Transporteur membranaire/Canal ionique
Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.
Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"
- ABC(3 produits)
- ATPase(101 produits)
- Récepteur de l'adiponectine(5 produits)
- CFTR(65 produits)
- Récepteur CGRP(54 produits)
- Canal calcique(541 produits)
- Canal chlorure(53 produits)
- Récepteur GABA(365 produits)
- Transporteur de monoamine(30 produits)
- Transporteur de monocarboxylate(18 produits)
- NKCC(2 produits)
- NPC1L1(3 produits)
- Cotransporteur Na-K-Cl(10 produits)
- OAT(32 produits)
- OCT(7 produits)
- P-gp(55 produits)
- Canal potassique(280 produits)
- Pompe à protons(42 produits)
- SGLT(31 produits)
- Canal sodique(209 produits)
- Canal TRP/TRPV(95 produits)
Affichez 13 plus de sous-catégories
2514 produits trouvés pour "Transporteur membranaire/Canal ionique"
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Nav1.8-IN-4
CAS :Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.Formule :C20H14F4N2O3Degré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :406.33Ref: TM-T77693
1mg59,00€2mg85,00€5mg125,00€10mg188,00€25mg376,00€50mg612,00€100mg938,00€500mg1.882,00€Omeprazole metabolite Omeprazole sulfone
CAS :Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.Formule :C17H19N3O4SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :361.42Ref: TM-T12309
1mg49,00€2mg65,00€5mg97,00€10mg154,00€25mg298,00€50mg445,00€100mg642,00€500mg1.320,00€1mL*10mM (DMSO)106,00€Pentetrazol
CAS :Pentylenetetrazol is a GABA(A) receptor antagonist, that displays activity as a central nervous system and respiratory stimulant.Formule :C6H10N4Degré de pureté :99.67% - 99.90%Couleur et forme :Bitter Taste Aqueous Solutions Neutral To Litmus (Ntp 1992)Masse moléculaire :138.17Nikethamide
CAS :Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of endFormule :C10H14N2ODegré de pureté :99.42%Couleur et forme :Followed By A Faint Sensation Of The Warmth (Ntp 1992)Masse moléculaire :178.23NaV1.7 inhibitor-1
CAS :NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Formule :C23H30FNO4SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :435.55Ref: TM-T12181
1mg104,00€5mg255,00€10mg406,00€25mg700,00€50mg938,00€100mg1.378,00€1mL*10mM (DMSO)280,00€ML418
CAS :ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formule :C19H24ClN3O3Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :377.87Ref: TM-T16110
1mg39,00€5mg84,00€10mg117,00€25mg188,00€50mg304,00€100mg437,00€200mg615,00€1mL*10mM (DMSO)93,00€DCPIB
CAS :<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Formule :C22H28Cl2O4Degré de pureté :99.79% - 99.87%Couleur et forme :SolidMasse moléculaire :427.36Flumazenil
CAS :Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervousFormule :C15H14FN3O3Degré de pureté :99.72% - 99.98%Couleur et forme :Less Crystals Colourless CrystalsMasse moléculaire :303.29Isoguvacine hydrochloride
CAS :<p>Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist.</p>Formule :C6H10ClNO2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :163.6NS1652
CAS :<p>NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.</p>Formule :C15H11F3N2O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :324.25Ethaverine hydrochloride
CAS :Ethaverine hydrochloride is a homologue of papaverine and is used as a vasodilator and antispasmodic.Cost-effective and quality-assured.Formule :C24H30ClNO4Degré de pureté :99.66% - 99.90%Couleur et forme :SolidMasse moléculaire :431.96Ref: TM-T0369
2mg47,00€5mg66,00€10mg107,00€25mg177,00€50mg264,00€100mg378,00€200mg558,00€1mL*10mM (DMSO)89,00€CIQ
CAS :CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. EC50 value: 2.7 μM for NR2C and 2.8 μM for NR2D.Formule :C26H26ClNO5Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :467.94BI-749327
CAS :BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).Formule :C23H21F3N4O2Degré de pureté :99.68% - 99.84%Couleur et forme :SolidMasse moléculaire :442.43Ref: TM-T10537
1mg133,00€2mg177,00€5mg274,00€10mg432,00€25mg630,00€50mg825,00€100mg1.103,00€500mg2.205,00€1mL*10mM (DMSO)301,00€Torsemide
