Altération de l'ADN/réparation de l'ADN
Les inhibiteurs de la réparation des dommages à l'ADN sont des composés qui interfèrent avec les processus impliqués dans la détection et la réparation des dommages à l'ADN. Ces inhibiteurs sont essentiels pour étudier les mécanismes de la stabilité génomique, de la mutagenèse et de la réponse aux dommages à l'ADN. Ils sont également importants dans la recherche sur le cancer, car de nombreuses tumeurs dépendent de voies spécifiques de réparation de l'ADN pour survivre. En inhibant ces voies, les inhibiteurs de la réparation des dommages à l'ADN peuvent améliorer l'efficacité de la chimiothérapie et de la radiothérapie. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité de la réparation des dommages à l'ADN pour soutenir vos recherches en biologie moléculaire, oncologie et pharmacologie.
Sous-catégories appartenant à la catégorie "Altération de l'ADN/réparation de l'ADN"
- ATM/ATR(71 produits)
- Alkylation de l'ADN(11 produits)
- Méthyltransférase de l’ADN(421 produits)
- Gyrase de l’ADN(11 produits)
- ADN-PK(51 produits)
- MTH1(1 produits)
- Antimétabolite nucléosidique/analogue(1.388 produits)
- Transcriptase inverse(43 produits)
- Sirtuine(88 produits)
- Télomérase(33 produits)
- Topoisomérase(136 produits)
Affichez 3 plus de sous-catégories
957 produits trouvés pour "Altération de l'ADN/réparation de l'ADN"
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Adenine hydrochloride
CAS :<p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>Formule :C5H5N5·HClDegré de pureté :98.86%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :171.59ITSA-1
CAS :<p>ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.</p>Formule :C13H7Cl2N3ODegré de pureté :99.78% - 99.89%Couleur et forme :SolidMasse moléculaire :292.12SirReal2
CAS :<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Formule :C22H20N4OS2Degré de pureté :98.96% - 99.75%Couleur et forme :SolidMasse moléculaire :420.55GSK3685032
CAS :<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formule :C22H24N6OSDegré de pureté :98.56% - 99.49%Couleur et forme :SolidMasse moléculaire :420.53NU 7026
CAS :<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Formule :C17H15NO3Degré de pureté :99.51% - >99.99%Couleur et forme :SolidMasse moléculaire :281.31Hinokitiol
CAS :<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Formule :C10H12O2Degré de pureté :99.49% - 99.67%Couleur et forme :SolidMasse moléculaire :164.2Carmustine
CAS :<p>Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.</p>Formule :C5H9Cl2N3O2Degré de pureté :98% - 99.91%Couleur et forme :Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)Masse moléculaire :214.05VAL-083
CAS :<p>VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.</p>Formule :C6H10O4Degré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :146.14PI3K-IN-1
CAS :<p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>Formule :C31H29N5O6SDegré de pureté :97.03% - 98%Couleur et forme :SolidMasse moléculaire :599.66Niraparib
CAS :<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39FIT-039
CAS :<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Formule :C17H18FN3SDegré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :315.41BRD7116
CAS :<p>BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.</p>Formule :C28H36N2O4SDegré de pureté :99.69% - 99.91%Couleur et forme :SolidMasse moléculaire :496.66Adenine hemisulfate
CAS :<p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>Formule :(C5H5N5)·H2SO4Degré de pureté :99.48%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :368.33BIBR 1532
CAS :<p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>Formule :C21H17NO3Degré de pureté :98.49% - 98.90%Couleur et forme :SolidMasse moléculaire :331.364-amino-1,8-Naphthalimide
CAS :<p>4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM</p>Formule :C12H8N2O2Degré de pureté :95.13%Couleur et forme :Yellow Solid PowderMasse moléculaire :212.2NMS-P118
CAS :<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Formule :C20H24F3N3O2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :395.42CP-466722
CAS :<p>CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.</p>Formule :C17H15N7O2Degré de pureté :99.1% - 99.14%Couleur et forme :SolidMasse moléculaire :349.35CAY10603
CAS :<p>CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.</p>Formule :C22H30N4O6Degré de pureté :95.75% - 98.1%Couleur et forme :SolidMasse moléculaire :446.5RK-287107
CAS :<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Formule :C22H26F2N4O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :416.46Thiacloprid
