Anneaux à 6 chaînons

<p>Applications 5-Amino-2-phenyl-3(2H)-pyridazinone (cas# 13589-77-0) is a useful research chemical.<br></p>

<p>Applications 4-Phenyl-3-buten-2-ol can be used as reagent/reactant for rhodium-catalyzed dynamic kinetic enantio-, chemo- and regioselective allylation of phenols/naphthols/hydroxypyridines with allylic carbonates. It can also be used in biological study for comparative study on quality of soy sauce produced from whole soybeans and defatted soybeans.<br>References Li, C., and Breit, B.: Chemistry- A European Journal, 22, 14655-14663 (2016); Li, X., et al.: Zhongguo Niangzao, 34, 22-26 (2015);<br></p>

<p>Applications 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one (cas# 569646-79-3) is a useful research chemical.<br></p>

<p>Applications 2-Ethylbenzofuran is used in the synthesis of benzofurans as potential antianginal agents. They are also used in the preparation of 2-arylpyridines that are used in the synthesis of complexes with physical properties.<br>References Goldenberg, C. et al.: Eur. j. Med. Chem., 12, 81 (1977); Baloch, M. et al.: Eur. J. Med. Chem., 2012, 4454 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.<br>References Bhat, S. et al.: J. Hetero. Chem., 52, 1253 (2015); Xu, R. et al.: J. Labelled. Comp. Radiopharm., 58, 308 (2015);<br></p>

<p>Applications 4-​Hydrazinobenzoic acid hydrochloride (cas# 24589-77-3) is a useful research chemical.<br></p>

<p>Applications A redox buffer that increases the folding rate of disulfide-containing proteins realative to traditional buffers such as glutathione and glutathione-disulfide. A useful synthetic intermediate for the preparation of novel antiinflammatory agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gough, J.D., et al.: JACS, 124 (15), 3885 (2002)<br></p>

<p>Applications Dibenzyl Phosphite is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.<br>References Maung, J. et al.: Bioorg. Med. Chem., 12, 4969 (2004);<br></p>

<p>Impurity Praziquantel USP Related Compound A<br>Applications 2-(Descyclohexylcarbonyl)-2-benzoyl Praziquantel is used in the synthesis of Praziquantel (P702095), anthelmintic, effective against flatworms. Praziquantel USP Related Compound A<br>References Liu, H. et al.: Chem. Biol. Drug Des., 79, 470 (2012);<br></p>

<p>Applications 2,3-Dimethylacetophenone is used in the preparation of molecules with in vitro anti-mycobacterial activities<br>References Jadhav, S., et al.: J. Heterocycl. Chem., 55, 2993-2900 (2018)<br></p>

<p>Applications 3,4-Dihydro-2H-benzo[b][1,4]oxazin-6-ol (cas# 26021-57-8) is a useful research chemical.<br></p>

<p>Applications N,N''-Bis(methylphenyl)-1,4-benzenediamine (cas# 27417-40-9) is a useful research chemical.<br></p>

<p>Applications 2,5-Diaminotoluene sulfate occurs as an intermediate during hair dye formulation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Burnett, C., et al.: Food Cos. Toxicol., 13, 353 (1975)<br></p>

<p>Applications Aminophenyltrimethoxysilane is a useful intermediate for the preparation of aromatic silanes as high thermal stability coupling agents.<br>References Pan, Y., et al.: Adv. Mat. Res., 690, 1483 (2013)<br></p>

<p>Applications 1-Phenyl-1-heptanone is a useful building block for organic synthesis.<br></p>

<p>Applications Benzo[a]pyrene-1,6-quinone is a metabolite of Benzopyrene (B205800) and is able to induce epidermal growth factor receptor (EGFR) cell signaling in human mammary epithelial cells. Also highly mutagenic and carcinogenic.<br>References Rodriguez-Fragoso, L., et al.: Toxicol. Appl. Pharm., 235, 321 (2009); Sen, S., et al.: Chem. Res. Toxicol., 25, 2117 (2012)<br></p>

<p>Applications 1,1-Cyclohexanediacetic Acid (cas# 4355-11-7) is a compound useful in organic synthesis.<br></p>

