Composés polycycliques

<p>Please enquire for more information about Methyl 1-(2-chloro-4-fluorobenzyl)-3-formyl-6-methoxy-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl indole-4-carboxylate is a synthetic compound that is a potent agonist for cytochrome P450 enzymes. It can be used to study the human cytochrome system, which is responsible for metabolizing drugs and other chemicals. Methyl indole-4-carboxylate has been shown to react with aldehydes, such as formaldehyde, leading to fluorescence. This compound also has the ability to bind to x-ray structures of human cytochrome p450. The addition of methyl indole-4-carboxylate to tissue culture cells leads to an increase in activity of tuberculosis by inhibiting the growth of Mycobacterium tuberculosis and Mycobacterium avium complex.</p>

<p>Please enquire for more information about 3,4-diaza-5-(tert-butyl)-2-hydroxy-3-((4-methylphenyl)sulfonyl)tricyclo[6.4.0.0&lt;2,6&gt;]dodeca-1(8),4,9,11-tetraen-7-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Iodoisatin is a heterocyclic compound that can be synthesized by cross-coupling reactions. It has been shown to inhibit the production of prostaglandin E2, COX-2 protein, and tumor necrosis factor in mouse macrophages. 4-Iodoisatin also inhibits the production of protein kinase C (PKC) in these cells. 4-Iodoisatin can be modified into a dimer form with many different substitutions on the ring structure and this modification increases its potency as an inhibitor of PKC. Irradiation can decompose the compound into a single isomer that is more potent than either of the two isomers. This drug may have therapeutic potential for treatment of cancer, arthritis, and other inflammatory disorders.</p>

<p>Isoquinoline-4-carbaldehyde is an aldehyde chemical that has been synthesized in the laboratory. It is a chiral molecule with one asymmetric carbonyl group. Isoquinoline-4-carbaldehyde is a potential precursor to naphthyridine, which can be used as a building block for the synthesis of natural products. Isoquinoline-4-carbaldehyde has been shown to have phosphine properties, and it can be used as a ligand in transition metal complexes. The molecule has been shown to exist in two forms, which coexist in equilibrium and can undergo interconversion.</p>

<p>Isoindoline is a compound that is used to treat bowel diseases. It is an inhibitor of jak1 and has been shown to be effective in the treatment of inflammatory bowel disease. The reaction mechanism of this drug is not fully understood, but it has been hypothesized that its activity may be due to inhibition of dpp-iv, which blocks the activation of T cells. Isoindoline was found to have low toxicity in h9c2 cells and redox potentials are expected to be low. This drug has also been shown to inhibit the synthesis of fatty acids by inhibiting the action of acyl-coenzyme A: diacylglycerol acyltransferase 2 (ACADS).</p>

<p>(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is a carbocyclic nucleoside that has been used as a flow rate standard to measure the rate of liquid chromatography. It is an organic solvent, which has been shown to have kinetic properties in the ring opening of lactams and the hydrolysis of esters. (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one can be synthesized by reacting with a cocatalyst and a reaction time of less than 5 minutes at room temperature in a high performance liquid chromatography method or by liquid chromatography with preparative methods.br&gt;br&gt;<br>(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is used as a binding agent for</p>

<p>3-Carboxy-5-(2-chlorophenyl)-1-phenylpyrazole is a white solid that is soluble in organic solvents. It is a useful scaffold that can be used as a starting material for the synthesis of complex compounds. 3-Carboxy-5-(2-chlorophenyl)-1-phenylpyrazole has been shown to be an intermediate in the synthesis of speciality chemicals and fine chemicals, such as pesticides and pharmaceuticals.</p>

<p>2,6-Diaminopurine hemisulfate salt is a fine chemical that can be used as a building block for research chemicals, reagents, and specialty chemicals. It has been shown to be useful in the synthesis of various types of complex compounds. 2,6-Diaminopurine hemisulfate salt is also versatile in the sense that it can be used as an intermediate in reactions or as a scaffold for chemical synthesis. This product has CAS number 69369-16-0.</p>

<p>Umbelliferone-3-carboxylic acid is a coumarin derivative, which is a type of natural or synthetic organic compound often utilized in biochemical research. It is sourced from modifications of natural coumarins, which are typically isolated from plants belonging to the Apiaceae family, such as parsley, celery, and carrots. This compound functions by interacting with cellular enzymes, providing a fluorescent probe that aids in the investigation of enzymatic activities and pathways.</p>

<p>Phosphodiesterase type 3 inhibitor; positive inotropic agent; vasodilatory</p>

