Transporteur membranaire/Canal ionique
Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.
Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"
- ABC(3 produits)
- ATPase(93 produits)
- Récepteur de l'adiponectine(5 produits)
- CFTR(64 produits)
- Récepteur CGRP(51 produits)
- Canal calcique(493 produits)
- Canal chlorure(49 produits)
- Récepteur GABA(336 produits)
- Transporteur de monoamine(23 produits)
- Transporteur de monocarboxylate(17 produits)
- NKCC(2 produits)
- NPC1L1(3 produits)
- Cotransporteur Na-K-Cl(8 produits)
- OAT(27 produits)
- OCT(7 produits)
- P-gp(53 produits)
- Canal potassique(276 produits)
- Pompe à protons(39 produits)
- SGLT(30 produits)
- Canal sodique(202 produits)
- Canal TRP/TRPV(92 produits)
Affichez 13 plus de sous-catégories
2270 produits trouvés pour "Transporteur membranaire/Canal ionique"
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Lifastuzumab
CAS :<p>Sulfamethoxazole-NO (SMX-NO) is a SMX-NO derivative and is the primary immunogen for sulfonamide hypersensitivity reactions.</p>Degré de pureté :97% (SDS-PAGE); 99.5% (SEC-HPLC) - 97% (SDS-PAGE); 99.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaAHN-683
CAS :<p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>Formule :C42H32FN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :709.72Way 125971
CAS :<p>Way 125971 is a bioactive chemcial.</p>Formule :C22H28N4O5S2Couleur et forme :SolidMasse moléculaire :492.614-oxo-2-Nonenal
CAS :<p>4-Hydroxy Nonenal and 4-oxo-2-Nonenal are lipid peroxidation byproducts, signaling oxidative stress and possibly causing mutagenesis.</p>Formule :C9H14O2Couleur et forme :SolidMasse moléculaire :154.2096-Hydroxykynurenic acid
CAS :<p>6-Hydroxykynurenic acid (6-HKA), a kynurenic acid (KYNA) derivative isolated from Ginkgo leaves, functions as a low-affinity NMDAR antagonist with an IC50 of 59</p>Formule :C10H7NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :205.17ATP Synthesis-IN-2
<p>ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.</p>Couleur et forme :Odour SolidCHET3
CAS :<p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>Formule :C21H21N5O3SDegré de pureté :99.64% - >99.99%Couleur et forme :SoildMasse moléculaire :423.49SC 4453
CAS :<p>SC 4453 is a digoxin analog and a cardiac glycoside derivative.</p>Formule :C41H64N2O12Couleur et forme :SolidMasse moléculaire :776.965Chlorotoxin(linear)
<p>Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.</p>Formule :C158H256N52O48S11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4004.76GSK2332255B
CAS :<p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>Formule :C18H19ClFN3O3SCouleur et forme :SolidMasse moléculaire :411.88BeKm-1
CAS :<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formule :C174H261N51O52S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4091.65RuBi-GABA
CAS :<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formule :C42H39F6N5O2P2RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :922.8AQP4 (201-220) TFA
<p>AQP4 (201-220) TFA is an encephalitogenic epitope of AQP-4. This compound can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal abnormalities, and lesions at the grey/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Couleur et forme :Odour SolidRiluzole-13C,15N2
CAS :<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Formule :CC7H5F3OS15N2Couleur et forme :SolidMasse moléculaire :237.18TRPV1 activator-2
CAS :<p>TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].</p>Formule :C19H29NO3Couleur et forme :SolidMasse moléculaire :319.44Anticancer agent 108
<p>Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both</p>Formule :C18H9NO5S2Couleur et forme :SolidMasse moléculaire :383.4Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Couleur et forme :Odour SolidChlorotoxin TFA
<p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>Formule :C160H250F3N53O49S11Couleur et forme :SolidMasse moléculaire :4109.74GpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Couleur et forme :Odour SolidASG-5ME
<p>ASG-5ME is a drug-antibody coupling targeting SLC44A4 that shows anti-tumor activity in xenograft models and may be used to study pancreatic and gastric cancer.</p>Degré de pureté :98.1% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDa5-Tridecanol
CAS :<p>5-Tridecanol blocks ion flux in sodium channels.</p>Formule :C13H28ODegré de pureté :97.87%Couleur et forme :SolidMasse moléculaire :200.36Vanzacaftor
CAS :<p>Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.</p>Formule :C32H39N7O4SDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :617.76Solpecainol
