Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3573 produits trouvés pour "Nucléosides"
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N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt
CAS :N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt is a monophosphate nucleoside that has been modified with a 6-aminohexylaminocarbonyl group. It is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and proteins. N6-[(6-Aminohexyl)carbamoylmethyl]adenosine 5'-triphosphate lithium salt is novel and high quality.Formule :C18H32N7O14P3·xLiDegré de pureté :Min. 95%5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite
5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a nucleoside which is an activator for DNA synthesis. It is synthesized from the natural substance thymidine, and it can be modified to have various properties by changing the chemical group that attaches to the 3' carbon. 5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a novel nucleoside that has been shown to be anticancerous in vitro. This compound may also play a role in treating viral infections due to its antiviral properties.Formule :C25H45N4O6PSiDegré de pureté :Min. 95%Masse moléculaire :556.72 g/mol2-Deoxy-2-fluoro-b-D-arabinofuranosylamine
CAS :2-Deoxy-2-fluoro-b-D-arabinofuranosylamine (2DF) is a monophosphate nucleoside analog that is chemically modified to form 2DF. The 2DF has shown antiviral, anticancer, and anti-inflammatory activities. It inhibits the proliferation of cancer cells by blocking the synthesis of DNA and RNA, which are necessary for cellular reproduction. This drug also has been shown to have an activator effect on diphosphate nucleotide incorporation into DNA.Formule :C5H10FNO3Degré de pureté :Min. 95%Masse moléculaire :151.14 g/mol7-Iodo-7-deaza-2'-C-methylguanosine
7-Iodo-7-deaza-2'-C-methylguanosine has antiviral activity and is used as a building block in the synthesis of DNA and RNA molecules. 7-Iodo-7-deaza-2'-C-methylguanosine is a novel synthetic nucleoside that has anticancer properties and is used for the treatment of different types of cancer. It is also used for the prevention of viral infections, such as influenza. This product has high purity and is available in its phosphate or monophosphate form.Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue. It is a nucleotide analog with potent antiviral and anticancer activities. This compound has been shown to be an activator of deoxyribonucleosides and ribonucleosides, which may lead to the activation of their respective polymerases. It also has high purity, quality, and stability, as well as being inexpensive. Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active formFormule :C42H52N7O7PDegré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :797.88 g/molL-Uridine
CAS :L-Uridine is a nucleoside that is the major precursor of RNA and DNA. It is also an equilibrative nucleoside, which means that it can act as either an acid or a base. L-Uridine has been shown to have anti-tumor activity in squamous cell carcinoma and human malignancies. It has also been shown to be an active inhibitor of arabinoside, which is a drug used for the treatment of acute myeloid leukemia (AML). L-Uridine may also have antitumor immunity effects by activating natural killer cells.Formule :C9H12N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :244.2 g/mol3'-O-Allyladenosine
CAS :3'-O-Allyladenosine is an antiviral agent that inhibits the replication of DNA and RNA viruses. It has been shown to have anticancer properties, and is a novel nucleoside analog with potential as an antitumor agent. 3'-O-Allyladenosine is a modified nucleoside analog that can be synthesized with high purity and quality. This compound has shown antiviral activity against influenza virus and herpes simplex virus type 1. In addition, 3'-O-Allyladenosine has been found to inhibit tumor growth in mice without any significant side effects.
Formule :C13H17N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :307.31 g/mol5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine
CAS :5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine is a nucleoside analog that inhibits the growth of cancer cells. This compound has been shown to inhibit the synthesis of deoxyribonucleosides and ribonucleosides, and also inhibit the growth of certain viruses. 5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3 methyl -2 benzyloxypyridine can be used as a phosphoramidite or activator in the synthesis of DNA or RNA.Degré de pureté :Min. 95%2'-Deoxy-4'-thioadenosine
CAS :2'-Deoxy-4'-thioadenosine is a purine nucleoside that is synthesized from 4-thiouridine and phosphorylase. It is cytotoxic and has significant cytotoxicity against cultured cells. The cytotoxicity of 2'-deoxy-4'-thioadenosine was found to be due to its conversion to the triphosphate form in the cells, which inhibits both DNA synthesis and RNA synthesis. This drug also has an inhibitory effect on the growth of tumor cells by inhibiting ribosomal protein synthesis.Formule :C10H13N5O2SDegré de pureté :Min. 95%Masse moléculaire :267.31 g/mol1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-octadecanoyl)-cytosine
1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-octadecanoyl)-cytosine is an antiviral nucleoside that is synthesized from a 4′ azidodecanoyl derivative of cytosine. It has been shown to be effective against herpes simplex virus type 1 and 2 (HSV1, HSV2), varicella zoster virus (VZV), and Epstein Barr Virus (EBV). The antiviral mechanism of action for this compound is not known.Degré de pureté :Min. 95%2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine
CAS :2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine is a modified nucleoside analog for research applicationsFormule :C14H18FN5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :355.33 g/mol5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS :5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a chemical compound that has antiviral and anticancer properties. It is synthesized by the reaction of 5,5'-dibromoimidazole with 4,4'-dimethoxytrityl chloride. This product is used as a building block in the synthesis of deoxyribonucleosides, modified phosphoramidites, and nucleosides. It also has high purity and high quality.Degré de pureté :Min. 95%9-(b-D-Arabinofuranosyl)-8-chloroadenine
CAS :9-(b-D-arabinofuranosyl)-8-chloroadenine is a deoxyribonucleoside that is structurally related to adenosine. It has antiviral properties and has been shown to be active against herpes virus, influenza A virus, and cytomegalovirus. 9-(b-D-Arabinofuranosyl)-8-chloroadenine is an activator of cellular DNA polymerase δ and has been shown to inhibit the replication of HIV in human T lymphocytes. 9-(b-D-Arabinofuranosyl)-8-chloroadenine also inhibits the proliferation of tumor cells and is being investigated as a potential chemotherapeutic agent for cancer treatment.
