Enzyme
Les inhibiteurs d'enzymes sont des molécules qui se lient aux enzymes et diminuent leur activité. Ces inhibiteurs sont largement utilisés en recherche pour étudier la cinétique enzymatique, la régulation et le rôle spécifique des enzymes dans les voies métaboliques. Les inhibiteurs d'enzymes sont également cruciaux dans le développement de médicaments, car de nombreux agents thérapeutiques agissent en inhibant les enzymes impliquées dans les processus pathologiques. En ciblant les enzymes, ces inhibiteurs peuvent moduler les voies biochimiques et offrir des traitements potentiels pour diverses maladies. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs d'enzymes de haute qualité pour soutenir vos recherches en biochimie, pharmacologie et découverte de médicaments.
Sous-catégories appartenant à la catégorie "Enzyme"
- Anhydrase carbonique(196 produits)
- Hydroxylase(36 produits)
- MPO(2 produits)
- Réductase(51 produits)
- Tyrosinase(70 produits)
3618 produits trouvés pour "Enzyme"
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hCAXII-IN-9
hCAXII-IN-9 (Compound 3I) is a selective hCAXII inhibitor with Ki values of 28 nM for hCAXII, 7192.6 nM for hCAI, 188.6 nM for hCAII, and greater than 100000 nM for hCAIX. This compound may be utilized in anti-tumor research.Formule :C24H30N3O7PSMasse moléculaire :535.15421L-Lactate Dehydrogenase from bovine heart, powder, approx. 300 U/mg
CAS :Couleur et forme :Lyophilised powderα-Amylase (with starch)
CAS :Degré de pureté :≥ 600U/gCouleur et forme :White to beige or pale yellow-brown powderhTYR/AbTYR-IN-1
CAS :hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.Formule :C18H20N2O3Degré de pureté :99.73%Couleur et forme :SoildMasse moléculaire :312.36TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Formule :C35H51N3O3Couleur et forme :SolidMasse moléculaire :561.798hCAIX/VII-IN-1
hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX.Formule :C16H13BFN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.1hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formule :C13H10FN3O4Masse moléculaire :291.06553Tyrosinase-IN-15
Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].Degré de pureté :98%Couleur et forme :Odour SolidDorzolamide
CAS :Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.
Formule :C10H16N2O4S3Degré de pureté :98%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :324.44Girentuximab
CAS :Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Couleur et forme :LiquidMasse moléculaire :145.55 kDaCarbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Formule :C17H16N6O3SCouleur et forme :SolidMasse moléculaire :384.41hCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Formule :C19H18N2O3SCouleur et forme :SolidMasse moléculaire :354.42VM4-037
CAS :VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Formule :C26H29FN6O7S2Couleur et forme :SolidMasse moléculaire :620.67CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Couleur et forme :Odour SolidhCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Formule :C24H28N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.58Carbonic anhydrase
CAS :Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.Couleur et forme :SolidIOX2-NH2-1
CAS :IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.Formule :C19H17N3O5Degré de pureté :98.77% - 99.91%Couleur et forme :SoildMasse moléculaire :367.36Carbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Couleur et forme :Odour SolidCAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Formule :C16H13FNO4PCouleur et forme :SolidMasse moléculaire :333.05662hCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Formule :C24H17Cl2N3O3S2Couleur et forme :SolidMasse moléculaire :530.446hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Formule :C23H22N4O7S2Couleur et forme :SolidMasse moléculaire :530.573hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Formule :C22H20N4O6S2Couleur et forme :SolidMasse moléculaire :500.547Chlorothiazide
CAS :Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formule :C7H6ClN3O4S2Degré de pureté :98.46% - 98.91%Couleur et forme :Crystals Physical Description Crystals; White Powder (Ntp 1992)Masse moléculaire :295.72Peroxidase
CAS :Degré de pureté :≥ 85units/mg (dry basis)Couleur et forme :Beige to light-brown, reddish brown or dark brown lyophilised powderMasse moléculaire :-hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5[Asp371]-Tyrosinase (369-377), human
CAS :Tyrosinase (369-377,YMDGTMSQV) originates from tyrosinase and needs TAP and proteosome for cell presentation.Formule :C42H66N10O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1031.16Tyrosinase-IN-26
Tyrosinase-IN-26 (compound 13) is a non-competitive inhibitor of tyrosinase, with an IC50 value of 68.86 µM. It is capable of inhibiting melanin production.Formule :C25H24N2O6Masse moléculaire :448.16344Trypsin, bovine origin
CAS :Degré de pureté :≥ 2000units/mg (USP)Couleur et forme :White or almost white crystalline powderMasse moléculaire :-hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Couleur et forme :Odour SolidhCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Butobendine
CAS :Butobendine is a compound derived from gallic acid and exhibits significant antiarrhythmic activity.Formule :C32H48N2O10Couleur et forme :SolidMasse moléculaire :620.73Diaminopropionoyl tripeptide-33
