré de pureté :98.64% - 99.67%Couleur et forme :Crystallizes As Colorless Plates From Water SolidMasse moléculaire :340.42AG-494
CAS :<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Formule :C16H12N2O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :280.28TIQ-A
CAS :<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Formule :C11H7NOSDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :201.24AZD-2461
CAS :<p>AZD2461 is a novel PARP inhibitor.</p>Formule :C22H22FN3O3Degré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :395.43Clofibrate
CAS :<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Formule :C12H15ClO3Degré de pureté :98.77%Couleur et forme :Oil LiquidMasse moléculaire :242.70Pyridostatin
CAS :<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Formule :C31H32N8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.64TMPyP4 tosylate
CAS :<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formule :C72H66N8O12S4Degré de pureté :98.61% - 99.85%Couleur et forme :SolidMasse moléculaire :1363.6UPF 1069
CAS :<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formule :C17H13NO3Degré de pureté :98.80% - 99.88%Couleur et forme :SolidMasse moléculaire :279.29KU-57788
CAS :<p>NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).</p>Formule :C25H19NO3SDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :413.49EDO-S101
CAS :<p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>Formule :C19H28Cl2N4O2Degré de pureté :98.02% - 99.44%Couleur et forme :SolidMasse moléculaire :415.36PI3K-IN-1
CAS :<p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>Formule :C31H29N5O6SDegré de pureté :97.03% - 98%Couleur et forme :SolidMasse moléculaire :599.66RK-287107
CAS :<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Formule :C22H26F2N4O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :416.46SCR130
CAS :<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Formule :C19H13Cl2N3O2SDegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :418.3PARP1-IN-5 dihydrochloride
CAS :<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Formule :C25H26Cl2N2O5SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :537.46OUL35
CAS :<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Formule :C14H12N2O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :256.26Furegrelate
CAS :<p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>Formule :C15H11NO3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :253.25AZ32
CAS :<p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>Formule :C20H16N4ODegré de pureté :98.68% - 99.68%Couleur et forme :SolidMasse moléculaire :328.37AZ9482
CAS :<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formule :C26H22N6O2Degré de pureté :99.18% - 99.86%Couleur et forme :SolidMasse moléculaire :450.49DR2313
CAS :<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Formule :C8H10N2OSDegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :182.24VAL-083
CAS :<p>VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.</p>Formule :C6H10O4Degré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :146.14E7449
CAS :<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Formule :C18H15N5ODegré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :317.34Pixantrone hydrochloride
CAS :<p>Pixantrone hydrochloride is a topoisomerase II inhibitor and DNA intercalator with anti-tumor properties.</p>Formule :C17H20ClN5O2Couleur et forme :SolidMasse moléculaire :361.83Methotrexate disodium
CAS :<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formule :C20H20N8Na2O5Degré de pureté :99.77% - 99.96%Couleur et forme :SolidMasse moléculaire :498.4NKL 22
CAS :<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Formule :C19H23N3O2Degré de pureté :96.16% - 96.24%Couleur et forme :SolidMasse moléculaire :325.4Carmustine
CAS :<p>Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.</p>Formule :C5H9Cl2N3O2Degré de pureté :98% - 99.91%Couleur et forme :Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)Masse moléculaire :214.05AGK7
CAS :<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Formule :C23H13Cl2N3O2Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :434.27AZD-7648
CAS :<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Formule :C18H20N8O2Degré de pureté :99.03% - 99.85%Couleur et forme :SolidMasse moléculaire :380.4Xanthosine 5'-monophosphate sodium salt
