Transporteur membranaire/Canal ionique
Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.
Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"
- ABC(3 produits)
- ATPase(93 produits)
- Récepteur de l'adiponectine(5 produits)
- CFTR(64 produits)
- Récepteur CGRP(51 produits)
- Canal calcique(493 produits)
- Canal chlorure(49 produits)
- Récepteur GABA(336 produits)
- Transporteur de monoamine(23 produits)
- Transporteur de monocarboxylate(17 produits)
- NKCC(2 produits)
- NPC1L1(3 produits)
- Cotransporteur Na-K-Cl(8 produits)
- OAT(27 produits)
- OCT(7 produits)
- P-gp(53 produits)
- Canal potassique(276 produits)
- Pompe à protons(39 produits)
- SGLT(30 produits)
- Canal sodique(202 produits)
- Canal TRP/TRPV(92 produits)
Affichez 13 plus de sous-catégories
2270 produits trouvés pour "Transporteur membranaire/Canal ionique"
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Gramicidin S
CAS :<p>Gramicidin S (Gramicidin Soviet), a cationic cyclic peptide antibiotic, disrupts the membrane integrity of both Gram-positive and Gram-negative bacteria and</p>Formule :C60H92N12O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1141.45Dc1a
<p>Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).</p>Formule :C276H414N76O84S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6397.22BDBM50597431
CAS :<p>BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.</p>Formule :C27H43F3O2Degré de pureté :98.64% - 99.28%Couleur et forme :SoildMasse moléculaire :456.62Furosemide
CAS :<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Formule :C12H11ClN2O5SDegré de pureté :99.32% - 99.89%Couleur et forme :Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Masse moléculaire :330.744GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37OD1
<p>Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.</p>Formule :C308H466N90O95S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7206.1NMDA agonist 2
<p>NMDA agonist 2 (compound 8d) effectively inhibits NMDA receptors, exhibiting an EC50 of 0.034 μM for GluN1/2C. It plays a significant role in neurological and psychiatric disorders.</p>Formule :C14H12BrFN2O3SCouleur et forme :SolidMasse moléculaire :387.224Ebio2
<p>Ebio2 is an effective activator of KCNQ2.</p>Formule :C17H19F2N3O2Couleur et forme :SolidMasse moléculaire :335.349Huwentoxin I
CAS :<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Formule :C161H246N48O44S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3750.36Mambalgin 1
CAS :<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formule :C272H429N85O84S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6554.51BKCa activator-1
<p>BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.</p>Formule :C22H23F7N2O3Couleur et forme :SolidMasse moléculaire :496.418GX 201
CAS :<p>GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.</p>Formule :C25H27ClF4N2O4SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :563N-Oleoyl Valine Ammonium salt
<p>N-Oleoyl Valine Ammonium salt is an N-acyl amide compound that is a TRPV3 antagonist and can be used to study inflammation.</p>Formule :C23H46N2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :398.62Ethacrynic acid D5
CAS :<p>Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.</p>Formule :C13H12Cl2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.17α5-GABAA receptor modulator 1
<p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>Formule :C21H20FN3O4Couleur et forme :SolidMasse moléculaire :397.4GaTx2
CAS :<p>High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.</p>Formule :C125H199N39O47S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3192.54AQP4 (201-220)
CAS :<p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Formule :C97H143N27O27SCouleur et forme :SolidMasse moléculaire :2151.4Cavα2δ-IN-1
CAS :<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formule :C18H27N5OCouleur et forme :SolidMasse moléculaire :329.448Tenapanor HCl
CAS :<p>Tenapanor (AZD-1722, RDX 5791) inhibits NHE3 for sodium control in the gut and kidneys.</p>Formule :C50H68Cl6N8O10S2Couleur et forme :SolidMasse moléculaire :1217.97Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formule :C19H38ClN5O2SCouleur et forme :SolidMasse moléculaire :436.06Agitoxin-2
CAS :<p>Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).</p>Formule :C169H278N54O48S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4090.87Huwentoxin-IV
CAS :<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Formule :C174H278N52O51S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4106.79Withaphysalin D
CAS :<p>Withaphysalin D, from water lilies, blocks GluN2B NMDARs and is neuroprotective, crossing the blood-brain barrier.</p>Formule :C28H34O6Couleur et forme :SolidMasse moléculaire :466.57GDC-0334
CAS :<p>GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.</p>Formule :C24H19F8N5O3SCouleur et forme :SolidMasse moléculaire :609.5Inaperisone
