Transporteur membranaire/Canal ionique
Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.
Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"
- ABC(3 produits)
- ATPase(101 produits)
- Récepteur de l'adiponectine(5 produits)
- CFTR(65 produits)
- Récepteur CGRP(54 produits)
- Canal calcique(543 produits)
- Canal chlorure(53 produits)
- Récepteur GABA(366 produits)
- Transporteur de monoamine(30 produits)
- Transporteur de monocarboxylate(18 produits)
- NKCC(2 produits)
- NPC1L1(3 produits)
- Cotransporteur Na-K-Cl(10 produits)
- OAT(32 produits)
- OCT(7 produits)
- P-gp(55 produits)
- Canal potassique(280 produits)
- Pompe à protons(42 produits)
- SGLT(31 produits)
- Canal sodique(210 produits)
- Canal TRP/TRPV(96 produits)
Affichez 13 plus de sous-catégories
2534 produits trouvés pour "Transporteur membranaire/Canal ionique"
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Huwentoxin I
CAS :Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Formule :C161H246N48O44S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3750.36NSC799462
NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a designated site on the p97 enzyme. This interaction induces localized structural alterations in p97, effectively inhibiting its ATPase activity with an IC 50 value of 15 nM.Formule :C30H32F2N6O3SCouleur et forme :SolidMasse moléculaire :594.68Linoleic Acid Amide
CAS :<p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>Formule :C18H33NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.46Levamlodipine besylate Hemipentahydrate
CAS :Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.Formule :C20H25ClN2O5·C6H6O3SH2OCouleur et forme :SolidMasse moléculaire :1224.18NMDA receptor antagonist 2
CAS :Potent, oral NR2B-selective NMDA receptor antagonist; IC50 of 1.0 nM, Ki of 0.88 nM; used for neuropathic pain and Parkinson's research.Formule :C20H21N7OCouleur et forme :SolidMasse moléculaire :375.4363-Aminopropylphosphonic Acid
CAS :<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Formule :C3H10NO3PDegré de pureté :99.84%Couleur et forme :Light Yellow LiquidMasse moléculaire :139.09(R)-Funapide
CAS :(R)-Funapide ((R)-TV 45070), the less active R-enantiomer of Funapide, acts as a potent Nav1.7 sodium channel blocker, primarily utilized in pain research [1].Formule :C22H14F3NO5Couleur et forme :SolidMasse moléculaire :429.35Charybdotoxin
CAS :Specific inhibitor of the big conductance Ca2+-activated K+ channel.Formule :C176H277N57O55S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4295.9517(R)-Resolvin D1
CAS :Resolvins are anti-inflammatory lipids from EPA and DHA. Resolvin D1, made from DHA, and its aspirin-triggered epimer 17(R)-RvD1, inhibit acute inflammation.Formule :C22H32O5Couleur et forme :SolidMasse moléculaire :376.493Concanamycin B
CAS :Concanamycin B, a macrolide, inhibits V-ATPases (IC50 = 5 nM), blocks vacuole acidification, affects bone resorption, CD8 T cells, and MHC II in B cells.Formule :C45H73NO14Couleur et forme :SolidMasse moléculaire :852.072Cyclic ADP-Ribose (ammonium salt)
Cyclic ADP-Ribose (ammonium salt) (cADPR) is an NAD⁺ metabolite that triggers Ca²⁺ release from ER stores via ryanodine receptors, relevant to inflammation research.Formule :C15H21N5O13P2·xNH3Couleur et forme :SolidSulcardine 2HCl
CAS :Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formule :C24H35Cl2N3O4SDegré de pureté :99.33% - 99.76%Couleur et forme :SoildMasse moléculaire :532.523AZD-3161
CAS :AZD-3161 is a sodium channel regulator for pain.Formule :C23H21F3N4O4Couleur et forme :SolidMasse moléculaire :474.43Fumitremorgin C
CAS :<p>Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.</p>Formule :C22H25N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.45Cevadine
Cevadine is a natural product that can be used as a reference standard.Formule :C32H49NO9Couleur et forme :SolidMasse moléculaire :591.742SNX-482
CAS :Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.Formule :C192H274N52O60S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4495.01Verruculogen
CAS :Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.Formule :C27H33N3O7Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :511.57Homocarnosine
CAS :Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.Formule :C10H16N4O3Couleur et forme :SolidMasse moléculaire :240.26LU-32-176B
CAS :LU32-176B is a bioactive chemical.Formule :C23H24F2N2O2Couleur et forme :SolidMasse moléculaire :398.45LY 274614