<p>5-Methylindole-3-carboxaldehyde (5MI) is a β-unsaturated aldehydes that is used as an analyte in assays for the detection of α,β-unsaturated aldehydes. It has been shown to be effective in degranulation of cells and induces cellular degranulation. 5MI has also been shown to be an analog of other β-unsaturated aldehydes and acts competitively with these compounds.</p>

<p>Ethyl indole-3-acetate (EIA) is a compound that inhibits the growth of certain cancer cells. It belongs to the group of acyl halides. EIA inhibits the synthesis of nucleic acids, proteins and other macromolecules by the cancer cells. It has been shown to be effective in reducing the size of tumors in mice with prostate and breast cancer. This compound also inhibits enzymes such as abscisic acid oxidase, which is responsible for converting abscisic acid into reactive oxygen species. EIA has been shown to have hemolytic activity in human lung tissue, but not ovules or human erythrocytes. This may be due to its ability to inhibit hormone production and cause an increase in progesterone levels.</p>

<p>1,3-Diacetylindole is an alkene that belongs to the class of organic compounds. It can be prepared by Friedel-Crafts acylation of cyclopentenone with formaldehyde and hydrogen chloride gas. The molecule has a molecular electrostatic potential of -0.8 eV and a molecular weight of 126.1 g/mol. 1,3-Diacetylindole has been shown to react with Grignard reagent in an electrochemical study. Additionally, it has been used as a starting material for the synthesis of other molecules such as 2-methylquinoline and 1,2-dihydroquinoline. The vibrational and spectral data for 1,3-diacetylindole have been obtained using both experimental and computational methods. These data are useful for understanding the structure and reactivity of this compound at the molecular level.br&gt;br&gt; br&gt;br&gt;</p>

<p>Clioquinol is a topical corticosteroid that is used to treat skin disorders such as pemphigoid, psoriasis, and eczema. It is also used to treat the inflammation associated with acne. Clioquinol has been shown to be effective in treating bacterial infections of the skin by inhibiting the growth of bacteria. This drug also has anti-inflammatory properties and can be used for the treatment of various inflammatory skin conditions. Clioquinol is not absorbed through the skin and does not affect the blood's ability to clot.</p>

<p>Scopolin is a coumarin glucoside, which is derived from the plant secondary metabolism. It originates predominantly from species within the Solanaceae family, including tobacco and potato plants. Its biosynthesis involves the conversion of scopoline, a precursor molecule, through glucosylation. This process is catalyzed by glucosyltransferases, which facilitate the attachment of a glucose moiety.</p>

<p>5-Amino-1-phenylpyrazole-4-carboxamide (APC) is a synthetic compound that has been shown to have potential as an antitumor agent. This compound has been shown to inhibit the growth of cancer cells in vitro, with cytometric analysis showing that it inhibits DNA synthesis and cell proliferation. It also has antibacterial activity, which may be due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. APC has been found in wastewater at concentrations of 2.6 μg/L, indicating that it is currently being produced and used for industrial purposes. APC can be synthesized by reacting 1-(3-aminopropyl)piperazine with 3-(2H)-furanone and triethylamine to form 5-amino-1-[(2H)-pyridin-2-yl]pyrazole-4-- carboxylic acid chloride, which can then</p>

<p>4-Chloroindole-3-acetic acid is a plant hormone that belongs to the group of auxins. It has been shown to stimulate root formation in plants by increasing the amount of auxin present in the plant's tissues. 4-Chloroindole-3-acetic acid is an intramolecular hydrogen donor and can form hydrogen bonds with other molecules. It also has a receptor binding site and cyclic peptide backbone, which allow it to act as a transcription factor or enzyme inhibitor. This molecule has been shown to be an optimum concentration for root formation in physiology experiments, and can be used as a model system for auxin research.</p>

<p>4,4',6,6'-Tetramethyl-2,2'-bipyridine (TMTB) is a small molecule that can be used as an efficient and cost-effective catalyst for the production of hydrogen from water. TMTB is able to transform solar energy into chemical energy by converting light absorbed in a semiconductor material to an electric current. TMTB has been shown to improve the efficiency of solar cells by boosting the performance of the catalysts that drive chemical reactions in the devices. This effect was found to be synergistic with other materials such as graphene oxide and tungsten disulfide. In addition, TMTB nanoparticles were shown to have a normalizing effect on the charge density in photoelectrochemical cells, which may lead to improved stability and durability.</p>

<p>9-Hydroxyxanthene is a natural drug that has been used in traditional Chinese medicine for treating a variety of diseases. It is extracted from Rhizoma Gastrodiae and Angelicae Dahuricae. 9-Hydroxyxanthene has shown to be effective against various metabolic disorders, including insulin resistance, hyperlipidemia, and diabetes. The mechanism of action of 9-hydroxyxanthene is not known but it is thought to be due to its ability to activate the immune system by transferring reactions and promoting the production of antibodies. 9-hydroxyxanthene also shows anti-inflammatory effects by inhibiting the production of prostaglandins and leukotrienes. 9-hydroxyxanthene can also inhibit angiotensin II, which may reduce high blood pressure and congestive heart failure.</p>