CAS :<p>Torsemide (AC-4464), a sulfonylurea loop diuretic, has a long action duration, high plasma protein binding, and a long half-life.</p>Formule :C16H20N4O3SDegré de pureté :99.81%Couleur et forme :Crystalline SolidMasse moléculaire :348.42NMDA-IN-1
CAS :<p>NMDA-IN-1 is a potent and NR2B-selective antagonist of NMDA(NMDA Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM).</p>Formule :C20H23ClFN3ODegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :375.87EN6
CAS :EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.Formule :C19H14F2N4O2Degré de pureté :95.74% - 97.04%Couleur et forme :SolidMasse moléculaire :368.34Ref: TM-T11191
1mg47,00€5mg88,00€10mg137,00€25mg205,00€50mg264,00€100mg400,00€500mg909,00€1mL*10mM (DMSO)70,00€Methocarbamol
CAS :Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formule :C11H15NO5Degré de pureté :99.96%Couleur et forme :Crystals From Benzene SolidMasse moléculaire :241.24Diphenidol hydrochloride
CAS :Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.Formule :C21H28ClNODegré de pureté :99.15% - 99.33%Couleur et forme :Crystals Soluble In Methanol WaterMasse moléculaire :345.91Fluxametamide
CAS :Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).Formule :C20H16Cl2F3N3O3Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :474.26γ-Aminobutyric acid
CAS :γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.Formule :C4H9NO2Degré de pureté :99.95%Couleur et forme :White Or Almost White(According To Quality Test Specification It Can Be White Or Almost White ) Solid PowderMasse moléculaire :103.12NS13001
CAS :NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formule :C17H16ClN7Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :353.81Flindokalner
CAS :Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.Formule :C16H10ClF4NO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :359.7Devapamil
CAS :Devapamil (Devapamilo) is a phenylalkylamine that blocks L-type calcium currents from the inner side of membrane cells in a use-dependent manner.Formule :C26H36N2O3Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :424.58Pramocaine hydrochloride
CAS :Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.Formule :C17H27NO3·HClDegré de pureté :99.15% - 99.61%Couleur et forme :Crystals White Or Off White Crystalline PowderMasse moléculaire :329.86Disopyramide
CAS :Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formule :C21H29N3ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :339.47Dooku1
CAS :Dooku1, Yoda1 analog, blocks Piezo1 channels, halting Ca2+ entry. IC50: 1.3μM in HEK 293, 1.5μM in HUVEC, stops Yoda1's aortic relaxation.Formule :C13H9Cl2N3OSDegré de pureté :98.87% - 99.74%Couleur et forme :SolidMasse moléculaire :326.2Ref: TM-T11076
1mg46,00€2mg59,00€5mg87,00€10mg140,00€25mg274,00€50mg510,00€100mg735,00€1mL*10mM (DMSO)96,00€Ciclopirox olamine
CAS :Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.Formule :C14H24N2O3Degré de pureté :99.16% - >99.99%Couleur et forme :White To Yellow Solid Solid Particulate/PowderMasse moléculaire :268.353,4,5-Trimethoxycinnamic acid
CAS :3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at theFormule :C12H14O5Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :238.241-EBIO
CAS :1-EBIO (1-EBIO) is a calium channel agonist.Formule :C9H10N2ODegré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :162.19Manidipine dihydrochloride
CAS :Manidipine dihydrochloride (Manidipine 2HCl) is a potent calcium channel blocker for Ca2+ current(IC50=2.6 nM).Formule :C35H40Cl2N4O6Degré de pureté :99.76% - 99.86%Couleur et forme :SolidMasse moléculaire :683.62NBQX disodium
CAS :NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formule :C12H6N4Na2O6SDegré de pureté :97.32% - 97.6%Couleur et forme :SolidMasse moléculaire :380.2415Indapamide
CAS :Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Formule :C16H16ClN3O3SDegré de pureté :98.97% - 99.83%Couleur et forme :SolidMasse moléculaire :365.83Prilocaine hydrochloride
CAS :Prilocaine HCl: local amino amide anesthetic, blocks voltage-gated sodium channels in neurons, inhibits Na+ permeability.Formule :C13H21ClN2ODegré de pureté :99.97%Couleur et forme :Needles White Or Off White Crystalline PowderMasse moléculaire :256.77Tocainide hydrochloride
