Antimétabolite nucléosidique/analogue
Les antimétabolites et analogues des nucléosides sont des composés qui imitent les nucléosides naturels et sont incorporés dans l'ADN lors de la réplication, entraînant la terminaison de la chaîne ou l'inhibition de la synthèse de l'ADN. Ces composés sont largement utilisés comme agents chimiothérapeutiques dans le traitement du cancer et des infections virales. En perturbant la synthèse de l'ADN, les analogues des nucléosides induisent l'arrêt du cycle cellulaire et l'apoptose. Chez CymitQuimica, nous offrons une large gamme d'antimétabolites et d'analogues de nucléosides de haute qualité pour soutenir vos recherches sur le traitement du cancer, la thérapie antivirale et la réplication de l'ADN.
386 produits trouvés pour "Antimétabolite nucléosidique/analogue".
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Doxifluridine
CAS :Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.Formule :C9H11FN2O5Degré de pureté :99.47% - 99.86%Couleur et forme :SolidMasse moléculaire :246.19Stavudine
CAS :Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.Formule :C10H12N2O4Degré de pureté :99.01% - 99.88%Couleur et forme :White SolidMasse moléculaire :224.21Gemcitabine
CAS :Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4Degré de pureté :98.66% - 99.67%Couleur et forme :SolidMasse moléculaire :263.20Adenosine
CAS :Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.Formule :C10H13N5O4Degré de pureté :98.76% - 99.86%Couleur et forme :Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)Masse moléculaire :267.24Trifluridine
CAS :Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.Formule :C10H11F3N2O5Degré de pureté :99.39% - 99.82%Couleur et forme :White Crystalline PowderMasse moléculaire :296.25-Azacytidine
CAS :5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formule :C8H12N4O5Degré de pureté :99.31% - 99.87%Couleur et forme :White SolidMasse moléculaire :244.2Clofarabine
CAS :Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotideFormule :C10H11ClFN5O3Degré de pureté :99.94% - >99.99%Couleur et forme :SolidMasse moléculaire :303.68Fludarabine
CAS :Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Formule :C10H12FN5O4Degré de pureté :99.65% - 99.89%Couleur et forme :White SolidMasse moléculaire :285.23Vidarabine
CAS :Vidarabine is a nucleoside antibiotic from Streptomyces with antiviral properties, effective against herpes and other DNA viruses.Formule :C10H13N5O4Degré de pureté :99.85% - 99.91%Couleur et forme :White SolidMasse moléculaire :267.24Decitabine
CAS :Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.Formule :C8H12N4O4Degré de pureté :98.06% - 99.87%Couleur et forme :SolidMasse moléculaire :228.21Orotic acid
CAS :Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.Formule :C5H4N2O4Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :156.1Cytarabine
CAS :Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formule :C9H13N3O5Degré de pureté :99.83% - 99.93%Couleur et forme :Fine Off-White Crystalline PowderMasse moléculaire :243.22Tegafur
CAS :Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.Formule :C8H9FN2O3Degré de pureté :99.16% - 99.89%Couleur et forme :SolidMasse moléculaire :200.176-Mercaptopurine
CAS :6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.Formule :C5H4N4SDegré de pureté :99.53% - 99.63%Couleur et forme :Yellow Crystalline Powder SolidMasse moléculaire :152.18Carmofur
CAS :Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Formule :C11H16FN3O3Degré de pureté :98.53% - 99.98%Couleur et forme :SolidMasse moléculaire :257.26SIBA
CAS :SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.Formule :C14H21N5O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :339.41Ref: TM-T12908
1mg49,00€5mg88,00€1mL*10mM (DMSO)99,00€10mg111,00€25mg207,00€50mg311,00€100mg444,00€200mg618,00€Floxuridine
CAS :Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Formule :C9H11FN2O5Degré de pureté :98.92% - 99.96%Couleur et forme :SolidMasse moléculaire :246.19Cytidine
CAS :Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond.Formule :C9H13N3O5Degré de pureté :98.80% - 99.63%Couleur et forme :White SolidMasse moléculaire :243.22Ganciclovir
CAS :Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus.Formule :C9H13N5O4Degré de pureté :99.55% - 99.58%Couleur et forme :White SolidMasse moléculaire :255.235-Fluorouracil
CAS :5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis.Formule :C4H3FN2O2Degré de pureté :98% - >99.99%Couleur et forme :White SolidMasse moléculaire :130.08Capecitabine
CAS :Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.Formule :C15H22FN3O6Degré de pureté :99.81% - >99.99%Couleur et forme :White SolidMasse moléculaire :359.35Dacarbazine
CAS :Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.Formule :C6H10N6ODegré de pureté :99.78% - 99.87%Couleur et forme :White SolidMasse moléculaire :182.183'-Deoxy-N1-Methyl inosine
3’-Deoxy-N1-Methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formule :C11H14N4O4Couleur et forme :SolidMasse moléculaire :266.25N1-Methyl-2'-O-(2-methoxyethyl) guanosine
