Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
708 produits trouvés pour "Synthèse ADN/ARN"
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Gemcitabine
CAS :<p>Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Formule :C9H11F2N3O4Degré de pureté :98.66% - 99.67%Couleur et forme :SolidMasse moléculaire :263.2Foscarnet sodium
CAS :<p>Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.</p>Formule :CNa3O5PDegré de pureté :98.52%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :191.95Vitamin D2
CAS :<p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>Formule :C28H44ODegré de pureté :98.73% - 99.89%Couleur et forme :Prisms From Acetone 1998)Masse moléculaire :396.65Oxaliplatin
CAS :<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Formule :C8H14N2O4PtDegré de pureté :97% - 99.93%Couleur et forme :SolidMasse moléculaire :397.29RG7800
CAS :<p>RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.</p>Formule :C24H28N6ODegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :416.52Floxuridine
CAS :Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Formule :C9H11FN2O5Degré de pureté :98.92% - 99.96%Couleur et forme :SolidMasse moléculaire :246.19Metarrestin
CAS :<p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>Formule :C31H30N4ODegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :474.6Xanthopterin (hydrate)
CAS :<p>Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.</p>Formule :C6H7N5O3Degré de pureté :98.99% - 99.93%Couleur et forme :Yellow To Orange Crystalline PowderMasse moléculaire :197.15Adenine
CAS :<p>Adenine: a purine nucleobase vital for ATP, NAD, FAD production, and DNA/RNA synthesis.</p>Formule :C5H5N5Degré de pureté :99.39% - 99.95%Couleur et forme :SolidMasse moléculaire :135.13BMVC-8C3O
CAS :<p>BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.</p>Formule :C42H53I3N4O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :1042.61NMDI14
CAS :<p>NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).</p>Formule :C21H25N3O4SDegré de pureté :97.79% - 99.37%Couleur et forme :SolidMasse moléculaire :415.51Oxolinic acid
CAS :<p>Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.</p>Formule :C13H11NO5Degré de pureté :98.39% - 99.72%Couleur et forme :Crystals From Dimethylformamide White Crystalline PowderMasse moléculaire :261.23Famciclovir
CAS :<p>Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.</p>Formule :C14H19N5O4Degré de pureté :99.85%Couleur et forme :Off-White PowderMasse moléculaire :321.33MALAT1-IN-1
CAS :<p>MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.</p>Formule :C19H21N3O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :323.39Procaine hydrochloride
CAS :<p>Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.</p>Formule :C13H20N2O2·HClDegré de pureté :99.1% - 99.22%Couleur et forme :White Crystalline PowderMasse moléculaire :272.77Folic acid
CAS :<p>Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production new cells. Cost-effective and quality-assured.</p>Formule :C19H19N7O6Degré de pureté :99.19% - 99.27%Couleur et forme :Yellowish-Orange Crystals; Extremely Thin Platelets (Elongated @ 2 Ends) From Hot Water 482°FMasse moléculaire :441.40N-Dodecyl-β-D-maltoside
CAS :<p>N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the</p>Formule :C24H46O11Degré de pureté :99.7% - >99.99%Couleur et forme :White PowderMasse moléculaire :510.62Enrofloxacin
CAS :<p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>Formule :C19H22FN3O3Degré de pureté :99.43% - >99.99%Couleur et forme :Pale Yellow CrystalsMasse moléculaire :359.39JH-RE-06
CAS :<p>JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.</p>Formule :C20H16Cl3N3O4Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :468.72PZL-A
CAS :<p>PZL-A, PZL-A, an activator of mtDNA synthesis, restored the activity of POLγ mutant variant.</p>Formule :C19H17ClN4O2Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :368.82Cinoxacin
CAS :<p>Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.</p>Formule :C12H10N2O5Degré de pureté :99.62% - 99.98%Couleur et forme :SolidMasse moléculaire :262.22BAY-2402234
CAS :<p>BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.</p>Formule :C21H18ClF5N4O4Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :520.84Levofloxacin hydrate
CAS :<p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formule :C18H20FN3O4H2ODegré de pureté :98.26%Couleur et forme :Pale Yellow SolidMasse moléculaire :370.38Rifaximin
