Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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Bisindolylmaleimide VIII acetate
CAS :<p>Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.</p>Formule :C26H26N4O4Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :458.51CMPD101
CAS :<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Formule :C24H21F3N6ODegré de pureté :99.01% - 99.04%Couleur et forme :SolidMasse moléculaire :466.46BNC105
CAS :<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Imatinib Mesylate
CAS :<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Formule :C29H31N7O·CH4SO3Degré de pureté :98% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71N-Desmethyltamoxifen hydrochloride
CAS :<p>N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.</p>Formule :C25H28ClNODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :393.95Xentuzumab
CAS :<p>Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.</p>Degré de pureté :95% - > 95%Couleur et forme :LiquidMasse moléculaire :143.7 kDaCol003
CAS :<p>Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).</p>Formule :C14H11NO4Degré de pureté :98.67% - 99.03%Couleur et forme :SolidMasse moléculaire :257.24ATN-161 trifluoroacetate salt
CAS :<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67Elarofiban TFA
CAS :<p>Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.</p>Formule :C26H34F6N4O8Degré de pureté :99.08%Couleur et forme :SoildMasse moléculaire :644.56Efalizumab
CAS :<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.77%Couleur et forme :LiquidMasse moléculaire :146.14 kDaA-3 hydrochloride
CAS :<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Degré de pureté :95.42%Couleur et forme :SoildZagotenemab
CAS :<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Degré de pureté :95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.3 kDaBOS-172722
CAS :<p>BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).</p>Formule :C24H30N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :446.55Tirbanibulin Mesylate
CAS :<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formule :C27H33N3O6SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :527.63NVS-PAK1-1
CAS :<p>NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).</p>Formule :C23H25ClF3N5ODegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :479.93GRP78-IN-3
CAS :<p>GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.</p>Formule :C17H18N4O2SDegré de pureté :99.11%Couleur et forme :SoildMasse moléculaire :342.42Akt3 degrader 1
CAS :<p>Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.</p>Formule :C53H72N8O4Degré de pureté :98.12% - 99.02%Couleur et forme :SolidMasse moléculaire :885.19ALK inhibitor 2
CAS :<p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>Formule :C23H28ClN7O3SDegré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :518.03AC 7739
CAS :<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Formule :C18H22ClNO4Degré de pureté :99.38% - 99.55%Couleur et forme :SoildMasse moléculaire :351.83Bersanlimab
CAS :<p>Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.22 kDaAbciximab
CAS :<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaLarazotide acetate
CAS :<p>Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.</p>Formule :C34H59N9O12Degré de pureté :95.53% - 99.425%Couleur et forme :SolidMasse moléculaire :785.89RWJ 50271
CAS :<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41Bosutinib
CAS :<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Talquetamab
CAS :<p>Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.</p>Couleur et forme :LiquidMasse moléculaire :144.59 kDaOrbofiban TFA
CAS :<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Formule :C19H24F3N5O6Degré de pureté :97.21% - 98.72%Couleur et forme :SolidMasse moléculaire :475.42Spiperone
CAS :<p>Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.</p>Formule :C23H26FN3O2Degré de pureté :99.34% - 99.91%Couleur et forme :SolidMasse moléculaire :395.47Arimoclomol maleate
CAS :<p>Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.</p>Formule :C18H24ClN3O7Degré de pureté :99.44% - 99.98%Couleur et forme :SolidMasse moléculaire :429.85Danicamtiv
CAS :<p>Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.</p>Formule :C16H20F3N5O4SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :435.42Otelixizumab
CAS :<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Degré de pureté :>95%Couleur et forme :LiquidDonanemab
CAS :<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Degré de pureté :95%Couleur et forme :LiquidGNE 2861