CAS :<p>Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.</p>Formule :C10H9ClN4SDegré de pureté :98.66% - 99.95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :252.72Ciprofloxacin hydrochloride monohydrate
CAS :<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Formule :C17H21ClFN3O4Degré de pureté :99.23% - 99.85%Couleur et forme :White Or Yellowish Crystalline PowderMasse moléculaire :385.82Pentamidine dihydrochloride
CAS :<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Formule :C19H26Cl2N4O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :413.34Silver sulfadiazine
CAS :<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formule :C10H9AgN4O2SDegré de pureté :99.04% - 99.58%Couleur et forme :SolidMasse moléculaire :357.14BCH001
CAS :<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Formule :C20H15F3N2O5Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :420.34NU2058
CAS :<p>NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.</p>Formule :C12H17N5ODegré de pureté :99.34% - 99.92%Couleur et forme :SolidMasse moléculaire :247.3Pentamidine isethionate
CAS :<p>Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent.</p>Formule :C23H36N4O10S2Degré de pureté :98% - 99.83%Couleur et forme :Slight Butyric Odor Very Bitter Taste Ph (5% Aqueous Solution) 4 5-6 5 (Ntp 1992)Masse moléculaire :592.68Trifluridine/tipiracil hydrochloride mixture
CAS :<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Formule :C29H34Cl2F6N8O12Degré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :871.53Remodelin hydrobromide
CAS :<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Formule :C15H15BrN4SDegré de pureté :97.22% - 99.84%Couleur et forme :SolidMasse moléculaire :363.275Rucaparib Phosphate
CAS :<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Formule :C19H18FN3O·H3PO4Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :421.36Trovafloxacin
CAS :<p>Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.</p>Formule :C20H15F3N4O3Degré de pureté :99.21% - 99.27%Couleur et forme :SolidMasse moléculaire :416.35Dxd
CAS :<p>Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM). Dxd was used as a conjugate drug for HER2-targeted ADCs. High-Quality, Low-Cost!</p>Formule :C26H24FN3O6Degré de pureté :98.21% - ≥98%Couleur et forme :SolidMasse moléculaire :493.48Bendamustine
CAS :<p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>Formule :C16H21Cl2N3O2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :358.26Clomesone
CAS :<p>Clomesone, a synthetic drug, treats female infertility by blocking brain estrogen, inducing ovulation.</p>Formule :C4H9ClO5S2Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :236.69AZ20
CAS :<p>AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.</p>Formule :C21H24N4O3SDegré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :412.51Topovale
CAS :<p>Topovale (ARC111) is a potent inhibitor of topoisomerase I.</p>Formule :C23H23N3O5Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :421.45NU6027
CAS :<p>NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-</p>Formule :C11H17N5O2Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :251.29ME0328
CAS :<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Formule :C19H19N3O2Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :321.37Razoxane
CAS :<p>Razoxane is used as an antimitotic agent with immunosuppressive properties.</p>Formule :C11H16N4O4Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :268.27KU60019
CAS :<p>Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.</p>Formule :C30H33N3O5SDegré de pureté :95.9% - 99.36%Couleur et forme :SolidMasse moléculaire :547.67TH34
CAS :<p>TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.</p>Formule :C15H16N2O2Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :256.3KCC-07
CAS :<p>KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.</p>Formule :C14H11N3OSDegré de pureté :98.86% - 99.01%Couleur et forme :SolidMasse moléculaire :269.32Triazavirin
CAS :<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Formule :C5H7N6NaO5SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :286.2Tasquinimod
CAS :<p>Tasquinimod (ABR-215050) is an oral antiangiogenic agent and S100A9 inhibitor that binds to the HDAC4Zn2+ binding structural domain with Kd values ranging from 10 to 30 nM.Cost-effective and quality-assured.</p>Formule :C20H17F3N2O4Degré de pureté :99.22% - >99.99%Couleur et forme :SolidMasse moléculaire :406.36T0070907
CAS :<p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.</p>Formule :C12H8ClN3O3Degré de pureté :98.25% - 99.98%Couleur et forme :SolidMasse moléculaire :277.66UBCS039
CAS :<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Formule :C16H13N3Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :247.29PI-3065