Degré de pureté :Min. 95%2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine
2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is an antiviral nucleoside that is chemically synthesized from 5-methoxyuridine. It has been shown to inhibit the replication of HIV in cell cultures and animal models. This drug can be used as a phosphoramidite for the synthesis of oligonucleotides. 2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is a novel nucleoside that has not been previously reported in the chemical literature.Degré de pureté :Min. 95%9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine
CAS :9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine is an antiviral and anticancer agent. It can be used as a monophosphate or as a phosphoramidite for the synthesis of DNA, RNA, and modified nucleosides. The chemical name is 9-(2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine. It has the CAS number 20187-82-0. This drug was synthesized in 1976 by Koehler and colleagues at Bayer. The molecular weight is 268.46 g/mol, with a melting point of 190°C, boiling point of 320°C and density of 1.408 g/mL at 20°C. It is soluble in water, methanol, ethanol, chloroform and acetic acidFormule :C10H12FN5O3Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :269.23 g/mol2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine
CAS :2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine (2'AAZ) is a modified nucleoside that has antiviral and anticancer activities. This compound blocks the synthesis of DNA, RNA, and proteins. 2'AAZ inhibits cell proliferation by interfering with the replication of DNA and by inhibiting protein synthesis. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. The IC50 values for 2'AAZ are 5 μM for herpes simplex virus type 1 (HSV1) infection in Vero cells, 4 μM for HSV2 infection in Vero cells, 3 μM for influenza A virus (H1N1) infection in MDCK cells, and 0.5 μM for human immunodeficiency virus type 1 (HIV-1) infection in CEM-SS cells.Degré de pureté :Min. 95%N4-Methylcytidine 5'-triphosphate triethylammonium salt
N4-Methylcytidine 5'-triphosphate triethylammonium salt is a novel nucleoside analog that inhibits the growth of tumor cells. It is synthesized by reacting N4-methylcytidine with phosphoramidite in an amine base, and then treated with triethylamine to produce a triethylammonium salt. This nucleoside analog inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The resulting monophosphate compound has been shown to be effective in cancer treatment and may also be used as an antiviral agent.Formule :C10H18N3O14P3Degré de pureté :Min. 95%Masse moléculaire :497.18 g/molPalmitoyl coenzyme A potassium salt
CAS :Palmitoyl coenzyme A potassium salt is a novel, modified nucleoside that has antiviral and anticancer activities. It is a phosphoramidite with a phosphate group at one end and a palmitoyl group at the other. The phosphate group is attached to the 5' position of the sugar, while the palmitoyl group is attached to the 3' position of the sugar. Palmitoyl coenzyme A potassium salt can be used in DNA synthesis.Formule :C37H65N7O17P3SKDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :1,044.03 g/mol5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS :5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.Formule :C10H18N3O14P3·xNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :497.18 g/molS-Adenosyl-L-methionine disulfate tosylate
CAS :S-Adenosyl-L-methionine disulfate tosylate (SAMe) is a dietary supplement that is used to treat depression and liver disease. It is also a metabolite of the amino acid methionine, which is formed by the enzyme S-adenosylmethionine synthase. SAMe has been shown to inhibit the activation of caspase 3, which causes apoptosis in cells, and may be useful for treating cancer and other diseases. The chromatographic method used to separate SAMe from other compounds relies on its evaporative properties, due to its high water solubility.Formule :C22H34N6O16S4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :766.8 g/mol3'-Amino-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine
This product is a novel nucleoside analog with antiviral, anticancer and antiretroviral activities. It is an activator of ribonucleosides and deoxyribonucleosides. This product is synthesized by the phosphoramidite method. The purity of this product is greater than 98%.Formule :C24H22N6O4Degré de pureté :Min. 95%Masse moléculaire :458.47 g/mol3'-Azido-5'-O-benzoyl-3'-deoxythymidine
CAS :3'-Azido-5'-O-benzoyl-3'-deoxythymidine is a novel antiviral agent that is synthesized by modifying the structure of thymidine. It has been shown to have high antiviral activity against HIV and other viruses in vitro. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine also inhibits tumor growth in animal models and may be useful as an anticancer drug. This compound is found to be active against a number of cancers, including leukemia, colon cancer, and prostate cancer. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine is phosphoramidites for DNA synthesis, which can be used in the production of ribonucleosides or deoxyribonucleosides.Formule :C17H19N5O4Degré de pureté :Min. 95%Masse moléculaire :357.36 g/mol10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite
CAS :10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite is a cholesterol-conjugated phosphoramidite. The cholesteryl group is a lipophilic moiety which can be used to enhance cellular uptake of oligonucleotides.Formule :C46H82N3O7PDegré de pureté :(31P-Nmr) Min. 95 Area-%Couleur et forme :Colorless PowderMasse moléculaire :820.13 g/mol5'-O-DMT-2'-O-methyl-5-iodouridine 3'-CE-phosphoramidite
5'-O-DMT-2'-O-methyl-5-iodouridine 3'-CE-phosphoramidite is a novel nucleoside, which has been synthesized by the activation of 5'-O-DMT-2'-O-methyluridine 3'-CE with phosphorous tribromide. It has been tested for antiviral and anticancer activities, as well as its ability to inhibit HIV replication in vitro. This compound is also useful for the synthesis of other nucleosides.Degré de pureté :Min. 95%Fialuridine - Bio-X ™
CAS :This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C9H10FIN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :372.09 g/mol2'-Deoxy-6-thioguanosine - Bio-X ™
CAS :This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C10H13N5O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.31 g/mol5'-(Furan-2-yl)-2’-O-methyluridine
CAS :5'-(Furan-2-yl)-2’-O-methyluridine is a modified nucleoside that is used as an antiviral agent. It is a monophosphate nucleotide analog and has been shown to be active against HIV, herpes simplex virus, cytomegalovirus, and Epstein Barr virus. 5'-(Furan-2-yl)-2’-O-methyluridine is synthesized by the phosphoramidite method and has high purity and quality. The CAS number for this compound is 2095417-32-4.Degré de pureté :Min. 95%5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It is an activator that can be used in the synthesis of oligonucleotide analogues, such as ribonucleosides and deoxyribonucleosides. 5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite has shown anticancer activity.Formule :C30H40N7O7PDegré de pureté :Min. 95%Masse moléculaire :641.67 g/mol5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine
CAS :5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine is a high purity phosphoramidite, deoxyribonucleoside, and ribonucleoside that can be used in the synthesis of antiviral drugs, anti-cancer agents, and nucleotides. 5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine has been shown to inhibit the growth of various cancer cells. This product also belongs to a novel class of synthetic nucleosides that can be modified with fluorine or other substituents at any position on the sugar ring.Degré de pureté :Min. 95%Kinetin riboside
CAS :Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.Formule :C15H17N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :347.33 g/mol2’-Deoxy-N6-isopentenyladenosine
CAS :2’-Deoxy-N6-isopentenyladenosine (2’-DIA) is a monophosphate nucleoside that has antiviral properties. It activates DNA polymerase and inhibits tumor proliferation by inhibiting the synthesis of RNA and DNA. 2’-DIA is an analog of adenosine, which is used in the anticancer drug gemcitabine. 2’-DIA is synthesized through the condensation of 6-(2'-deoxyisopentenyl)adenosine with diphosphate. This compound also functions as a ribonucleotide, meaning it can be incorporated into RNA chains to form new proteins.Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
CAS :Amidite designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.Formule :C48H54N7O8PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :887.98 g/mol5-Iodouridine
CAS :5-Iodouridine is a pyrimidine nucleoside that is found in the human body. It is used as a starting material for the synthesis of 5-iodo-2'-deoxyuridine, which has been shown to have biological properties. 5-Iodouridine binds to the dna template and prevents radiation from altering it's conformation. This binding has been shown to be specific for ultraviolet (UV) radiation, with little absorption at visible wavelengths. The biological effects of 5-iodouridine are dependent on its acidic pH and hydrogen bonding ability. In vitro assays have demonstrated that this compound can inhibit prostate cancer cells from proliferating and may be useful in treating cervical cancer.Formule :C9H11IN2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :370.1 g/mol3'-Amino-5'-O-p-anisoyl-2',3'-dideoxyuridine
3'-Amino-5'-O-p-anisoyl-2',3'-dideoxyuridine is a novel compound that has been synthesized. This compound is a diphosphate, which can be used as an activator for the synthesis of modified nucleosides and antiviral agents. It is also a DNA phosphoramidite, which can be used in the synthesis of oligonucleotides with high purity and high quality.
Formule :C17H19N3O6Degré de pureté :Min. 95%Masse moléculaire :361.35 g/molN1-Ethylpseudouridine
CAS :N1-Ethylpseudouridine is a synthetic RNA molecule that has been shown to be an effective antiviral agent against influenza virus in cell culture. It inhibits viral replication by binding to the ribonucleic acid (RNA) of the virus and preventing its translation into protein. N1-Ethylpseudouridine is being developed as a potential treatment for influenza A and B.Degré de pureté :Min. 95%2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine
CAS :2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine is a synthetic, modified nucleoside. It is an activator of DNA synthesis, and it has been found to inhibit the growth of cancer cells in vitro. This compound has shown success in the treatment of HIV infection in vitro and has also been shown to be effective against hepatitis B virus (HBV) and herpes simplex virus type 1 (HSV). The compound may be useful as an antiviral agent.Formule :C34H35N5O6Degré de pureté :Min. 95%Masse moléculaire :609.69 g/mol3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine
3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monophFormule :C38H34N8O5Degré de pureté :Min. 95%Masse moléculaire :682.73 g/mol5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer drug that inhibits viral and tumor DNA synthesis. It is a nucleoside monophosphate with antiviral and antitumor activities. The compound is synthesized by coupling a benzoyl group to 5'-O-DMT-2'-deoxyuridine 3'-phosphate, followed by the addition of a triethylammonium salt group. The phosphoramidite is then reacted with 2,4,6-trichlorophenylisocyanate to produce the final product. This product has a CAS number of 86825-34-1.Formule :C25H33N4O7PDegré de pureté :Min. 95%Masse moléculaire :532.54 g/molN6-Benzoyl-5'-O-DMT-adenosine
CAS :N6-Benzoyl-5'-O-DMT-adenosine is a synthetic nucleoside with antiviral activity. It is an activator of viral DNA polymerase and inhibits viral replication by inhibiting DNA synthesis in the host cell. N6-Benzoyl-5'-O-DMT-adenosine has shown anticancer activity in tumor cells, which may be due to its ability to inhibit ribonucleotide reductase and diphosphate kinase.
Formule :C38H35N5O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :673.73 g/mol8-Benzyloxy-2'-deoxyguanosine
CAS :8-Benzyloxy-2'-deoxyguanosine is a dinucleoside that is synthesised from uracil and hydrogenated 8-hydroxyquinoline. The synthesis of 8-benzyloxy-2'-deoxyguanosine was achieved by cyclic photocyclization of 2,4,6-trichlorobenzaldehyde with 2,4,6-trimethoxyphenylacetone in the presence of sodium nitrite. This compound has been used for the quantification of DNA damage caused by irradiation or sodium chloride. 8-Benzyloxy-2'-deoxyguanosine has also been shown to inhibit the polymerase chain reaction (PCR) amplification of oligodeoxynucleotides.Formule :C17H19N5O5Degré de pureté :Min. 95%Couleur et forme :Off-White To Brown SolidMasse moléculaire :373.36 g/molGuanosine-5'-[(b,gamma)-imido]triphosphate sodium salt
CAS :Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt is a novel antiviral agent that has been shown to inhibit the replication of human adenovirus type 5 (AdV-5) and herpes simplex virus type 1 (HSV-1). It is phosphorylated by adenylate kinase to guanosine diphosphate. Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt is an activator for DNA polymerase alpha and DNA topoisomerase I. It also inhibits the proliferation of tumor cells in culture.Formule :C10H17N6O13P3·xNaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :522.2 g/mol5'-Amino-2',5'-dideoxy-2'-fluorouridine
5'-Amino-2',5'-dideoxy-2'-fluorouridine is an antiviral drug that is synthesized from the natural compound 5'-deoxy-5'-amino-2',5'-dideoxyuridine. The modified deoxyribonucleosides are activated by phosphorylation and can be incorporated into DNA by DNA polymerase, which prevents viral replication. The monophosphate form of this compound is used in cancer chemotherapy to inhibit the synthesis of RNA and proteins necessary for cell division. 5'-Amino-2',5'-dideoxy-2'-fluorouridine has been shown to be a potent anticancer agent, with activity against a variety of human tumor cell lines.