CAS :<p>Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker.</p>Formule :C11H17ClN2ODegré de pureté :97%Couleur et forme :SolidMasse moléculaire :228.72Bupivacaine hydrochloride
CAS :Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formule :C18H28N2O·HClDegré de pureté :99.89% - 99.9%Couleur et forme :SolidMasse moléculaire :324.89Penicillin G sodium salt
CAS :<p>Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a</p>Formule :C16H17N2NaO4SDegré de pureté :98.11%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :356.37Bemegride
CAS :Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.Formule :C8H13NO2Degré de pureté :99.89%Couleur et forme :Physical Description White Crystalline Solid Sublimes At 212°F And 200 Mm Pressure (Ntp 1992)Masse moléculaire :155.19IK1 inhibitor PA-6
CAS :IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFormule :C31H32N4O2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :492.61Nefiracetam
CAS :Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Formule :C14H18N2O2Degré de pureté :97.37%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :246.3BMS-394136
CAS :BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Formule :C24H21Cl2FN4ODegré de pureté :98.59% - 99.95%Couleur et forme :SolidMasse moléculaire :471.35T16Ainh-A01
CAS :T16Ainh-A01 is a potent TMEM16A chloride channel inhibitor with a 1 μM IC50, targeting CaCC.Formule :C19H20N4O3S2Degré de pureté :97.18% - 98.15%Couleur et forme :SolidMasse moléculaire :416.52Ref: TM-T13059
1mg35,00€5mg66,00€10mg97,00€25mg183,00€50mg280,00€100mg425,00€200mg615,00€1mL*10mM (DMSO)87,00€Z433927330
CAS :<p>Z433927330 is a potent and selective Aquaporin-7 (AQP7) inhibitor(IC50s of 0.2).</p>Formule :C20H20N4O3Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :364.4Lotilaner
CAS :Lotilaner is a parasiticide.Formule :C20H14Cl3F6N3O3SDegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :596.76Ref: TM-T15775
1mg44,00€2mg58,00€5mg94,00€10mg144,00€25mg335,00€50mg550,00€100mg882,00€200mg1.188,00€1mL*10mM (DMSO)111,00€Moxidectin
CAS :Moxidectin (CL301423) is an anthelmintic for heartworm/intestinal worms in dogs, cats, horses, cattle, and sheep; oral/topical/injectable.Formule :C37H53NO8Degré de pureté :97.38%Couleur et forme :Appearance White Or Pale Yellow Amorphous PowderMasse moléculaire :639.82Dibucaine
CAS :Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.Formule :C20H29N3O2Degré de pureté :99.698% - 99.88%Couleur et forme :Colorless Or Almost Colorless Powder SolidMasse moléculaire :343.46FFN 206 dihydrochloride
CAS :<p>FFN 206 dihydrochloride: fluorescent VMAT2 marker, detects subcellular sites, non-inhibitory to DAT.</p>Formule :C12H15ClN2O2Degré de pureté :98.96% - >99.99%Couleur et forme :SolidMasse moléculaire :254.71Ethosuximide
CAS :Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied byFormule :C7H11NO2Degré de pureté :98.87% - 99.72%Couleur et forme :Crystals From Acetone And Ether SolidMasse moléculaire :141.17Pivagabine
CAS :Pivagabine (CXB-722), a 4-aminobutyric acid derivative, modulates GABA, CRF, and crosses the rat blood-brain barrier.Formule :C9H17NO3Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :187.24DMT1 blocker 2
CAS :Compound 12f, a DMT1 blocker, inhibits DMT1 with a 0.83 IC50, potentially blocking intestinal iron absorption.Formule :C16H13N3ODegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :263.29Ref: TM-T11064
1mg92,00€5mg188,00€10mg354,00€25mg597,00€50mg852,00€100mg1.159,00€1mL*10mM (DMSO)215,00€Domperidone EP Impurity A
CAS :Domperidone EP Impurity A is used as pharmaceutical intermediates.Formule :C12H14ClN3ODegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :251.71Phenibut
CAS :Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).Formule :C10H13NO2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :179.22γ-DGG acetate(6729-55-1 free base)
CAS :gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.Formule :C9H16N2O7Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :264.23GET73