CAS :<p>Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.</p>Formule :C43H51N3O11Degré de pureté :99.18% - 99.40%Couleur et forme :Red-Orange Crystalline PowderMasse moléculaire :785.88DNA2 inhibitor C5
CAS :<p>DNA2 inhibitor C5 is a specific cancer sensitizer with an IC50 of 20 μM, targeting multiple DNA2 activities.</p>Formule :C10H6N2O5Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :234.16Carmofur
CAS :<p>Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.</p>Formule :C11H16FN3O3Degré de pureté :98.53% - 99.98%Couleur et forme :SolidMasse moléculaire :257.26TK216
CAS :<p>TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.</p>Formule :C19H15Cl2NO3Degré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :376.23PTC299
CAS :<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Formule :C25H20Cl2N2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :467.34Capecitabine
CAS :<p>Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.</p>Formule :C15H22FN3O6Degré de pureté :99.81% - >99.99%Couleur et forme :Less Solid Colourless SolidMasse moléculaire :359.35ART558
CAS :<p>ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).</p>Formule :C21H21F3N4O2Degré de pureté :99.18% - 99.67%Couleur et forme :SolidMasse moléculaire :418.41Procaine
CAS :<p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>Formule :C13H20N2O2Degré de pureté :99.57% - 99.73%Couleur et forme :Anhydrous Plates Tables From Ligroin Or Ether SolidMasse moléculaire :236.31Enoxacin
CAS :<p>Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.</p>Formule :C15H17FN4O3Degré de pureté :98.68% - 99.89%Couleur et forme :Off-White To Yellow CrystalsMasse moléculaire :320.32Fludarabine
CAS :<p>Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.</p>Formule :C10H12FN5O4Degré de pureté :99.65% - 99.89%Couleur et forme :White SolidMasse moléculaire :285.23DI-87
CAS :<p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>Formule :C23H30N6O3S2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :502.65Cytarabine
CAS :<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Formule :C9H13N3O5Degré de pureté :99.83% - 99.93%Couleur et forme :Fine Off-White Crystalline PowderMasse moléculaire :243.22Epirubicin hydrochloride
CAS :<p>Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.</p>Formule :C27H30ClNO11Degré de pureté :98.13% - 99.79%Couleur et forme :Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Masse moléculaire :579.98Novobiocin Sodium
CAS :<p>Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.</p>Formule :C31H35N2NaO11Degré de pureté :99% - 99.28%Couleur et forme :SolidMasse moléculaire :634.61Rifapentine
CAS :<p>Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.</p>Formule :C47H64N4O12Degré de pureté :95.74% - ≥98%Couleur et forme :SolidMasse moléculaire :877.03Phleomycin
CAS :<p>Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage.</p>Formule :C48H69N17O20S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1268.29Nedaplatin
CAS :<p>Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.</p>Formule :C2H8N2O3PtDegré de pureté :99.88% - >99.99%Couleur et forme :Straw Yellow PowderMasse moléculaire :303.17Dithranol
CAS :<p>Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially</p>Formule :C14H10O3Degré de pureté :93.49% - 99.33%Couleur et forme :Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingMasse moléculaire :226.235-Fluorouridine
CAS :<p>5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.</p>Formule :C9H11FN2O6Degré de pureté :99.76% - 99.85%Couleur et forme :White PowderMasse moléculaire :262.19Doxifluridine
CAS :<p>Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.</p>Formule :C9H11FN2O5Degré de pureté :99.47% - 99.86%Couleur et forme :White SolidMasse moléculaire :246.19Farudodstat
CAS :<p>Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH with antitumor activity. It has the potential to be a first-in-class candidate in AML.</p>Formule :C19H14F2N2O3Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :356.32Methotrexate
CAS :<p>Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.</p>Formule :C20H22N8O5Degré de pureté :96.84% - 99.91%Couleur et forme :Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisMasse moléculaire :454.44DHODH-IN-11
CAS :<p>DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.</p>Formule :C15H11N3O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :265.27Hydroxyurea
CAS :<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Formule :CH4N2O2Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :76.05Carboplatin