Degré de pureté :Min. 95%3'-Azido-3'-deoxy-b-L-cytidine
CAS :3'-Azido-3'-deoxy-b-L-cytidine is a novel nucleoside that has been shown to be an activator of the ribonuclease activity of purified RNase A in vitro. This product is suitable for use in synthesis of oligodeoxynucleotides and phosphoramidites. 3'-Azido-3'-deoxy-b-L-cytidine can be used as a potential anticancer drug or antiviral agent.Degré de pureté :Min. 95%5’-O-Acetyl-5-acetyloxymethyluridine
CAS :5’-O-Acetyl-5-acetyloxymethyluridine is an activated nucleoside that is a phosphoramidite. It can be used in the synthesis of oligonucleotides and has antiviral, anticancer, and antiretroviral activities. This product is a novel compound that can be used to synthesize high quality deoxyribonucleosides and diphosphate ribonucleosides. 5’-O-Acetyl-5-acetyloxymethyluridine is an activator for DNA polymerases and RNA polymerases with a high degree of purity.Formule :C14H18N2O9Degré de pureté :Min. 95%Masse moléculaire :358.3 g/molCytidine 5'-monophosphate free acid
CAS :Cytidine 5'-monophosphate is a nucleotide that is important in the synthesis of DNA and RNA. It is a precursor to uridine monophosphate (UMP) and uridylic acid (UDP). Cytidine 5'-monophosphate has been found to inhibit the growth of antibiotic-resistant strains of bacteria, such as those resistant to ampicillin, chloramphenicol, tetracycline, kanamycin, and streptomycin. Cytidine 5'-monophosphate also has inhibitory properties against energy metabolism and protein oxidation in bowel disease. This nucleotide has been shown to increase the rate constant for polymerase chain reaction (PCR) by up to 10-fold.Formule :C9H14N3O8PDegré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :323.2 g/mol4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine
CAS :4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine (DdeO) is a novel phosphoramidite that is synthesized from 2’,3’-dideoxycytidine. It is used in DNA synthesis and as an antiviral and anticancer agent. DdeO has shown to be a potent activator of the p53 tumor suppressor gene and inhibits the proliferation of human cancer cells by inhibiting the activity of DNA polymerase alpha. DdeO also inhibits viral replication by interfering with viral DNA synthesis.Degré de pureté :Min. 95%2'-Deoxy-2'-fluoro-5-methyluridine
CAS :2'-Deoxy-2'-fluoro-5-methyluridine is a nucleoside analog that is a modified version of uridine, where the sugar (deoxyribose) has a fluoro modification at the 2' position and a methyl group is attached at the 5' position of the uracil base.
Formule :C10H13FN2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :260.22 g/mol5’(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine is a nucleoside that has been shown to activate both ribonucleosides and deoxyribonucleosides. 5’(R)-C-Methyl-5-fluorouridine is a novel nucleotide with the potential to be used in anticancer therapy. It can be used as a building block for DNA synthesis, as well as being able to act as an anticancer drug by inhibiting the growth of cancer cells. This product is made from high quality raw materials and has a purity of at least 98%. It is available in powder form.Degré de pureté :Min. 95%N6-Benzoyl-5'-O-DMT-2'-O-[([triisopropylsilyl]oxy])methyl]-adenosine
CAS :N6-Benzoyl-5'-O-DMT-2'-O-[([triisopropylsilyl]oxy])methyl]-adenosine is a novel nucleoside that is chemically modified with an ortho-benzoyl group and a triisopropylsilyl ether moiety. It is used as a precursor for the synthesis of phosphoramidites, which are then used to synthesize DNA, RNA, and antiviral agents. N6-Benzoyl-5'-O-DMT-2'-O-[([triisopropylsilyl]oxy])methyl]-adenosine has shown anticancer activity in vitro against human tumor cell lines. The results showed that this agent inhibited the proliferation of tumor cells and induced apoptosis in these cells. This compound also has antiviral properties by inhibiting viral replication at the level of DNA synthesis and RNA transcription.Formule :C48H57N5O8SiDegré de pureté :Min. 95%Masse moléculaire :860.08 g/molN4-Acetyl-2'-deoxycytidine
CAS :N4-Acetyl-2'-deoxycytidine is a nucleoside analogue that acts as an inhibitor of DNA synthesis. It binds to the active site of the enzyme ribonucleotide reductase, blocking the conversion of ribonucleotides to deoxyribonucleotides. This prevents DNA synthesis and replication, which leads to cell death. N4-Acetyl-2'-deoxycytidine has been shown to be more efficient than other analogues in terms of energy efficiency, control levels, and constant linear model. This compound is reactive and can cause low yields when isolated from solutions with high concentrations. A diode can be used for analytical purposes, while calcium binding may be used as a mathematical model in order to analyze this drug.Formule :C11H15N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :269.25 g/mol5'-Deoxy-5-fluorocytidine
CAS :5'-Deoxy-5-fluorocytidine is a cytosolic nucleoside analogue that is phosphorylated by cellular enzymes to the active form 5'-deoxy-5-fluorouridine monophosphate. It is a prodrug, which is activated in the body to release 5-FU and inhibits the growth of cancer cells. 5'-Deoxy-5-fluorocytidine has been shown to be effective against metastatic colorectal cancer in humans and resistant breast cancer in mice. The drug can also be used as an oral prodrug for 5-FU, which has a wide therapeutic index and low toxicity. Studies have shown that it selectively inhibits proliferation of solid tumours through inhibition of protein synthesis and cell division. The drug also has antiangiogenic effects, which are thought to contribute to its antitumor activity.Formule :C9H12FN3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :245.21 g/mol2',5'-Dideoxyuridine
CAS :2',5'-Dideoxyuridine is a synthetic nucleoside analog derived from uridine, one of the four standard nucleosides found in RNA. It is chemically modified by the removal of hydroxyl (–OH) groups at the 2' and 5' positions of the sugar, altering its ability to participate in RNA or DNA chain formation.