CAS :<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Formule :C10H11N4Na2O9PDegré de pureté :99% - 99.77%Couleur et forme :SolidMasse moléculaire :408.17Pirarubicin
CAS :<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formule :C32H37NO12Degré de pureté :97.80% - 99.15%Couleur et forme :Red Crystalline PowderMasse moléculaire :627.64Levofloxacin hydrochloride
CAS :<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formule :C18H21ClFN3O4Degré de pureté :99.78% - 99.98%Couleur et forme :SolidMasse moléculaire :397.89-Hydroxycamptothecin
CAS :<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Formule :C20H16N2O5Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :364.35Ganciclovir sodium
CAS :<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formule :C9H13N5NaO4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :278.22Silver sulfadiazine
CAS :<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formule :C10H9AgN4O2SDegré de pureté :99.04% - 99.58%Couleur et forme :SolidMasse moléculaire :357.14Deoxycytidine triphosphate
CAS :<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Formule :C9H16N3O13P3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :467.16AZ6102
CAS :<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Formule :C25H28N6ODegré de pureté :97.98% - 99.91%Couleur et forme :SolidMasse moléculaire :428.53MK-4827 Racemate
CAS :<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Formule :C19H20N4ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :320.39LMK-235
CAS :<p>LMK-235 is a potent HDAC inhibitor, and is used in cancer research.</p>Formule :C15H22N2O4Degré de pureté :98.18% - 99.68%Couleur et forme :SolidMasse moléculaire :294.35Altretamine hydrochloride
CAS :<p>Altretamine hydrochloride is an alkylating antineoplastic agent.</p>Formule :C9H19ClN6Couleur et forme :SolidMasse moléculaire :246.74Ensulizole
CAS :<p>Ensulizole, a water-soluble UV absorber, damages DNA by generating ROS under UV light, and absorbs UVB and some UVA.</p>Formule :C13H10N2O3SDegré de pureté :99.79%Couleur et forme :White To Pale Beige Solid PowderMasse moléculaire :274.30EIDD-1931
CAS :<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formule :C9H13N3O6Degré de pureté :99.14% - 99.73%Couleur et forme :SolidMasse moléculaire :259.22CXD101
CAS :<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Formule :C24H29N5ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :403.522',3',5'-triacetyl-5-Azacytidine
CAS :<p>2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.</p>Formule :C14H18N4O8Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :370.31AG14361
CAS :<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Formule :C19H20N4ODegré de pureté :98.7% - 99.93%Couleur et forme :SolidMasse moléculaire :320.391-Oleoyl lysophosphatidic acid sodium
CAS :<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Formule :C21H40O7P·NaDegré de pureté :98.75% - 99.24%Couleur et forme :SolidMasse moléculaire :458.51GW9662
CAS :<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formule :C13H9ClN2O3Degré de pureté :98% - 99.95%Couleur et forme :Off-White SolidMasse moléculaire :276.681,4-Naphthoquinone
CAS :<p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>Formule :C10H6O2Degré de pureté :99.24% - 99.56%Couleur et forme :SolidMasse moléculaire :158.15M344
CAS :<p>M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.</p>Formule :C16H25N3O3Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :307.39SRT 1720
CAS :<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Formule :C25H23N7OSDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :469.56CM-579 trihydrochloride
<p>CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.</p>Formule :C29H43Cl3N4O3Couleur et forme :SolidMasse moléculaire :602.04NU 7026
CAS :<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Formule :C17H15NO3Degré de pureté :99.51% - >99.99%Couleur et forme :SolidMasse moléculaire :281.31NU1025
CAS :<p>NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.</p>Formule :C9H8N2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :176.17Gatifloxacin hydrochloride
CAS :<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Formule :C19H23ClFN3O4Degré de pureté :99.85% - 99.89%Couleur et forme :SolidMasse moléculaire :411.86SirReal2
CAS :<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Formule :C22H20N4OS2Degré de pureté :98.96% - 99.75%Couleur et forme :SolidMasse moléculaire :420.551-Hydroxyanthraquinone