CAS :<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Formule :C6H12N2O4PtDegré de pureté :98% - 99.72%Couleur et forme :White Crystalline PowderMasse moléculaire :371.25Daunorubicin hydrochloride
CAS :<p>Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein</p>Formule :C27H29NO10·HClDegré de pureté :96.21% - 99.53%Couleur et forme :Cancer DrugMasse moléculaire :563.99Enoxacin hydrate
CAS :<p>Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.</p>Formule :C15H17FN4O3H2ODegré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :347.34Hycanthone
CAS :<p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>Formule :C20H24N2O2SDegré de pureté :98.78%Couleur et forme :Yellow-Orange Powder (Ntp 1992)Masse moléculaire :356.48EFdA-TP
CAS :<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Formule :C12H15FN5O12P3Couleur et forme :SolidMasse moléculaire :533.195DMT-dG(ib) Phosphoramidite
CAS :<p>DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.</p>Formule :C44H54N7O8PDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :839.9223-Oxa-OSW-1
CAS :<p>23-Oxa-OSW-1 (SBF-1), a derivative of OSW-1, serves as a potent inhibitor of the osterol-binding protein (OSBP) with demonstrated antitumor activity [1] [2].</p>Formule :C54H82O16Couleur et forme :SolidMasse moléculaire :987.22DNA Gyrase-IN-15
<p>DNA Gyrase-IN-15 (Compound 11) is an antibacterial agent that inhibits both DHPS and DNA gyrase, with IC50 values of 1.73 and 0.07 µM, respectively. It shows antimicrobial activity against Enterococcus faecium (MIC of 15.62 µg/mL), Acinetobacter baumannii, Enterobacter (MIC of 7.81 µg/mL), Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Additionally, DNA Gyrase-IN-15 exhibits antibiofilm activity against Enterococcus faecium.</p>Formule :C31H26N4O4S2Couleur et forme :SolidMasse moléculaire :582.693Anticancer agent 262
<p>Anticanceragent 262 (compound 3h) is a DNA-intercalating antineoplastic agent with an IC50 value of 5.7 µM against A549 cancer cells.</p>Formule :C26H31N3OCouleur et forme :SolidMasse moléculaire :401.544Tilatamig samrotecan
<p>Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.</p>Couleur et forme :Odour SolidDIZ-3
CAS :<p>DIZ-3: Selective G4 ligand, stabilizes structure, inhibits ALT cancer cell growth by inducing cell cycle arrest and apoptosis.</p>Formule :C46H44F2N8Couleur et forme :SolidMasse moléculaire :746.895'-O-DMT-rI
CAS :<p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>Formule :C31H30N4O7Couleur et forme :SolidMasse moléculaire :570.59RNA recruiter 2
<p>RNA recruiter 2 serves as a QSOX1mRNA ligand. This compound functions as a target RNA ligand (RIBOTAC's target RNA ligand) and aids in developing RIBOTAC RNA degraders with antitumor activity. Additionally, RNA recruiter 2 is utilized in the synthesis of F1-RIBOTAC.</p>Formule :C20H16FNO4SCouleur et forme :SolidMasse moléculaire :385.409Clofarabine-5'-triphosphate
CAS :<p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>Formule :C10H14ClFN5O12P3Couleur et forme :SolidMasse moléculaire :543.625'-O-DMT-PAC-dA
CAS :<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Formule :C39H37N5O7Couleur et forme :SolidMasse moléculaire :687.74LB80317
CAS :<p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>Formule :C10H14N5O5PCouleur et forme :SolidMasse moléculaire :315.22S-MGB-234
CAS :<p>S-MGB-234 treats AAT, effective against T. congolense and T. vivax, no cross-resistance or shared transport with diamidines.</p>Formule :C30H32N8O4Couleur et forme :SolidMasse moléculaire :568.638RNase L ligand 1
<p>RNase L ligand 1 (Compound F1-COOH) serves as a ligand for RNase L and is utilized in the synthesis of F1-RIBOTAC.</p>Formule :C21H21Cl2NO3Couleur et forme :SolidMasse moléculaire :406.302Deoxythymidine-5'-triphosphate sodium hydrate
<p>dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.</p>Formule :C10H17N2O14P3·xNa·xH2OCouleur et forme :SolidMasse moléculaire :C10H17N2O14P3.xNa.xH2ODNA31
CAS :<p>DNA31 is a potent RNA polymerase inhibitor.</p>Formule :C48H58N4O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :898.99KC12
<p>KC12 acts as an inhibitor of the FOXM1 transcription factor. In cancer cells of the MDA-MB-231 line, KC12 exhibits cytotoxicity with an IC50 of 6.13 µM.</p>Formule :C23H17F3N2O3SCouleur et forme :SolidMasse moléculaire :458.4537-TFA-ap-7-Deaza-ddG
CAS :<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Formule :C16H16F3N5O4Couleur et forme :SolidMasse moléculaire :399.33Phen-DC3 Trifluoromethanesulfonate