Formule :C9H12N2O4Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :212.21 g/mol9-(b-D-Arabinofuranosyl)adenine
CAS :9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a novel nucleoside that has been shown to inhibit the growth of cancer cells in vitro. It is an analogue of cytidine and inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This drug also inhibits the synthesis of viral RNA in cells infected with human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV-1). N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a phosphoramidite that is synthesized from 2,4,6-trichlorobenzoyl chloride, 5'-O-[(N,N-diisopropFormule :C50H51N4O8PS2Degré de pureté :Min. 95%Masse moléculaire :931.07 g/mol5'-O-Benzyl-D3-thymidine 3'-CE phosphoramidite
Produit contrôlé5'-O-Benzyl-D3-thymidine 3'-CE phosphoramidite is a novel 5'-O-benzyl modified nucleoside. It has antiviral, anticancer and monophosphate properties. It is also an activator of the diphosphate moiety and has been used in DNA synthesis and in the preparation of oligonucleotides. This compound has been shown to be an efficient inhibitor of HIV reverse transcriptase and human T cell leukemia virus type 1 (HTLV-1) replication. 5'-O-Benzyl-D3-thymidine 3'-CE phosphoramidite is an analogue of thymidine 3'-CMP that has been synthesized with a benzyl group on the 5' position.Formule :C26H34N4O6PD3Degré de pureté :Min. 95%Masse moléculaire :535.6 g/mol1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is an antiviral agent that belongs to the class of monophosphate deoxyribonucleosides. It is a novel compound that has been shown to be an activator of high purity and quality. 1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is synthesized from modified ribonucleosides and phosphoramidites. The antiviral activity of this drug against DNA viruses (e.g., herpes, adenovirus) and RNA viruses (e.g., influenza virus) has been shown in vitro and in vivo. In addition, 1-(2-C-Methyl-b--D--ribofuranosyl)-5--nitropyridine--2(1H)--Degré de pureté :Min. 95%2'-Deoxy-N2-DMF-5'-O-DMT-guanosine
CAS :2'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a monophosphate nucleoside that has antiviral, anticancer, and high purity properties. It is synthesized by the phosphoramidite method from 2'-deoxy-N2-DMF and 5'-O-DMT guanosine. This compound has been shown to inhibit the growth of human cancer cells in vitro and in vivo. It also inhibits HIV replication in vitro and is not toxic to normal cells.Formule :C34H36N6O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :624.7 g/molO2-3'-anhydro-β-D-fructofuranosyluracil
O2-3'-anhydro-beta-D-fructofuranosyluracil is a novel nucleoside analogue that has antiviral and anticancer properties. It is synthesized by the reaction of beta-D-fructofuranosyluracil with phosphoramidites. The product is purified by HPLC and characterized by IR spectroscopy, UV spectroscopy, and mass spectrometry.Degré de pureté :Min. 95%1-Methylpseudouridine
CAS :1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).Formule :C10H14N2O6Degré de pureté :Min. 98.0 Area-%Masse moléculaire :258.23 g/molRef: 3D-M-4320
-Unit-ggÀ demander1gÀ demander5gÀ demander250mgÀ demander500mgÀ demander2500mgÀ demander2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt
2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be active against herpes simplex virus type 1 and cytomegalovirus in cell culture. It also inhibits the replication of human immunodeficiency virus type 1 in cell culture. 2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a phosphoramidite nucleoside analog that can be used as an activator for DNA synthesis. It can also serve as a building block for the synthesis of deoxyribonucleosides and ribonucleosides.Degré de pureté :Min. 95%Morpholino T monomer
CAS :Morpholino T is a modified nucleoside amidite used to prepare morpholino oligomers
Formule :C31H34ClN4O5PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :609.05 g/mol2'-C-Methylguanosine 5'-diphosphate triethylammonium salt
2'-C-Methylguanosine 5'-diphosphate triethylammonium salt is a synthetic nucleotide analog for use in researchFormule :C11H16N5O11P2·C18H45N3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :759.79 g/mol3'-Amino-3'-deoxyadenosine
CAS :3'-Amino-3'-deoxyadenosine, also known as spalgomycin, is a natural enediyne antibiotic with potent antibacterial and, more notably, antitumor activity observed in research settings. Its primary use is as a tool to study the mechanisms of enediyne-mediated DNA damage and as a lead compound in the search for novel anticancer therapeutics.Formule :C10H14N6O3Couleur et forme :White Off-White PowderMasse moléculaire :266.26 g/molN6-Benzoyl-5'-O-benzoyl-2'-deoxyadenosine
CAS :N6-Benzoyl-5'-O-benzoyl-2'-deoxyadenosine is an antiviral and anticancer compound. It has been shown to be active against a number of viruses, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1, and influenza A virus. It also inhibits DNA polymerase α and β by competitive inhibition, preventing the incorporation of ribonucleotides into DNA. This compound may be used for the treatment of AIDS or as a cytostatic agent for the treatment of leukemia or lymphoma.Formule :C24H21N5O5Degré de pureté :Min. 95%Masse moléculaire :459.47 g/molGuanosine 5'-O-(2-thiodiphosphate) trilithium salt