<p>Applications AABD-SH(=4-Acetamido-7-mercapto-2,1,3-benzoxadiazole)[for HPLC Labeling] (cas# 254973-02-9) is a useful research chemical.<br></p>

<p>Applications 1,1-Bis(4-hydroxyphenyl)-2-phenyl-1-butene (cas# 91221-46-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-Benzyl-2-thiouracil (cas# 6336-50-1) is a useful research chemical.<br></p>

<p>Applications 3-(Benzyloxy)-2,2-dimethyl-1-propanol is an protected intermediate of NPG Glycol (N897000), is used in the synthesis of tetraphenylporphyrins.<br>References Lindsey, J. et al.: J. Org. Chem., 52, 827 (1987); Evans, D. et al.: J. Am. Chem. Soc., 121, 7540 (1999);<br></p>

<p>Applications A metabolite of pyrethroid insecticides such as: Deltamethrin, Permethrin, Cypermethrin, Fenvalerate, Decamethrin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Woollen, B., et al.: Xenobiotica, 22, 983 (1992), Saito, K., et al.: Toxicol. Sci., 57, 54 (2000), Fang, H., et al.: Chem. Res. Toxicol., 14, 280 (2001), Andersen, H., et al.: Toxicol. Appl. Pharmacol., 179, 1 (2002),<br></p>

<p>Applications 5-(3-hydroxyphenyl)pentanoic acid (cas# 31129-95-0) is a useful research chemical.<br></p>

<p>Applications Dibenzofuran is a reagent in Friedel-Crafts acylation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Albrecht, W. L., et al.: J. Med. Chem., 20, 364 (1977);<br></p>

<p>Applications 6-(Aminocarbonyl)-3-cyclohexene-1-carboxylic Acid is a useful building block for organic synthesis.<br></p>

<p>Applications 4-octylbenzoic acid (cas# 3575-31-3) is a useful research chemical.<br></p>

<p>Applications 2-Hydroxybenzeneethanol can be used to synthesize cyclic products and organoaluminim oligomers. Inelastic electron tunnelling spectra of 2-hydroxyphenethyl alcohol adsorbed on thin-film aluminium and magnesium oxide has been investigated.<br>References Ziemkowska, W., et al.: Main Group Met. Chem., 21, 105, (1998); Brown, N., et al., Spectrochim. Acta A, 48, 939 (1992)<br></p>

<p>Applications 2-Butylbenzo[D]isothiazol-3(2H)-one (cas# 4299-07-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light Sensitive<br>Applications Methyl 2-Iodobenzoate is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist that is used as an antiasthmatic. Methyl 2-Iodobenzoate is also used as a reagent in the synthesis of isoquinolinone-based tricycles as polyribose polymerase-1 inhibitors.<br>References Bollikonda, S., et al.: J. Org. Chem., 80, 3891 (2015); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998); Chen, J., et al.: Bioorg. Med. Chem. Lett., 24, 2669 (2014)<br></p>

<p>Applications Benzylamine has been used as a reactant in the preparation of diacetylated benzylamide which has shown to induce a G1/G0 arrest in tumor cells and cytotoxicity against human ovarian cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Siewert, B., et. al.: Bioorg. Med. Chem., 22, 594 (2014)<br></p>

<p>Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.<br>References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)<br></p>

<p>Applications Diamino-5-phenylthiazole Hydrobromide is an phenylthiazole derivative used in the preparation of antiallergic and antiinflammatory agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);<br></p>

<p>Applications A metabolite of benzene.<br>References Aoyama, K., et al.: Toxicol. Appl. Pharmacol., 85, 92 (1986), Sutter, T., et al.: J. Biol. Chem., 269, 1309 (1994), Farris, G., et al.: Toxicology, 118, 137 (1997), Jason, J., et al.: J. Immunol. Methods, 207, 13 (1997), Lee, M., et al.: Immunology, 106, 496 (2002),<br></p>

<p>Applications 2-(Diphenylmethoxy)-N-ethylamine (cas# 17349-94-9) is a compound useful in organic synthesis.<br></p>

<p>Applications N-benzylcyclohexanamine (cas# 4383-25-9) is a useful research chemical.<br></p>