CAS :<p>GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.</p>Formule :C22H26N6O2Degré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :406.48Verubulin hydrochloride
CAS :<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Formule :C17H18ClN3ODegré de pureté :98.29% - 99.77%Couleur et forme :SolidMasse moléculaire :315.8Rifabutin
CAS :<p>Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.</p>Formule :C46H62N4O11Degré de pureté :98.87% - 99.7%Couleur et forme :Red-Violet Crystalline PowderMasse moléculaire :847Mitoxantrone dihydrochloride
CAS :<p>Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.</p>Formule :C22H30Cl2N4O6Degré de pureté :97.05% - >99.99%Couleur et forme :Blue-Black Solid From Water Ethanol SolidMasse moléculaire :517.4Nilotinib
CAS :<p>Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.</p>Formule :C28H22F3N7ODegré de pureté :99.89% - >99.99%Couleur et forme :Off-White SolidMasse moléculaire :529.52IPI-493
CAS :<p>IPI-493 is a bioactive chemical.</p>Formule :C28H39N3O8Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :545.62Mosunetuzumab
CAS :<p>Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.</p>Degré de pureté :SDS-PAGE:94.4%;SEC-HPLC:96.1%Couleur et forme :LiquidMasse moléculaire :146.27 kDaAdropin (34-76) (human, mouse, rat)
CAS :<p>Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.</p>Formule :C190H293N55O68S2Degré de pureté :94.23% - 99.95%Couleur et forme :SolidMasse moléculaire :4499.82Tilavonemab
CAS :<p>Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.</p>Degré de pureté :95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidCibisatamab
CAS :<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Degré de pureté :SDS-PAGE:99.1%;SEC-HPLC:96.5%Couleur et forme :LiquidMasse moléculaire :191.1 kDaEthoxyquin
CAS :<p>Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.</p>Formule :C14H19NODegré de pureté :97.15% - 98.73%Couleur et forme :Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Masse moléculaire :217.31IMAB027
CAS :<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Degré de pureté :97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidCC-99677
CAS :<p>CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.</p>Formule :C22H20ClN5O3SDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :469.94Dasatinib
CAS :<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01SGC-AAK1-1
CAS :<p>SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.</p>Formule :C21H25N5O3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :427.52Paprotrain
CAS :<p>Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.</p>Formule :C16H11N3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :245.28Tidutamab
CAS :<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Degré de pureté :97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Couleur et forme :LiquidVeltuzumab
CAS :<p>Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.</p>Degré de pureté :97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Couleur et forme :LiquidGlofitamab
CAS :<p>Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.</p>Degré de pureté :SDS-PAGE:98.2%;SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :170.37 kDaDelcasertib
CAS :<p>Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).</p>Formule :C120H199N45O34S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :2880.28Fluorofenidone
CAS :<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Formule :C12H10FNODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :203.21Tadocizumab
CAS :<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Degré de pureté :97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Couleur et forme :Liquid(+)-Blebbistatin
CAS :<p>(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.</p>Formule :C18H16N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :292.33Meclofenamic acid sodium
CAS :<p>Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.</p>Formule :C14H10Cl2NNaO2Degré de pureté :98% - 98.96%Couleur et forme :SolidMasse moléculaire :318.14ADH-1 trifluoroacetate
CAS :<p>ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.</p>Formule :C24H35F3N8O8S2Degré de pureté :90.08% - 99.17%Couleur et forme :SolidMasse moléculaire :684.71Pamidronate Disodium
CAS :<p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>Formule :C3H9NNa2O7P2Degré de pureté :99.86% - 99.93%Couleur et forme :White CrystalsMasse moléculaire :279.03Recilisib
CAS :<p>Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.</p>Formule :C16H13ClO4SDegré de pureté :98.85% - 98.96%Couleur et forme :SolidMasse moléculaire :336.792,3-Butanedione 2-Monoxime