CAS :<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Formule :C27H31FN6OSDegré de pureté :99.84% - ≥95%Couleur et forme :SolidMasse moléculaire :506.64SRT 1720
CAS :<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Formule :C25H23N7OSDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :469.56GW9662
CAS :<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Formule :C13H9ClN2O3Degré de pureté :98% - 99.95%Couleur et forme :Off-White SolidMasse moléculaire :276.681,4-Naphthoquinone
CAS :<p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>Formule :C10H6O2Degré de pureté :99.24% - 99.56%Couleur et forme :SolidMasse moléculaire :158.151-Hydroxyanthraquinone
CAS :<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Formule :C14H8O3Degré de pureté :99.56%Couleur et forme :Orange Red Needles Red-Orange To Fine Yellow CrystalsMasse moléculaire :224.21Rubitecan
CAS :<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Formule :C20H15N3O6Degré de pureté :97.54%Couleur et forme :Yellow Amorphous PowderMasse moléculaire :393.35AG14361
CAS :<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Formule :C19H20N4ODegré de pureté :98.7% - 99.93%Couleur et forme :SolidMasse moléculaire :320.39Gatifloxacin hydrochloride
CAS :<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Formule :C19H23ClFN3O4Degré de pureté :99.85% - 99.89%Couleur et forme :SolidMasse moléculaire :411.86EIDD-1931
CAS :<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Formule :C9H13N3O6Degré de pureté :99.14% - 99.73%Couleur et forme :SolidMasse moléculaire :259.22CXD101
CAS :<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Formule :C24H29N5ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :403.521-Oleoyl lysophosphatidic acid sodium
CAS :<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Formule :C21H40O7P·NaDegré de pureté :98.75% - 99.24%Couleur et forme :SolidMasse moléculaire :458.51MK-4827 Racemate
CAS :<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Formule :C19H20N4ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :320.39Cycloastragenol
CAS :<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Formule :C30H50O5Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :490.71GNE-3511
CAS :<p>GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.</p>Formule :C23H26F2N6ODegré de pureté :98.3% - 99.51%Couleur et forme :SolidMasse moléculaire :440.49PIK-93
CAS :<p>PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.</p>Formule :C14H16ClN3O4S2Degré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :389.889-Hydroxycamptothecin
CAS :<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Formule :C20H16N2O5Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :364.35Xanthosine 5'-monophosphate sodium salt
CAS :<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Formule :C10H11N4Na2O9PDegré de pureté :99% - 99.77%Couleur et forme :SolidMasse moléculaire :408.17Deoxycytidine triphosphate
CAS :<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Formule :C9H16N3O13P3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :467.16NKL 22
CAS :<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Formule :C19H23N3O2Degré de pureté :96.16% - 96.24%Couleur et forme :SolidMasse moléculaire :325.4AGK7
CAS :<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Formule :C23H13Cl2N3O2Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :434.27MN-64
CAS :<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Formule :C18H16O2Degré de pureté :99.5% - 99.93%Couleur et forme :SolidMasse moléculaire :264.32E7449
CAS :<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Formule :C18H15N5ODegré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :317.34Methotrexate disodium
CAS :<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formule :C20H20N8Na2O5Degré de pureté :99.77% - 99.96%Couleur et forme :SolidMasse moléculaire :498.4AZD-7648
CAS :<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Formule :C18H20N8O2Degré de pureté :99.03% - 99.85%Couleur et forme :SolidMasse moléculaire :380.4AZ6102
CAS :<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Formule :C25H28N6ODegré de pureté :97.98% - 99.91%Couleur et forme :SolidMasse moléculaire :428.53OUL35
CAS :<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Formule :C14H12N2O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :256.26AG-494
CAS :<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Formule :C16H12N2O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :280.28Clofibrate
CAS :<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Formule :C12H15ClO3Degré de pureté :98.77%Couleur et forme :Oil LiquidMasse moléculaire :242.70Selisistat S-enantiomer