CAS :GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.Formule :C13H16F3NO2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :275.27Ref: TM-T11393
5mg42,00€10mg59,00€25mg110,00€50mg166,00€100mg243,00€200mg359,00€1mL*10mM (DMSO)47,00€Etimizol
CAS :Etimizol improves memory by aiding the consolidation stage, effective against amnesia from hypoxia or brain injury.Formule :C9H14N4O2Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :210.23Oxybuprocaine hydrochloride
CAS :Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.Formule :C17H29ClN2O3Degré de pureté :>99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :344.88Tertiapin-Q
CAS :Tertiapin-Q is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner, inhibiting efflux to K(+).Formule :C106H175N35O24S4Degré de pureté :98.06% - 98.09%Couleur et forme :SolidMasse moléculaire :2452Glimepiride
CAS :Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.Formule :C24H34N4O5SDegré de pureté :97.84% - 98.87%Couleur et forme :White Cyrstalline SolidMasse moléculaire :490.62CGP37157
CAS :CGP37157 (7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one) is a Na+/Ca2+ exchanger inhibitor, inhibits Na+-induced Ca2+ release fromFormule :C15H11Cl2NOSDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :324.22Butamben
CAS :Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Formule :C11H15NO2Degré de pureté :99.43%Couleur et forme :Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Masse moléculaire :193.24Trichlormethiazide
CAS :Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics.Formule :C8H8Cl3N3O4S2Degré de pureté :98.8% - 99.54%Couleur et forme :SolidMasse moléculaire :380.66D-AP5
CAS :D-AP5 (D-APV) is a NMDA receptor antagonist.Formule :C5H12NO5PDegré de pureté :98.77% - >99.99%Couleur et forme :White Fine Crystalline PowderMasse moléculaire :197.13N-Acetylprocainamide
CAS :N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmicFormule :C15H23N3O2Degré de pureté :99.65% - 99.74%Couleur et forme :SolidMasse moléculaire :277.36AZD 7009
CAS :AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.Formule :C23H34N4O5Degré de pureté :98.42% - 98.51%Couleur et forme :SoildMasse moléculaire :446.54GsMTx4
CAS :GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).Formule :C185H273N49O45S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4095.84AChE/Aβ-IN-1
AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting theFormule :C20H25BrN4Couleur et forme :SolidMasse moléculaire :401.34EVT-401
EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].Formule :C22H20F4N2O3Couleur et forme :SolidMasse moléculaire :436.4Nitrazolam
CAS :Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Formule :C17H13N5O2Couleur et forme :SolidMasse moléculaire :319.32Elgodipine
CAS :Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.Formule :C29H33FN2O6Degré de pureté :99.84% - 99.98%Couleur et forme :SolidMasse moléculaire :524.58Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Degré de pureté :96.97%Couleur et forme :SolidMambalgin 1
CAS :ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.Formule :C272H429N85O84S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6554.51(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS :(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Formule :C6H11NO2Couleur et forme :SolidMasse moléculaire :129.163-Aminopropylphosphinic acid
CAS :<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formule :C3H10NO2PCouleur et forme :SolidMasse moléculaire :123.092Leptomycin A
CAS :<p>Leptomycin A from Streptomyces inhibits CRM1, reducing HIV-1 replication, less potent than Leptomycin B, blocks protein nuclear export.</p>Formule :C32H46O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :526.7Cavα2δ-IN-1
CAS :Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a KiFormule :C18H27N5OCouleur et forme :SolidMasse moléculaire :329.448TRPA1-IN-1
CAS :TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.Formule :C19H17ClN6O3Couleur et forme :SolidMasse moléculaire :412.83CHET3