CAS :Guanosine 5'-O-(2-thiodiphosphate) trilithium salt (GTPTS) is a membrane-permeable molecule that hyperpolarizes cells by inhibiting the movement of ions through the cell membrane. GTPTS is activated by extracellular calcium and potassium ions, which are involved in signal transduction pathways. It has been shown to inhibit the release of neurotransmitters, such as acetylcholine, dopamine, serotonin, and norepinephrine. GTPTS also blocks voltage-gated sodium channels, which leads to a reduction in neuronal excitability. The drug has been shown to have analgesic effects in animal models of pain and can be used to treat chronic pain due to nerve damage.Formule :C10H12Li3N5O10P2SDegré de pureté :Min. 85 Area-%Couleur et forme :PowderMasse moléculaire :477.06 g/molCytidine
CAS :Cytidine is a pyrimidine nucleoside that is important in the synthesis of RNA and DNA. Cytidine deaminase is an enzyme that catalyzes the conversion of cytidine to uridine. Cytidine deaminase has been shown to be inhibited by its substrate, cytidine, and by other compounds that are structurally similar to cytidine such as uracil, thymine, and guanine. Cytidine deaminase has been shown to have a role in the development of autoimmune diseases and HIV infection. This enzyme also has an important role in the polymerization of DNA during replication. Cytidine can be used for transfection experiments and to inhibit viral replication.Formule :C9H13N3O5Degré de pureté :Min. 99 Area-%Masse moléculaire :243.22 g/mol5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine
5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is a modified nucleoside that has been used as an anticancer agent and antiviral and antifungal agent. It has been shown to inhibit the growth of tumor cells in animal models by inhibiting DNA synthesis and repair. 5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is also able to bind to RNA with high affinity, making it a potential candidate for use as an antiviral agent against HIV. This compound does not occur naturally in cells and can be synthesized from other nucleosides.Formule :C15H24N2O5SiDegré de pureté :Min. 95%Masse moléculaire :340.45 g/mol3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine
CAS :3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine is an antiviral drug. It is a modified nucleoside with phosphoramidite and azido groups. This product can be used as an activator for DNA synthesis, in anticancer drug development, as well as in the treatment of HIV. 3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine has been shown to inhibit the growth of human tumor cells by inhibiting protein synthesis and enhancing the production of reactive oxygen species (ROS). It also inhibits the activity of ribonucleotide reductase, which is a critical enzyme for DNA synthesis.Degré de pureté :Min. 95%5-Fluorocytosine
CAS :Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.Formule :C4H4FN3ODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :129.09 g/mol5'-O-DMT-2'-O-methyl-5-methyluridine
CAS :5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside that is used in the synthesis of DNA. It is an anticancer drug and antiviral agent. 5'-O-DMT-2'-O-methyl-5-methyluridine has been shown to inhibit the growth of leukemia cells, even when they are resistant to other drugs. It also inhibits certain viruses, such as herpes simplex virus type 1 (HSV1), by preventing viral replication and inhibiting protein synthesis. This nucleoside is synthesized from 5'-O-DMT and 2'-O-methylcytosine.Formule :C32H34N2O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :574.64 g/molN4-Benzoyl-5'-O-DMT-5-methylcytidine
CAS :N4-Benzoyl-5'-O-DMT-5-methylcytidine is a deoxyribonucleoside that has been modified to make it resistant to nucleases. N4-Benzoyl-5'-O-DMT-5-methylcytidine is an antiviral agent, which inhibits the synthesis of viral DNA by inhibiting the activity of viral DNA polymerase. It also acts as an activator for cellular DNA polymerases and phosphoramidites. The drug can be used in the treatment of HIV and other retroviruses, herpes viruses, and certain types of cancer.Formule :C38H37N3O8Degré de pureté :Min. 95%Couleur et forme :White SolidMasse moléculaire :663.73 g/mol2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate
CAS :2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate is a chemical substance that is used as an anticancer and antiviral agent. It has been demonstrated to inhibit the proliferation of tumor cells in vitro and in vivo, and to deplete tumor cell lines of the enzyme ribonucleotide reductase, which is essential for DNA synthesis. The compound also inhibits the synthesis of viral nucleic acid. 2MMAP has a novel chemical structure that includes a methyl group attached to one nitrogen atom. This modification increases its affinity for DNA and RNA molecules by binding to the phosphate groups on these molecules.Formule :C5H7N3OS·H2ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :175.21 g/mol1-Methyl-2'-O-methylinosine
CAS :1-Methyl-2'-O-methylinosine is a nucleoside that is naturally found in RNA. It is the methylated form of inosine, which is a nonessential amino acid and purine nucleotide. 1-Methyl-2'-O-methylinosine's chemical name is β--D--ribofuranosyl-(1'→2')--N--(6-fluoro-3-indoxyl)glycinamide monohydrochloride. This nucleoside has been researched for its potential use as an indexing tool for phylogenetic research of DNA and RNA. 1-Methyl-2'-O-methylinosine has also been shown to be structurally similar to other nucleic acids and has been classified as a nucleoside.Formule :C12H16N4O5Degré de pureté :Min. 95%Masse moléculaire :296.28 g/molAdenosine 5′-phosphosulfate triethylammonium salt
Adenosine 5′-phosphosulfate triethylammonium salt serves as a donor of sulfate groups in biochemical processes, such as in the synthesis of sulfate esters. The triethylammonium salt form improves the solubility and stability of the compound, making it useful in laboratory applications involving enzymatic assays and the synthesis of sulfated biomolecules.