CAS :<p>Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.</p>Formule :C13H13ClN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :248.71Suramin Sodium Salt
CAS :<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Formule :C51H34N6Na6O23S6Degré de pureté :97.47% - 99.97%Couleur et forme :WhiteMasse moléculaire :1429.15Citarinostat
CAS :<p>ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.</p>Formule :C24H26ClN5O3Degré de pureté :98.06% - 99.06%Couleur et forme :SolidMasse moléculaire :467.95Pamiparib
CAS :<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Formule :C16H15FN4ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :298.31Fluzoparib
CAS :<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Formule :C22H16F4N6O2Degré de pureté :98.53% - 99.63%Couleur et forme :SolidMasse moléculaire :472.4Bisantrene
CAS :<p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>Formule :C22H22N8Degré de pureté :96.07% - 98.57%Couleur et forme :SolidMasse moléculaire :398.46DMNB
CAS :<p>DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor, an enzyme involved in the NHEJ pathway of DSB repair in human cells.</p>Formule :C9H9NO5Degré de pureté :97.87%Couleur et forme :Yellow SolidMasse moléculaire :211.17Bobcat339
CAS :<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Formule :C16H12ClN3ODegré de pureté :97.79% - 99.24%Couleur et forme :SolidMasse moléculaire :297.74CGK733
CAS :<p>CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.</p>Formule :C23H18Cl3FN4O3SDegré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :555.84AZD 6482
CAS :<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formule :C22H24N4O4Degré de pureté :99.79% - 99.95%Couleur et forme :SolidMasse moléculaire :408.452-Aminopurine
CAS :<p>2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.</p>Formule :C5H5N5Degré de pureté :99.51%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :135.13Compound 401
CAS :<p>Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.</p>Formule :C16H15N3O2Degré de pureté :99.73% - 99.78%Couleur et forme :SolidMasse moléculaire :281.31Selisistat R-enantiomer
CAS :<p>Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).</p>Formule :C13H13ClN2ODegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :248.71G007-LK
CAS :<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formule :C25H16ClN7O3SDegré de pureté :97.63% - 98.17%Couleur et forme :SolidMasse moléculaire :529.96Trabectedin
CAS :<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Formule :C39H43N3O11SDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :761.84Niraparib tosylate monohyrate
CAS :<p>Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.</p>Formule :C26H30N4O5SDegré de pureté :97.7% - 98.41%Couleur et forme :SolidMasse moléculaire :510.61Isosteviol
CAS :<p>Isosteviol is a natural sweetener with anti-inflammatory, anti-tumor, glucose-lowering, and other health benefits.</p>Formule :C20H30O3Degré de pureté :99.72% - 99.97%Couleur et forme :SolidMasse moléculaire :318.45SW044248
CAS :<p>SW044248 is a noncanonical Top1 inhibitor. It has selective toxicity for NSCLC cells.</p>Formule :C22H23N5O2SDegré de pureté :99.56% - 99.87%Couleur et forme :SolidMasse moléculaire :421.52CM-272
CAS :<p>CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.</p>Formule :C28H38N4O3Degré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :478.63LY294002
CAS :<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formule :C19H17NO3Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow SolidMasse moléculaire :307.34Torin 2
CAS :<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Formule :C24H15F3N4ODegré de pureté :98.31% - 99.32%Couleur et forme :SolidMasse moléculaire :432.4Cardioxane
CAS :<p>Cardioxane (ADR-529) is a cardio-protective drug.</p>Formule :C11H16N4O4·HClDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :304.73Adefovir
CAS :<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Formule :C8H12N5O4PDegré de pureté :99.56%Couleur et forme :White To Off-White PowderMasse moléculaire :273.19PJ34 hydrochloride
CAS :<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formule :C17H18ClN3O2Degré de pureté :98.87% - ≥95%Couleur et forme :SolidMasse moléculaire :331.8SRT 2104
CAS :<p>SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.</p>Formule :C26H24N6O2S2Degré de pureté :98.34% - 99.82%Couleur et forme :SolidMasse moléculaire :516.64Leniolisib
CAS :<p>Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).</p>Formule :C21H25F3N6O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :450.46Palifosfamide