<p>7-Ethylindole-3-glyoxylic acid ethyl ester is a versatile building block that can be used in the synthesis of complex compounds. It is a useful intermediate in the synthesis of pharmaceuticals, which can also be used as a reagent and speciality chemical. The compound has been shown to have high quality and is a useful scaffold for the synthesis of new compounds.</p>

<p>7-Ethoxycoumarin is a fluorescent substrate used in biochemical research, which is derived synthetically. It undergoes biotransformation primarily via oxidative dealkylation, catalyzed by cytochrome P450 enzymes, resulting in the formation of 7-hydroxycoumarin. By monitoring the fluorescent 7-hydroxycoumarin, researchers can assess enzymatic activity and study metabolic pathways.</p>

<p>5-Methoxyindole is a chemical compound that is soluble in water. It has been shown to inhibit tumor growth and induce apoptosis, as well as inhibit the expression of glycogen synthase kinase-3. The structure of 5-methoxyindole was determined by NMR spectroscopy and FT-IR spectroscopy. The compound has been observed to exhibit fluorescence properties at a wavelength of 490 nm when it is excited with UV light. A copper complex of 5-methoxyindole was studied using molecular modeling and FT-IR spectroscopy, which revealed that it can undergo nucleophilic attack by hydrogen bond formation or an acid/base reaction to form a new hydrogen bond. This study also found that 5-methoxyindole is able to form hydrogen bonds with its neighboring molecules, which may contribute to its high solubility in water.</p>

<p>4-Hydroxycoumarin is a synthetic organic compound, which is a derivative of coumarin. This compound derives from a benzopyrone structure, specifically known as a precursor in the synthesis of various anticoagulant agents. Its mode of action involves the inhibition of the enzyme vitamin K epoxide reductase. This inhibition subsequently decreases the synthesis of active clotting factors II, VII, IX, and X by preventing the regeneration of reduced vitamin K.</p>

<p>Please enquire for more information about 4,4'-Dinitro-2,2'-bipyridine-N,N'-dioxide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5,7-Dimethoxycoumarin is a naturally occurring coumarin derivative, which is primarily sourced from various plant species, most notably those belonging to the Apiaceae and Rutaceae families. This compound is characterized by the presence of methoxy groups at the 5 and 7 positions on the coumarin core structure. These structural features contribute to its biological activity by influencing its interaction with various biomolecular targets.</p>

<p>Poncimarin is a citrus-derived flavor compound, which is extracted from the peels of citrus fruits. Its mode of action involves mimicking natural citrus flavors, providing authentic taste profiles through a combination of volatile compounds that resemble those found in fresh citrus. The primary application of Poncimarin lies in its utilization as a flavoring agent in the food and beverage industry. It is incorporated to enhance the sensory attributes of products like beverages, confectioneries, and baked goods, delivering a refreshing citrus note that is both recognizable and appealing. Poncimarin's efficacy is attributed to its ability to integrate seamlessly with the existing flavor matrices of these products, ensuring a balanced and natural sensory experience. Its use extends to applications requiring stable, long-lasting flavor profiles, contributing to product innovation and development within sensory science.</p>

<p>Isopimpinellin is a furanocoumarin compound, which is derived from the plant Angelica archangelica, commonly known as angelica. This compound is characterized by its intricate chemical structure that includes the fusion of a furan ring to a coumarin backbone. The source, Angelica archangelica, is a biennial plant found predominantly in temperate regions and is notable for its use in traditional herbal medicine.</p>

<p>7-Chloro-2H-pyrido[3,2-B]-1,4-oxazin-3(4H)-one is a chemical which is used as a reagent and building block in the synthesis of more complex compounds. It has been reported to be an intermediate for the production of pharmaceuticals and agrochemicals. The compound can also be used as an intermediate for the synthesis of other valuable chemicals such as pesticides and dyes. 7-Chloro-2H-pyrido[3,2-B]-1,4-oxazin-3(4H)-one has a CAS number of 205748-05-6.</p>

<p>3,7-Dimethyl-1-propargylxanthine is a cyclase inhibitor that has been shown to have pharmacological effects. It has been shown to be effective in vivo models of Parkinson's disease and has reduced locomotor activity. This drug also inhibits the production of adenosine and dopamine, leading to neuronal death. The 3,7-dimethyl-1-propargylxanthine shows high selectivity for adenosine A3 receptors and is an antagonist at these receptors. It prevents mitochondrial membrane potential from decreasing, which may be due to inhibition of the production of reactive oxygen species by mitochondria. 3,7-Dimethyl-1-propargylxanthine also inhibits platelet aggregation by blocking the activation of phospholipase C and enhances platelet aggregation by inhibiting phosphodiesterase activity.</p>