CAS :CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.Formule :C21H21N5O3SDegré de pureté :98.28% - 99.92%Couleur et forme :SoildMasse moléculaire :423.49LY-466195
CAS :LY-466195 is a competitive antagonist of GLUK5 receptor.Formule :C16H24F2N2O4Couleur et forme :SolidMasse moléculaire :346.37BeKm-1
CAS :Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.Formule :C174H261N51O52S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4091.65Huwentoxin I
CAS :Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Formule :C161H246N48O44S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3750.36GpTx-1 TFA
GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.Couleur et forme :Odour SolidWAY-326766
CAS :WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Formule :C21H23N3O5Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :397.42TP-050
CAS :TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.Formule :C16H15ClF2N6OCouleur et forme :SolidMasse moléculaire :380.78Cevadine
Cevadine is a natural product that can be used as a reference standard.Formule :C32H49NO9Couleur et forme :SolidMasse moléculaire :591.742Atagabalin
CAS :Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Formule :C10H19NO2Couleur et forme :SolidMasse moléculaire :185.26TRPA1 Antagonist 3
CAS :TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.Formule :C11H8ClN3Couleur et forme :SolidMasse moléculaire :217.6617α-Hydroxywithanolide D
<p>17alpha-Hydroxywithanolide D is an allosteric modulator of the NMDA receptor, with an IC50 of 44.24 nM. This compound exhibits neuroprotective properties and can be utilized in Alzheimer's disease research.</p>Formule :C28H46O7Couleur et forme :SolidMasse moléculaire :494.661Chlorotoxin TFA
Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.Formule :C160H250F3N53O49S11Couleur et forme :SolidMasse moléculaire :4109.74Hyp9
CAS :Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].Formule :C18H26O5Couleur et forme :SolidMasse moléculaire :322.40Homocarnosine
CAS :Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.Formule :C10H16N4O3Couleur et forme :SolidMasse moléculaire :240.26JAMI1001A
CAS :JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.Formule :C16H17F3N4O3SCouleur et forme :SolidMasse moléculaire :402.39AChE/Aβ-IN-2
AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.Formule :C20H25ClN4Couleur et forme :SolidMasse moléculaire :356.89SLC26A3-IN-2
CAS :Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.Formule :C19H13ClN2O2SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :368.8417(S)-HETE
CAS :<p>Arachidonic acid and its CYP450 metabolite, 17(S)-HETE, regulate kidney electrolytes; 17(S)-HETE reduces proximal tubule ATPase activity by 70% at 2 μM.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.473Anticonvulsant agent 9
Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.Formule :C22H24N4O2Couleur et forme :SolidMasse moléculaire :376.45Crofelemer
CAS :Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.Couleur et forme :SolidIdactamab
CAS :Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :146.2 kDaAmpullosporin A
CAS :Ampullosporin A is a peptaibol-type polypeptide isolated from the fungus Sepedonium ampullosporum (HKI-0053), exhibiting neuromodulatory activity. It inhibits hyperactivity induced by the NMDA receptor antagonist MK-801 and ameliorates social behavior abnormalities caused by subchronic ketamine treatment. Ampullosporin A modulates glutamate receptor activity without affecting dopamine D1 and D2 receptors.Formule :C77H127N19O19Couleur et forme :SolidMasse moléculaire :1622.95Levamlodipine besylate Hemipentahydrate
CAS :<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formule :C20H25ClN2O5·C6H6O3SH2OCouleur et forme :SolidMasse moléculaire :1224.18Analgesic/antidepressant agent-1
<p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>Formule :C22H25ClN2O2Couleur et forme :SolidMasse moléculaire :384.9α,β-Methylene-ATP dilithium
CAS :α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors.Formule :C11H16Li2N5O12P3Couleur et forme :SolidMasse moléculaire :517.07