CAS :<p>Palifosfamide lysine (ZIO-201) stable, effective vs. sarcomas in vitro. IC50: 2.25-6.75 μM, except OS222 at 31.5 μM.</p>Formule :C4H11Cl2N2O2PDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :221.02360A
CAS :<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formule :C27H23N5O2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.5Lomeguatrib
CAS :<p>Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .</p>Formule :C10H8BrN5OSDegré de pureté :99.26% - >99.99%Couleur et forme :SolidMasse moléculaire :326.17Nexturastat A
CAS :<p>Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is >190-fold than other HDACs.</p>Formule :C19H23N3O3Degré de pureté :99.40% - 99.57%Couleur et forme :SolidMasse moléculaire :341.4ETP-45658
CAS :<p>ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).</p>Formule :C16H17N5O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :311.34Dactolisib
CAS :<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formule :C30H23N5ODegré de pureté :97.64% - 99.85%Couleur et forme :SolidMasse moléculaire :469.54Pimelic diphenylamide 106
CAS :<p>Pimelic diphenylamide 106 (RGFA-8) is a slow, tight-binding inhibitor of class I HDAC, showing no activity against class II HDACs.</p>Formule :C20H25N3O2Degré de pureté :95.25% - 99.28%Couleur et forme :SolidMasse moléculaire :339.43TMP269
CAS :<p>TMP269: Class IIa HDAC inhibitor; HDAC4 IC50=157 nM, HDAC5 IC50=97 nM, HDAC7 IC50=43 nM, HDAC9 IC50=23 nM.</p>Formule :C25H21F3N4O3SDegré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :514.52Amonafide
CAS :<p>Amonafide (NSC-308847, AS1413) causes DNA breaks via topoisomerase II, not topoisomerase I.</p>Formule :C16H17N3O2Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :283.33A-966492
CAS :<p>A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.</p>Formule :C18H17FN4ODegré de pureté :98.53% - 99.27%Couleur et forme :SolidMasse moléculaire :324.356-AZATHYMINE
CAS :<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Formule :C4H5N3O2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :127.1ACY-775
CAS :<p>ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).</p>Formule :C17H19FN4O2Degré de pureté :97.67% - 98.83%Couleur et forme :SolidMasse moléculaire :330.36Satraplatin
CAS :<p>Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical</p>Formule :C10H22Cl2N2O4PtDegré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :500.28CRT0044876
CAS :<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Formule :C9H6N2O4Degré de pureté :98.27% - 98.98%Couleur et forme :Brown PowderMasse moléculaire :206.15azd1390
CAS :<p>AZD1390: Potent ATM inhibitor (IC50: 0.78 nM), >10,000-fold selectivity vs. PIKK enzymes.</p>Formule :C27H32FN5O2Degré de pureté :97.41% - 99.72%Couleur et forme :SolidMasse moléculaire :477.57RGFP966
CAS :<p>RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.</p>Formule :C21H19FN4ODegré de pureté :99.2% - 99.88%Couleur et forme :SolidMasse moléculaire :362.4RG2833
CAS :<p>RG2833 (RGFP109) (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.</p>Formule :C20H25N3O2Degré de pureté :99% - 99.50%Couleur et forme :SolidMasse moléculaire :339.433,4-Dicaffeoylquinic acid
CAS :<p>3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.</p>Formule :C25H24O12Degré de pureté :96.33% - 98.82%Couleur et forme :SolidMasse moléculaire :516.45Seclidemstat
CAS :<p>Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.</p>Formule :C20H23ClN4O4SDegré de pureté :98.28% - 99.76%Couleur et forme :SolidMasse moléculaire :450.94Veliparib dihydrochloride
CAS :<p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>Formule :C13H18Cl2N4ODegré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :317.21Prexasertib dihydrochloride
CAS :<p>Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.</p>Formule :C18H21Cl2N7O2Degré de pureté :98.46% - 99.82%Couleur et forme :SolidMasse moléculaire :438.316-Thioguanine
CAS :<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Formule :C5H5N5SDegré de pureté :98.34% - >99.99%Couleur et forme :Odorless Or Almost Odorless Pale Yellow Crystalline PowderMasse moléculaire :167.19SIS17
CAS :<p>SIS17: Potent, selective HDAC11 inhibitor (IC50: 0.83 μM), blocks serine hydroxymethyl transferase 2 demyristoylation, spares other HDACs.</p>Formule :C21H38N2OSDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :366.6CC-115
CAS :<p>CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).</p>Formule :C16H16N8ODegré de pureté :86.79% - 99.01%Couleur et forme :SolidMasse moléculaire :336.35SRT 1460
CAS :<p>SRT 1460 is a SIRT1 activator.</p>Formule :C26H29N5O4SDegré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :507.6Venadaparib
CAS :<p>Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.</p>Formule :C23H23FN4O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :406.45Ochromycinone
