Enzyme
Les inhibiteurs d'enzymes sont des molécules qui se lient aux enzymes et diminuent leur activité. Ces inhibiteurs sont largement utilisés en recherche pour étudier la cinétique enzymatique, la régulation et le rôle spécifique des enzymes dans les voies métaboliques. Les inhibiteurs d'enzymes sont également cruciaux dans le développement de médicaments, car de nombreux agents thérapeutiques agissent en inhibant les enzymes impliquées dans les processus pathologiques. En ciblant les enzymes, ces inhibiteurs peuvent moduler les voies biochimiques et offrir des traitements potentiels pour diverses maladies. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs d'enzymes de haute qualité pour soutenir vos recherches en biochimie, pharmacologie et découverte de médicaments.
Sous-catégories appartenant à la catégorie "Enzyme"
- Anhydrase carbonique(196 produits)
- Hydroxylase(36 produits)
- MPO(2 produits)
- Réductase(51 produits)
- Tyrosinase(71 produits)
3619 produits trouvés pour "Enzyme"
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Lysozyme - Enzyme activity min 40000 FIP/mg
CAS :Lysozyme is a bacteriolytic enzyme, which is primarily derived from hen egg whites. It functions by hydrolyzing the β-1,4-glycosidic linkages in the peptidoglycan layer of bacterial cell walls, particularly in Gram-positive bacteria. This enzymatic activity results in the lysis and subsequent death of the bacterial cells, providing a potent antimicrobial effect.Couleur et forme :PowderNucleoside phosphorylase from microorganisms
CAS :Nucleoside phosphorylase (Purine nucleoside phosphorylase, PNP, PNPase, inosine phosphorylase, inosine-guanosine phosphorylase; EC 2.4.2.1) is an enzyme that catalyzes the following reaction: purine nucleoside + Pi ⇌ purine + alpha-D-ribose 1-phosphate One unit of nucleoside phosphorylase will phosphorylate 1.0 micromole of inosine to hypoxanthine and alpha-D-ribose 1-phosphate per min at pH 7.4 and 25°C.Formule :C5H6ClN3Degré de pureté :Min. 95%Masse moléculaire :143.57 g/molβ-Galactosidase >100KU/g
CAS :beta-Galactosidase (EC 3.2.1.23, shortly beta-Gal, also know as lactase) catalyses the hydrolysis of beta-d-galactoside in the presence of water to galactose and alcohol, or lactose into glucose and galactose. beta-Gal has a molecular weight of 540,000 and is composed of four identical subunits of MW 135,000, each with an independent active site. The enzyme has divalent metals as cofactors, with chelated Mg2+ ions required to maintain active site conformation. The molecule contains numerous sulfhydryl groups and is glycosylated.Couleur et forme :PowderAcetylcholinesterase, type VI-S, 200-1,000 units/mg protein
CAS :Acetylcholinesterase is an enzyme that breaks down acetylcholineDegré de pureté :Min. 95%Couleur et forme :PowderEWP 815
CAS :EWP 815, a disulfiram analog, inhibits Ins(1,4)P2, Ins(1,4,5)P3 phosphatases, and dopamine β-hydroxylase.Formule :C12H22N4S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.59Carbonic anhydrase inhibitor 12
CAS :CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.Formule :C27H22BrN5O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :640.53ALP/Carbonic anhydrase-IN-1
CAS :Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkalineFormule :C15H16N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.3hCAIX-IN-16
CAS :hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.Formule :C20H20N8O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49hCAIX-IN-15
CAS :hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFormule :C18H14FN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.41Sezolamide hydrochloride
CAS :Sezolamide hydrochloride is a potent topical carbonic anhydrase inhibitor.Formule :C11H19ClN2O4S3Couleur et forme :SolidMasse moléculaire :374.93hCAIX/XII-IN-8
CAS :hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.Formule :C16H13Cl2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.28N-Desethyl Brinzolamide oxalate
CAS :N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].Formule :C12H19N3O9S3Couleur et forme :SolidMasse moléculaire :445.49Sezolamide
CAS :Sezolamide is a carbonic anhydrase inhibitor.Formule :C11H18N2O4S3Couleur et forme :SolidMasse moléculaire :338.47COX-2-IN-30
CAS :COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =Formule :C17H16N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.41LX-1031