CAS :<p>Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.</p>Formule :C16H23NODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :245.36GsMTx4
CAS :<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formule :C185H273N49O45S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4095.84PNU-140975
CAS :<p>PNU-140975 is a bio-active chemical.</p>Formule :C3H9N5O2Couleur et forme :SolidMasse moléculaire :147.138Way 125971
CAS :<p>Way 125971 is a bioactive chemcial.</p>Formule :C22H28N4O5S2Couleur et forme :SolidMasse moléculaire :492.61PptT-IN-4
<p>PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.</p>Formule :C17H23N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.38P-gp inhibitor 15
<p>P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123</p>Formule :C35H60N2O4Couleur et forme :SolidMasse moléculaire :572.86Isotachysterol 3
CAS :<p>Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.</p>Formule :C27H44OCouleur et forme :SolidMasse moléculaire :384.64Roquefortine C
CAS :<p>Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins</p>Formule :C22H23N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.45(R)-Funapide
CAS :<p>(R)-Funapide ((R)-TV 45070), the less active R-enantiomer of Funapide, acts as a potent Nav1.7 sodium channel blocker, primarily utilized in pain research [1].</p>Formule :C22H14F3NO5Couleur et forme :SolidMasse moléculaire :429.35GluN2A Allosteric modulator 1
<p>GluN2A Allosteric modulator 1 (Compound 11) is an orally bioavailable compound that effectively crosses the blood-brain barrier and functions as a highly selective negative allosteric modulator of GluN2A. It exhibits an IC50 of 0.042 μM for GluN2A and 13 μM for GluN2B. This compound is useful for research in neurological disorders.</p>Formule :C20H16ClF2N5O2Couleur et forme :SolidMasse moléculaire :431.823Cevadine
<p>Cevadine is a natural product that can be used as a reference standard.</p>Formule :C32H49NO9Couleur et forme :SolidMasse moléculaire :591.742S-Sulfo-L-cysteine sodium salt
CAS :<p>S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.</p>Formule :C3H6NNaO5S2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :223.2Sulcardine 2HCl
CAS :<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Formule :C24H35Cl2N3O4SDegré de pureté :99.33% - 99.76%Couleur et forme :SoildMasse moléculaire :532.523AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Formule :C20H25BrN4Couleur et forme :SolidMasse moléculaire :401.34Trapencaine
CAS :<p>Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.</p>Formule :C22H34N2O3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :374.52XPO1-ligand-1
<p>XPO1-ligand-1 is a target protein ligand for XPO1, and it can be utilized in the synthesis of PROTAC XPO1 degrader-1.</p>Formule :C15H13ClF3N3O4Couleur et forme :SolidMasse moléculaire :391.73GYKI-47261 dihydrochloride
CAS :<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formule :C18H17Cl3N4Degré de pureté :98.32% - 99.14%Couleur et forme :SolidMasse moléculaire :395.71Mambalgin-3
<p>Mambalgin-3, an acid-sensitive ion channel 1 (ASIC1) inhibitor, has potential applications in analgesia research [1].</p>Formule :C274H433N85O83S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6566.54Jingzhaotoxin-X
<p>Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].</p>Formule :C164H242N46O41S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3706.35sFTX-3.3
CAS :<p>sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.</p>Formule :C12H29N7OCouleur et forme :SolidMasse moléculaire :287.412Nicardipine-d3 hydrochloride
CAS :<p>Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.</p>Formule :C26H30ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519Halofantrine hydrochloride
CAS :<p>Halofantrine hydrochloride (SKF-102886) is an orally administered antimalarial drug effective against drug-resistant P. falciparum and P. vivax. SKF-102886 has cardiac toxicity, inhibiting hERG and delayed rectifier potassium channel I Kr, leading to prolonged QTc and PR intervals.</p>Formule :C26H31Cl3F3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.89(S)-Nicardipine
CAS :<p>(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Formule :C26H29N3O6Couleur et forme :SolidMasse moléculaire :479.53Jedi2
CAS :<p>Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1].</p>Formule :C10H8O3SDegré de pureté :97.85%Couleur et forme :SolidMasse moléculaire :208.23β-D-Glucopyranosyl abscisate
CAS :<p>β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable conjugate of abscisic acid (ABA), which predominantly accumulates in the vacuole and likely in the</p>Formule :C21H30O9Couleur et forme :SolidMasse moléculaire :426.46NS-102
CAS :<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Formule :C12H11N3O4Degré de pureté :98.48% - 98.95%Couleur et forme :SolidMasse moléculaire :261.23Norverapamil-d7