CAS :<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Formule :C14H8O3Degré de pureté :99.56%Couleur et forme :Orange Red Needles Red-Orange To Fine Yellow CrystalsMasse moléculaire :224.21ML216
CAS :<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Formule :C15H9F4N5OSDegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :383.32NMS-P118
CAS :<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Formule :C20H24F3N3O2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :395.42Zebularine
CAS :<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Formule :C9H12N2O5Degré de pureté :99.04% - >99.99%Couleur et forme :SolidMasse moléculaire :228.2Thymidine
CAS :<p>Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.</p>Formule :C10H14N2O5Degré de pureté :99.64% - 99.86%Couleur et forme :White To Off-White Solid CrystallineMasse moléculaire :242.23Palifosfamide tromethamine
CAS :<p>Palifosfamide, a less toxic ifosfamide metabolite, is a DNA-alkylating anticancer agent.</p>Formule :C8H22Cl2N3O5PCouleur et forme :SolidMasse moléculaire :342.16Azemiglitazone
CAS :<p>Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.</p>Formule :C19H17NO5SDegré de pureté :98.29% - 99.6%Couleur et forme :SolidMasse moléculaire :371.41UBCS039
CAS :<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Formule :C16H13N3Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :247.29SW-100
CAS :<p>SW-100 is a potent HDAC6 inhibitor with 2.3 nM IC50, highly selective (>1000-fold), can cross blood-brain-barrier.</p>Formule :C17H17ClN2O2Degré de pureté :98.34% - 98.47%Couleur et forme :SolidMasse moléculaire :316.78GSK3685032
CAS :<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formule :C22H24N6OSDegré de pureté :98.56% - 99.49%Couleur et forme :SolidMasse moléculaire :420.53L-778123 hydrochloride
CAS :<p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>Formule :C22H21Cl2N5ODegré de pureté :93.93% - 98.51%Couleur et forme :SolidMasse moléculaire :442.34Indotecan
CAS :<p>Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).</p>Formule :C26H26N2O7Degré de pureté :97% - 98%Couleur et forme :SolidMasse moléculaire :478.49Hinokitiol
CAS :<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Formule :C10H12O2Degré de pureté :99.49% - 99.67%Couleur et forme :SolidMasse moléculaire :164.2PI-3065
CAS :<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Formule :C27H31FN6OSDegré de pureté :99.84% - ≥95%Couleur et forme :SolidMasse moléculaire :506.64Senaparib
CAS :<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Formule :C24H20F2N6O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :478.45Rubitecan
CAS :<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Formule :C20H15N3O6Degré de pureté :97.54%Couleur et forme :Yellow Amorphous PowderMasse moléculaire :393.35Prulifloxacin
CAS :<p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>Formule :C21H20FN3O6SDegré de pureté :99.47%Couleur et forme :Yellow Or Slightly Yellow PowerMasse moléculaire :461.46Ceralasertib
CAS :<p>Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.</p>Formule :C20H24N6O2SDegré de pureté :98% - 99.99%Couleur et forme :SolidMasse moléculaire :412.51VE-821
CAS :<p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>Formule :C18H16N4O3SDegré de pureté :97.19% - 99.97%Couleur et forme :SolidMasse moléculaire :368.41Cycloastragenol
CAS :<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Formule :C30H50O5Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :490.71γ-Oryzanol
CAS :<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formule :C40H58O4Degré de pureté :mixture - mixtureCouleur et forme :White Or White Crystalline Powder OdourlessMasse moléculaire :602.9Thiomyristoyl
CAS :<p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>Formule :C34H51N3O3SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :581.85MN-64
CAS :<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Formule :C18H16O2Degré de pureté :99.5% - 99.93%Couleur et forme :SolidMasse moléculaire :264.32Pixantrone
CAS :<p>Pixantrone has anti-tumor activity that is a DNA intercalator and topoisomerase II inhibitor.</p>Formule :C17H19N5O2Couleur et forme :SolidMasse moléculaire :325.37BMH-21
CAS :<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Formule :C21H20N4O2Degré de pureté :99.47% - 99.84%Couleur et forme :SolidMasse moléculaire :360.41
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