CAS :<p>Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.</p>Formule :C36H26F6N6O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :848.75m7GpppGmpG
CAS :<p>m7GpppGmpG, a trinucleotide 5′ cap analog, exhibits capping efficiencies of 86% for the RNAs obtained [1].</p>Formule :C32H43N15O25P4Couleur et forme :SolidMasse moléculaire :1161.66Nuclease S1
CAS :<p>Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.</p>Couleur et forme :SolidVotoplam HCl
CAS :<p>Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).</p>Formule :C21H26ClN9ODegré de pureté :99.02%Couleur et forme :SoildMasse moléculaire :455.94Cytarabine triphosphate
CAS :<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Formule :C9H16N3O14P3Couleur et forme :SolidMasse moléculaire :483.16FF-10502
CAS :<p>FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.</p>Formule :C9H12FN3O3SCouleur et forme :SolidMasse moléculaire :261.272'-(2-Nitrobenzyl)-ATP trisodium
<p>2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.</p>Formule :C17H18N6Na3O15P3Couleur et forme :SolidMasse moléculaire :707.973615'-O-TBDMS-dA
CAS :<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C16H27N5O3SiCouleur et forme :SolidMasse moléculaire :365.5095-Iminodaunorubicin
CAS :<p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>Formule :C27H30N2O9Couleur et forme :SolidMasse moléculaire :526.54RAD51-IN-3
CAS :<p>RAD51-IN-3 is a Rad51 inhibitor.</p>Formule :C31H41N5O5S2Couleur et forme :SolidMasse moléculaire :627.82Agrocin 84
CAS :<p>Agrocin 84 is a microbial metabolite that inhibits DNA and protein synthesis, as well as amino acid transport, in the susceptible and virulent Agrobacterium strain H-38-9.</p>Formule :C22H36N6O16P2Couleur et forme :SolidMasse moléculaire :702.499PRV-IN-1
<p>PRV-IN-1 (compound c14) demonstrates significant antiviral activity against pseudorabies virus (PRV) with an EC50 of 14 pM and a CC50 of 343.7 μM. It effectively inhibits the replication of PRV.</p>Formule :C20H28N4O3Couleur et forme :SolidMasse moléculaire :372.461TH1085
CAS :<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Formule :C17H21N3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :267.37m7Gpppm6AmpG
CAS :<p>m7Gpppm6AmpG, a trinucleotide mRNA 5’ cap analog, facilitates RNA synthesis in vitro [1].</p>Formule :C33H45N15O24P4Couleur et forme :SolidMasse moléculaire :1159.69NLS (PKKKRKV)
CAS :<p>NLS (PKKKRKV) peptide from SV40 big T antigen boosts nuclear entry for gene transfer studies.</p>Formule :C40H78N14O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :883.14m7GpppApG
CAS :<p>M7GpppApG is a trinucleotide mRNA 5' cap analog utilized for in vitro RNA synthesis [1].</p>Formule :C31H41N15O24P4Couleur et forme :SolidMasse moléculaire :1131.64Bisucaberin
CAS :<p>Bisucaberin: a siderophore with anticancer properties; inhibits L1210/1MC cells and enhances 1023 cell cytolysis.</p>Formule :C18H32N4O6Couleur et forme :SolidMasse moléculaire :400.476T-2513
CAS :<p>T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.</p>Formule :C25H27N3O5Couleur et forme :SolidMasse moléculaire :449.507WRN inhibitor 17
CAS :<p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>Formule :C33H34F4N4O6SCouleur et forme :SolidMasse moléculaire :690.71Orotidine 5′-monophosphate trisodium
CAS :<p>Orotidine 5'-monophosphate trisodium, a pyrimidine nucleotide, is synthesized through the de novo DNA synthesis pathway by various microorganisms, including M.</p>Formule :C10H10N2Na3O11PCouleur et forme :SolidMasse moléculaire :434.14Dezecapavir
CAS :<p>Dezecapavir (example 4) acts as an effective inhibitor of viral replication, exhibiting an EC50 value of 0.025 nM in MT2 cells with a CC50 greater than 0.5 μM.</p>Formule :C37H29ClF9N9O5SCouleur et forme :SolidMasse moléculaire :918.19Ac-dA Phosphoramidite
CAS :<p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Formule :C42H50N7O7PCouleur et forme :SolidMasse moléculaire :795.878SD49-7
CAS :<p>SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.</p>Formule :C18H14N2O3Degré de pureté :99.91%Couleur et forme :SoildMasse moléculaire :306.32Emicoron
CAS :Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.Formule :C52H58N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :831.05VPC-18005
CAS :<p>VPC-18005: a luciferase inhibitor that blocks ERG-induced transcription by binding ERG-ETS, hindering DNA attachment.</p>Formule :C15H17N3O3SDegré de pureté :99.95%Couleur et forme :SoildMasse moléculaire :319.38Thio-ITP