CAS :<p>solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.</p>Formule :C18H23NO3Degré de pureté :99.71%Couleur et forme :SoildMasse moléculaire :301.38Ampullosporin A
CAS :<p>Ampullosporin A is a peptaibol-type polypeptide isolated from the fungus Sepedonium ampullosporum (HKI-0053), exhibiting neuromodulatory activity. It inhibits hyperactivity induced by the NMDA receptor antagonist MK-801 and ameliorates social behavior abnormalities caused by subchronic ketamine treatment. Ampullosporin A modulates glutamate receptor activity without affecting dopamine D1 and D2 receptors.</p>Formule :C77H127N19O19Couleur et forme :SolidMasse moléculaire :1622.95PtdIns-(1,2-dioctanoyl) (sodium salt)
CAS :<p>PtdIns phosphates, a minor membrane lipid fraction, are vital for cell signaling. Synthetic PtdIns-(1,2-dioctanoyl) has C8:0 fatty acids and high solubility.</p>Formule :C25H47NaO13PCouleur et forme :SolidMasse moléculaire :609.602Flufiprole
CAS :<p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>Formule :C16H10Cl2F6N4OSCouleur et forme :SolidMasse moléculaire :491.24(2R,3S,11bS)-Dihydrotetrabenazine
CAS :<p>(2R,3S,11bS)-Tetrabenazine impurity, VMAT inhibitor for movement disorders.</p>Formule :C19H29NO3Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :319.44Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Formule :C17H30ClN5O2SCouleur et forme :SolidMasse moléculaire :403.97Tertiapin LQ
<p>Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.</p>Formule :C106H179N33O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2428.03Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Couleur et forme :LiquidHomocarnosine TFA
<p>Homocarnosine TFA: brain-exclusive GABA-histidine dipeptide, neuronal, anticonvulsant, antioxidant, anti-inflammatory.</p>Formule :C12H17F3N4O5Couleur et forme :SolidMasse moléculaire :354.28Withasomniferolide B
CAS :<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formule :C28H36O4Couleur et forme :SolidMasse moléculaire :436.58GeX-2
CAS :<p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>Formule :C103H169N43O27Couleur et forme :SolidMasse moléculaire :2441.72Volixibat
CAS :<p>Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.</p>Formule :C38H51N3O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.95Albanin A
<p>Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.</p>Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.358Conantokin G TFA
<p>Conantokin G TFA, a 17-aa peptide, blocks NMDA receptors with 480 nM IC50 and is neuroprotective.</p>Formule :C90H139F3N26O46Couleur et forme :SolidMasse moléculaire :2378.21AR-C141990 hydrochloride
CAS :<p>AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.</p>Formule :C26H29ClN4O4SCouleur et forme :SolidMasse moléculaire :529.05CBP-1008
<p>CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.</p>Couleur et forme :Odour Solid(R)-IDHP
CAS :<p>(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.</p>Formule :C12H16O5Couleur et forme :SolidMasse moléculaire :240.252,4,6-Tri-tert-butylphenol
CAS :<p>2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.</p>Formule :C18H30ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :262.43Phe-Met-Arg-Phe, amide
CAS :<p>Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.</p>Formule :C29H42N8O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :598.76ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Formule :C19H15FN2ODegré de pureté :99.98% - 99.98%Couleur et forme :SoildMasse moléculaire :306.33Sinapine hydroxide
CAS :<p>Sinapine hydroxide from crucifer seeds has anti-inflammatory, anti-oxidant, anti-tumor properties, and inhibits AChE, aiding neurodegenerative research.</p>Formule :C16H25NO6Couleur et forme :SolidMasse moléculaire :327.377Guangxitoxin 1E
CAS :<p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>Formule :C178H248N44O45S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3948.61NSC265473
CAS :<p>NSC265473 is an ABCG2 substrate.</p>Formule :C21H35N3O4SCouleur et forme :SolidMasse moléculaire :425.58TP-050
CAS :<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Formule :C16H15ClF2N6OCouleur et forme :SolidMasse moléculaire :380.78Nitrazolam
CAS :<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formule :C17H13N5O2Couleur et forme :SolidMasse moléculaire :319.32Digoxigenin Monodigitoxoside
CAS :<p>Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.</p>Formule :C29H44O8Couleur et forme :SolidMasse moléculaire :520.66318β-Glycyrrhetyl-3-O-sulfate
CAS :<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Formule :C30H46O7SCouleur et forme :SolidMasse moléculaire :550.75Chlorotoxin
CAS :<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Formule :C158H249N53O47S11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3995.71