CAS :LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.Formule :C28H25F3N4O4Degré de pureté :97.123% - 98.97%Couleur et forme :SolidMasse moléculaire :538.52Ref: TM-T15796
1mg55,00€5mg120,00€10mg187,00€25mg376,00€50mg597,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)143,00€CAXII-IN-1
CAS :CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.Formule :C13H7Cl2NO3SCouleur et forme :SolidMasse moléculaire :328.17Diethyl-pythiDC
CAS :Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.Formule :C14H14N2O4SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :306.34Triose phosphate isomerase
CAS :Triose-phosphate isomerase (TPI, TIM; EC 5.3.1.1) is an enzyme that catalyzes the reversible isomerisation of dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate: DHAP ⇌ GADP The reaction mechanism involves the formation of an enediol intermediate. One unit of Triose-phosphate isomerase will convert 1.0 μmole glyceraldehyde 3-phosphate to dihydroxyacetone phosphate per min at pH 7.6 and 25 °C.Degré de pureté :Min. 95%Sulfatase, from helix pomatia ≥10,000 units/g solid
CAS :Sulfatase from Helix pomatia is a highly potent enzyme that is capable of hydrolyzing sulfated compounds and sulfate esters. It has been widely used in various applications such as glucosinolate analysis, genistein extraction preparation, and regiospecificity studies. With a concentration of ≥10,000 units per gram of solid, this sulfatase offers exceptional enzymatic activity for sulfatase assays. It effectively catalyzes the hydrolysis of sulfated substrates, including p-nitrocatechol sulfate, naphthyl sulfate and phenyl sulfates.The enzyme can be incubated with the desired sample to facilitate the release of sulfate groups from sulfated compounds. Sulfatase from Helix pomatia is a valuable tool for researchers and scientists working in diverse fields requiring efficient and reliable enzymatic hydrolysis capabilities. Additionally the enzyme has been found to have industrial applications, such as in the bioconversion of industrial chemicals, where it can be used as a catalyst.
Couleur et forme :PowderOxalate Oxidase, freeze-dried, from Wheat
CAS :Oxalate Oxidase, freeze-dried, is an enzymatic preparation that serves as a catalyst in biochemical reactions. This enzyme is derived from wheat, a common plant source, ensuring a naturally occurring origin. Its primary mode of action is the oxidation of oxalate into carbon dioxide and hydrogen peroxide. This biochemical activity is significant in various scientific applications, specifically in the breakdown of oxalate, which plays a crucial role in metabolic and environmental processes.Couleur et forme :PowderThioredoxin reductase from escherichia coli
CAS :Thioredoxin reductase (TR, TrxR) (EC 1.8.1.9) is an enzyme that reduce thioredoxin using NADPH as a co-factor, and also contains FAD. One unit of thioredoxin reductase will raise increase light absorbance by 1.0 per minute at 412nm in the presence of thioredoxin and Ellman's reagent at pH 7.0 and 25 °C.Degré de pureté :Min. 95%Glycerol 3-phosphate oxidase, from pediococcus sp., 40-84U/mg
CAS :Glycerol-3-phosphate oxidase (EC 1.1.3.21) is an enzyme that catalyzes the following reaction: glycerol-3-phosphate + O2 ⇌ dihydroxyacetone phosphate + H2O2 One unit of Glycerol-3-phosphate oxidase will generate 1.0 μmole H2O2 per min at 37°C, under the presence of O2 and the optimal pH. If required, you can remove the build-up of hydrogen peroxide using catalase.Degré de pureté :Min. 95%Glycerokinase, cellulomonas species
CAS :Glycerokinase (glycerol kinase, GP, ATP-glycerol 3-phosphotransferase; EC 2.7.1.30) is an enzyme that catalyzes the following reaction: ATP + glycerol ⇌ ADP + glycerol 3-phosphate One unit of Glycerokinase will convert 1.0 μmole of glycerol and ATP to glycerol 3-phosphate and ADP per min at pH 9.8 and 25 °C.Couleur et forme :Powderp-Ethynylphenylalanine
CAS :p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki ofFormule :C11H11NO2Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :189.21β-Glucuronidase from Helix pomatia - Type H-2, aqueous solution, ≥85,000 units/mL