CAS :<p>Thio-ITP (6-Thioinosine 5'-triphosphate) inhibits RNA polymerases I & II with Ki of 40.9 & 38.0 μM.</p>Formule :C10H15N4O13P3SCouleur et forme :SolidMasse moléculaire :524.235'-O-TBDMS-dU
CAS :<p>5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.</p>Formule :C15H26N2O5SiCouleur et forme :SolidMasse moléculaire :342.467CTP Synthetase-IN-1 Ammonium salt
<p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>Formule :C20H22F3N7O3S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :529.565'-O-DMT-2'-O-TBDMS-Bz-rC
CAS :<p>5'-O-DMT-2'-O-TBDMS-Bz-rC, a modified nucleoside, is utilized in the synthesis of DNA or RNA.</p>Formule :C43H49N3O8SiCouleur et forme :SolidMasse moléculaire :763.95TAC
CAS :<p>TAC is a TERT (telomerase reverse transcriptase) activator, promotes telomere synthesis, reduces cellular senescence and inflammatory cytokines</p>Formule :C14H12ClF2NO2SDegré de pureté :99.20%Couleur et forme :SolidMasse moléculaire :331.77Vanoxonin
CAS :<p>Vanoxonin is a new thymidylate synthetase inhibitor.</p>Formule :C18H25N3O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.41UCK2 Inhibitor-3
CAS :<p>UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.</p>Formule :C19H13BrFN5O2SCouleur et forme :SolidMasse moléculaire :474.31Bromochloroacetonitrile
CAS :<p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>Formule :C2HBrClNCouleur et forme :SolidMasse moléculaire :154.39Ac-rC Phosphoramidite
CAS :<p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>Formule :C47H64N5O9PSiDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :902.1MRK-952
<p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>Formule :C20H20ClF3N6Couleur et forme :SolidMasse moléculaire :436.8615'-O-DMT-2'-O-TBDMS-Ac-rC
CAS :<p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C38H47N3O8SiCouleur et forme :SolidMasse moléculaire :701.892Uridine triphosphate 13C9,15N2 sodium
CAS :<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Formule :C9H1415N2NaO15P3Couleur et forme :SolidMasse moléculaire :517.04Guanosine triphosphate
CAS :<p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>Formule :C10H16N5O14P3Couleur et forme :SolidMasse moléculaire :523.18Remdesivir nucleoside monophosphate
CAS :<p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>Formule :C12H14N5O7PCouleur et forme :SolidMasse moléculaire :371.245-BrdUTP sodium salt
CAS :<p>5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.</p>Formule :C9H10BrN2Na4O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :634.97RNA splicing modulator 3
CAS :<p>RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].</p>Formule :C19H20N6OSCouleur et forme :SolidMasse moléculaire :380.478-NH2-ATP
CAS :<p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>Formule :C10H17N6O13P3Couleur et forme :SolidMasse moléculaire :522.203'-Deoxyuridine-5'-triphosphate trisodium
<p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>Formule :C9H12N2Na3O14P3Couleur et forme :SoildMasse moléculaire :534.08HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS :<p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>Formule :C57H62N8O10SCouleur et forme :SolidMasse moléculaire :1051.212'-OMe-Ac-C Phosphoramidite
CAS :<p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>Formule :C42H52N5O9PCouleur et forme :SolidMasse moléculaire :801.86CW-2
<p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>Formule :C43H42Cl2FN11O10PtCouleur et forme :SolidMasse moléculaire :1156.21251Demycarosyl-3D-β-D-digitoxosylmithramycin SK
CAS :<p>Demycarosyl-3D-β-D-digitoxosylmithramycin SK, an analog of Mithramycin, exhibits potent anti-tumor activity.</p>Formule :C50H72O23Couleur et forme :SolidMasse moléculaire :1041.09Bz-rC Phosphoramidite
CAS :<p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Formule :C52H66N5O9PSiCouleur et forme :SolidMasse moléculaire :964.185LIN28-IN-2
<p>LIN28-IN-2 (Compound Ln268) blocks the interaction between the zinc finger domain (ZKD) of Lin28 and RNA substrates, inhibiting both Lin28a and Lin28b. It also suppresses the proliferation of Lin28-positive cancer cells and the growth of 3D spheroids.</p>Formule :C9H7FN2O2SCouleur et forme :SolidMasse moléculaire :226.227Carbazole
CAS :<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>Formule :C12H9NDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :167.211Guanosine 5'-triphosphate trisodium salt hydrate
CAS :<p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>Formule :C10H18N5NaO15P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.185KWR137