CAS :<p>Ochromycinone (STA 21) is a selective STAT3 inhibitor.</p>Formule :C19H14O4Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :306.315-Methyl-2'-deoxycytidine
CAS :<p>5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.</p>Formule :C10H15N3O4Degré de pureté :99.18% - 99.69%Couleur et forme :SolidMasse moléculaire :241.245-Fluoro-2'-deoxycytidine
CAS :<p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>Formule :C9H12FN3O4Degré de pureté :97.91%Couleur et forme :Fine White PowderMasse moléculaire :245.21Bimolane
CAS :<p>Bimolane is a topoisomerase II inhibitor.</p>Formule :C20H32N6O6Degré de pureté :99.13% - 99.29%Couleur et forme :SolidMasse moléculaire :452.5Amsacrine hydrochloride
CAS :<p>Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.</p>Formule :C21H20ClN3O3SDegré de pureté :99.05% - 99.92%Couleur et forme :SolidMasse moléculaire :429.92Levofloxacin
CAS :<p>Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.</p>Formule :C18H20FN3O4Degré de pureté :98.14% - 99.80%Couleur et forme :Off-White To Yellow CrystalsMasse moléculaire :361.37ACY-738
CAS :<p>ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.</p>Formule :C14H14N4O2Degré de pureté :98.85% - 99.89%Couleur et forme :SolidMasse moléculaire :270.29YU238259
CAS :<p>YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.</p>Formule :C22H22ClN3O4SDegré de pureté :99.28% - 99.56%Couleur et forme :SolidMasse moléculaire :459.95GeA-69
CAS :<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Formule :C20H16N2ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :300.35Talazoparib
CAS :<p>Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).</p>Formule :C19H14F2N6ODegré de pureté :97.02% - 99.92%Couleur et forme :SolidMasse moléculaire :380.35Tunicamycin
CAS :<p>Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT).</p>Formule :C39H64N4O16Degré de pureté :98.77%Couleur et forme :White Crystalline SolidMasse moléculaire :844.94 (n=10)LY-294002 hydrochloride
CAS :<p>LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.</p>Formule :C19H17NO3·HClDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :343.81HDAC8-IN-1
CAS :<p>MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines.</p>Formule :C22H19NO3Degré de pureté :97.13% - 99.19%Couleur et forme :SolidMasse moléculaire :345.39Belinostat
CAS :<p>Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.</p>Formule :C15H14N2O4SDegré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :318.35Veliparib
CAS :<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Formule :C13H16N4ODegré de pureté :98.66% - 99%Couleur et forme :SolidMasse moléculaire :244.29SF2523
CAS :<p>SF2523 is a highly selective and potent inhibitor.</p>Formule :C19H17NO5SDegré de pureté :99.1% - 99.51%Couleur et forme :SolidMasse moléculaire :371.41SGI-1027
CAS :<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.523-Methoxybenzamide
CAS :<p>3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.</p>Formule :C8H9NO2Degré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :151.16HDAC-IN-7
CAS :<p>HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide.</p>Formule :C22H19FN4O2Degré de pureté :97.64% - 98.45%Couleur et forme :SolidMasse moléculaire :390.41Pirarubicin
CAS :<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formule :C32H37NO12Degré de pureté :97.80% - 99.15%Couleur et forme :Red Crystalline PowderMasse moléculaire :627.64Potassium acetate
CAS :<p>Potassium acetate (Diuretic salt) with antibacterial and antifungal properties.</p>Formule :C2H3KO2Degré de pureté :≥98%Couleur et forme :Colorless Lustrous Rapidly Deliquescent Crystals Or White Crystal Powder Or Flakes Solid Repidly Deliquescent Crystals Or White Crystal Powder Or FlakesMasse moléculaire :98.14TAS-103 dihydrochloride
CAS :<p>TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.</p>Formule :C20H21Cl2N3O2Degré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :406.31KU-0060648
CAS :<p>KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ.</p>Formule :C33H34N4O4SDegré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :582.71Hypericin
CAS :<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Formule :C30H16O8Degré de pureté :99.05% - ≥98%Couleur et forme :Red-Coloured Anthraquinone-DerivativeMasse moléculaire :504.44PIK-75
CAS :<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Formule :C16H14BrN5O4SDegré de pureté :98.52% - >99.99%Couleur et forme :SolidMasse moléculaire :452.28RG108
CAS :<p>RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).</p>Formule :C19H14N2O4Degré de pureté :98% - 99.43%Couleur et forme :SolidMasse moléculaire :334.33ETP-46464