CAS :<p>Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .</p>Formule :C26H36N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.62Fluoroethylnormemantine hydrochloride
CAS :<p>Fluoroethylnormemantine HCl, an NMDA receptor antagonist, has anti-amnesic, neuroprotective effects, and is a PET tracer.</p>Formule :C12H21ClFNCouleur et forme :SolidMasse moléculaire :233.764-(4-chlorophenyl)piperidin-4-ol
CAS :<p>Compound Fr13199 is a useful organic compound for research related to life sciences. The catalog number is Fr13199 and the CAS number is 39512-49-7.</p>Formule :C11H14ClNODegré de pureté :99.63%Couleur et forme :White Slight Beige Solid Solid Particulate/PowderMasse moléculaire :211.688Phenazopyridine
CAS :<p>Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.</p>Formule :C11H11N5Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :213.24Perfluoroenanthic acid
CAS :<p>Perfluoroenanthic acid (Perfluoroheptanoic acid) is a perfluoroalkyl substance (PFAS) that negatively impacts spermatogenic development and testicular m6A RNA methylation in offspring exposed during gestation, thus impeding spermatogenesis and inducing reproductive toxicity. Additionally, in primary cortical neuron cultures, Perfluoroenanthic acid alters dendritic spine morphology and synaptogenesis, enhances neural activity and synaptic transmission, and increases the expression of excitatory synapse-associated proteins Synaptophysin and PSD95.</p>Formule :C7HF13O2Couleur et forme :SolidMasse moléculaire :364.06Dipropofol
CAS :<p>Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.</p>Formule :C24H34O2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :354.53NS 383
CAS :<p>ASIC blocker with varying IC50: 0.12 μM in hASIC1a, and ineffective on hASIC2a/3; <5 μM on rASIC1a/2a/3; alleviates pain in inflamed/CCI rats.</p>Formule :C19H19N3O2Couleur et forme :SolidMasse moléculaire :321.37MSC-4381
CAS :<p>MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4/SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.</p>Formule :C26H20ClN3O6SDegré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :537.97Propanidid
CAS :<p>Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and an intravenous anesthetic that lowers arterial blood pressure.</p>Formule :C18H27NO5Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :337.41BI-9627
CAS :<p>BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).</p>Formule :C16H19F3N4O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :356.34GYKI 52466 dihydrochloride
CAS :<p>GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.</p>Formule :C17H17Cl2N3O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :366.24(R)-3-Amino-4-hydroxybutanoic acid
CAS :<p>(R)-3-Amino-4-hydroxybutanoic acid,L-beta-Homoserine, is a full agonist at the human recombinant rho1 GABAC receptor, a modulator of GABAA and GABAB receptors.</p>Formule :C4H9NO3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :119.12Cromakalim
CAS :<p>Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.</p>Formule :C16H18N2O3Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :286.33L-3373
CAS :<p>L-3373 is a competitive T3 (3,5,3'-triiodothyronine) antagonist with IC₅₀ values of 38 and 36 nM for alpha1-T3R and beta1-T3R, respectively.</p>Formule :C19H16I2O3Degré de pureté :99.85%Couleur et forme :Off-White SolidMasse moléculaire :546.14Fanapanel hydrate
CAS :<p>Fanapanel hydrate selectively blocks AMPA/kainate over NMDA; Ki: 3.2 nM (quisqualate), 100 nM (kainate), 8.5 μM (NMDA).</p>Formule :C14H17F3N3O7PCouleur et forme :SolidMasse moléculaire :427.27Piretanide
CAS :<p>Piretanide, an oral loop diuretic, effective and potassium-sparing, heart failure and hypertension with reduced electrolyte imbalance risk.</p>Formule :C17H18N2O5SCouleur et forme :Pale Yellow PowderMasse moléculaire :362.4MDL 105519
CAS :<p>MDL 105519 is a selective, non-competitive antagonist of NMDA receptors. It inhibits cyclic GMP accumulation in brain slices, anxiolytic in rat models.</p>Formule :C18H11Cl2NO4Couleur et forme :SolidMasse moléculaire :376.19Naminidil
CAS :<p>Naminidil is an opener of cyanoguanidine KATP.</p>Formule :C15H19N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.34Furosemide-d5
CAS :<p>Furosemide-d5 is a deuterium marker for Furosemide and used in isotope tracer experiments. orally active inhibitor of Na+/K+/2Cl- (NKCC) diuretic reagent.</p>Formule :C12H11ClN2O5SCouleur et forme :SolidMasse moléculaire :335.78Lesinurad sodium
CAS :<p>Lesinurad sodium (RDEA594 sodium) is a selective inhibitor of uric acid reabsorption and is used in the study of cardiovascular diseases.</p>Formule :C17H13BrN3NaO2SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :426.26Flecainide
CAS :<p>Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.</p>Formule :C17H20F6N2O3Degré de pureté :99.896%Couleur et forme :SolidMasse moléculaire :414.345-Hydroxydecanoic acid