<p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.105EFdA-TP tetraammonium
<p>EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.</p>Formule :C12H27N9O12P3Couleur et forme :SolidMasse moléculaire :601.31Ribonuclease T1
CAS :<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Couleur et forme :SolidTS-002902
<p>TS-002902 is a small molecule inhibitor of TUT4/7, exhibiting antiproliferative activity. It holds potential for use in cancer research.</p>Couleur et forme :Odour Solidcis-Lomibuvir
CAS :<p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>Formule :C25H35NO4SCouleur et forme :SolidMasse moléculaire :445.61RNA polymerase II-IN-2
<p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>Formule :C41H58N10O12SCouleur et forme :SolidMasse moléculaire :915.027-TFA-ap-7-Deaza-ddA
CAS :<p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>Formule :C16H16F3N5O3Couleur et forme :SolidMasse moléculaire :383.331AV-153
CAS :<p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>Formule :C14H19NNaO6Couleur et forme :SolidMasse moléculaire :320.2975'-O-DMT-N4-Bz-2'-F-dC
CAS :<p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>Formule :C37H34FN3O7Couleur et forme :SolidMasse moléculaire :651.683'Ome-m7GpppAmpG
CAS :<p>3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.</p>Formule :C33H45N15O24P4Couleur et forme :SolidMasse moléculaire :1159.697-Deazaxanthine
CAS :<p>7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.</p>Formule :C6H5N3O2Couleur et forme :SolidMasse moléculaire :151.12FR901463
CAS :<p>FR 901463 is a biochemical.</p>Formule :C27H42ClNO8Couleur et forme :SolidMasse moléculaire :544.08PINT-87aa TFA
PINT-87aa TFA, an 87-aa peptide from LINC-PINT, binds PAF1c, blocking oncogene transcription and glioblastoma growth.Formule :C396H628N140O115S13·C2HF3O2Masse moléculaire :9721.05DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS :<p>DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.</p>Formule :C47H54N5O8PCouleur et forme :SolidMasse moléculaire :847.932'-Deoxy-2'-fluoro-l-uridine
CAS :<p>2'-Deoxy-2'-fluoro-1-uridine: an L-nucleoside, inhibits RNA viruses by blocking viral RNA polymerase.</p>Formule :C9H11FN2O5Couleur et forme :SolidMasse moléculaire :246.19Maleuric acid
CAS :<p>Maleuric acid is an anti-mitotic agent for research and boosts growth and fertility in flora and fauna.</p>Formule :C5H6N2O4Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :158.11c-Fos-IN-1
<p>c-Fos-IN-1 (Compound P16) acts as a c-Jun inhibitor, effectively reducing the mRNA and protein levels of c-Fos. It also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. This compound demonstrates anticancer properties through the inhibition of the ERK/c-Fos/Jun pathway. c-Fos-IN-1 curbs the proliferation and migration of gastric cancer cells, with an IC50 of 2.31 μM for MGC-803 cells, causing cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells. Additionally, c-Fos-IN-1 hampers the growth of gastric cancer tumors.</p>Formule :C28H35NO3Couleur et forme :SolidMasse moléculaire :433.582Deoxythymidine-5'-triphosphate
CAS :<p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>Formule :C10H17N2O14P3Couleur et forme :SolidMasse moléculaire :482.1675'-O-DMT-N4-Ac-2'-F-dC
CAS :<p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C32H32FN3O7Couleur et forme :SolidMasse moléculaire :589.61Suricapavir
CAS :<p>Suricapavir is an effective viral replication inhibitor with antiviral activity.</p>Formule :C41H29ClF9N9O4SCouleur et forme :SolidMasse moléculaire :950.23SR15006
CAS :<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Formule :C16H20ClN3O4SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :385.87N6-Methyladenine
CAS :<p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>Formule :C6H7N5Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :149.15Diguanosine 5′-triphosphate
CAS :<p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>Formule :C20H27N10O18P3Couleur et forme :SolidMasse moléculaire :788.4095'-O-DMT-rU
CAS :<p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>Formule :C30H30N2O8Couleur et forme :SolidMasse moléculaire :546.575'-O-TBDMS-dG
CAS :<p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>Formule :C16H27N5O4SiCouleur et forme :SolidMasse moléculaire :381.50(+)-Glaucarubinone
<p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>Formule :C25H34O10Couleur et forme :SolidMasse moléculaire :494.537Clofarabine-5'-diphosphate trisodium