CAS :<p>2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.</p>Formule :C4H7NO2Degré de pureté :98.62%Couleur et forme :Physical Description Cream-Colored Powder (Ntp 1992)Masse moléculaire :101.1Abituzumab
CAS :<p>Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.</p>Degré de pureté :>95%Couleur et forme :LiquidTINK-IN-1
CAS :<p>TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.</p>Formule :C24H24N4O3Degré de pureté :99.4%Couleur et forme :SoildMasse moléculaire :416.47Foralumab
CAS :<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Degré de pureté :96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Couleur et forme :LiquidDasatinib monohydrate
CAS :<p>Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.</p>Formule :C22H28ClN7O3SDegré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :506.03Tubulin inhibitor 6
CAS :<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85Vantictumab
CAS :<p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>Degré de pureté :99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Couleur et forme :LiquidDarifenacin hydrobromide
CAS :<p>Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.</p>Formule :C28H31BrN2O2Degré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :505.45CK-666
CAS :<p>CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.</p>Formule :C18H17FN2ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :296.347-Aminocephalosporanic acid
CAS :<p>7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.</p>Formule :C10H12N2O5SDegré de pureté :91.05%Couleur et forme :White Solid PowderMasse moléculaire :272.28DM4
CAS :<p>DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.</p>Formule :C38H54ClN3O10SDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :780.37Arg-Gly-Asp-Ser acetate
<p>Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.</p>Formule :C17H31N7O10Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :493.47LXH254
CAS :<p>LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.</p>Formule :C25H25F3N4O4Degré de pureté :98.3% - 99.92%Couleur et forme :SolidMasse moléculaire :502.49ALK inhibitor 1
CAS :<p>ALK inhibitor 1 is a selective ALK kinase inhibitor.</p>Formule :C23H28BrN7O3SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :562.48N-Desmethyl imatinib
CAS :<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Formule :C28H29N7ODegré de pureté :98.60%Couleur et forme :Off-White To Pale-Yellow SolidMasse moléculaire :479.58Lyn-IN-1
CAS :<p>Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and Lyn</p>Formule :C30H31F3N8ODegré de pureté :97% - 98.02%Couleur et forme :SolidMasse moléculaire :576.62Entasobulin
CAS :<p>Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.</p>Formule :C26H18ClN3O2Degré de pureté :98.40%Couleur et forme :SolidMasse moléculaire :439.89Vedolizumab
CAS :<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Degré de pureté :SDS-PAGE:98.4%;SEC-HPLC:99.1%Couleur et forme :LiquidMasse moléculaire :146.80 kDaAKE-72
CAS :<p>AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.</p>Formule :C30H29F3N6ODegré de pureté :98.3%Couleur et forme :SoildMasse moléculaire :546.59Mps1-IN-3
CAS :<p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>Formule :C26H31N7O4SDegré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :537.63Bepranemab
CAS :<p>Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.</p>Degré de pureté :99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Couleur et forme :LiquidAS1949490
CAS :<p>AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.</p>Formule :C20H18ClNO2SDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :371.88Fluocinolone (Acetonide)
CAS :<p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>Formule :C24H30F2O6Degré de pureté :99.29% - 99.82%Couleur et forme :Crystals From Acetone & Hexane SolidMasse moléculaire :452.49ATN-161 acetate
CAS :<p>ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.</p>Formule :C25H39N9O10SDegré de pureté :98.27%Couleur et forme :SoildMasse moléculaire :657.7Abrilumab
CAS :<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Degré de pureté :98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :LiquidTeplizumab
CAS :<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Degré de pureté :SDS-PAGE:95.8%;SEC-HPLC:99.7%Couleur et forme :LiquidMasse moléculaire :145.79 kDaDSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Couleur et forme :Odour SolidEudebeiolide B
CAS :<p>Eudebeiolide B, isolated from Salvia plebeia R.</p>Formule :C15H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.3Phomopsin A
CAS :<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Formule :C36H45ClN6O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :789.23MS21