CAS :<p>ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).</p>Formule :C30H22N4O2Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :470.52Brincidofovir
CAS :<p>Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir.</p>Formule :C27H52N3O7PDegré de pureté :98% - 99.62%Couleur et forme :SolidMasse moléculaire :561.69Neobavaisoflavone
CAS :<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Formule :C20H18O4Degré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :322.35RGFP966 (E-isomer)
CAS :<p>RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.</p>Formule :C21H19FN4ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :362.4MDL-800
CAS :<p>MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.</p>Formule :C21H16BrCl2FN2O6S2Degré de pureté :99.95% - 99.96%Couleur et forme :SolidMasse moléculaire :626.3Semustine
CAS :<p>Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for</p>Formule :C10H18ClN3O2Degré de pureté :99.70%Couleur et forme :Light Yellow PowderMasse moléculaire :247.72Talazoparib tosylate
CAS :<p>PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.</p>Formule :C26H22F2N6O4SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :552.55Mouse PARP2(Poly [ADP-ribose] polymerase 2) ELISA Kit
<p>The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PARP2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PARP2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PARP2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PARP2 in the samples is then determined by comparing the OD of the samples to the standard curve.</p>Couleur et forme :Colourless TransparentliquidCHDI-390576
CAS :<p>CHDI-390576 is an HDAC inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, and HDAC 9, and can be used in cancer research.</p>Formule :C19H13F4N3O2Degré de pureté :98.92% - 99.03%Couleur et forme :SolidMasse moléculaire :391.32IndiMitecan
CAS :<p>IndiMitecan (LMP776) is an inhibitor of topoisomerase I (Top1) with anticancer activities [1].</p>Formule :C25H21N3O6Degré de pureté :98.53%Couleur et forme :SoildMasse moléculaire :459.45Exatecan
CAS :<p>Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL).Exatecan has antitumor activity and may be used in</p>Formule :C24H22FN3O4Degré de pureté :99.64% - 99.84%Couleur et forme :SolidMasse moléculaire :435.45CBHcy
CAS :<p>CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.</p>Formule :C9H17NO4SDegré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :235.3Mirin
CAS :<p>Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor and also inhibits Mre11-associated exonuclease activity.Mirin induces cell cycle arrest in G1 phase.</p>Formule :C10H8N2O2SDegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :220.25Cyclophosphamide-d4
CAS :<p>Cyclophosphamide-d4 is a deuterated compound of Cyclophosphamide. Cyclophosphamide has a CAS number of 50-18-0. Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.</p>Formule :C7H11D4Cl2N2O2PCouleur et forme :SolidMasse moléculaire :265.11BRD 4354 ditrifluoroacetate
<p>BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).</p>Formule :C25H25ClF6N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :610.93ART0380
CAS :<p>ART0380 is a potent, antitumor, selective, orally available, ATP-competitive ATR kinase inhibitor for the study of ataxia telangiectasia mutated (ATM) cancer.</p>Formule :C18H24N6O2SDegré de pureté :99.06% - >99.99%Couleur et forme :SolidMasse moléculaire :388.49PNU-159682
CAS :<p>PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin.</p>Formule :C32H35NO13Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :641.62MY-1B
CAS :<p>MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.</p>Formule :C22H18BrN3O2Degré de pureté :99.81% - >99.99%Couleur et forme :SoildMasse moléculaire :436.37-Methyladenine
CAS :<p>7-Methyladenine (NSC-7857) can be used as a marker of exposure to exogenous and carcinogenic methylating agents.</p>Formule :C6H7N5Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :149.15LMP744
CAS :<p>LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.</p>Formule :C24H24N2O7Couleur et forme :SolidMasse moléculaire :452.46A-1062
CAS :<p>A-1062, a resolvase-binding inhibitor, inhibits resolvase binding to the res site.</p>Formule :C18H10O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.33Lobeglitazone Sulfate
CAS :<p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>Formule :C24H26N4O9S2Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :578.61BVT.13
CAS :<p>BVT.13 is used as a selective PPAR-gamma activator.</p>Formule :C18H11Cl2N3O4Couleur et forme :SolidMasse moléculaire :404.2Guadecitabine
CAS :<p>Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.</p>Formule :C18H24N9O10PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :557.41BRD0539