N1-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formule :C14H21N5O6Couleur et forme :SolidMasse moléculaire :355.352-(P-Cyanophenyl methylidene hydrazino) adenosine
2-(P-Cyanophenyl methylidene hydrazino) adenosine: a purine analog with antitumor effects via DNA synthesis inhibition and apoptosis.Formule :C18H18N8O4Couleur et forme :SolidMasse moléculaire :410.395'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite
5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite, a purine nucleoside analog, exhibits extensive antitumor activity specific to indolent lymphoidFormule :C41H52N5O8PCouleur et forme :SolidMasse moléculaire :773.851-(β-D-Xylofuranosyl)-N6-Isopentenyladenine
1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine is an adenosine analog.Formule :C15H21N5O4Couleur et forme :SolidMasse moléculaire :335.368-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.Formule :C10H11ClFN5O3Couleur et forme :SolidMasse moléculaire :303.682-(3-Methyln-propylidene hydrazino) adenosine
2-(3-Methyln-propylidene hydrazino) adenosine: a purine analog with antitumor properties, inhibits DNA synthesis, induces apoptosis.Formule :C15H23N7O4Couleur et forme :SolidMasse moléculaire :365.39(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine
(R)-N-(2,3-Dihydro-1H-indenyl)-2-amino adenosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Formule :C19H22N6O4Couleur et forme :SolidMasse moléculaire :398.423,5'-Bis(O-t-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine
3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine, a cytidine analog, inhibits DNA methyltransferases (e.g., Zebularine), exhibiting potential antiFormule :C23H45N3O5Si2Couleur et forme :SolidMasse moléculaire :499.79N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine
N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoidFormule :C16H16FN3O5Couleur et forme :SolidMasse moléculaire :349.312'-O-Methyladenosine 5'-monophosphate triethyl ammonium
2’-O-Methyladenosine 5’-monophosphate triethyl ammonium is an adenosine analog.Formule :C11H14N5O7P2Couleur et forme :SolidMasse moléculaire :359.236-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits broad antitumor activity byFormule :C15H17N5O6Couleur et forme :SolidMasse moléculaire :363.331-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine
1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenosine analog.Formule :C18H18F3N5O4Couleur et forme :SolidMasse moléculaire :425.36N1-Methyl-2'-O-(2-methoxyethyl) adenosine
N1-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor effects, particularly against indolent lymphoid malignancies.Formule :C14H21N5O5Couleur et forme :SolidMasse moléculaire :339.352'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium
2’-O-Methyl-5-methyluridine 5’-triphosphate (triethylammonium), a thymidine analog, exhibits insertional activity in replicated DNA.Formule :C29H64N5O15P3Couleur et forme :SolidMasse moléculaire :815.76N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H22N2O7Couleur et forme :SolidMasse moléculaire :330.335'-DMTr-3'dA(Bz)-methylphosphonami dite
5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoidFormule :C45H51N6O6PCouleur et forme :SolidMasse moléculaire :802.95'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.Formule :C44H49F2N4O7PCouleur et forme :SolidMasse moléculaire :814.855-Aza-xylo-cytidine
5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Formule :C8H12N4O5Couleur et forme :SolidMasse moléculaire :244.2N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.Formule :C41H43N3O9Couleur et forme :SolidMasse moléculaire :721.79Py-MAA-Val-Cit-PAB-DX8951
CAS :Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].Formule :C57H66FN11O13SCouleur et forme :SolidMasse moléculaire :1164.26N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine
N3-(2S)-propyluridine is a uridine analog with potential as an antiepileptic and for antihypertensive agent research.Formule :C22H35N3O10Couleur et forme :SolidMasse moléculaire :501.53N7-Methyl-2'-O-(2-methoxyethyl) guanosine
N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H21N5O6Couleur et forme :SolidMasse moléculaire :355.35Isocytosine
CAS :Isocytosine ,with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Isocytosine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C4H5N3OCouleur et forme :White To Off-White SolidMasse moléculaire :111.1Rev 2'-O-MOE-5MeC(Bz)-5'-amidite
Rev 2’-O-MOE-5MeC(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C50H60N5O10PCouleur et forme :SolidMasse moléculaire :922.012-Diethoxymethyl adenosine
2-Diethoxymethyl adenosine, an adenosine analog, dilates smooth muscle, inhibits cancer, and leads to drugs like Acadesine.Formule :C23H31N5O10Couleur et forme :SolidMasse moléculaire :537.526-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical andFormule :C10H17N7O3Couleur et forme :SolidMasse moléculaire :283.292'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C21H35FN2O5Couleur et forme :SolidMasse moléculaire :414.51