CAS :<p>5-Hydroxydecanoic acid is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoic acid is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity.</p>Formule :C10H20O3Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :188.26γ-DGG
CAS :<p>gamma-DGG is a competitive blocker of AMPA receptor.</p>Formule :C7H12N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :204.18Lansoprazole Sulfide D4
CAS :<p>Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.</p>Formule :C16H14F3N3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.39Padsevonil
CAS :<p>Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.</p>Formule :C14H14ClF5N4O2SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :432.80(S)-Lercanidipine D3 hydrochloride
CAS :<p>(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.</p>Formule :C36H42ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :651.21Etifoxine
CAS :<p>Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.</p>Formule :C17H17ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.78Rapastinel
CAS :<p>Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.</p>Formule :C18H31N5O6Degré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :413.47PF-05198007
CAS :<p>PF-05198007 is a compound with a similar pharmacodynamic profile to PF-05089771. PF-05198007 is an effective and selective arylsulfonamide Nav1.7 inhibitor.</p>Formule :C19H12ClF4N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :533.91L-655708
CAS :<p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>Formule :C18H19N3O4Degré de pureté :98.41%Couleur et forme :PowderMasse moléculaire :341.36Naspm
CAS :<p>Naspm is a synthetic analogue of Joro spider toxin and is a antagonist iscalcium permeable AMPA (CP-AMPA) receptors.</p>Formule :C22H34N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.53KCNQ1 activator-1
CAS :<p>N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.</p>Formule :C22H23N3O4S2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :457.57Ethacizine hydrochloride
CAS :<p>Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity and can be used to study arrhythmias and myocardial infarction.</p>Formule :C22H28ClN3O3SDegré de pureté :98.08% - 98.08%Couleur et forme :SolidMasse moléculaire :449.99BTD
CAS :<p>BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.</p>Formule :C24H33N3O4SCouleur et forme :SolidMasse moléculaire :459.6Ethyl tosylcarbamate
CAS :<p>Gliclazide blocks beta-cell ATP-sensitive K+ currents, IC50: 184 nM. Ethyl tosylcarbamate is a synthesis intermediate.</p>Formule :C10H13NO4SCouleur et forme :SolidMasse moléculaire :243.28H-D-Allo-Ile-OH
CAS :<p>H-D-Allo-Ile-OH inhibits 3[H] gabapentin binding/voltage-dependent L-type calcium channels and can be used for studying neurological and psychiatric disorders.</p>Formule :C6H13NO2Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :131.17AM-2099
CAS :<p>AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.</p>Formule :C19H13F3N4O3S2Couleur et forme :SolidMasse moléculaire :466.46Vigabatrin Hydrochloride
CAS :<p>Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.</p>Formule :C6H11NO2·HClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.62CGP 36742
CAS :<p>CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).</p>Formule :C7H18NO2PCouleur et forme :SolidMasse moléculaire :179.2MRK-016
CAS :<p>MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.</p>Formule :C17H20N8O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :368.39GYKI 53655 hydrochloride
CAS :<p>GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.</p>Formule :C19H21ClN4O3Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :388.85β-Cyfluthrin
CAS :<p>β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.</p>Formule :C22H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :434.29Lubiprostone hemiketal
CAS :<p>Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.</p>Formule :C20H32F2O5Couleur et forme :SolidMasse moléculaire :390.46Neosolaniol
CAS :<p>Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.</p>Formule :C19H26O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.4Crinecerfont hydrochloride
CAS :<p>SSR-125543, a potent CRF1 receptor non-peptide antagonist, effective in CAH research, taken orally.</p>Formule :C27H29Cl2FN2OSCouleur et forme :SolidMasse moléculaire :519.5Flumazenil acid
CAS :<p>Flumazenil is an antagonist of GABAA receptor. Flumazenil acid is a metabolite of Flumazenil.</p>Formule :C13H10FN3O3Couleur et forme :SolidMasse moléculaire :275.24Mepivacaine
CAS :<p>Mepivacaine (Carbocaine) is an amide local anesthetic, blocking sodium channels for nerve blocks and epidurals.</p>Formule :C15H22N2ODegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :246.35(R)-BPO-27
CAS :<p>(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the study of diarrhoea and polycystic kidney.</p>Formule :C26H18BrN3O6Degré de pureté :99.1%Couleur et forme :SolidMasse moléculaire :548.34(+)-SJ733