CAS :LY 274614 is a structurally novel systemically active competitive NMDA receptor antagonist.Formule :C11H20NO5PCouleur et forme :SolidMasse moléculaire :277.25L-Palmitoylcarnitine TFA
<p>L-Palmitoylcarnitine TFA: long-chain fat metabolite that disrupts membranes in ischaemia & inhibits KATP channels via Kir6.2 interaction.</p>Formule :C25H46F3NO6Couleur et forme :SolidMasse moléculaire :513.63TNP-ATP triethylammonium salt
CAS :P2X receptor antagonistFormule :C40H77N12O19P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1123.042GABA-IN-1
GABA-IN-1 (Compound 6), a GABA inhibitor, exhibits larvicidal and insecticidal properties, achieving a mortality rate of 93% at a concentration of 50 mg/L [1].Couleur et forme :Odour SolidCP-628006
CAS :CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.Formule :C32H35F3N2O2Couleur et forme :SolidMasse moléculaire :536.639Lifastuzumab
CAS :Sulfamethoxazole-NO (SMX-NO) is a SMX-NO derivative and is the primary immunogen for sulfonamide hypersensitivity reactions.Degré de pureté :97% (SDS-PAGE); 99.5% (SEC-HPLC) - 97% (SDS-PAGE); 99.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaG-Glu-Ser
CAS :G-Glu-Ser is a calcium receptor activator and Flavor-enriching agent.Formule :C8H14N2O6Couleur et forme :SolidMasse moléculaire :234.21Halazone
CAS :Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.Formule :C7H5Cl2NO4SDegré de pureté :98.64%Couleur et forme :Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Masse moléculaire :270.09Chlorocresol
CAS :Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Formule :C7H7ClOCouleur et forme :SolidMasse moléculaire :142.58L-R4W2
CAS :Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.Formule :C46H71N21O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1014.2Brevetoxin B
CAS :Brevetoxin B, a polyketide neurotoxin from Karenia, affects sodium channels causing neurotoxic shellfish poisoning. IC50=15nM.Formule :C50H70O14Couleur et forme :SolidMasse moléculaire :895.096AmmTX3
KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.Formule :C158H262N50O48S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3822.47(±)17-HETE
CAS :<p>Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.473GDC-0334
CAS :GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.Formule :C24H19F8N5O3SCouleur et forme :SolidMasse moléculaire :609.5PptT-IN-4
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.Formule :C17H23N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.38Mesoridazine free base
CAS :Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine.Formule :C21H26N2OS2Couleur et forme :SolidMasse moléculaire :386.57Way 125971
CAS :Way 125971 is a bioactive chemcial.Formule :C22H28N4O5S2Couleur et forme :SolidMasse moléculaire :492.61PNU-140975
CAS :PNU-140975 is a bio-active chemical.Formule :C3H9N5O2Couleur et forme :SolidMasse moléculaire :147.1383-Aminopropylphosphinic acid
CAS :<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formule :C3H10NO2PCouleur et forme :SolidMasse moléculaire :123.092Venturicidin A
CAS :Venturicidin A is a macrolide antibiotic.Formule :C41H67NO11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :749.97NF864
CAS :NF864, a suramin analog, is a P2X1 receptor inhibitor.Formule :C57H28N6Na12O41S12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2113.5GaTx2
CAS :High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Formule :C125H199N39O47S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3192.54Lyso-Globotriaosylceramide (d18:1)
CAS :Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.Formule :C36H67NO17Couleur et forme :SolidMasse moléculaire :785.922Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Formule :C17H16N6O3SCouleur et forme :SolidMasse moléculaire :384.41Huwentoxin-IV
CAS :Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.Formule :C174H278N52O51S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4106.79GluN2A Allosteric modulator 1
GluN2A Allosteric modulator 1 (Compound 11) is an orally bioavailable compound that effectively crosses the blood-brain barrier and functions as a highly selective negative allosteric modulator of GluN2A. It exhibits an IC50 of 0.042 μM for GluN2A and 13 μM for GluN2B. This compound is useful for research in neurological disorders.Formule :C20H16ClF2N5O2Couleur et forme :SolidMasse moléculaire :431.823RuBi-GABA
CAS :Ruthenium-bipyridine-triphenylphosphine caged GABAFormule :C42H39F6N5O2P2RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :922.8CHET3
