Réactifs synthétiques

Stability Hygroscopic
Applications One of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both prostaglandins are biosynthesized from the same precursors and that PGF2 is the synthetic reduction product of PGE2. Phospholipase A2 (PLA2) is a key enzyme for biosynthesis of PGF2α. Oxytocic; abortifacient.
References Granstrom, S., et al.: J. Biol. Chem., 246, 5254 (1971), Kubota, Y., et al.: Eur. J. Pharmacol., 467, 191 (2003), Crowell, J., et al.: Toxicol. Sci., 82, 614 (20040,

Stability Moisture Sensitive
Applications Potassium Disulfate is used in the synthesis of novel composite superionic conductors. Also used in the catalytic conversion of diethyl tartrate into pyruvate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bukun, N. et al.: Solid State Ionics, 136, 279 (2000); Sugiyama, S. et al.: Bull. Chem. Soc., 65, 2083 (1992);

Applications Sclareolide is found in Salvia yosgadensis and is a close analog of sclareol, an antifungal diterpene.
References Topcu, G., et. al.: J. Nat. Prod., 59, 113 (1996); Jasinski, M., et. al.: Plant Cell, 13, 1095 (2001)

Applications OCTADECYLTRIETHOXYSILANE (cas# 7399-00-0) is a useful research chemical.

Stability No Data available
Applications An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream.A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells. GW 501516 has been found to enhance endurance in mice without any training.
References Oliver, W.R., et al.: Proc. Natl. Acad. Sci., USA, 98, 5306 (2001), Sznaidman, M.L., et al.: Bioorg. Med. Chem. Lett., 13, 1517 (2003), Wang, Y.X., et al.: Cell, 113, 159 (2003); Chem. and Eng. News, p. 9, May 8, 2017

Applications Anticholinergic.
References Umetzu, T., et al.: Eur. J. Pharmacol., 64, 69 (1980),

Applications Vaborbactam is a non-β-lactam β-lactamase inhibitor. While not effective as an antibiotic by itself, it restores potency to existing antibiotics by inhibiting the beta-lactamase enzymes that would otherwise degrade them. When combined with an appropriate antibiotic it can be used for the treatment of gram-negative bacterial.
References Hecker, S.J., et al.: Journal of Medicinal Chemistry, 58, 3682 (2015);

Applications SODIUM ARSENATE, HEPTAHYDRATE (cas# 10048-95-0) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Shows antiulcer activity in rats.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Uchida, M., et al.: Chem. Pharm. Bull., 33, 3775 (1985), Yamasaki, K., et al.: Eur. J. Pharmacol., 142, 23 (1987),

Applications COPPER(II) SULFATE (cas# 7758-98-7) is a useful research chemical.

Stability Hygroscopic, Light Sensitive, Temperature Sensitive
Applications An intermediate in the Maillard reaction of proteins with glucose, which is metabolised to 3-Deoxyfructose. An intermediate in the formation of pyrraline, which might contribute to a pathological effect, such as carcinogenesis.
References Kato, H. et al.: Agric. Biol. Chem., 51, 683 (1987), Hayase, F. et al.: J. Biol. Chem., 264, 3758 (1989), Kato, H. et al.: Biochimica et Biophysica Acta, 1035, 71 (1990)

Stability Hygroscopic
Applications A deuterated selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),

Applications Potassium Metabisulfite (2:1) is used as a chemical preservative.
References Kuang, Y.T., et. al.: J. Food Process. Pres., 39, 56 (2015)

Applications Silver Nitrate is an organometallic reagent used in the preparation of silver nanoparticles for the application of environmentally benign metal products. Dyes and metabolites.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Umadevi, M. et al.: J. Nat. Sci. Tech., 29, 317 (2013); Kim, F. et al.: J. Am. Chem. Soc., 124, 14316 (2002);

Applications Sodium Nitrite is a common chemical reagent with pharmaceutical applications. It has been used in the treatment of cyanide poisoning however no longer in conjuction with sodium thiosulfate due to anumber of unwanted side effects. Also used in the inhibition of bacterial growth in cured and processed meats, prolonging shelf-life.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Baskin, S. et al.: J. Clin Pharm. et al.: 32, 368 (1992); Milkowski, A. et al.: Nitric Oxide, 15, 110 (2010);

Applications Chiral derivative of 3-Hydroxyisobutyrate.
References Waldmann, H., et al.: Bioorg. Med. Chem., 2, 477 (1994), Vonstein, V., et al.: J. Bacteriol., 177, 4540 (1995),