<p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>Formule :C10H10ClFN5Na3O9P2Couleur et forme :SolidMasse moléculaire :529.58Cy5-dATP
<p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>Formule :C47H58N7O19P3S2Couleur et forme :SolidMasse moléculaire :1182.055'-O-TBDMS-N2-ibu-dG
CAS :<p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>Formule :C20H33N5O5SiCouleur et forme :SolidMasse moléculaire :451.59Pyrindamycin A
CAS :<p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>Formule :C26H26ClN3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :543.95Mulnitorsen
CAS :<p>Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].</p>Formule :C172H217N74O82P17S17Couleur et forme :SolidMasse moléculaire :5704.66YL-5092
<p>YL-5092 is an inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). It inhibits acute myeloid leukemia cells with an IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor activity in xenograft mice models using MOLM-13 or U937 cells.</p>Formule :C22H14F3N3O2SCouleur et forme :SolidMasse moléculaire :441.435'-O-DMT-N2-DMF-dG
CAS :<p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>Formule :C34H36N6O6Couleur et forme :SolidMasse moléculaire :624.698N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS :<p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>Formule :C21H35N12O17P3Couleur et forme :SolidMasse moléculaire :820.49(S)-DI-87
CAS :<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Formule :C23H30N6O3S2Degré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :502.65wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Couleur et forme :Odour SolidIBU-DC Phosphoramidite
CAS :<p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>Formule :C43H54N5O8PCouleur et forme :SolidMasse moléculaire :799.9062'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS :<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Formule :C10H14N5Na2O8PCouleur et forme :SolidMasse moléculaire :409.202ddGTP trisodium
<p>ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.</p>Formule :C10H13N5Na3O12P3Couleur et forme :SolidMasse moléculaire :557.13TS-002266
CAS :<p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>Formule :C31H32Cl2N6O5Degré de pureté :98.18%Couleur et forme :SoildMasse moléculaire :639.53R-1479
CAS :<p>R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.</p>Formule :C9H12N6O5Degré de pureté :98.11% - 99.95%Couleur et forme :SolidMasse moléculaire :284.2312R-LOX-IN-2
CAS :<p>12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.</p>Formule :C19H13NODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :271.31Vasoactive intestinal contractor
CAS :<p>Vasoactive intestinal contractor, a novel member of the endothelin family, stimulates a rapid increase in intracellular Ca2+ concentration in fura-2-overexpressed Swiss 3T3 cells [1.</p>Formule :C116H161N27O32S4Couleur et forme :SolidMasse moléculaire :2573.945'-O-TBDMS-Bz-dA
CAS :<p>5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.</p>Formule :C23H31N5O4SiCouleur et forme :SolidMasse moléculaire :469.617m7GpppAmpG
CAS :<p>M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].</p>Formule :C32H43N15O24P4Couleur et forme :SolidMasse moléculaire :1145.66Antipain
CAS :<p>Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.</p>Formule :C27H44N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.713Clofarabine-5'-diphosphate
CAS :Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.Formule :C10H13ClFN5O9P2Couleur et forme :SolidMasse moléculaire :463.6413-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.23Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Formule :C21H25FN4O2Couleur et forme :SolidMasse moléculaire :384.45Thailanstatin C
CAS :<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Formule :C30H46ClNO9Couleur et forme :SolidMasse moléculaire :600.15DG1
<p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>Formule :C19H17N5O5SCouleur et forme :SolidMasse moléculaire :427.435-Methylcytidine 5′-triphosphate
CAS :<p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>Formule :C10H18N3O14P3Couleur et forme :SolidMasse moléculaire :497.18Garenoxacin
CAS :<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>Formule :C23H20F2N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.41BRP
BRP, a peptide related to BRINP2, exhibits anti-obesity activity through the activation of FOS. It triggers FOS activation in the central nervous system, and its effect is independent of leptin, GLP-1 receptor, and melanocortin 4 receptor.Couleur et forme :Odour SolidDitercalinium chloride