CAS :CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.Formule :C21H21N5O3SDegré de pureté :98.28% - 99.92%Couleur et forme :SoildMasse moléculaire :423.494-oxo-2-Nonenal
CAS :<p>4-Hydroxy Nonenal and 4-oxo-2-Nonenal are lipid peroxidation byproducts, signaling oxidative stress and possibly causing mutagenesis.</p>Formule :C9H14O2Couleur et forme :SolidMasse moléculaire :154.209ω-Agatoxin TK
CAS :<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Formule :C215H337N65O70S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5273.02Lei-Dab7
CAS :Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.Formule :C141H236N46O39S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3392.06(R)-IDHP
CAS :(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.Formule :C12H16O5Couleur et forme :SolidMasse moléculaire :240.25SC 4453
CAS :SC 4453 is a digoxin analog and a cardiac glycoside derivative.Formule :C41H64N2O12Couleur et forme :SolidMasse moléculaire :776.965N-Arachidonoyl Taurine
CAS :N-Arachidonoyl taurine, an amino acid, activates TRPV1/TRPV4, is metabolized by lipoxygenase, and affects insulin secretion and calcium flux.Formule :C22H37NO4SCouleur et forme :SolidMasse moléculaire :411.6GSK2332255B
CAS :<p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>Formule :C18H19ClFN3O3SCouleur et forme :SolidMasse moléculaire :411.88WAY-326766
CAS :WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).Formule :C21H23N3O5Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :397.42BeKm-1
CAS :Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.Formule :C174H261N51O52S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4091.654'-hydroxy Trazodone
CAS :<p>4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is</p>Formule :C19H22ClN5O2Couleur et forme :SolidMasse moléculaire :387.87Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Couleur et forme :Odour SolidATP Synthesis-IN-1
ATP Synthesis-IN-1 (Compound 4), a quinoline derivative, potently inhibits PA ATP synthesis with an IC50 of 11.1μg/mL and exhibits antibacterial properties.Couleur et forme :Odour SolidAnticancer agent 108
Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to bothFormule :C18H9NO5S2Couleur et forme :SolidMasse moléculaire :383.412,14-Dichlorodehydroabietic acid
CAS :12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Formule :C20H26Cl2O2Couleur et forme :SolidMasse moléculaire :369.33OD1
Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.Formule :C308H466N90O95S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7206.1SG-094
CAS :<p>SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.</p>Formule :C30H29NO3Degré de pureté :97.06%Couleur et forme :SoildMasse moléculaire :451.56TRPV1 activator-1
CAS :TRPV1 Activator-1 (Compound 8), a capsaicin analog featuring a modified neck structure, specifically interacts with the T551 residue [1].Formule :C18H27NO2SCouleur et forme :SolidMasse moléculaire :321.488-Azido-ATP
CAS :8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties.Formule :C10H15N8O13P3Couleur et forme :SolidMasse moléculaire :548.19Trans (2,3)-Dihydrotetrabenazine
CAS :<p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>Formule :C19H29NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.44Kurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)Formule :C324H478N94O90S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7386.36Atagabalin
CAS :Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Formule :C10H19NO2Couleur et forme :SolidMasse moléculaire :185.26AQP4 (201-220)
CAS :AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.Formule :C97H143N27O27SCouleur et forme :SolidMasse moléculaire :2151.4Flufiprole
CAS :Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.Formule :C16H10Cl2F6N4OSCouleur et forme :SolidMasse moléculaire :491.24Iberiotoxin
CAS :<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formule :C179H274N50O55S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4230Mambalgin 1
CAS :ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.Formule :C272H429N85O84S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6554.51A 80915A
CAS :A80915A: Semi-naphthoquinone antibiotic, blocks gastric (H(+)-K+)-ATPase; potency varies with enzyme conformation; K+ reduces binding rate.Formule :C26H31Cl3O5Couleur et forme :SolidMasse moléculaire :529.88CALP3
CAS :Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.Formule :C44H68N10O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :881.08APETx2 TFA