<p>Applications N-Undecylbenzenesulfonic Acid is an anionic surfactant.<br>References Mottaleb, M. A.: Anal. Sci., 15, 1137 (1999), Kolb, M., et al.: LaborPraxis, 22, 56 (1998); Ferrer D., et al.: Tenside, Surfact., Det., 34, 278 (1997)<br></p>

<p>Applications o-tert-Butyl-α-chlorotoluene is a useful research reagent for the competitive chloromethylation of alkylbenzenes.<br>References Takezawa, T., et al.: Nippon Kagaku Kaishi 6, 1047 (1989); Hu, Y. L., et al.: J. Chil. Chem. Soc., 55, 97 92 (2010); Pinnell, R. P., et al.: Tetrahedron Lett., 25, 3511 (1984)<br></p>

<p>Applications 1,3-Diethynylbenzene (cas# 1785-61-1) is a useful research chemical.<br></p>

<p>Applications 5-AMINO-2-HYDROXYBENZONITRILE (cas# 87029-84-3) is a useful research chemical.<br></p>

<p>Applications (1R,2R)-1,2-Cyclohexanedimethanol 1,2-Dimethanesulfonate (cas# 186204-35-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 2-Sulfamoylbenzoate is a building block used in various synthetic preparations. It is also classified as a pollutant found in a municipal wastewater treatment plant.<br>References Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009);<br></p>

<p>Applications Methyl 3-Hydroxybenzoate (cas# 19438-10-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,3-dihydroxypropyl 4-hydroxybenzoate (cas# 93778-15-5) is a useful research chemical.<br></p>

<p>Applications Amitraz (A633320) impurity, its degradation products in fruits.<br>References Hernando, M., et al.: Anal. Bioanal. Chem., 389, 1815 (2007), Pico, Y., et al.: Anal. Chem., 79, 9350 (2007),<br></p>

<p>Applications Bis(4-hydroxy-3,5-dimethylphenyl) Sulfone (cas# 13288-70-5) is a useful research chemical.<br></p>

<p>Applications N-Phenyl-1-napthyl Amine is a chemical reactant used in the preparation of aryl halides and diarylamines. It also forms oligomers used as hole transport for green electrophosphorescence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yamamoto, T. et al.: Tetrahedron Lett., 39, 2367 (1998); Zhang, S. et al.: Dyes and Pigments., 118, 1 (2015)<br></p>

<p>Applications Tris(2,4-tert-butylphenyl) Phosphite is an intermediate in the synthesis of Tris(2,4-di-tert-butylphenyl)phosphate (T884500), a processing stabilizer for polymers.<br>References Thilen, M., et al.: J. Appl. Polym. Sci., 76, 938 (2000); Pfaendner, R., et al.: Polym. Degrad. Stab., 91, 2249 (2006);<br></p>

<p>Stability Moisture Sensitive<br>Applications Tetrabutylammonium Difluorotriphenylsilicate is used as a reagent in the synthesis of (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine ((-)-P7C3-S243); a neuroprotective chemical with improved druglike properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naidoo, J., et al.: J. Med. Chem., 57, 3754 (2014)<br></p>

<p>Applications (1R,2R)-1,2-Cyclohexanedimethanol (cas# 65376-05-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Dibenzylamine, a chemical contaminant in L-(+)-β-hydroxybutyrate, exhibits direct anticonvulsant actions in vivo.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rho, J.M., et al.: Epilepsia, 43, 358 (2002)<br></p>

<p>Applications N-(2,6-Diisopropylphenylcarbamoylmethyl)iminodiacetic Acid (cas# 65717-97-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,6-Dimethylcyclohexanol (cas# 5337-72-4) is a useful research chemical.<br></p>

<p>Applications Used in the synthesis of substituted terphenyls.<br>References Strukelj, M., et al.: Science, 267, 1969 (1995), Burroughes, J., et al.: Nature, 347, 589 (1990),<br></p>

<p>Applications 4-(ETHOXYCARBONYL)BENZOIC ACID (cas# 713-57-5) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Butyl Benzenesulfonate is an aryl-sulfonate genotoxic impurity found in trace levels in drug substances.<br>References An, J. et al.: J. Pharmac. Biomed. Anal., 48, 1006 (2008);<br></p>