CAS :<p>MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.</p>Formule :C58H79ClN12O6SCouleur et forme :SolidMasse moléculaire :1107.8611H-Benzo[a]carbazole
CAS :<p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>Formule :C16H11NDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :217.27MAL3-101
CAS :<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Formule :C54H66N4O10Couleur et forme :SolidMasse moléculaire :931.12DSPE-PEG5000-cRGD
<p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>Couleur et forme :Odour SolidTubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Formule :C17H13ClN6OSCouleur et forme :SolidMasse moléculaire :384.84HSDVHK-NH2
CAS :<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Formule :C30H48N12O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :720.78BCR-ABL-IN-3
CAS :<p>BCR-ABL-IN-3 irreversibly inhibits Bcr-Abl with <100 nM IC50, showing significant anti-cancer effects.</p>Formule :C20H17ClF2N4O3SCouleur et forme :SolidMasse moléculaire :466.89Combretastatin A-1 phosphate tetrasodium
CAS :<p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>Formule :C18H18Na4O12P2Couleur et forme :SolidMasse moléculaire :580.2420-O-Demethyl-AP3
CAS :<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Formule :C31H41ClN2O9Couleur et forme :SolidMasse moléculaire :621.12Gly-Arg-Gly-Asp-Ser
CAS :<p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>Formule :C17H30N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.47Akt/SKG Substrate Peptide
CAS :<p>substrate for Akt/PKB</p>Formule :C36H59N13O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :817.94Chaetominine
CAS :<p>Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.</p>Formule :C22H18N4O4Couleur et forme :SolidMasse moléculaire :402.40LDV FITC
CAS :<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Formule :C69H81N11O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1368.53gp96-II
<p>Gp96-II is a gp96-blocking peptide that antagonizes cytokine production induced by gp96-mediated LPS. This compound is useful for research into inflammatory diseases.</p>Formule :C200H353N59O53SCouleur et forme :SolidMasse moléculaire :4464.37ML 2-23
<p>ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].</p>Formule :C47H53BrCl2N10O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1052.86INY-03-041
<p>INY-03-041, a PROTAC pan-AKT degrader, targets AKT1/2/3 with IC50s: 2.0/6.8/3.5 nM; GDC-0068 + Lenalidomide fusion.</p>Formule :C44H56ClN7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :798.41LY 379196
<p>LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.</p>Formule :C30H34N4O5SCouleur et forme :SolidMasse moléculaire :562.68TNIK-IN-7
CAS :<p>TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cells</p>Formule :C23H22N4O2Degré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :386.45αVβ8-IN-1
CAS :<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Formule :C25H32ClN5O4Couleur et forme :SolidMasse moléculaire :502.01Mumefural
CAS :<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Formule :C12H12O9Couleur et forme :SolidMasse moléculaire :300.224,4'-Di-O-methylellagic acid
CAS :<p>4,4'-Di-O-methylellagic acid is a useful organic compound for research related to life sciences. The catalog number is T125016 and the CAS number is 3374-77-4.</p>Formule :C16H10O8Couleur et forme :SolidMasse moléculaire :330.248β-catenin-IN-37
CAS :<p>β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI.</p>Formule :C13H9N9OCouleur et forme :SolidMasse moléculaire :307.277SNIPER(ABL)-039
CAS :<p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>Formule :C54H68ClN11O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1114.77RA-PR058
<p>RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.</p>Formule :C11H15ClF3N3OCouleur et forme :SolidMasse moléculaire :297.7Zolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidMasse moléculaire :150 kDaProtein Kinase C (19-36)
CAS :<p>Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.</p>Formule :C93H159N35O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2151.48HA15-Biotin
CAS :<p>HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.</p>Formule :C37H45N7O5S3Couleur et forme :SolidMasse moléculaire :763.99KT D606
CAS :<p>KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.</p>Formule :C59H50N6O10Couleur et forme :SolidMasse moléculaire :1003.06Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS :<p>Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.</p>Formule :C56H110N22O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1315.61SNIPER(ABL)-058
CAS :<p>SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein</p>Formule :C62H75N11O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1150.39PDS-0330