APETx2 TFA from sea anemone is a selective ASIC3 inhibitor with a 63 nM IC50, reversing acid and inflammatory pain.Formule :C198H281F3N54O62S6Couleur et forme :SolidMasse moléculaire :4675.02C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
CAS :C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group inFormule :C48H83NO18Couleur et forme :SolidMasse moléculaire :962.181GluN2B-NMDAR antagonist-1
Orally active GluN2B-NMDAR antagonist with neuroprotective properties for ischemic injury research.Formule :C26H23BrN2O2Couleur et forme :SolidMasse moléculaire :475.38MRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formule :C21H14N5NaO3SCouleur et forme :SolidMasse moléculaire :439.42Anisatin
Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.Formule :C15H20O8Couleur et forme :SolidMasse moléculaire :328.317Leptomycin A
CAS :Leptomycin A from Streptomyces inhibits CRM1, reducing HIV-1 replication, less potent than Leptomycin B, blocks protein nuclear export.Formule :C32H46O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :526.7Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Couleur et forme :Odour SolidDihydroisopimaric acid
CAS :Dihydroisopimaric acid opens BKαβ1 channels - large Ca²⁺-activated K⁺ conductors, verified by whole-cell voltage clamp.Formule :C20H32O2Couleur et forme :SolidMasse moléculaire :304.478-Bromo-ATP
CAS :8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and an ATP analogue.Formule :C10H15BrN5O13P3Couleur et forme :SolidMasse moléculaire :586.077Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.Couleur et forme :Odour SolidLRRK2-IN-15
LRRK2-IN-15 is an inhibitor of LRRK2. It exhibits an IC50 value of 5 nM in PBMC cells and 1.5 μM for BCRP. This compound is utilized in the research of Parkinson's disease.Couleur et forme :Odour SolidML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Formule :C19H15FN2ODegré de pureté :99.98% - 99.98%Couleur et forme :SoildMasse moléculaire :306.33Ref: TM-T67917
5mg49,00€10mg79,00€25mg120,00€50mg164,00€100mg230,00€200mg314,00€1mL*10mM (DMSO)52,00€Sinapine hydroxide
CAS :Sinapine hydroxide from crucifer seeds has anti-inflammatory, anti-oxidant, anti-tumor properties, and inhibits AChE, aiding neurodegenerative research.Formule :C16H25NO6Couleur et forme :SolidMasse moléculaire :327.377Guangxitoxin 1E
CAS :Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.Formule :C178H248N44O45S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3948.61Tariquidar methanesulfonate hydrate
CAS :m-PEG8-Ms is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC compounds.Formule :C40H58N4O18S2Degré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :947.04FD 12-9
CAS :FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.Formule :C51H47N3O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :877.93Ethacrynic acid D5
CAS :Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Formule :C13H12Cl2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.17Digoxigenin Monodigitoxoside
CAS :Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.Formule :C29H44O8Couleur et forme :SolidMasse moléculaire :520.663P-gp/BCRP-IN-2
P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRPFormule :C32H35N3O6Couleur et forme :SolidMasse moléculaire :557.64Sandaracopimaric acid
CAS :Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Formule :C20H30O2Couleur et forme :SolidMasse moléculaire :302.45Nitrazolam
CAS :Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Formule :C17H13N5O2Couleur et forme :SolidMasse moléculaire :319.32(R)-Lanicemine
CAS :(R)-Lanicemine ((R)-AZD6765), an R-enantiomer with less activity, is a low-trapping NMDA blocker with antidepressant effects.Formule :C13H14N2Couleur et forme :SolidMasse moléculaire :198.26Tariquidar dimesylate
CAS :Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.Formule :C80H94N8O25S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1695.9JYL-79
CAS :JYL-79 is an agonist of the vanilloid receptor.Formule :C26H36N2O4SCouleur et forme :SolidMasse moléculaire :472.64Ebio3
Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.Formule :C19H23F2N3O2Couleur et forme :SolidMasse moléculaire :363.4AQP4 (205-215) TFA
AQP4 (205-215) TFA is a fragment of the water channel protein-4 (AQP4). AQP4 acts as an autoimmune antigen in neuromyelitis optica, upregulating and presenting in B cells upon binding with CD40. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).Couleur et forme :Odour Solid