<p>Applications 1,4-Cyclohexanedimethanol is extensively used as cross-linking reagent in polymer industry. It has been used in the synthesis of polyketal copolymers. It was used as diol comonomer during the synthesis of polyester-carbonates based on 1,3-propylene-co-1,4-cyclohexanedimethylene succinate.<br>References Yang, S., et al.: Bioconjugate Chem., 19, 1164 (2008); Liu, Y., et al.: J. Polym. Sci. A Polym. Chem., 39, 2508 (2011); Hungria, A., et al.: Angewandte Chemie, 45, 4782 (2006)<br></p>

<p>Applications 4-n-Butoxybenzoic acid<br></p>

<p>Applications A potential antiparasitic agent.<br></p>

<p>Stability Volatile<br>Applications Cyclohexane is a cycloalkane and used to prepare precursors of nylon such as Adipic Acid (A291590) and Caprolactam (C175665).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kalinova, Jana P., et al.: Food Chem., 157, 380-384 (2014); Kim, Y. et al.: Ind. Eng. Chem. Res., 51, 15801 (2012); Nehlsen, J., et al.: Ind. Eng. Chem. Res. 45, 518 (2006)<br></p>

<p>Applications benzo[b]fluoren-11-one (cas# 3074-03-1) is a useful research chemical.<br></p>

<p>Applications Decafluorobiphenyl is used for step−growth polymers synthesis (1).<br>References (1) Deck, P. A. and Maiorana, C. R. Macromolecules 34, 9 (2001)<br></p>

<p>Applications 1-phenylbutan-1-amine (cas# 2941-19-7) is a useful research chemical.<br></p>

<p>Stability Very Moisture Sensitive<br>Applications Chlorotriphenylstannane is used in the synthesis of nanoparticles which bear triamide ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shariatinia, Z. et al.: Beil. J. Nanotech., 4, 94 (2013);<br></p>

<p>Applications Antioxidant.<br>References Arnous, A., et al.: J. Agr. Food Chem., 49, 5736 (2001), Guendez, R., et al.: Food Chem., 89, 1 (2005), Proestos, C., et al.: Food Control,16, 319 (2005)<br></p>

<p>Applications 2-(Hydroxyimino)-3-phenylpropanoic acid (cas# 3682-17-5) is a useful research chemical.<br></p>

<p>Applications A metabolite of aldehydes.<br>References Shiobara, Y., et al.: Xenobiotica, 9, 157 (1979),<br></p>

<p>Applications Cyclohexanemethanol is a chemicl reagent used in the synthesis of potent inhibitors of cyclin-dependent kinases 1 &amp; 2.<br>References Hardcastle, I. et al.: J. med. Chem., 47, 15, 3710 (2004); Sayle, K. et al.: Bioorg. Med. Chrm. Lett., 13, 3079 (2003);<br></p>

<p>Applications Ethylbenzene is used in the industrial production of styrene trough various organic processes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weiss, W. et al.: Prog. Surf. Sci., 70, 1 (2002); Cavani, F. et al.: App. Catal. A., 133, 219 (1995);<br></p>

<p>Applications 2-(2-carbamoylphenyl)acetic acid (cas# 23362-56-3) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 1-(Trimethylsiloxy)cyclohexene is used as a reagent in the synthesis of 6-Methyl Chrysene (M265140); an aryl hydrocarbon receptor (AhR) agonist that has been listed as possibly carcinogenic to humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Amin, S. et al.: Cancer Res., 45, 6406 (1985); Blaha, L. et al.: Toxicol. Sci., 65, 43 (2002); Brack, W. et al.: Environ. Sci. Technol., 37, 3062 (2003); Andrysik, Z. et al.: Mutat. Res., 615, 87 (2007)<br></p>

<p>Stability Light Sensitive<br>Applications (2E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic Acid, is a reagent used as an analytical standard.<br></p>

<p>Applications 4,4'-Oxydibenzenesulfonyl hydrazide (cas# 80-51-3) is a useful research chemical.<br></p>

<p>Applications 2-Phenylfuran (cas# 17113-33-6) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 4-Nitrobenzoic Acid is used in the synthesis of anti-Trypanosoma cruzi agents in the treatment of chagas disease.<br>References Palace-Berl, F. et al.: Bioorg, Med. Chem. Lett., 21, 5395 (2013); Zhou, L. et al.: J. Med. Chem., 56, 796 (2013);<br></p>