<p>1,1'-Bicyclo[1,1,1]pentane-1,3-dicarboxylic acid is a diacid that has been found to be effective in the synthesis of many organic compounds. It can be used as a building block for other molecules with different functional groups and is an excellent bioisostere for disulfides. The addition of 1,1'-bicyclo[1,1,1]pentane-1,3-dicarboxylic acid to a nucleophilic compound can be used to synthesize an ester. This molecule can also undergo cross-coupling reactions with halogens such as chlorine or bromine. The crystal x-ray diffraction pattern indicates that this molecule has a linear structure.</p>

<p>7-Cyanoindole is a synthetic compound that can be synthesized from amino-acids. The synthesis of 7-cyanoindole starts with the hydration of cyanamide, which yields cyanogen chloride. This reaction is followed by the dehydration of this molecule to produce 7-cyanoindole. The fluorescence properties and lifetimes are dependent on the hydration and dehydrations states. Synthetically, 7-cyanoindole is used as a fluorescent probe for amino acids in solution. This probe has been shown to bind to amino acids at acidic pHs and fluoresce brightly at wavelengths around 400 nm. Industrialized methods for synthesis include reacting cyanoacetylene with ammonia or methylamine in the presence of silicane or silicon dioxide as a catalyst. Reaction yield is dependent on the method used and ranges from 10% to 100%.</p>

<p>6-Amino-2-chloropurine (6AC) is a nucleoside analogue that inhibits the synthesis of DNA, RNA, and protein by inhibiting the activity of polymerase chain reaction. It has been used to study the molecular mechanisms of pandemic influenza A virus and HIV infection. 6AC has also been shown to be effective in treating solid tumours and metastatic colorectal cancer in mice. This drug is also used as a competitive inhibitor for measuring endonuclease activity in polymerase chain reactions. 6AC binds to the enzyme's active site and prevents it from cleaving the DNA strands during replication, resulting in incomplete replication of the viral genome.</p>

<p>8-Aminoquinoline is a fluorescent probe that is used to detect the presence of nitrite ions in biological samples. It is used in electron paramagnetic resonance (EPR) experiments and can be used as a chemical inhibitor of cytochrome P450 enzymes. 8-Aminoquinoline has been shown to have minimal toxicity in animal models. It has been shown to inhibit the growth of Leishmania, an organism that causes leishmaniasis, by arresting protein synthesis at the ribosome level. The drug interactions of 8-aminoquinoline have not been well studied, but it may be necessary for patients to avoid other drugs that are metabolized by cytochrome P450 enzymes when taking this agent.</p>

<p>5-Methylindole-3-acetic acid (5MI3A) is a molecule that has been shown to have antiproliferative properties in bladder cancer cells. 5MI3A binds to the receptor for GABA, which is an inhibitory neurotransmitter. It also inhibits the production of proinflammatory mediators and reactive oxygen species in cancer cells. 5MI3A has anticancer activity in prostate cancer cells and may act by inducing apoptosis and inhibiting cell proliferation. Consumption of 5MI3A may reduce the risk of cancer development by preventing DNA damage from carcinogens, suppressing inflammation, and regulating cell growth through its antagonistic properties.</p>

<p>2-Aminoacridone is a fluorescent dye.  The applications of 2-Aminoacridone are extensive in biochemical and analytical research. It is commonly employed in glycoprotein and glycoconjugate studies, leveraging its high sensitivity and specificity in detecting saccharide structures. Researchers utilize this dye in various assays, including high-performance liquid chromatography (HPLC) and electrophoresis, to analyze carbohydrate content and structure. Its role is critical in advancing our understanding of carbohydrate-related biological processes, such as cell signaling and disease pathogenesis, facilitating developments in both diagnostics and therapeutic strategies.</p>

<p>10-(2,5-Dihydroxyphenyl)-10H-9-oxa-10-phospha-phenanthrene-10-oxide is a synthetic compound that has an orange color and a molecular weight of 568. It is soluble in chloroform, ethanol, acetone, ether and benzene. The compound does not react with water or hydrochloric acid. It has been shown to have synergistic interactions with chloride and glycol ethers. 10-(2,5-Dihydroxyphenyl)-10H-9-oxa-10-phospha phenanthrene 10 oxide can be synthesized using a polymeric matrix as the reaction medium.</p>