CAS :<p>(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.</p>Formule :C24H16F4N4O2Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :468.4Tetrabenazine-d6
CAS :<p>Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.</p>Formule :C19H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.46Valnoctamide
CAS :<p>Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.</p>Formule :C8H17NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :143.23VU041
CAS :<p>VU041 inhibits mosquito Kir1 channels (IC50: An. gambiae 2.5μM, Ae. aegypti 1.7μM), less on mammalian Kir2.1 (12.7μM), and minimally on other Kir channels.</p>Formule :C19H20F3N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.38YM-244769 dihydrochloride
CAS :<p>YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.</p>Formule :C26H24Cl2FN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.39(R)-Tegoprazan
CAS :<p>(R)-Tegoprazan, a benzimidazole derivative, inhibits kidney H+/K+-ATPase (IC50: 98 nM). Potential in GI disease research.</p>Formule :C20H19F2N3O3Couleur et forme :SolidMasse moléculaire :387.38PF-04856264
CAS :<p>PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.</p>Formule :C20H15N5O3S2Degré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :437.5(R)-Lercanidipine-d3 hydrochloride
CAS :<p>(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.</p>Formule :C36H42ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :651.21Bamaquimast
CAS :<p>Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.</p>Formule :C16H21N3O3Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :303.36Pirmenol hydrochloride
CAS :<p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>Formule :C22H31ClN2OCouleur et forme :SolidMasse moléculaire :374.95L-Palmitoylcarnitine
CAS :<p>L-Palmitoylcarnitine (L-PC) inhibits Na/K ATPase activity and potentiates fibrinolytic enzymes and tPA to inhibit thrombosis.</p>Formule :C23H45NO4Degré de pureté :97% - 99.81%Couleur et forme :SolidMasse moléculaire :399.61GI-530159
CAS :<p>TREK1/2 activator, selective over TRAAK/TASK3; hyperpolarizes neurons, depresses activity (EC50 = 0.76 μM).</p>Formule :C27H20F6N2O2Couleur et forme :White CrystalsMasse moléculaire :518.45(-)-α-Pinene
CAS :<p>(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission,</p>Formule :C10H16Degré de pureté :98.02% - 98.60%Couleur et forme :Colourless LiquidMasse moléculaire :136.23Clamikalant sodium
CAS :<p>Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.</p>Formule :C19H21ClN3NaO5S2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :493.96MRS1845
CAS :<p>MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).</p>Formule :C21H22N2O6Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :398.41Benzocaine hydrochloride
CAS :<p>Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and</p>Formule :C9H11NO2·HClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :201.65Triamterene D5
CAS :<p>Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic.</p>Formule :C12H11N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.29QO-58
CAS :<p>QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory pain</p>Formule :C18H8Cl2F4N4ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :443.18L-364,373
CAS :<p>KV7.1 (KCNQ1) channel activator</p>Formule :C25H20FN3OCouleur et forme :SolidMasse moléculaire :397.44SDZ 220-581 hydrochloride
CAS :<p>SDZ 220-581 hydrochloride is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).</p>Formule :C16H18Cl2NO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.2Tetramethrin
CAS :<p>Tetramethrin is a type I pyrethroid insecticide that affects the inactivation process of sodium channels in insect neurons, prolonged sodium currents.</p>Formule :C19H25NO4Degré de pureté :98.85%Couleur et forme :White Crystals Or PowderMasse moléculaire :331.41Poneratoxin acetate
<p>Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.</p>Formule :C129H215N33O31S·xC2H4O2Couleur et forme :SolidMasse moléculaire :2756.35 (free base)BI-9627 hydrochloride
CAS :<p>BIX HCl is a sodium-hydrogen exchange type 1 inhibitor.</p>Formule :C16H20ClF3N4O2Couleur et forme :SolidMasse moléculaire :392.8HSK16149
CAS :<p>HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.</p>Formule :C12H19NO2Couleur et forme :SolidMasse moléculaire :209.28SDZ 220-581 Ammonium salt
CAS :<p>SDZ 220-581 Ammonium salt is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).</p>Formule :C16H20ClN2O5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.77TACA
CAS :<p>GABAA agonist</p>Formule :C4H7NO2Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :101.1Dibucaine hydrochloride
CAS :<p>Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.</p>Formule :C20H30ClN3O2Degré de pureté :99.66%Couleur et forme :White PowderMasse moléculaire :379.92Lansoprazole-d4