<p>Stability Very Very Moisture Sensitive<br>Applications Dichlorotriphenylphosphorane is a reagent used in the synthetic preparation of sulfonamides. Also used to prepare O-alkylated benzamides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chen, Y. et al.: RSC. Adv., 5, 4171 (2015); Prabhakaran, P. et al.: Tetrahedron, 68, 4485 (2012);<br></p>

<p>Applications 3-Isopropoxybenzoic acid is a useful reagent for organic synthesis and other chemical processes.<br>References Chiong, H. A., et al.: J. Am. Chem. Soc., 129, 9879 (2007); Kingston, D. G. I., et al.: J. Med. Chem., 41, 3715 (1998)<br></p>

<p>Applications 2,4-Dihydroxybenzoic acid is a useful synthetic intermediate. An organic building block for plastics and rubber products.<br>References Gautam, R., et al.: Cryst. Growth Des., 18, 1501 (2018); Shvedene, N. V., et al.: J. Anal. Chem., 72, 95 (2017);<br></p>

<p>Stability Light Sensitive, Unstable in Solution<br>Applications α,α-Bis[4-(dimethylamino)phenyl]-4-(methylamino)-benzenemethanol is a product from degradation of methyl green.<br>References Chen, C., et al.: Environ. Sci. Technol., 41, 4389 (2007)<br></p>

<p>Applications N-[4-(-Carboxycyclohexylmethyl)]maleamidic Acid (cas# 72748-87-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(3-Aminophenyl)-3-morpholinone is an intermediate during the preparation of imidazothiazoles as protein kinase inhibitors for treating cancers.<br>References Bamaung, N., et al.: PCT Int. Appl. (2009), WO 2009070516 A1 20090604.<br></p>

<p>Applications Methyl 2-Bromomethylbenzoate is a reactant in the preparation of Methyl 2-((4-(2-(2-methylphenoxy)acetyl)piperazin-1-yl)methyl)benzoate with neuroprotective activity.<br>References Zhong, Y., et. al.: Chin. J. Struct. Chem., 33, 1096 (2014)<br></p>

<p>Applications 3-Carboxyphenylboronic Acid is used in phenylboronic acid-decorated gelatin nanoparticles for enhanced tumor targeting and penetration.<br>References Wang, X., et al.: Nanotechnology, 27, 385101 (2016); Wang, X., et al.: Eur. J. Pharm. Biopharm., 113, 168 (2017)<br></p>

<p>Applications Benzo[b]thiophene has application in organic as well as pharmaceutical industry as a component in the synthesis of Raloxifene, a breast cancer therapeutic, or hydrodesulfurization reactions.<br>References Buccella, D. et al.: J. Am. Chem. Soc., 130, 16187 (2008); Gennari, L. et al.: Exp. Opin. Drug Saftey, 7, 259 (2008);<br></p>

<p>Applications 4-(diethylamino)benzophenone (cas# 18127-87-2) is a useful research chemical.<br></p>

<p>Applications 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases.<br>References McCarthy, T.D., et al. PCT Int. Appl. WO 2013102242 A1 20130711. Jul 11, 2013<br></p>

<p>Applications 1-Phenyl-2-butanamine (cas# 30543-88-5) is a useful research chemical.<br></p>

<p>Applications Mesitoic acid can be used for its antioxidant.<br>References Thomas, P.S., et.al.: Medicines, 4, 1-7, (2017);<br></p>

<p>Applications 4-(Benzyloxy)butanoic acid<br></p>

<p>Applications 2,4-Dioxo-4-phenylbutanoic acid<br></p>

<p>Applications 3-Cyclohexenylcarboxylic Acid has been found to be an oxidizable, nongrowth substrate and induces the metabolism of cyclohexanecarboxylic acid and benzoic acid in a strain of Pseudomonas putida. 3-Cyclohexenylcarboxylic Acid has been used as food for cultures of Streptomyces sp.  KCTC 11604BP fkbO deletion mutant to make 32-dehydroxy-FK506, a FK506 analogue containing a non-natural starter unit.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Blakley, E.R., Papish, B.: Can. J. Microbiol., 28, 1324 (1982); Ban, Y.H., et. al.: Mol. bioSystems, 9, 944 (2013)<br></p>