Transporteur membranaire/Canal ionique
Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.
Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"
- ABC(3 produits)
- ATPase(93 produits)
- Récepteur de l'adiponectine(5 produits)
- CFTR(64 produits)
- Récepteur CGRP(51 produits)
- Canal calcique(493 produits)
- Canal chlorure(49 produits)
- Récepteur GABA(336 produits)
- Transporteur de monoamine(23 produits)
- Transporteur de monocarboxylate(17 produits)
- NKCC(2 produits)
- NPC1L1(3 produits)
- Cotransporteur Na-K-Cl(8 produits)
- OAT(27 produits)
- OCT(7 produits)
- P-gp(53 produits)
- Canal potassique(276 produits)
- Pompe à protons(39 produits)
- SGLT(30 produits)
- Canal sodique(202 produits)
- Canal TRP/TRPV(92 produits)
Affichez 13 plus de sous-catégories
2270 produits trouvés pour "Transporteur membranaire/Canal ionique"
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Phenibut
CAS :<p>Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).</p>Formule :C10H13NO2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :179.22γ-DGG acetate(6729-55-1 free base)
CAS :<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Formule :C9H16N2O7Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :264.23GET73
CAS :<p>GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5.</p>Formule :C13H16F3NO2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :275.27Etimizol
CAS :<p>Etimizol improves memory by aiding the consolidation stage, effective against amnesia from hypoxia or brain injury.</p>Formule :C9H14N4O2Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :210.23Oxybuprocaine hydrochloride
CAS :<p>Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.</p>Formule :C17H29ClN2O3Degré de pureté :>99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :344.88DCPIB
CAS :<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Formule :C22H28Cl2O4Degré de pureté :99.79% - 99.87%Couleur et forme :SolidMasse moléculaire :427.36Doxapram hydrochloride hydrate
CAS :<p>Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.</p>Formule :C24H33ClN2O3C24H30N2O2·ClH·H2ODegré de pureté :99.64% - >99.99%Couleur et forme :SolidMasse moléculaire :432.99Glimepiride
CAS :<p>Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.</p>Formule :C24H34N4O5SDegré de pureté :97.84% - 98.87%Couleur et forme :White Cyrstalline SolidMasse moléculaire :490.62Disopyramide
CAS :<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Formule :C21H29N3ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :339.473,4,5-Trimethoxycinnamic acid
CAS :<p>3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the</p>Formule :C12H14O5Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :238.24Butamben
CAS :<p>Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.</p>Formule :C11H15NO2Degré de pureté :99.43%Couleur et forme :Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Masse moléculaire :193.24Penicillin G sodium salt
CAS :<p>Penicillin G sodium(Benzylpenicillin sodium) salt is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a</p>Formule :C16H17N2NaO4SDegré de pureté :98.11%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :356.37Leptomycin A
CAS :<p>Leptomycin A from Streptomyces inhibits CRM1, reducing HIV-1 replication, less potent than Leptomycin B, blocks protein nuclear export.</p>Formule :C32H46O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :526.7EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Formule :C22H20F4N2O3Couleur et forme :SolidMasse moléculaire :436.4Cavα2δ-IN-1
CAS :<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formule :C18H27N5OCouleur et forme :SolidMasse moléculaire :329.448Nitrazolam
CAS :<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formule :C17H13N5O2Couleur et forme :SolidMasse moléculaire :319.32Elgodipine
CAS :<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Formule :C29H33FN2O6Degré de pureté :98.95% - 99.50%Couleur et forme :SolidMasse moléculaire :524.58GS-9191 PM
<p>GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.</p>Formule :C11H16N6ODegré de pureté :99.79%Couleur et forme :SoildMasse moléculaire :248.28TRPA1 Antagonist 3
CAS :<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Formule :C11H8ClN3Couleur et forme :SolidMasse moléculaire :217.66(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS :<p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>Formule :C6H11NO2Couleur et forme :SolidMasse moléculaire :129.16GsMTx4