CAS :<p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>Formule :C46H50Cl2N6O2Couleur et forme :SolidMasse moléculaire :789.83HDAC-IN-85
<p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>Formule :C24H27FN4O5Couleur et forme :SolidMasse moléculaire :470.495-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS :<p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>Formule :C22H31N3O5SiCouleur et forme :SolidMasse moléculaire :445.58RNA binder 1
<p>RNA binder 1 (Compound 4b) is an RNA-binding agent capable of crossing the blood-brain barrier. It selectively binds to the G-quadruplex structure of the G4C2 repeat sequence RNA of the C9orf72 gene. This compound significantly reduces levels of the toxic polypeptides poly(GA) and poly(GP) in cells derived from amyotrophic lateral sclerosis (ALS) patients, while it has no significant impact on the antisense polypeptide poly(PR), demonstrating selectivity for sense RNA. RNA binder 1 is useful for studying ALS and frontotemporal dementia (FTD).</p>Formule :C22H20N10S2Couleur et forme :SolidMasse moléculaire :488.13138Nusinersen
CAS :<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Degré de pureté :98.62%Couleur et forme :SolidN1-Methylpseudouridine-5′-triphosphate tetralithium
<p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>Formule :C10H13Li4N2O15P3Couleur et forme :SolidMasse moléculaire :521.9Carboxy-pyridostatin
CAS :<p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>Formule :C35H34N10O7Couleur et forme :SolidMasse moléculaire :706.715'-O-DMT-ibu-dC
CAS :<p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>Formule :C34H37N3O7Couleur et forme :SolidMasse moléculaire :599.67ML-60218
CAS :<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Formule :C19H15Cl2N3O2S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :452.3816,16-dimethyl Prostaglandin A1
CAS :<p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>Formule :C22H36O4Couleur et forme :SolidMasse moléculaire :364.526Chrexanthomycin C
<p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>Formule :C31H24O15Couleur et forme :SolidMasse moléculaire :636.51PAT-LM1
<p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>Couleur et forme :Odour Liquid5'-O-DMT-Bz-rC
CAS :<p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C37H35N3O8Couleur et forme :SolidMasse moléculaire :649.695-Methylcytidine 5′-triphosphate trisodium
<p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>Formule :C10H15N3Na3O14P3Couleur et forme :SolidMasse moléculaire :563.13M7G(3'-OMe-5')pppA(2'-OMe)
<p>M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.</p>Formule :C23H33N10O17P3Couleur et forme :SolidMasse moléculaire :814.49GS-443902 trisodium
CAS :<p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>Formule :C12H16N5O13P3·xNaCouleur et forme :SolidPOLRMT-IN-1
<p>POLRMT-IN-1 (compound S7) is an inhibitor of POLRMT, specifically utilized in cancer-related research.</p>Couleur et forme :Odour SolidCytidine 5'-diphosphate trisodium salt
CAS :<p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>Formule :C9H15N3Na3O11P2Degré de pureté :99.55%Couleur et forme :White Crystalline PowderMasse moléculaire :472.15Nitrosofolic acid
CAS :<p>Nitrosofolic acid is a folic acid derivaive.</p>Formule :C19H18N8O7Couleur et forme :SolidMasse moléculaire :470.40Carboxy pyridostatin trifluoroacetate salt
<p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>Formule :C37H35F3N10O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :820.73Xanthosine-5'-Triphosphate
CAS :<p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>Formule :C10H15N4O15P3Couleur et forme :SolidMasse moléculaire :524.164RNA splicing modulator 1
CAS :<p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>Formule :C19H20N6OSCouleur et forme :SolidMasse moléculaire :380.47Lorutengitide
CAS :<p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>Formule :C30H50N8O12Couleur et forme :SolidMasse moléculaire :714.764CSN5-IN-2
<p>CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.</p>Couleur et forme :Odour SolidPseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Formule :C27H23ClF2N4O2Couleur et forme :SolidMasse moléculaire :508.9472'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium
<p>2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium, an ATP analog, exhibits robust mixed-type inhibition of poly(AU) synthesis.</p>Formule :C10H11FLi4N5O12P3Couleur et forme :SolidMasse moléculaire :532.9