CAS :<p>Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.</p>Formule :C16H14F3N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.39(R)-Nicardipine
CAS :<p>(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Formule :C26H29N3O6Couleur et forme :SolidMasse moléculaire :479.53Luciferase, firefly
CAS :<p>Luciferase, firefly is a reporter gene in cellular imaging studies to quantify target gene expression levels and measure intracellular ATP content,</p>Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/ACabotegravir sodium
CAS :<p>Cabotegravir sodium inhibits HIV integrase (IC50: 2.5 nM), metabolized by UGT1A1, with minimal ARV interaction.</p>Formule :C19H16F2N3NaO5Couleur et forme :SolidMasse moléculaire :427.34SDZ 220-581
CAS :<p>SDZ 220-581 is a potent, orally active and competitive antagonist of NMDA receptor(pKi : 7.7).</p>Formule :C16H17ClNO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.74Nateglinide D5
CAS :<p>Nateglinide D5 is a deuterium labeled Nateglinide.</p>Formule :C19H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.45TGN-073
CAS :<p>TGN-073 is an enhancer of aquaporin 4 (AQP4), a water channel in astrocytes. It shows an increase in lymphatic transport in the rat brain by up to 41%.</p>Formule :C18H16N2O3SCouleur et forme :SolidMasse moléculaire :340.39617β-Estradiol sulfate sodium
CAS :<p>17β-Estradiol sulfate sodium (17β-Estradiol 3-sulfate sodium) is a neuroactive estrogen with vasoprotective properties that inhibits the growth of Neisseria brasiliensis and disrupts aquatic ecosystems.</p>Formule :C18H23NaO5SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :374.43SKA-121
CAS :<p>SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively).</p>Formule :C12H10N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :198.22Mexiletine-d6 hydrochloride
CAS :<p>Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.</p>Formule :C11H18ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.76N-Methyl-DL-aspartic acid
CAS :<p>N-Methyl-DL-aspartic acid, a glutamate analogue and NMDA receptor agonist, is utilized in neurological disease research.</p>Formule :C5H9NO4Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :147.13UBP608
CAS :<p>UBP608 selectively inhibits NMDA GluN1/GluN2A receptors, 23x more than GluN1/GluN2D.</p>Formule :C10H5BrO4Couleur et forme :SolidMasse moléculaire :269.05YM-244769
CAS :<p>YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)</p>Formule :C26H22FN3O3Degré de pureté :95.62%Couleur et forme :SolidMasse moléculaire :443.473,3-Diethylthiacarbocyanine iodide
CAS :<p>3, 3-diethylthiacarbocyanine iodide is a cyanine dye. Can be used for photochemical methods.</p>Formule :C21H21IN2S2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :492.44Eperisone hydrochloride
CAS :<p>Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone.</p>Formule :C17H26ClNODegré de pureté :99.80%Couleur et forme :White Or Similar To White Crystalline Powder With Peculiar Smell And Bitter TasteMasse moléculaire :295.85Evifacotrep
CAS :<p>Evifacotrep: TRPC5 antagonist for neurological disease research (WO2020061162, compound 100).</p>Formule :C18H12ClF4N5O2Degré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :441.77YHO-13177
CAS :<p>YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells.</p>Formule :C20H22N2O3SDegré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :370.47HC-030031
CAS :<p>HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2 and 5.3 μM, respectively.</p>Formule :C18H21N5O3Degré de pureté :99.69% - ≥95%Couleur et forme :SolidMasse moléculaire :355.39CCTA-1523
CAS :<p>CCTA-1523 is an efflux function of ABCG2 inhibitor. CCTA-1523 selectively reverses ABCG2-mediated MDR in cancer cells.</p>Formule :C16H15Cl2NO3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :340.2VU0134992
CAS :<p>VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM</p>Formule :C20H31BrN2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :411.38Cis-ACBD
CAS :<p>Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) is a potent and selective N-methyl-D-aspartate receptor agonist.</p>Formule :C6H9NO4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :159.14Omecamtiv mecarbil
CAS :<p>Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic</p>Formule :C20H24FN5O3Degré de pureté :98% - 99.23%Couleur et forme :SolidMasse moléculaire :401.43Dotinurad
CAS :<p>Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).</p>Formule :C14H9Cl2NO4SDegré de pureté :97.43% - 98.04%Couleur et forme :SolidMasse moléculaire :358.2(S)-ATPO
CAS :<p>(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.</p>Formule :C11H19N2O7PDegré de pureté :98.37% - 99.41%Couleur et forme :SolidMasse moléculaire :322.25Procyclidine hydrochloride
CAS :<p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>Formule :C19H30ClNODegré de pureté :99.24% - 99.88%Couleur et forme :Crystals From Petroleum Ether White PowderMasse moléculaire :323.9DL-Menthol
