Enzyme
Les inhibiteurs d'enzymes sont des molécules qui se lient aux enzymes et diminuent leur activité. Ces inhibiteurs sont largement utilisés en recherche pour étudier la cinétique enzymatique, la régulation et le rôle spécifique des enzymes dans les voies métaboliques. Les inhibiteurs d'enzymes sont également cruciaux dans le développement de médicaments, car de nombreux agents thérapeutiques agissent en inhibant les enzymes impliquées dans les processus pathologiques. En ciblant les enzymes, ces inhibiteurs peuvent moduler les voies biochimiques et offrir des traitements potentiels pour diverses maladies. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs d'enzymes de haute qualité pour soutenir vos recherches en biochimie, pharmacologie et découverte de médicaments.
Sous-catégories appartenant à la catégorie "Enzyme"
- Anhydrase carbonique(177 produits)
- Hydroxylase(30 produits)
- MPO(2 produits)
- Réductase(52 produits)
- Tyrosinase(67 produits)
3586 produits trouvés pour "Enzyme"
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hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Couleur et forme :Odour SolidhCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5hCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Formule :C13H10FN3O4Masse moléculaire :291.06553VM4-037
CAS :<p>VM4-037 is a PET imaging agent used for carbonic anhydrase IX.</p>Formule :C26H29FN6O7S2Couleur et forme :SolidMasse moléculaire :620.67Calmodulin-dependent Protein Kinase II fragment 290-309
CAS :Formule :C103H185N31O24SMasse moléculaire :2273.83hCA/VEGFR-2-IN-3
<p>hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.</p>Formule :C24H28N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.58Xanthine Oxidase, ammonium sulfate suspension
CAS :Couleur et forme :Faint brown to dark brown suspensionhCAII-IN-8
CAS :<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Formule :C15H16N2O5SDegré de pureté :99.73%Couleur et forme :SoildMasse moléculaire :336.36Carbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Couleur et forme :Odour SolidCAXII-IN-2
<p>CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.</p>Formule :C16H13FNO4PCouleur et forme :SolidMasse moléculaire :333.05662hCAI/II-IN-10
<p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>Formule :C24H17Cl2N3O3S2Couleur et forme :SolidMasse moléculaire :530.446Tyrosinase-IN-38
<p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>Couleur et forme :Odour SolidCAIX Inhibitor S4
CAS :<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Formule :C15H17N3O4SDegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :335.38hCAIX-IN-19
<p>hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/</p>Couleur et forme :Odour SolidCAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Couleur et forme :Odour SolidTyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Couleur et forme :Odour SolidDOTA-XYIMSR-01
CAS :<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.57IOX2-NH2-1
CAS :<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Formule :C19H17N3O5Degré de pureté :98.77% - 99.91%Couleur et forme :SoildMasse moléculaire :367.365,6-Dihydro-2H-pyran-2-one
CAS :<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Formule :C5H6O2Couleur et forme :SolidMasse moléculaire :98.1TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Formule :C21H18N6O4SCouleur et forme :SolidMasse moléculaire :450.47DPP IV/hCA II-IN-1
CAS :<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formule :C17H20N2O5SCouleur et forme :SolidMasse moléculaire :364.42Glucose Oxidase
CAS :Degré de pureté :≥ 100U/mgCouleur et forme :Pale yellow to dark yellow powderMasse moléculaire :-Proteinase K
CAS :Degré de pureté :≥ 30units/mg (pH 7.5, 37°C, dried basis)Couleur et forme :White or almost white lyophilized powderMasse moléculaire :-hCAII-IN-6
<p>"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Peroxidase
CAS :Degré de pureté :≥ 85units/mg (dry basis)Couleur et forme :Beige to light-brown, reddish brown or dark brown lyophilised powderMasse moléculaire :-P-Hydroxybenzoate Hydroxylase
CAS :Couleur et forme :Yellowish lyophilised powderMasse moléculaire :55 ~ 60 kDa2-Methoxy-4-propylphenol
CAS :<p>2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.</p>Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22Phenylsulfamide
CAS :<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formule :C6H8N2O2SCouleur et forme :SolidMasse moléculaire :172.2Carbonic anhydrase inhibitor 30
<p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>Formule :C23H22FN3O5SCouleur et forme :SolidMasse moléculaire :471.12642TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Couleur et forme :Odour SolidTrypsin, bovine origin
CAS :Degré de pureté :≥ 2000units/mg (USP)Couleur et forme :White or almost white crystalline powderMasse moléculaire :-hCA/VEGFR-2-IN-4
<p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>Formule :C22H23FN6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.52α-Amylase, liquid
CAS :Degré de pureté :≥ 20,000U/gCouleur et forme :Brown liquidMasse moléculaire :-