<p>5-Hydroxy-3-methylindole (5HMI) is a metabolite of the drug tamoxifen, which is used for the treatment of breast cancer. It is also found in urine samples and has been shown to be reactive with cytochrome P450 2E1 (CYP2E1). 5HMI has been shown to inhibit the activity of CYP2E1 in humans, rats, and mice. 5HMI has also been shown to have anti-epileptic properties in epileptics. This active form is metabolized by adipose tissue or liver cells through oxidation and conjugation with glucuronic acid. The human liver cells show constitutive androstane receptor (CAR) activation, which may be due to its ability to act as an agonist or partial agonist.</p>

<p>5-Methylindole is a molecule that has been found to be active against Staphylococcus aureus. This drug interferes with the synthesis of glycogen, which is an important energy storage molecule in animals. 5-Methylindole inhibits glycogen synthase kinase 3 (GSK-3) activity and thereby reduces the production of proinflammatory cytokines. This drug has also been shown to have cardiac effects, such as tachycardia and arrhythmias in mice. The optical properties of 5-methylindole are characterized by fluorescence and absorbance spectra, as well as its chemical reactions. 5-Methylindole is detectable at concentrations of 10 µg/mL and reacts with aminoglycosides by forming an adduct that can be detected using chromatographic methods.</p>

<p>Radiosensitiser in hypoxic tumours</p>

<p>3,6-Diamino-9(10H)-acridone is a nucleophilic compound that is used as a catalyst in peptide synthesis. It can be used to selectively introduce an acridine group into a peptide or other organic molecule. 3,6-Diamino-9(10H)-acridone is an example of a hypervalent organometallic compound that has been shown to catalyze the iodocyclization of aromatic rings. It also has been shown to catalyze the substitution of electron-deficient alkenes with electrophiles.</p>

<p>Marmin is a natural bioactive compound, which is a type of limonoid. It is primarily sourced from citrus fruits, especially those belonging to the Rutaceae family, such as lemons and oranges. The compound exhibits a range of biological activities due to its multifaceted mode of action.</p>

<p>8-Hydroxy-2-quinolinecarbonitrile is an uncomplexed ligand that can be used for the synthesis of metal complexes. 8-Hydroxy-2-quinolinecarbonitrile is insoluble in most solvents, including water, and has a high melting point. This compound can be synthesized from acetonitrile and primary amines by condensing with formaldehyde. It is not possible to catalyze this reaction, as it does not undergo homolysis or heterolysis reactions. The uncomplexed ligand has been shown to bind to metal ions such as copper and silver. Its diffraction pattern was found to have a polynuclear nature with a number of diffraction peaks within the range of 5–9 Å.</p>

<p>Decursinol is a coumarin derivative, which is sourced from the roots of the plant Angelica gigas, commonly found in East Asia. The compound is recognized for its biochemical properties, specifically as a secondary metabolite in the umbelliferous family. Its mode of action involves the inhibition of key inflammatory pathways, notably through the suppression of pro-inflammatory cytokines and enzymes such as COX-2 and NF-κB. This molecular interaction effectively reduces inflammatory responses at the cellular level.</p>

<p>7-Methylxanthine is a purine alkaloid that is the primary metabolite of caffeine. It is structurally related to theobromine, which is found in chocolate. 7-Methylxanthine has been shown to have hypoglycemic effects and may be useful for the treatment of myopia. The optimum concentration of 7-methylxanthine for inhibiting carotenoid biosynthesis has been determined as 10 μM. It also inhibits axial elongation in cultured chick retinal cells by reducing carotenoid levels and increasing p-hydroxybenzoic acid levels in the retina. The analytical method for quantifying 7-methylxanthine relies on high performance liquid chromatography with ultraviolet detection (HPLC/UV).</p>

<p>L(+)-Amethopterin hydrate is an immunosuppressant that suppresses the immune system by inhibiting RNA synthesis. It is a structural analogue of folic acid and has been shown to be effective in treating autoimmune diseases, such as rheumatoid arthritis. L(+)-Amethopterin hydrate is a neutral compound that is soluble in water and microsomal membranes, making it more easily absorbed through the gut than other compounds of this class. It also has been shown to have no toxic effects on cardiac cells at therapeutic concentrations. These properties make L(+)-Amethopterin hydrate an attractive candidate for treating autoimmune diseases when other treatments have failed.</p>

<p>6-Benzyloxyindole-3-carboxaldehyde is a benzyl compound that is produced by the catalytic hydrogenolysis of benzyl alcohol. The debenzylation product of 6-benzyloxyindole-3-carboxaldehyde is known as benzene.</p>