CAS :<p>BRD0539 is a cell-permeable spCas9 inhibitor that blocks the binding of spCas9 to DNA and inhibits Streptococcus pyogenes Cas9 (SpCas9).</p>Formule :C25H25FN2O3SDegré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :452.54Naveglitazar racemate
CAS :<p>Naveglitazar racemate is the racemate of Naveglitazar.</p>Formule :C25H26O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :422.47Chlornaphazine
CAS :<p>Chlornaphazine is an antineoplastic and has been identified as a human carcinogen.</p>Formule :C14H15Cl2NDegré de pureté :98%Couleur et forme :Less Plates Or Brown Solid (Ntp 1992) Physical Description Colorless Plates Or Brown Solid (Ntp 1992)Masse moléculaire :268.18Arazine
CAS :<p>Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.</p>Formule :C20H33NO3SDegré de pureté :90%Couleur et forme :SolidMasse moléculaire :367.55NU/ICRF 500
CAS :<p>NU/ICRF 500 is a novel anthracenyl-amino acid catalytic inhibitor of topoisomerase II.</p>Formule :C17H15N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.32S-Aristeromycinylhomocysteine
CAS :<p>S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.</p>Formule :C15H22N6O4SCouleur et forme :SolidMasse moléculaire :382.44GW0072
CAS :<p>GW0072 is a partial agonist of PPARγ.</p>Formule :C36H44N2O4SCouleur et forme :SolidMasse moléculaire :600.812′-Deoxy-5-nitrocytidine
CAS :<p>2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].</p>Formule :C9H12N4O6Couleur et forme :SolidMasse moléculaire :272.21KDT 501 potassium
CAS :<p>KDT 501, a PPAR agonist and G protein-coupled receptor (GPR) 120 agonist, is used potentially for the treatment of type 2 diabetes.</p>Formule :C21H34KO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.596GSK-7227
CAS :<p>GSK-7227 is a novel PPARδ partial agonist that upregulates target genes in muscle cells, indicating its potential role in modulating muscle metabolism and energy.</p>Formule :C25H22N2O6SDegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :478.52L-764406
CAS :<p>L-764406 is a partial agonist of human PPAR gamma.</p>Formule :C15H11ClN2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :318.78A 9387
CAS :<p>A 9387 is an inhibitor of resolvase protein.</p>Formule :C12H6Br2Cl2O2SCouleur et forme :SolidMasse moléculaire :444.95CAY10767
CAS :<p>CAY10767 is a PPARα agonist with an EC50 of 37 nM; over 2700x selective against PPARγ/δ.</p>Formule :C22H20FNO3Couleur et forme :SolidMasse moléculaire :365.4Hepsulfam
CAS :<p>Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).</p>Formule :C7H18N2O6S2Couleur et forme :SolidMasse moléculaire :290.36C-333H
CAS :<p>C-333H is a new PPARalpha/gamma dual agonist.</p>Formule :C28H26N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.52DC_501
CAS :<p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>Formule :C25H23Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.38(S)-Gyramide A
CAS :<p>(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division.</p>Formule :C21H27FN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.51Lexitropsin
CAS :<p>Lexitropsin is a novel anticancer drug.</p>Formule :C20H29N5O4Couleur et forme :SolidMasse moléculaire :403.48NU-7163
CAS :<p>NU-7163 is a potent and selective inhibitor of ATP-competitive DNA-PK.</p>Formule :C18H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.33Romazarit
CAS :<p>Romazarit, a propionic acid derivative, is used as a PPARα agonist and acts as an antirheumatic drug.</p>Formule :C15H16ClNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :309.74LY-510929
CAS :<p>LY-510929: PPAR agonist for hyperlipidemia, metabolic issues, type 2 diabetes.</p>Formule :C26H25NO5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.55Elaidyl-sulfamide
CAS :<p>Elaidyl-sulfamide is a sulfamoyl analogue of oleoylethanolamide (OEA). ES is a lipid mediator of satiety that acts through the PPARα.</p>Formule :C18H38N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :346.57A 20832
CAS :<p>A-20832 blocks strand cleavage in resolvase-driven recombination; doesn't prevent resolvase-res binding or synapse formation, only binds at res site I.</p>Formule :C10H14Cl2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :253.12Leurubicin
CAS :<p>Leurubicin is used as a prodrug of doxorubicin.</p>Formule :C33H40N2O12Degré de pureté :98.66% - >99.99%Couleur et forme :SolidMasse moléculaire :656.68NC182
CAS :<p>NC182 is a topo II inhibitor that shows selective and potent topo II inhibition on the induction of topo II-dependent DNA fragmentation.</p>Formule :C24H24N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.47
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