CAS :<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Formule :C25H17N3O2SDegré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :423.49DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Couleur et forme :Odour SolidDSPE-PEG1000-iRGD
<p>DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.</p>Couleur et forme :Odour SolidSangivamycin
CAS :<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Formule :C12H15N5O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :309.28Ceratamine A
CAS :<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Formule :C17H16Br2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.14MS170
CAS :<p>MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.</p>Formule :C45H56ClN9O7Couleur et forme :SolidMasse moléculaire :870.452-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Formule :C12H24ClNO4Couleur et forme :SolidMasse moléculaire :281.78Gantofiban
CAS :<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Formule :C21H29N5O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.48Gamitrinib TPP
CAS :<p>Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.</p>Formule :C52H65N3O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :891.078Rotigaptide
CAS :<p>Rotigaptide, modulates Cx43 for gap junctions, counteracts uncoupling, and maintains communication under stress.</p>Formule :C28H39N7O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :617.65SNIPER(ABL)-050
<p>SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.</p>Formule :C68H84N12O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1213.47DSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Couleur et forme :Odour SolidKanosamine hydrochloride
CAS :<p>Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species.</p>Formule :C6H14ClNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :215.63Gamitrinib TPP hexafluorophosphate
CAS :<p>Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity that can be used to study cancer and viral infection.</p>Formule :C52H65F6N3O8P2Degré de pureté :98.52% - 98.52%Couleur et forme :SolidMasse moléculaire :1036.03Fibronectin CS1 Peptide
CAS :<p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>Formule :C38H64N8O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :872.96SNIPER(ABL)-020
<p>SNIPER(ABL)-020, a Dasatinib-Bestatin conjugate via linker, inhibits ABL and targets IAP, reducing BCR-ABL protein.</p>Formule :C44H59ClN10O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :923.52FRATide
CAS :<p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>Formule :C55H102N2O2Couleur et forme :SolidMasse moléculaire :823.433SQLE-IN-1
CAS :<p>SQLE-IN-1 is a SQLE inhibitor with antitumor activity that inhibits the proliferation of Huh7 and the protein expression of PI3K and AKT.</p>Formule :C24H21F2N5O2SDegré de pureté :99.89%Couleur et forme :SoildMasse moléculaire :481.52para-amino-Blebbistatin
CAS :<p>para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.</p>Formule :C18H17N3O2Couleur et forme :SolidMasse moléculaire :307.353187-1, N-WASP inhibitor
CAS :<p>Inhibits N-WASP by stabilizing its autoinhibited form, blocking PIP2-induced actin assembly (IC50 ~2 μM), not directly affecting actin polymerization.</p>Formule :C96H122N18O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1784.13Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Formule :C28H25N3O4SCouleur et forme :SolidMasse moléculaire :499.58Hypoglycemic agent 3
<p>Compound H26, a derivative of corosolic acid, functions as Hypoglycemic agent 3. It exhibits lipid-lowering and significant blood glucose-reducing properties, making it a potential hypoglycemic drug. Hypoglycemic agent 3 targets MCCC1 to mitigate insulin resistance, and may be useful in researching type 2 diabetes.</p>Formule :C32H51NO5Couleur et forme :SolidMasse moléculaire :529.751Box5 TFA
<p>Box5 TFA, a potent Wnt5a antagonist, impedes Wnt5a signaling, restricts Wnt5a-initiated Ca2+ release, and hampers cell migration, showing promise for melanoma</p>Formule :C32H51F3N6O15S2Couleur et forme :SolidMasse moléculaire :880.9KGP591
<p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>Formule :C24H21NO5Couleur et forme :SolidMasse moléculaire :403.43MK2-IN-5
CAS :<p>MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway and</p>Formule :C61H113N21O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1396.68AKTide-2T
CAS :<p>Peptide substrate for Akt/PKB</p>Formule :C74H114N28O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1715.87st-Ht31