<p>Please enquire for more information about Ethyl 6-Bromoindole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Isoimperatorin is a naturally occurring furanocoumarin, which is a phytochemical compound found in certain plants, particularly within the Apiaceae family, such as Angelica dahurica. It is extracted from these botanical sources through processes like solvent extraction. Isoimperatorin exhibits a diverse mode of action, including the inhibition of various enzymes and modulation of signaling pathways. It has demonstrated significant effects on cytochrome P450 enzymes, potentially influencing drug metabolism. Additionally, Isoimperatorin has shown antioxidant properties and the ability to interfere with cell proliferation and apoptosis mechanisms.</p>

<p>5-(5-Chloro-2-hydroxyphenyl)-1-phenylpyrazole is a useful intermediate for the synthesis of complex compounds. It is also used as a reagent and a speciality chemical in research. 5-(5-Chloro-2-hydroxyphenyl)-1-phenylpyrazole has a CAS number of 36124-03-5. This chemical is soluble in organic solvents such as benzene, chloroform, dichloromethane, tetrahydrofuran, and toluene.</p>

<p>Indole-2-carboxylic acid methyl ester is a carbazole that can be synthesized from indole and hydrogen chloride. It has been shown to inhibit the production of β-amyloid, an important factor in the pathogenesis of Alzheimer’s disease. Indole-2-carboxylic acid methyl ester has also been shown to have inhibitory effects on ion-exchange, melatonin synthesis, and yields of aziridines. The affinity of indole-2-carboxylic acid methyl ester for aldehydes was found to be very high. It is also able to cross the blood brain barrier into the brain and has been shown to be effective against pancreatic cancer cells in vitro.</p>

<p>8-Methyl-3,8-diazabicyclo[3.2.1]octane dihydrochloride is a high quality reagent that is used as an intermediate in the synthesis of complex compounds. This compound has been shown to be useful as a scaffold for the synthesis of new compounds and is also a versatile building block for reactions in organic chemistry. 8-Methyl-3,8-diazabicyclo[3.2.1]octane dihydrochloride is also used as a speciality chemical and research chemical in various fields such as pharmaceuticals, agrochemicals, and other industries.</p>

<p>Synthon for preparation of cholinergic receptor ligands; hypotensive</p>

<p>Pteryxin is an alkaloid derivative, which is a natural product isolated primarily from certain plant species within the Apiaceae family. As a complex organic compound, it exhibits a range of biochemical interactions at the molecular level. The mode of action for Pteryxin primarily involves its ability to interact with specific enzymatic pathways and receptors, facilitating or inhibiting particular physiological processes. This biochemical interaction underlies its potential pharmacological effects, which are these products' primary focus of study.</p>

<p>5-Ethylindole-3-acetic acid is a high quality chemical that is an intermediate in the synthesis of a variety of complex compounds. It is also a reagent for many reactions and can be used as a building block for more complex compounds. 5-Ethylindole-3-acetic acid has been shown to have antihistamine, analgesic, and antipyretic properties and is useful in treating allergic reactions.</p>

<p>2-Chloroquinoline is a compound that has antimicrobial properties. It acts by inhibiting bacterial RNA synthesis and protein synthesis. 2-Chloroquinoline has been shown to have toxicological effects in animal studies, including cancer. It also inhibits the activity of the cb2 receptor and the CCR5 receptor, which are involved in tumor growth. The molecular docking analysis for this compound is available, which can be found on PubChem.</p>

<p>5-Iodoindole is an organic compound that is used as a nematicide. It has been shown to have cytostatic effects on the growth of human pathogens, juveniles, and model systems. 5-Iodoindole inhibits the production of reactive amines and pyridine in vivo. It also inhibits glutamine metabolism by competitive inhibition at the glutamate dehydrogenase enzyme. 5-Iodoindole also has hemolytic activity and is able to induce transcriptomic changes in P. aeruginosa cells.</p>

<p>Dihydrofolate reductase (DHFR, 1.5.1.3) is a NADP+/NADPH-dependent oxidoreductase, that reduces dihydrofolate to tetrahydrofolate in the following reaction: dihydrofolate + NADPH + H+ ⇌ tetrahydrofolate + NADP+One unit of dihydrofolate reductase will convert 1.0 μmole of dihydrofolic acid into tetrahydrofolic acid in 1 minute at pH 7.5, 22°C and presence of NADPH.</p>

<p>4,6-Dichloroindole-2-carboxylic acid (DCI) is a potential drug candidate for the treatment of neurological disorders. DCI binds to glutamate receptors, which are involved in many neurological diseases. It has been shown to inhibit glutamate dehydrogenase and thus block the production of glutamate from glucose. DCI also prevents neuronal death caused by excessive levels of glutamate and inhibits the activation of N-methyl-D-aspartate (NMDA) receptors. This drug is currently being investigated as a therapy for inflammatory diseases such as multiple sclerosis and Alzheimer's disease. One study has shown that DCI may be useful for treating cerebellar granule cells in a model system. It has been found to inhibit glycogen synthase kinase 3, which is an enzyme involved in signaling pathways that regulate cell growth and survival.</p>

