Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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UDP-N-azidoacetylgalactosamine triethylamine
CAS :<p>UDP-N-azidoacetylgalactosamine (UDP-GlcNAz) is an analogue of UDP-GalNAc, bearing an azido group on the N-acyl side chain. It acts as an unnatural substrate for the polypeptide N-R-acetylgalactosaminyltransferases (ppGalNAcTs) which are enzymes that play a role in mucin-type O-linked glycoprotein biosynthesis. UDP-GlcNAz is accepted as a nucleotide-sugar donor, appending an azidosugar onto its native substrates, which can then be detected using azide-reactive chemical probes. The azide group can be detected by the conjugation with phosphine probes via the Staudinger ligation, or alkyne probes via cycloaddition reactions.</p>Formule :C17H26N6O17P2Degré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :848.73 g/molAdenosine 5′-phosphosulfate sodium salt
CAS :Adenosine 5′-phosphosulfate sodium salt has been used quantify pyrophosphate and in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP)Formule :C10H14N5O10PSDegré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :427.29 g/molAdenosine - Endotoxin level below 1000 EU/g
CAS :Adenosine is a naturally-occurring organic solvent found in the human body. It has been shown to inhibit fibroid growth and to have an anti-inflammatory effect on the uterus. Adenosine is also a potent endogenous vasodilator, which may be due to its ability to activate adenosine receptors. In addition, it has been demonstrated that adenosine inhibits the synthesis of target enzymes such as collagenase and hyaluronidase. The uptake of adenosine by cells is inhibited by nevirapine, which is an HIV protease inhibitor. This inhibition leads to increased extracellular levels of adenosine, which stimulates phosphorylation of extracellular-regulated kinases (ERKs) and decreases histamine release from mast cells. The ERKs are activated in response to many stimuli including cytokines, growth factors, and stressors such as UV light or heat shock.BR> In vitro studies using human tissue have shown that adFormule :C10H13N5O4Degré de pureté :(Titration) 99.0 To 101.0%Couleur et forme :White Off-White PowderMasse moléculaire :267.24 g/mol4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine ammonium
CAS :<p>The 4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine ammonium salt is a solvent that has been used in the synthesis of various organic and inorganic compounds. It is a five membered ring compound with solvents, such as chlorides, and it can be found in diffraction patterns. 4-Amino-6-hydroxy-2-mercapto-5 nitrosopyrimidine ammonium salt can also act as a ligand in metal complexes. The molecule has carbonyl groups which chelate to the metal atom and form a ring with chlorine atoms.</p>Formule :C4H4N4O2S•NH3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :189.2 g/mol6-Chloro-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS :<p>6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analogue that inhibits the replication of the hepatitis C virus. It binds to the viral RNA polymerase and blocks the synthesis of viral RNA, thereby preventing infection. This drug also has antiviral activity against HIV and herpes simplex viruses. The antiviral effect is due to its ability to inhibit phosphatases and carboxylates, which are involved in the initiation of mRNA transcription and protein translation, respectively. 6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is metabolized by deoxyadenosine kinase into 6-chloropurine ribonucleotide, which can be converted into other purines.</p>Formule :C10H11ClN4O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :270.68 g/molThymidine-5'-monophosphate disodium salt
CAS :<p>Thymidine-5'-monophosphate disodium salt is a nucleoside that is synthesized by reductive phosphorylation of thymidine. It is a substrate for nucleotide synthesis and can be used as a reagent in the synthesis of oligonucleotides. Thymidine-5'-monophosphate disodium salt can be reduced to form thymidine, which can then be converted to 5-thio-2'-deoxyuridylate or 5-thio-2'-deoxycytidylate. This conversion takes place through the cleavage reaction of the thymidine residue from the disodium salt.</p>Formule :C10H13N2Na2O8PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :366.17 g/mol9-(b-D-Arabinofuranosyl)guanine