CAS :<p>Ht-31 stearate: Blocks RII subunits of PKA & AKAP interaction in cells; cell-permeable.</p>Formule :C129H217N29O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2798.27PROTAC HSP90 degrader BP3
CAS :<p>PROTAC BP3 selectively degrades HSP90, inhibits breast cancer growth (DC50=0.99µM), CRBN-dependent.</p>Formule :C32H29ClN8O5Couleur et forme :SolidMasse moléculaire :641.08Chemerin-9 (149-157)
CAS :<p>Chemerin-9, a nonapeptide C-terminal fragment of chemerin, retains full protein's activity as a ChemR23 agonist.</p>Formule :C54H66N10O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1063.16Coronaridine
CAS :<p>Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.</p>Formule :C21H26N2O2Couleur et forme :SolidMasse moléculaire :338.451KIF2C-IN-1
<p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>Formule :C36H39ClN4O9SCouleur et forme :SolidMasse moléculaire :738.21263Tubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Formule :C22H25NO6Couleur et forme :SolidMasse moléculaire :399.44Jatrophone
CAS :<p>Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.</p>Formule :C20H24O3Couleur et forme :SolidMasse moléculaire :312.4T-808
CAS :<p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>Formule :C17H19FN4Couleur et forme :SolidMasse moléculaire :298.367-Epi-10-oxo-docetaxel
CAS :<p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.86Anti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Degré de pureté :98%Couleur et forme :Odour SolidDynaMin inhibitory peptide, myristoylated
CAS :<p>Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.</p>Formule :C61H107N19O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1330.64SIAIS178
CAS :<p>SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).</p>Formule :C50H62ClN11O6S2Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :1012.68Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Formule :C24H20FN3O3Couleur et forme :SolidMasse moléculaire :417.436-Epi-ophiobolin G
<p>6-Epi-ophiobolin G (MHO7) is a marine-derived fungal metabolite that serves as an orally active Akt inhibitor capable of crossing the blood-brain barrier. It effectively inhibits the proliferation of glioblastoma (GBM) cells and promotes apoptosis. 6-Epi-ophiobolin G (MHO7) is suitable for research in glioblastoma studies.</p>Formule :C24H32O2Couleur et forme :SolidMasse moléculaire :352.24023AD57
CAS :<p>AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.</p>Formule :C22H20F3N7ODegré de pureté :99.05%Couleur et forme :SoildMasse moléculaire :455.44PROTAC BCR-ABL Degrader-1
<p>PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and</p>Formule :C43H40N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :792.84PKC β pseudosubstrate
CAS :<p>Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).</p>Formule :C177H294N62O38S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3994.84(8R)-8-Hydroxyepoxyboetirane A
<p>(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.</p>Couleur et forme :Odour Solid7-Epi-docetaxel
CAS :<p>7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.</p>Formule :C43H53NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :807.88AB-3PRGD2
CAS :<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formule :C137H215IN30O45SCouleur et forme :SolidMasse moléculaire :3161.32Echistatin
CAS :<p>Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>Formule :C217H341N71O74S9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5417.1Myrtucommulone
CAS :<p>Myrtucommulone is an inhibitor of the chaperonin activity of HSP60, correlating to LRP130 and LONP aggregation.</p>Formule :C38H52O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.81Filanesib TFA
CAS :<p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>Formule :C22H23F5N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.5Aberrant tau degrader 2
CAS :<p>Aberrant tau degrader 2 (Compound 4-12) acts as a degrader of tau protein and serves as a target protein ligand for the synthesis of PROTAC degrader C004019.</p>Formule :C19H27N7O3SCouleur et forme :SolidMasse moléculaire :433.528PTA001_A4
<p>PTA001_A4 (Anti-CDH17/Cadherin-17 Antibody) is a humanized antibody targeting CDH17/Cadherin-17 with anti-tumor activity and inhibits tumor cell growth.</p>Degré de pureté :95.8% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.3% (SEC-HPLC)Couleur et forme :Odour LiquidPU-H71 HCl
CAS :<p>PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.</p>Formule :C18H22ClIN6O2SDegré de pureté :98.95%Couleur et forme :SoildMasse moléculaire :548.83DSPE-PEG3000-iRGD
<p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>Couleur et forme :Odour SolidAdhesamine diTFA
CAS :<p>Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.</p>Formule :C28H32Cl2F6N8O6S2Couleur et forme :SolidMasse moléculaire :825.63DPH