CAS :Diaminopropionoyl Tripeptide-33 is a bioactive peptide that safeguards skin cells against UVA-induced DNA damage and is utilized as a cosmetic ingredient [1].Formule :C17H27N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.44Phenylsulfamide
CAS :Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and anFormule :C6H8N2O2SCouleur et forme :SolidMasse moléculaire :172.2α-Amylase, liquid
CAS :Degré de pureté :≥ 20,000U/gCouleur et forme :Brown liquidMasse moléculaire :-Pyrocatechol
CAS :Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Formule :C6H6O2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :110.11Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS :Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormule :C47H64N14O10Couleur et forme :SolidMasse moléculaire :985.1Carbonic anhydrase inhibitor 21
Compound 5h, known as Carbonic anhydrase inhibitor 21, is a specific inhibitor of carbonic anhydrase (hCA IX) with a K\(_i\) of 15.1 nM, demonstrating high selectivity compared to other isoforms studied. This compound is utilized in anticancer research.Formule :C32H48N4O10P2S2Masse moléculaire :774.22871TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingCouleur et forme :Odour SolidCAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Formule :C23H21N5O3SCouleur et forme :SolidMasse moléculaire :447.51Acesulfame
CAS :Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formule :C4H5NO4SCouleur et forme :SolidMasse moléculaire :163.15Proteinase K
CAS :Degré de pureté :≥ 30units/mg (pH 7.5, 37°C, dried basis)Couleur et forme :White or almost white lyophilized powderMasse moléculaire :-Peroxidase, from horseradish, approx. 200 U/mg
CAS :Degré de pureté :≥ 150U/mgCouleur et forme :Beige to light-brown, reddish brown or dark brown lyophilised powderMasse moléculaire :-Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Formule :C15H19NO3Couleur et forme :SolidMasse moléculaire :261.32β-Glucosidase, from almonds
CAS :Degré de pureté :approx. 90% (biuret)Couleur et forme :White to pale yellow or beige powderMasse moléculaire :-Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formule :C26H28N4O6S2Masse moléculaire :556.14503P-Hydroxybenzoate Hydroxylase
CAS :Couleur et forme :Yellowish lyophilised powderMasse moléculaire :55 ~ 60 kDaTyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Couleur et forme :Odour SolidCalmodulin-dependent Protein Kinase II fragment 290-309
CAS :Formule :C103H185N31O24SMasse moléculaire :2273.83Xanthine Oxidase, ammonium sulfate suspension
CAS :Couleur et forme :Faint brown to dark brown suspensionAnhydrotetracycline hydrochloride
CAS :Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.Formule :C22H23ClN2O7Degré de pureté :98% - 98.90%Couleur et forme :SolidMasse moléculaire :462.88DPP IV/hCA II-IN-1
CAS :DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).
Formule :C17H20N2O5SCouleur et forme :SolidMasse moléculaire :364.42CA IX/VEGFR-2-IN-3
CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.Formule :C19H16ClN3O5S2Couleur et forme :SolidMasse moléculaire :465.93CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Couleur et forme :Odour SolidTPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formule :C21H18N6O4SCouleur et forme :SolidMasse moléculaire :450.475,6-Dihydro-2H-pyran-2-one
CAS :5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Formule :C5H6O2Couleur et forme :SolidMasse moléculaire :98.1Tyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Couleur et forme :Odour SolidDOTA-XYIMSR-01
CAS :DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.57TrkA Protein, Canine, Recombinant (hFc)
TrkA Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :42.3 kDa (predicted); 55-61 kDa (reducing conditions)ErbB4 Protein, Human, Rhesus, Recombinant (hFc)
ErbB4 Protein, Human, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :96.6 kDa (predicted); 117 kDa (reducing conditions)Ref: TM-TMPY-02814
1mg4.207,00€5µg77,00€10µg109,00€20µg174,00€50µg350,00€100µg668,00€200µg1.017,00€500µg2.071,00€FLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :97.5%Couleur et forme :Lyophilized PowderMasse moléculaire :35.6 kDa (predicted)TrkB Protein, Human, Recombinant (His) V2
Expression System: HEK293 Cells
Length: 32-430, Extracellular Domain
Activity: ELISACouleur et forme :Lyophilized PowderMasse moléculaire :45.2 kDa (Predicted); 65-80 kDa (Due to glycosylation)HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :90-120 KDa (reducing condition)Mer Protein, Mouse, Recombinant (His & GST)
Mer Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.Couleur et forme :Lyophilized PowderMasse moléculaire :61.7 kDa (predicted); 58 kDa (reducing conditions)TrkB Protein, Human, Recombinant (His)
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :99.3%Couleur et forme :Lyophilized PowderMasse moléculaire :45.7 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)Thrombopoietin Protein, Mouse, Recombinant (C-His)
Expression System: HEK293 Cells
Length: 22-356, Full Length of Mature Protein
Activity: Cell ActivityCouleur et forme :Lyophilized PowderMasse moléculaire :37.20 kDa (Predicted); 75-95 kDa (Due to glycosylation)TrkA Protein, Rabbit, Recombinant (His)
TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :43.4 kDa (predicted)
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