CAS :<p>DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis.</p>Formule :C10H20ODegré de pureté :99.74%Couleur et forme :White Crystals /89-78-1/ Physical Description White Crystalline Solid With A Peppermint Odor And Taste (Ntp 1992)Masse moléculaire :156.27γ-Acetylenic GABA
CAS :<p>γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase.</p>Formule :C6H9NO2Couleur et forme :SolidMasse moléculaire :127.143Pikamilone
CAS :<p>Pikamilone (Picamilon) is an intelligent medicine.</p>Formule :C10H12N2O3Degré de pureté :99.38%Couleur et forme :White Crystalline PowderMasse moléculaire :208.21UBP551
CAS :<p>UBP551 is a potent and selective NMDA receptors modulator.</p>Formule :C11H8O4Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :204.18DAAO inhibitor-1
CAS :<p>DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor (IC50: 0.12 μM).</p>Formule :C7H5FN2ODegré de pureté :97.84%Couleur et forme :SolidMasse moléculaire :152.13Argireline
CAS :<p>Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.</p>Formule :C34H60N14O12SDegré de pureté :96.79% - 99.65%Couleur et forme :White PowderMasse moléculaire :888.99OAC3
CAS :<p>OAC3 (4-fluoro-N-(1H-indol-5-yl)benzamide) is an activator of octamer-bound transcription factor 4.</p>Formule :C15H11FN2ODegré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :254.26Myomodulin acetate(110570-93-9 free base)
<p>Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.</p>Formule :C38H71N11O10S2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :906.17Raxatrigine
CAS :<p>Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.</p>Formule :C18H19FN2O2Degré de pureté :98% - 99.43%Couleur et forme :SolidMasse moléculaire :314.35Mitiglinide calcium hydrate
CAS :<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Formule :C38H52CaN2O8Degré de pureté :98.97% - 99.96%Couleur et forme :White SolidMasse moléculaire :704.91HC067047 Hydrochloride(883031-03-6 free base)
CAS :<p>HC-067047 hydrochloride, a TRPV4 antagonist, selectively inhibits human, rat, and mouse currents with IC50s: 486 nM, 133 nM, and 17 nM.</p>Formule :C26H29ClF3N3O2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :507.98Ivacaftor
CAS :<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Formule :C24H28N2O3Degré de pureté :99% - 99.98%Couleur et forme :SolidMasse moléculaire :392.49NPPB
CAS :<p>NPPB is a chloride channel blocker with IC50 of 80 nM .</p>Formule :C16H16N2O4Degré de pureté :99.95%Couleur et forme :Light Yellow To Yellow SolidMasse moléculaire :300.31NBQX
CAS :<p>NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.</p>Formule :C12H8N4O6SDegré de pureté :97.66% - 99.42%Couleur et forme :SolidMasse moléculaire :336.286-Methylflavone
CAS :<p>6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.</p>Formule :C16H12O2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :236.27Ononetin
CAS :<p>Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).</p>Formule :C15H14O4Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :258.27Vonoprazan
CAS :<p>Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and</p>Formule :C17H16FN3O2SDegré de pureté :99.87% - 99.92%Couleur et forme :SolidMasse moléculaire :345.39TRPM8 antagonist WS-3
CAS :<p>TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).</p>Formule :C13H25NODegré de pureté :97.64%Couleur et forme :DrypowderMasse moléculaire :211.34SG-209
CAS :<p>SG 209 is an analog of nicorandil and acts as a K+ channel opener and nitrate-free coronary vasodilator.</p>Formule :C10H12N2O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :208.21AZ194
CAS :<p>CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.</p>Formule :C34H31F2N3O3Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :567.62ICA-121431
CAS :<p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>Formule :C23H19N3O3S2Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :449.55SAR7334 hydrochloride
CAS :<p>SAR7334 hydrochloride is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).</p>Formule :C21H24Cl3N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.79Selinexor (KPT-330)
CAS :<p>Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (exportin 1 or XPO1), with potential antineoplastic activity.</p>Formule :C17H11F6N7ODegré de pureté :98% - 99.97%Couleur et forme :SolidMasse moléculaire :443.31Flupirtine maleate
CAS :<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Formule :C15H17FN4O2·C4H4O4Degré de pureté :99.5% - 99.9%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :420.39Homo-VK-II-36
CAS :<p>Homo-VK-II-36 (Homo-V-II-36) is a carvedilol analogue that acts by inhibiting store- overload-induced calcium release through the RyR2 channel.</p>Formule :C27H28N2O5Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :460.527-Chlorokynurenic acid sodium salt