CAS :β-Glucuronidase (EC 3.2.1.31) is an enzyme that hydrolyzes glucuronides. It can also be used to cleave benzodiazepine and steroid conjugates. One unit of β-Glucuronidase will hydrolyze a chromogenic substrate mimic 4-nitrophenyl-β-D-glucuronide to produce 1.0 μmole of 4-nitrophenol per minute at pH 5.0 and 37 °C.Degré de pureté :Min. 95%Couleur et forme :Clear LiquidSarcosine oxidase from bacillus sp., >15 units/mg solid, lyophilized powder
CAS :Sarcosine oxidase (Monomeric sarcosine oxidase, MSOX, EC 1.5.3.1) is an enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2 and formaldehyde in the following reaction: CH3-NH2+-CH2-COO- + H2O + O2 → NH3+-CH2-COO- + H2O2 + CH2O or sarcosine + water + oxygen → glycine + hydrogen peroxyde + formaldehydeOne unit of Sarcosine oxidase will form 1.0 micromole of formaldehyde from sarcosine per minute at pH 8.3 and 37 °C. You can remove the build-up of hydrogen peroxide using catalase.Formule :C10H12N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :292.25 g/molTyrosinase-IN-33
CAS :Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.Formule :C19H17NS2Couleur et forme :SolidMasse moléculaire :323.48hCAII-IN-5
CAS :hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Formule :C29H18N2O7Couleur et forme :SolidMasse moléculaire :506.46Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Formule :C15H17N3O3SCouleur et forme :SolidMasse moléculaire :319.38CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.Formule :C16H22N4O8SCouleur et forme :SolidMasse moléculaire :430.43hCA VB-IN-1
hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].Formule :C9H13N3O4SCouleur et forme :SolidMasse moléculaire :259.28hCAIX-IN-20
CAS :hCAIX-IN-20 (compound APBS-5m) is a potent inhibitor of carbonic anhydrase IX (hCA IX), with a Ki of 2.7 nM, playing a significant role in cancer research.Formule :C19H13Cl2N5O4S2Masse moléculaire :510.37CA IX-IN-3
CAS :CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.Formule :C21H19N5O4S2Couleur et forme :SolidMasse moléculaire :469.537hCAI/II/XII-IN-1
CAS :hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.Formule :C12H12N2O2SCouleur et forme :SolidMasse moléculaire :248.301Tyrosinase-IN-29
CAS :Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.Formule :C10H9NO2Couleur et forme :SolidMasse moléculaire :175.18Carbonic anhydrase inhibitor 16
CAS :Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.Formule :C14H10N2O4SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :302.31O-Desmethyl Brinzolamide hydrochloride
CAS :O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].Formule :C11H20ClN3O5S3Couleur et forme :SolidMasse moléculaire :405.94Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.Formule :C24H20ClN3O3SCouleur et forme :SolidMasse moléculaire :465.95hCAVII/IX-IN-1
CAS :hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.Formule :C7H7N3O2S2Couleur et forme :SolidMasse moléculaire :229.279Tyrosinase-IN-35
CAS :Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Formule :C17H15N5OSCouleur et forme :SolidMasse moléculaire :337.40Perfluorohexane sulfonamide
CAS :Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.Formule :C6H2F13NO2SCouleur et forme :SolidMasse moléculaire :399.13Isobutylamido thiazolyl resorcinol
CAS :Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.Formule :C13H14N2O3SCouleur et forme :SolidMasse moléculaire :278.33hCAII-IN-3
hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.
Formule :C17H21N3O3SCouleur et forme :SolidMasse moléculaire :347.43Carbonic anhydrase inhibitor 9
Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.Formule :C22H20BrN5O4SCouleur et forme :SolidMasse moléculaire :530.39NSC 828467
NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).Formule :C21H19N9O2SCouleur et forme :SolidMasse moléculaire :461.5CAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Formule :C19H21FN4SCouleur et forme :SolidMasse moléculaire :356.46β-Glucuronidase/hCAII-IN-1
CAS :β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50Formule :C30H21NO9Couleur et forme :SolidMasse moléculaire :539.49CAII-IN-2
CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.Formule :C18H19BrN4SCouleur et forme :SolidMasse moléculaire :403.34hCAIX/XII-IN-15
CAS :hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.Formule :C17H18O4SCouleur et forme :SolidMasse moléculaire :318.387Carbonic anhydrase inhibitor 8
R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5