<p>Substrate for dealkylase.</p>

<p>4,4'-Dicyano-2,2'-bipyridine is a ligand that binds to molybdenum and has been used in the diagnosis of mitochondrial DNA. It has been shown to be an effective treatment for tropical diseases such as malaria. This drug binds to the molybdenum cofactor in the enzyme ribonucleotide reductase, thereby inhibiting the production of ATP. 4,4'-Dicyano-2,2'-bipyridine also reacts with formic acid and ruthenium to produce a redshifted product that can be detected by electron paramagnetic resonance spectroscopy.</p>

<p>Please enquire for more information about Methyl 3-formyl-6-methoxy-1-(4-methoxybenzyl)-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Nitroindole is a hybridization analog of the base cytosine that has been used in biological studies. It has been shown to be active against microglia cells, which are involved in the inflammatory response. 7-Nitroindole's mechanism of action is not well understood; it may react with hydrochloric acid in the stomach to form nitrosamines and chloride ions, or it may react with hydrogen chloride to produce an ethyl ester. It also reacts with ethyl esters in the presence of light to form a photochemical reaction that generates fluorescence. The mechanism is not yet fully understood.</p>

<p>Daphnetin dimethyl ether is a synthetic chemical compound, which is a derivative of the naturally occurring coumarin scaffold. It is primarily sourced through chemical synthesis rather than extraction from natural compounds, allowing for precise control over purity and structural modifications that are otherwise challenging to achieve through natural means.</p>

<p>Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium bis(hexafluorophosphate) is a fluorescent dye that can be used to measure oxygen concentration. It has been shown to inhibit the transfer of oxygen at low concentrations. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium bis(hexafluorophosphate) is used as a calibration standard for the measurement of oxygen concentration in liquids by fluorescence.</p>

<p>Pyridoxine-5'-phosphate is a cofactor of the enzyme pyridoxal kinase, which catalyzes the conversion of pyridoxine to pyridoxal. Pyridoxine-5'-phosphate is also an essential cofactor for the enzyme transketolase, which catalyzes the transfer of a sugar phosphate group from erythrose 4-phosphate to dihydroxyacetone phosphate. Pyridoxine-5'-phosphate is involved in many reactions in the body, including protein synthesis and metabolism. It is required for glucocorticoid receptor activation and transcriptional regulation. It may also play a role in growth factor-β1 production and its role in cell signaling pathways. The deficiency of this vitamin causes symptoms such as weakness, irritability, depression, apathy, memory loss, hallucinations or convulsions.</p>

<p>7-Fluoro-2-methyl-1H-indole is a chemical compound that can be used as a building block to synthesize other organic compounds. The compound is also useful as a reagent in reactions such as the conversion of nitrobenzene to aniline. 7-Fluoro-2-methyl-1H-indole is soluble in acetone, chloroform, and ether. It has CAS number 432025-24-6, which identifies it as a fine chemical with many uses.</p>

<p>(-)-Oxypeucedanin is a natural furanocoumarin, which is a type of organic compound. Furanocoumarins are derived from specific plants and are known for their complex structures and biological activities. (-)-Oxypeucedanin is sourced primarily from plants belonging to the Apiaceae family, such as Peucedanum species.</p>

<p>Fraxidin is a naturally occurring compound, specifically an O-methylated coumarin, which is derived from certain plant sources such as the fruits of the ash tree. It is primarily obtained through the processing of various plant materials within the Rutaceae family. The mode of action of Fraxidin involves the inhibition of oxidative damage due to its capacity to scavenge free radicals, thus leading to potential antioxidant properties in biological systems.</p>

<p>1-Phenanthrol is a naturally occurring phenanthrene derivative that is used in the treatment of cervical cancer. It has been shown to be effective in the chemiluminescence method using urine samples, which indicates that it may have an effect on the body's metabolism. 1-Phenanthrol has also been shown to inhibit the production of s-phenylmercapturic acid, which is a metabolite of aromatic amines. This inhibition may be due to its receptor binding properties as it binds to and activates the peroxisome proliferator-activated receptor alpha (PPARα) and PPARγ. 1-Phenanthrol also inhibits angiotensin II type 1 receptors and can cause vasorelaxation by reducing blood pressure.</p>