CAS :<p>DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.</p>Formule :C18H13FN4O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :336.32α2β1 Integrin Ligand Peptide
CAS :<p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>Formule :C14H22N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.35Chromeceptin
CAS :<p>Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.</p>Formule :C19H16F3N3ODegré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :359.35hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Formule :C22H24N4OCouleur et forme :SolidMasse moléculaire :360.45NMS-E973
CAS :<p>NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.</p>Formule :C22H22N4O7Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :454.43Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Formule :C25H41N11O8SCouleur et forme :SolidMasse moléculaire :655.727Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formule :C16H13ClN6SCouleur et forme :SolidMasse moléculaire :356.83JG-258
CAS :<p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>Formule :C20H22ClN3OS3Couleur et forme :SolidMasse moléculaire :452.06SNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Formule :C42H52F3N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :839.9Fuzapladib
CAS :<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Formule :C15H20F3N3O3SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :379.4α-Linolenic Acid (sodium salt)
CAS :<p>α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables.</p>Formule :C18H29NaO2Couleur et forme :SolidMasse moléculaire :300.41Phosphatidylserines (bovine)
CAS :<p>Phosphatidylserine: a natural phospholipid, 2-10% in mammals, CNS-rich, synthesized in ER, involved in cell signaling, apoptosis marker.</p>Formule :C42H78NO10P(foroleoyl)Couleur et forme :SolidMasse moléculaire :788.1MS15 TFA
<p>MS15 TFA is a potent, selective AKT PROTAC degrader, effectively inhibiting AKT1, AKT2, and AKT3 with IC50 values of 798 nM, 90 nM, and 544 nM, respectively [1</p>Formule :C66H80F3N11O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1228.47Vinflunine Tartrate
CAS :<p>Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.</p>Formule :C45H54F2N4O8·xC4H6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :967.02Myelin Basic Protein
CAS :<p>Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.</p>Formule :C60H103N21O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1390.59Mps1-IN-6
<p>Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].</p>Formule :C35H39N9O3Couleur et forme :SolidMasse moléculaire :633.74MPC-0767
CAS :<p>MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.</p>Formule :C26H36BrN7O9S2Couleur et forme :SolidMasse moléculaire :734.64PDI-IN-4
<p>PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.</p>Formule :C17H12F3NO2Couleur et forme :SolidMasse moléculaire :319.278Dihydrocephalomannine
CAS :<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Formule :C45H55NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :833.928Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.11GRGDSP
CAS :<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Formule :C22H37N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.58Anti-EMMPRIN/CD147 Antibody
<p>Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Couleur et forme :Odour Liquid10-Oxo Docetaxel
CAS :<p>10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.</p>Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.874SNIPER(ABL)-019
<p>SNIPER(ABL)-019, a compound that links Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, exhibiting a</p>Formule :C60H77ClN12O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1177.85Osemitamab (FUT8-KO)
<p>Osemitamab (FUT8-KO) is a monoclonal antibody targeting claudin-18.2, expressed in CHO cells with a knockout of the fucosyltransferase 8 gene (FUT8). The absence of fucose heightens the antibody's ADCC effect. When combined with Capecitabine and Oxaliplatin, it can be used for G/GEJ cancer research.</p>Couleur et forme :Odour LiquidFoxy-5
CAS :<p>Foxy-5 is a wnt5a peptide mimetic</p>Formule :C26H42N6O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :694.77AKT1-IN-9
<p>AKT1-IN-9 (4) is a selective inhibitor of the AKT1(E17K) mutation, exhibiting EC50 values of 9 nM in LAPC4-CR cells and 995 nM in SkBr3 cells.</p>Formule :C33H25FN6O4Couleur et forme :SolidMasse moléculaire :588.588Crosstide
CAS :<p>Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.</p>Formule :C48H77N17O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1164.23
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