CAS :<p>9-(b-D-Arabinofuranosyl)guanine is an arabinoside derivative that has high affinity for DNA. 9-(b-D-Arabinofuranosyl)guanine binds to the phosphate groups in DNA and inhibits the synthesis of DNA. It is used in vitro assays to study molecular pathogenesis and in vivo as a drug against leukemia, lymphomas, and other cancers. 9-(b-D-Arabinofuranosyl)guanine also inhibits protein synthesis by binding to ribosomes. This drug can cause significant side effects such as gastrointestinal distress, diarrhea, nausea, vomiting, and abdominal pain. It can also cause blood dyscrasias and liver damage.</p>Formule :C10H13N5O5Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :283.24 g/molN6-Acetyladenosine
CAS :<p>N6-Acetyladenosine is a nucleoside that belongs to the group of N-acetylated adenosines. It is found in thermophilic organisms and has been shown to be involved in optimal growth. N6-Acetyladenosine has also been found to be an important part of the coding and population modifications of crenarchaeota, archaeal organisms that are phylogenetically related to methanogens. Unfractionated populations of methanogen contain both N6-acetyladenosine residues and other modified adenosines, with each organism differing in the types of modifications they contain. Transfer of these modified adenosines from one organism to another can lead to changes in their coding and population modifications.</p>Formule :C12H15N5O5Degré de pureté :Area-% Min. 90 Area-%Couleur et forme :White PowderMasse moléculaire :309.28 g/mol2',3'-O-Isopropylideneuridine
CAS :<p>2′,3′-O-Isopropylideneuridine serves as a key intermediate in the chemical synthesis of N-benzoyl uridine derivatives and N3-substituted 2′,3′-O-isopropylideneuridines, which exhibit central nervous system (CNS) depressant properties</p>Formule :C12H16N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :284.27 g/mol2'-Deoxy-5-formyluridine
CAS :<p>2'-Deoxy-5-formyluridine (2DFO) is a nucleobase analogue that inhibits the enzymatic activity of DNA glycosylases, which are enzymes that remove sugar residues from damaged DNA. 2DFO has been shown to induce apoptosis in cancer cells by inhibiting DNA synthesis and promoting oxidative damage to the cell's DNA. 2DFO has also been shown to inhibit the growth of DU-145 cells in vitro and in vivo models. This drug was found to be more effective at preventing metastasis of colorectal cancer when it was administered with a platinum-based chemotherapy drug.</p>Formule :C10H12N2O6Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :256.21 g/mol2'-Deoxy-L-guanosine
CAS :<p>2'-Deoxy-L-guanosine is a nucleoside that is used as an antibiotic. It inhibits protein synthesis, which leads to cell death. This drug has a high level of resistance against bacteria and is effective in the treatment of gram-positive bacteria. 2'-Deoxy-L-guanosine binds to the ribose phosphate backbone of DNA, phosphorylating it and preventing the base pairing of adenosine with thymine. This inhibits the production of DNA and RNA, leading to cell death. 2'-Deoxy-L-guanosine has been shown to be active against Listeria monocytogenes and Mycobacterium tuberculosis. The enantiomer form is more potent than the racemic mixture, but both forms are effective antibiotics.</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :267.25 g/molS-Adenosyl-L-methionine p-toluenesulfonate
CAS :<p>Methyl donor and a cofactor for enzyme-catalyzed methylations</p>Formule :C15H23N6O5S•C7H7O3SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :570.64 g/mol5-(2-Amino-2-oxoethyl)-2-thiouridine
CAS :<p>5-(2-Amino-2-oxoethyl)-2-thiouridine is a modified deoxyribonucleoside that is used as a phosphoramidite to synthesize oligonucleotides. 5-(2-Amino-2-oxoethyl)-2-thiouridine inhibits the synthesis of viral DNA and RNA, and its antiviral activity has been shown in vitro. It also may have anticancer activity due to its ability to inhibit DNA synthesis and cell proliferation. This compound has high quality, high purity, and novel properties.</p>Formule :C11H15N3O6SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :317.32 g/mol5-Bromocytidine