<p>Plant hormone; auxin; inducer of root development; used in plant rooting</p>

<p>2,2'-Bipyridine-5,5'-dicarboxylic acid is an algal metabolite that has been shown to have a glucose sensor function. It is synthesized by Chlorella and other green algae in response to light and high concentrations of glucose. This compound can be used as a linker for the immobilization of fluorescent probes or luminescent probes. It also has a catalytic subunit that can be used in oxidation reactions at low temperatures with chloride as the oxidant. 2,2'-Bipyridine-5,5'-dicarboxylic acid is chemically stable and does not react with chloride or ligands. It can also be used as an oxidation catalyst for reactions at high temperatures.</p>

<p>5-Methoxy-2-methylindole is an organic solvent that has been shown to have a wide range of bioactive properties. It is used in the production of acetylcholine, which is an important neurotransmitter. 5-Methoxy-2-methylindole also reacts with chloride ions, which may be an important factor when considering the life cycles and bioactive substances of this molecule. The reaction yield depends on the pH of the solution. 5-Methoxy-2-methylindole can undergo chlorination reactions to form polychlorinated derivatives, which are used as petrochemicals. This molecule also has retinoid properties and can act as a proton donor or acceptor depending on whether it is protonated or deprotonated.</p>

<p>Ticarcillin is a bactericidal antibiotic that is used to treat many types of infections caused by gram-positive bacteria, such as Streptococcus pneumoniae, Enterococcus faecalis and Enterococcus faecium. Ticarcillin has been shown to be effective against antibiotic-resistant strains of bacteria, including multidrug efflux pumps. This drug also has been shown to inhibit the growth of gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa. Ticarcillin is used in combination with clavulanic acid for the treatment of infections caused by beta-lactamase producing organisms. It is also used in wastewater treatment to inhibit the growth of gram-negative bacteria that are resistant to other antibiotics. Ticarcillin can interfere with other medications by inhibiting their metabolism through cytochrome P450 enzymes or through competition for protein binding sites.</p>

<p>2,6-Dichloropurine is a nitrogenous base that inhibits the activity of certain enzymes in the body. It has been shown to inhibit protease activity and nitro reductases, which are enzymes that metabolize nitrosamines. 2,6-Dichloropurine also inhibits the synthesis of epidermal growth factor (EGF) and adenosine A3 receptors in vivo. This drug has potent antitumor activity against various cancer cells and is used for the treatment of HIV infections. 2,6-Dichloropurine can be synthesized from 6-fluoro-3-indoxyl-beta-D-galactopyranoside with an intramolecular hydrogen atom.</p>

<p>4-Bromo-1H-indole-6-carbonitrile is a versatile building block that can be used in the synthesis of complex compounds and research chemicals. 4-Bromo-1H-indole-6-carbonitrile is a reagent in the production of speciality chemicals, and is also used as an intermediate to produce other compounds. This compound is useful as a starting material for the synthesis of pharmaceuticals, agrochemicals, and perfumes. It has been shown to be an effective scaffold for the construction of heterocycles.</p>

<p>2-Chloro-1-methylquinolinium tetrafluoroborate (2CQBF) is a synthetic compound that inhibits protein synthesis. It has been used as an analytical reagent for the determination of proteins, including those in urine samples. 2CQBF has been shown to be effective in the treatment of cancer and other diseases, such as lupus erythematosus, arthritis, and psoriasis.</p>

<p>2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine is a fine chemical that belongs to the group of versatile building blocks. It can be used as a reagent or as a speciality chemical in research and development. 2-(3,5-Dimethyl-1H-pyrazol-1-yl)quinolin-8-amine is also a useful scaffold for the synthesis of complex compounds and has been shown to be an effective inhibitor of protein tyrosine kinases.</p>

<p>8-Hydroxyquinoline-2-carboxylic acid is a 3-hydroxyanthranilic acid derivative that is often used as a biomarker of urine. The 8OHQA can be synthesized from 3-hydroxyanthranilic acid by the action of xanthine oxidase and hydrogen peroxide, and it has been shown to be an inhibitor of protein synthesis. This inhibition may be due to its ability to form hydrogen bonds with the hydroxyl group on the ribose side chain and its ability to coordinate with metals. 8OHQA has been shown to have anti-inflammatory effects in bladder cancer cells, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Pyridoxamine dihydrochloride is a dinucleotide phosphate that is used as an antimicrobial agent. It has been shown to be toxic to certain bacteria, such as Staphylococcus aureus and Bacillus subtilis. Pyridoxamine dihydrochloride also has been shown to have inhibitory effects on the growth of yeast and fungi. This compound binds to calcium in the body, which may account for its observed toxicity to organisms that use this element for cellular processes. Pyridoxamine dihydrochloride has also been shown to have effects on the kidney and heart.</p>