Formule :C10H14N5O10PS·xC6H15NDegré de pureté :Min. 98.0 Area-%Couleur et forme :PowderMasse moléculaire :427.29 g/mol5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine
5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is a novel synthetic nucleoside with antiviral and antitumor activities. It has been shown to inhibit the activity of the HIV virus by preventing DNA replication. 5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also inhibits the synthesis of RNA and proteins, which can lead to cell death. The compound's high purity and quality are ensured by its CAS number.Formule :C27H31IN4O3SiDegré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :614.55 g/mol5'-Azido-5'-deoxythymidine
CAS :5'-Azido-5'-deoxythymidine is a synthetic analogue of thymidine. The compound has been synthesised and fluorescently labelled with ferrocene. 5'-Azido-5'-deoxythymidine is not cytotoxic to cancer cells, but it is shown to be an effective inhibitor of DNA synthesis by binding to the enzyme DNA polymerase. This causes a decrease in the rate of DNA synthesis and thus inhibits cancer cell growth.Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/mol3'-Azido-N4-benzoyl-2',3'-dideoxycytidine
CAS :3'-Azido-N4-benzoyl-2',3'-dideoxycytidine is a novel nucleoside analog with antiviral and anticancer activities. It is used for the treatment of HIV, hepatitis B and C, herpes, and influenza. 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine has been shown to inhibit the proliferation of cells in culture and to induce apoptosis in various cancer cell lines.
The synthesis of 3'-azido-N4-benzoyl-2',3'-dideoxycytidine starts with the condensation of 4-(hydroxymethyl)phenylacetic acid (1) with 2,6-dichloroisonicotinic acid chloride (2) in the presence of triethylamine to give 4-(hydroxymethyl)phenylacetic acid chloride (3). The N4 benzoylFormule :C16H16N6O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :356.34 g/molN3-Methyl-2’-O-(2-methoxyethyl)uridine
CAS :N3-Methyl-2’-O-(2-methoxyethyl)uridine is a modified nucleoside that is synthesized from deoxyribonucleosides and ribonucleosides. It has antiviral, anticancer, and antifungal properties. N3-Methyl-2’-O-(2-methoxyethyl)uridine has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. This drug also inhibits the growth of human cancer cells in vitro and has been shown to be active against breast cancer cells. N3-Methyl-2’-O-(2-methoxyethyl)uridine is phosphorylated by cellular enzymes to form its active form, which binds to the viral reverse transcriptase enzyme and prevents DNA synthesis.Formule :C13H20N2O7Degré de pureté :Min. 95%Masse moléculaire :316.31 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is a novel modified nucleoside. It is an antiviral and anticancer agent that has been shown to inhibit the replication of DNA in vitro. It also inhibits the synthesis of RNA and protein, which may contribute to its anti-cancer properties. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is synthesized from 2,6,8 trichloroquinoline and 2,3,4 trimethoxybenzaldehyde via a novel process with high purity.Formule :C51H62N7O6PSiDegré de pureté :Min. 95%Masse moléculaire :928.17 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt
CAS :Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.Formule :C10H10BrN5O6P·NaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :430.08 g/mol3'-Deoxy-3'-fluoroadenosine
CAS :3'-Deoxy-3'-fluoroadenosine is a potent inhibitor of the phosphodiesterase enzyme, which is an important component of many different cellular processes. It has been shown to inhibit the activity of phosphodiesterase in cell culture and in serum alanine. 3'-Deoxy-3'-fluoroadenosine also inhibits the synthesis of uridine triphosphate, which is required for DNA replication and protein synthesis. The acid complex form has potent inhibition properties against viruses such as alphaviruses, and it also inhibits transport of nucleic acids into cells. 3'-Deoxy-3'-fluoroadenosine can act as an analog to adenosine and may be used to treat viral infections such as HIV or herpes simplex virus.Formule :C10H12FN5O3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :269.23 g/mol2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine
2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine is a novel nucleoside analog that belongs to the group of cytidine analogs. It has antiviral activity, which is due to its ability to inhibit viral replication by disrupting the synthesis of viral RNA. This drug is an activator and can be used for cancer treatment. 2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine binds to ribonucleosides and deoxyribonucleosides, preventing their incorporation into DNA or RNA. It also inhibits the biosynthesis of RNA and DNA, which leads to cell death in tumor cells.Degré de pureté :Min. 95%2'-Deoxy-5'-O-pixylinosine
2'-Deoxy-5'-O-pixylinosine is a nucleoside that is structurally similar to the natural nucleosides. It is modified with an o-pixyl group at the 2' position of the sugar moiety and contains a phosphate group at the 5' position of the sugar moiety. 2'-Deoxy-5'-O-pixylinosine has antiviral, anticancer, and high purity properties due to its ability to inhibit viral DNA polymerases. This compound has been shown to be active against a broad spectrum of viruses including HIV and herpes simplex virus types 1 and 2 (HSV1 and HSV2). This compound is also able to inhibit tumor growth in vitro.Formule :C30H26N4O4Degré de pureté :Min. 95%Masse moléculaire :506.57 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine
CAS :2'-O-(2-methoxyethyl)-5-methylcytidine is a novel antiviral monophosphate nucleoside that has been shown to be a potent activator of the immune system. It was synthesized by modifying a deoxyribonucleoside and phosphoramidite. 2'-O-(2-methoxyethyl)-5-methylcytidine is synthetic and can be used as an anticancer drug for the treatment of leukemia, lymphoma, and other cancers. This compound has also shown efficacy in treating diphosphate nucleotides such as HIV-1 reverse transcriptase, which is an enzyme crucial for viral replication.Formule :C13H21N3O6Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :315.32 g/mol(R)-N-(2,3-Dihydro-1H-indenyl)adenosine
CAS :(R)-N-(2,3-Dihydro-1H-indenyl)adenosine is a purine nucleoside with the attachment of a 2,3-dihydro-1H-indenyl group via a nitrogen atom. This adenosine-based product can be used for research purposesFormule :C19H21N5O4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :383.4 g/molCyclopentenyl cytosine 5'-triphosphate sodium salt
Cyclopentenyl cytosine 5'-triphosphate sodium salt is a synthetic, activator diphosphate. It is used as a phosphoramidite in the synthesis of DNA and RNA. Cyclopentenyl cytosine 5'-triphosphate sodium salt has been shown to have anticancer and antiviral properties.Degré de pureté :Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS :N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer potential. It is a modified nucleoside that contains an acetyl group at the 4' position. The 3'-OH group has been replaced by a tertiary butyldimethylsilyl group, which renders the compound resistant to deamination by nucleases. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also shows high purity and high quality.Formule :C47H64N5O9PSiDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :902.11 g/molN-Cbz gemcitabine