CAS :<p>5-Bromocytidine is a pyrimidine nucleoside that has been shown to inhibit the replication of influenza virus in cell culture. It stabilizes the ribonucleotide reductase enzyme, which is responsible for converting ribonucleosides to deoxyribonucleosides. This inhibition prevents the production of viral RNA and protein synthesis, leading to inhibition of viral growth. 5-Bromocytidine has also been shown to have antiviral effects against HIV and herpes simplex virus type 1 (HSV1) in cell cultures.</p>Formule :C9H12BrN3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :322.11 g/molN4-Aminocytidine
CAS :<p>N4-Aminocytidine is an analog of uridine that can be used as an inhibitor of the growth of bacteria. It has been shown to inhibit the growth of Escherichia coli and Salmonella typhimurium in vitro. N4-Aminocytidine binds to the bacterial ribosome and inhibits protein synthesis, which results in cell death. This drug has also been found to act as a potent synthetic cannabinoid receptor agonist in vivo and inhibits uptake of cannabinoids into cells in culture. N4-Aminocytidine has also been shown to bind to dna duplexes and chemically react with them, altering their structure. This drug has not yet been tested for safety or efficacy in humans.</p>Formule :C9H14N4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :258.23 g/mol1,3-Dimethylpseudouridine
CAS :<p>1,3-Dimethylpseudouridine is a methylated derivative of pseudouridine, which is a naturally occurring modified nucleoside found in RNA. This compounds can be used in research applications</p>Formule :C11H16N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :272.25 g/mol3'-O-Aminothymidine
CAS :<p>3'-O-Aminothymidine is an isomer of thymidine, a nucleoside that is found in DNA and RNA. It has a neutral charge and belongs to the category of nucleosides. 3'-O-Aminothymidine is synthesized by the coupling of an amino group with a hydroxyl group. This reaction is efficient and can be used to produce dimers. 3'-O-Aminothymidine can also be used as a precursor for other nucleotides or as a synthetic intermediate in other chemical reactions.</p>Formule :C10H15N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :257.24 g/molStearoyl coenzyme A lithium
CAS :<p>Stearoyl coenzyme A lithium is a novel modified ribonucleoside that is synthesized by enzymatic phosphorylation of 3'-deoxyribonucleosides. It has anticancer, antiviral, and antitumor activities. Stearoyl coenzyme A lithium is a monophosphate nucleotide which activates the transcription factors that regulate gene expression and replication. The drug also inhibits viral replication through competitive inhibition of the viral DNA polymerase.</p>Formule :C39H70N7O17P3S·xLiDegré de pureté :90%Couleur et forme :PowderMasse moléculaire :1,034 g/mol8-Bromoguanosine
CAS :<p>8-Bromoguanosine (8BrG) is a potent inhibitor of cyclase enzymes that lead to the formation of cyclic guanosine monophosphate (cGMP). It has been shown to inhibit signal pathways, such as those regulated by the G protein-coupled receptor (GPCR), which are activated by the 2-adrenergic receptor. 8BrG has been shown to be effective against C. glabrata and other fungi and has been used in experimental models for infectious diseases.</p>Formule :C10H12BrN5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :362.14 g/mol2'-Deoxy-N2-isobutyrylguanosine
CAS :<p>2'-Deoxy-N2-isobutyrylguanosine (2'-DIBG) is an inhibitor of bacterial translocation that has been shown to inhibit the growth of several bacterial species. This drug binds to fatty acids, which are important for maintaining the integrity of the cell membrane and preventing bacterial translocation. 2'-DIBG also inhibits the production of reactive oxygen species by bacteria, which contributes to its antimicrobial activity. Inflammation can be reduced by inhibiting prostaglandin synthesis with 2'-DIBG. The inhibition of prostaglandin synthesis may be due to its ability to form acid conjugates with fatty acids and dicarboxylic acids, which are precursors for prostaglandins. 2'-DIBG also inhibits the synthesis of adenosine triphosphate (ATP) in bacteria, leading to a decrease in bacterial growth rate.</p>Formule :C14H19N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :337.34 g/mol