CAS :<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formule :C185H273N49O45S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4095.84BeKm-1
CAS :<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formule :C174H261N51O52S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4091.65GeX-2
CAS :<p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>Formule :C103H169N43O27Couleur et forme :SolidMasse moléculaire :2441.72α,β-Methylene-ATP dilithium
CAS :<p>α,β-Methylene ATP dilithium, a phosphonic analog of ATP, serves as a ligand for P2X3 and P2X7 receptors.</p>Formule :C11H16Li2N5O12P3Couleur et forme :SolidMasse moléculaire :517.07GpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Couleur et forme :Odour SolidWAY-326766
CAS :<p>WAY-326766 increases ion transport through mutant CFTR and can be used to alter the lifespan of eukaryotes.WAY-326766 can be used to treat cystic fibrosis (CF).</p>Formule :C21H23N3O5Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :397.42AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Formule :C20H25BrN4Couleur et forme :SolidMasse moléculaire :401.34Anisatin
<p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>Formule :C15H20O8Couleur et forme :SolidMasse moléculaire :328.317Trans (2,3)-Dihydrotetrabenazine
CAS :<p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>Formule :C19H29NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.44LRRK2-IN-15
<p>LRRK2-IN-15 is an inhibitor of LRRK2. It exhibits an IC50 value of 5 nM in PBMC cells and 1.5 μM for BCRP. This compound is utilized in the research of Parkinson's disease.</p>Couleur et forme :Odour SolidTP-050
CAS :<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Formule :C16H15ClF2N6OCouleur et forme :SolidMasse moléculaire :380.78Albanin A
<p>Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.</p>Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.358Jingzhaotoxin-XII TFA
<p>Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.</p>Couleur et forme :Odour Solid3-Aminopropylphosphinic acid
CAS :<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formule :C3H10NO2PCouleur et forme :SolidMasse moléculaire :123.092Huwentoxin I
CAS :<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Formule :C161H246N48O44S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3750.36LY-466195
CAS :<p>LY-466195 is a competitive antagonist of GLUK5 receptor.</p>Formule :C16H24F2N2O4Couleur et forme :SolidMasse moléculaire :346.37Hyp9
CAS :<p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>Formule :C18H26O5Couleur et forme :SolidMasse moléculaire :322.40AChE/Aβ-IN-2
<p>AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.</p>Formule :C20H25ClN4Couleur et forme :SolidMasse moléculaire :356.89Chlorotoxin TFA
<p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>Formule :C160H250F3N53O49S11Couleur et forme :SolidMasse moléculaire :4109.74JAMI1001A
CAS :<p>JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.</p>Formule :C16H17F3N4O3SCouleur et forme :SolidMasse moléculaire :402.39SLC26A3-IN-2
CAS :<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Formule :C19H13ClN2O2SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :368.84Homocarnosine
CAS :<p>Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.</p>Formule :C10H16N4O3Couleur et forme :SolidMasse moléculaire :240.26Idactamab
CAS :<p>Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :146.2 kDaAnticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Formule :C22H24N4O2Couleur et forme :SolidMasse moléculaire :376.45Crofelemer
CAS :<p>Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.</p>Couleur et forme :Solid2,4,6-Tri-tert-butylphenol
CAS :<p>2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.</p>Formule :C18H30ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :262.43Bendroflumethiazide
CAS :<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Formule :C15H14F3N3O4S2Degré de pureté :98% - >99.99%Couleur et forme :Crystals From Dioxane SolidMasse moléculaire :421.41Levamlodipine besylate Hemipentahydrate
CAS :<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formule :C20H25ClN2O5·C6H6O3SH2OCouleur et forme :SolidMasse moléculaire :1224.18Analgesic/antidepressant agent-1
<p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>Formule :C22H25ClN2O2Couleur et forme :SolidMasse moléculaire :384.9Resolvin D2 methyl ester
CAS :<p>RvD2 is an anti-inflammatory lipid made from docosahexaenoic acid by 15- and 5-lipoxygenase. Its methyl ester may serve as a prodrug.</p>Formule :C23H34O5Couleur et forme :SolidMasse moléculaire :390.52