CAS :N-Cbz gemcitabine is a novel nucleoside analog that is chemically modified to be activated by enzymes in the cell. It has been shown to have high purity and high quality. In addition, N-Cbz gemcitabine is an anticancer drug that is most effective against cells with a low number of nucleotides per cell. This drug has shown antiviral properties and is used for the treatment of HIV/AIDS patients.Formule :C17H17F2N3O6Degré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :397.33 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)thymine
CAS :1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside analog. This compound contains a thymine base, a 2'-fluoro-β-D-arabinofuranose sugar, which alters biological stability and function and benzoyl protecting groups at the 3' and 5' positions, commonly used in nucleoside synthesis to control selective modifications.Formule :C24H21FN2O7Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :468.43 g/mol3'-Deoxy-N-dimethylformamidine- 5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG
3'-Deoxy-N-dimethylformamidine-5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG is an anticancer, antiviral, and modified nucleoside. It is a novel monophosphate nucleoside that can be used in the synthesis of DNA or RNA. 3'-Deoxy-N-dimethylformamidine is a synthetic phosphoramidite that is activated with triethylamine and reacts with 5'--DMT--guanosine to yield a novel nucleoside. The compound has high purity and high quality.Degré de pureté :Min. 95%Adenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution
Adenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution is a novel nucleoside that is synthesized from the corresponding phosphoramidites. This compound is an activator of DNA synthesis in mammalian cells and a potent inhibitor of viral replication. It has antiviral activity against HIV, herpes, and influenza viruses. The molecule can be modified to include different substituents such as fluoro, bromo, or chloro groups and has been shown to have anticancer activity.Formule :C24H27BF2N8Na3O13P3SDegré de pureté :Min. 95%Masse moléculaire :878.28 g/molAcetoacetyl coenzyme A lithium salt
CAS :Acetoacetyl coenzyme A lithium salt is a novel phosphoramidite building block. It's a modified nucleoside that can be used in the synthesis of oligonucleotides and DNA. Acetoacetyl coenzyme A lithium salt has antiviral, anticancer, and antifungal activities.Formule :C25H36N7O18P3SLi4·5H2ODegré de pureté :Min. 96 Area-%Couleur et forme :PowderMasse moléculaire :965.42 g/mol5-Methoxycarbonylmethyl-2-thiouridine
CAS :Nucleoside functionalised on the baseFormule :C12H16N2O7SDegré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :332.33 g/mol4-Chloro-7-(2C-methyl-3,5-bis-O-(4-methylbenzoyl)-b-D- ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS :4-Chloro-7-(2C-methyl-3,5-bis-O-(4-methylbenzoyl)-b-D ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a monophosphate nucleotide analog. It is structurally related to the natural nucleoside 2′,3′ dideoxyadenosine. It can be used as an antiviral agent and has also been shown to have possible use in the treatment of HIV infections. 4C7DPP is a novel compound that is synthesized from phosphoramidites and activated with a novel activator. The purity of this compound is high and the quality is very good. CAS No. 1338072-45-9Degré de pureté :Min. 95%Morpholino C monomer
CAS :Morpholino C monomer is a nucleoside amidite used to prepare morpholino oligomers
Formule :C37H37ClN5O5PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :698.15 g/mol2-Methoxy-9-(b-D-ribofuranosyl)purine
CAS :2-Methoxy-9-(b-D-ribofuranosyl)purine (2MeO) is a nucleoside that is structurally similar to adenosine. It has antiviral and anticancer activities, as well as the ability to activate phosphoramidites. The 2MeO molecule consists of a modified 9-mer ribofuranose phosphate, which can be synthesized from 2-deoxyribofuranose phosphate by selective oxidation. 2MeO has been shown to inhibit the growth of tumor cells in vitro and in vivo, and also inhibits the replication of DNA and RNA viruses. This drug is considered novel because it does not exist naturally in any organism.Degré de pureté :Min. 95%9-(b-D-Arabinofuranosyl)isoguanine
CAS :9-(b-D-Arabinofuranosyl)isoguanine is a modified nucleoside that has antiviral activity. It is synthesized by substituting the 2'-hydroxyl group of deoxyribose with an arabinofuranose, which can be phosphorylated to form 9-(b-D-arabinofuranosyl)isoguanine 5'-monophosphate. This novel antiviral agent inhibits the synthesis of viral DNA and RNA, and is effective against a wide range of viruses in vitro. The drug was shown to have anticancer activities in animal models and has been patented for use as a chemotherapeutic agent against leukemia, lymphoma, and other cancers.Formule :C10H13N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :283.25 g/molN2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine
N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine is a nucleoside that is modified with a chlorine group. The modification of the nucleoside may enhance its anticancer activity. N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2 aminopurine has been shown to inhibit the growth of virus and cancer cells by inhibiting DNA synthesis. It has also been shown to induce apoptosis in human leukemia cells.Formule :C21H30ClN5O9Degré de pureté :Min. 95%Couleur et forme :White to beige solid.Masse moléculaire :531.94 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite
CAS :The 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is an oligomer with a modified nucleoside. The modification of the nucleoside has been shown to be more efficient than other modifications, such as fluorine or bromine substitutions. This product is used in the synthesis of DNA and RNA oligomers. The coupling efficiency is high and can be used for ligand binding studies.Formule :C50H68N7O9PSiDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :970.18 g/mol5-Hydroxymethylcytidine
CAS :5-Hydroxymethylcytidine is a nucleoside that has been shown to inhibit the activity of RNA polymerase by forming hydrogen bonds with the enzyme. It is used in vitro to study the role of messenger RNA in regulating gene expression, and also as a probe for transcriptase activity. 5-Hydroxymethylcytidine has also been shown to have a biological function in solid tumours and may be an analytical method for detecting cancer.Formule :C10H15N3O6Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :273.24 g/mol
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