CAS :<p>7-CKA sodium salt: NMDA receptor antagonist, glycine B site (IC50: 0.56 μM), blocks glutamate reuptake (Ki: 0.59 μM).</p>Formule :C10H6ClNNaO3Couleur et forme :SolidMasse moléculaire :246.6α-Cyano-4-hydroxycinnamic acid
CAS :<p>α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate</p>Formule :C10H7NO3Degré de pureté :99.8% - 99.86%Couleur et forme :PowderMasse moléculaire :189.17Thonzonium Bromide
CAS :<p>Thonzonium bromide: antimicrobial surfactant, similar to Farnesol, blocks proton transport, inhibits bone loss (EC50=69 μM).</p>Formule :C32H55BrN4ODegré de pureté :98.48% - 99.94%Couleur et forme :SolidMasse moléculaire :591.71Linerixibat
CAS :<p>Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor. Linerixibat can lower glucose in an animal model of type 2 diabetes.</p>Formule :C28H38N2O7SDegré de pureté :98.5% - 99.98%Couleur et forme :SolidMasse moléculaire :546.68ML365
CAS :<p>ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).</p>Formule :C22H20N2O3Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :360.41Vanilloid receptor antagonist 1
CAS :<p>Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.</p>Formule :C18H15N3O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :305.33Zoniporide hydrochloride hydrate
CAS :<p>Zoniporide HCl hydrate: selective NHE-1 inhibitor with a 14 nM IC50.</p>Formule :C17H19ClN6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.83SB-366791
CAS :<p>SB-366791 is a new and selective cinnamide TRPV1 antagonist.</p>Formule :C16H14ClNO2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :287.74Optovin
CAS :<p>Optovin is a TRPA1 activator, which is reversibly photoactivated.</p>Formule :C15H13N3OS2Degré de pureté :99.47% - 99.67%Couleur et forme :SolidMasse moléculaire :315.41Guan-fu base A hydrochloride(1394-48-5 free base)
CAS :<p>Guanfu base A HCl, an antiarrhythmic from Aconitum coreanum, inhibits CYP2D6 in humans, monkeys, and dogs.</p>Formule :C24H32NO6ClDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :465.97Vocacapsaicin
CAS :<p>Vocacapsaicin (CA-008), a prodrug of Capsaicin and a first-in-class non-opioid TRPV1 agonist, offers significant and enduring pain relief.</p>Formule :C26H41N3O4Couleur et forme :SolidMasse moléculaire :459.631N-Me-aminopyrimidinone9
CAS :<p>N-Me-aminopyrimidinone9 is a sodium channel antagonist</p>Formule :C16H21N3OSDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :303.42SKA-31
CAS :<p>SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).</p>Formule :C11H8N2SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :200.26Efonidipine hydrochloride
CAS :<p>Efonidipine HCl (NZ-105) blocks T-type/L-type calcium channels; used in hypertension treatment.</p>Formule :C34H39ClN3O7PCouleur et forme :SolidMasse moléculaire :668.12Trofinetide
CAS :<p>Trofinetide (NNZ-2566) is a synthetic analog of the endogenous N-terminus tripeptide. It has been shown to be neuroprotective in animal models of brain injury.</p>Formule :C13H21N3O6Degré de pureté :98.70% - 99.50%Couleur et forme :SolidMasse moléculaire :315.32Nav1.8-IN-1
CAS :<p>Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8</p>Formule :C20H15ClF3N3O2Degré de pureté :97.59%Couleur et forme :SolidMasse moléculaire :421.86-(4-Methoxyphenyl)-3-pyridazinamine
CAS :<p>6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist</p>Formule :C11H11N3ODegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :201.22Tulrampator
CAS :<p>Tulrampator (S-47445) is an orally bioavailable positive AMPAR with antidepressant effects.</p>Formule :C20H17FN4O3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :380.37Acetoxyvalerensre
CAS :<p>Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.</p>Formule :C17H24O4Degré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :292.37Vonoprazan fumarate
CAS :<p>Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.</p>Formule :C17H16FN3O2S·C4H4O4Degré de pureté :99.16% - 99.98%Couleur et forme :SolidMasse moléculaire :461.46(R)-baclofen
CAS :<p>(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.</p>Formule :C10H12ClNO2Degré de pureté :97.20% - 98.94%Couleur et forme :SolidMasse moléculaire :213.66CL 218872
CAS :<p>CL 218872: selective α1 GABAA receptor agonist, anxiolytic, and anticonvulsant; Ki=130 nM for α1, less potent for α2-α6.</p>Formule :C13H9F3N4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :278.23Revaprazan
CAS :<p>Revaprazan: novel, K⁺-competitive acid blocker; reversibly halts gastric H⁺/K⁺-ATPase; rivals PPIs in acid reduction.</p>Formule :C22H23FN4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.44TGN-020
CAS :<p>TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.</p>Formule :C8H6N4OSDegré de pureté :99.54% - 99.99%Couleur et forme :SolidMasse moléculaire :206.22Ko 143
CAS :<p>Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP).</p>Formule :C26H35N3O5Degré de pureté :99.01% - 99.89%Couleur et forme :SolidMasse moléculaire :469.57
