Enzyme
Les inhibiteurs d'enzymes sont des molécules qui se lient aux enzymes et diminuent leur activité. Ces inhibiteurs sont largement utilisés en recherche pour étudier la cinétique enzymatique, la régulation et le rôle spécifique des enzymes dans les voies métaboliques. Les inhibiteurs d'enzymes sont également cruciaux dans le développement de médicaments, car de nombreux agents thérapeutiques agissent en inhibant les enzymes impliquées dans les processus pathologiques. En ciblant les enzymes, ces inhibiteurs peuvent moduler les voies biochimiques et offrir des traitements potentiels pour diverses maladies. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs d'enzymes de haute qualité pour soutenir vos recherches en biochimie, pharmacologie et découverte de médicaments.
Sous-catégories appartenant à la catégorie "Enzyme"
- Anhydrase carbonique(177 produits)
- Hydroxylase(30 produits)
- MPO(2 produits)
- Réductase(52 produits)
- Tyrosinase(67 produits)
3586 produits trouvés pour "Enzyme"
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DOTA-XYIMSR-01
CAS :<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.57CAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Formule :C23H21N5O3SCouleur et forme :SolidMasse moléculaire :447.51TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Formule :C21H18N6O4SCouleur et forme :SolidMasse moléculaire :450.47Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Formule :C15H19NO3Couleur et forme :SolidMasse moléculaire :261.32hCA/VEGFR-2-IN-2
<p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>Formule :C23H26N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.552-Methoxy-4-propylphenol
CAS :<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22CAIX Inhibitor S4
CAS :<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Formule :C15H17N3O4SDegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :335.38Peroxidase, from horseradish, approx. 200 U/mg
CAS :Degré de pureté :≥ 150U/mgCouleur et forme :Beige to light-brown, reddish brown or dark brown lyophilised powderMasse moléculaire :-Proteinase K
CAS :Degré de pureté :≥ 30units/mg (pH 7.5, 37°C, dried basis)Couleur et forme :White or almost white lyophilized powderMasse moléculaire :-Trypsin
CAS :Degré de pureté :≥ 250IU/mgCouleur et forme :White to off-white powderMasse moléculaire :-β-Amylase, from soy
CAS :Degré de pureté :≥ 10.0units/mgCouleur et forme :White to off-white powderMasse moléculaire :-Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS :<p>Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect</p>Formule :C47H64N14O10Couleur et forme :SolidMasse moléculaire :985.1hCAII-IN-6
<p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5IOX2-NH2-1
CAS :<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Formule :C19H17N3O5Degré de pureté :98.77% - 99.91%Couleur et forme :SoildMasse moléculaire :367.36hCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5DPP IV/hCA II-IN-1
CAS :<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formule :C17H20N2O5SCouleur et forme :SolidMasse moléculaire :364.42TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Couleur et forme :Odour SolidTSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Formule :C35H51N3O3Couleur et forme :SolidMasse moléculaire :561.798Chlorothiazide
CAS :<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Formule :C7H6ClN3O4S2Degré de pureté :98.46% - 98.91%Couleur et forme :Crystals Physical Description Crystals; White Powder (Ntp 1992)Masse moléculaire :295.72Phenylsulfamide
CAS :<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formule :C6H8N2O2SCouleur et forme :SolidMasse moléculaire :172.2Calmodulin-dependent Protein Kinase II fragment 290-309
CAS :Formule :C103H185N31O24SMasse moléculaire :2273.83Acesulfame
CAS :<p>Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.</p>Formule :C4H5NO4SCouleur et forme :SolidMasse moléculaire :163.15Pyrocatechol
CAS :<p>Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.</p>Formule :C6H6O2Couleur et forme :SolidMasse moléculaire :110.11Anhydrotetracycline hydrochloride
CAS :<p>Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.</p>Formule :C22H23ClN2O7Degré de pureté :98.90%Couleur et forme :SolidMasse moléculaire :462.88Xanthine Oxidase, ammonium sulfate suspension
CAS :Couleur et forme :Faint brown to dark brown suspensionhCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Couleur et forme :Odour SolidCarbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Couleur et forme :Odour SolidTyrosinase-IN-34
<p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>Formule :C19H14BrClN4OCouleur et forme :SolidMasse moléculaire :429.7CAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Couleur et forme :Odour SolidTyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Couleur et forme :Odour SolidPeroxidase
CAS :Degré de pureté :≥ 85units/mg (dry basis)Couleur et forme :Beige to light-brown, reddish brown or dark brown lyophilised powderMasse moléculaire :-
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