Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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Trifluorothymidine
CAS :Treats herpes-associated keratitis and keratoconjunctivitis; antineoplasticFormule :C10H11F3N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :296.2 g/molUridine 5'-monophosphate
CAS :Uridine 5'-monophosphate (UMP) is a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. UMP has been shown to inhibit the protein synthesis of cells by inhibiting the enzyme activities of DNA polymerase and RNA polymerase. It also inhibits the synthesis of p2y receptors, which are involved in cell proliferation and differentiation. Further studies suggest that UMP may be an effective anti-inflammatory agent due to its ability to decrease prostaglandin production.Formule :C9H13N2O9PDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :324.18 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a novel modified ribonucleoside that has been synthesized to mimic the natural nucleotide. It has been shown to activate DNA synthesis, inhibit cancer cell division and proliferation, and inhibit viral replication. 2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-5'-O-MMTguanosine 3'-CE phosphoramidite is a monophosphate nucleotide with an anticancer activity. It has also showed antiviral effects against HIV and Hepatitis B virus. This novel modified ribonucleoside is highly pure and can be used for the synthesis of high quality DNA, RNA, or phosphoramidites.Formule :C49H66N7O8PSiDegré de pureté :Min. 95%Masse moléculaire :940.17 g/molb-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium)
CAS :b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium), or NADPH, is involved in redox reactions, where it acts as an electron donor. NADPH is essential for anabolic reactions, such as lipid and cholesterol biosynthesis, and fatty acid chain elongation. It also plays a significant role in antioxidation mechanisms, protecting cells from oxidative stress by neutralizing reactive oxygen species (ROS) and regenerating antioxidants like glutathioneFormule :C21H30N7O17P3·4C6H13NDegré de pureté :Min. 90 Area-%Couleur et forme :Slightly Yellow PowderMasse moléculaire :1,142.12 g/mol5'-O-p-Anisoyl-2,2'-anhydrouridine
5'-O-p-Anisoyl-2,2'-anhydrouridine is a novel nucleoside. It is an activator of ribonucleosides and deoxyribonucleosides. This compound has antiviral activity against HIV and DNA synthesis inhibitory activity against cancer cells. 5'-O-p-Anisoyl-2,2'-anhydrouridine is also a modified nucleoside that can be used for the synthesis of phosphoramidites for the chemical synthesis of oligodeoxynucleotides (ODN).Formule :C17H16N2O7Degré de pureté :Min. 95%Masse moléculaire :360.32 g/mol3-Deaza-2'-O-methyluridine
CAS :3-Deaza-2'-O-methyluridine is a nucleoside that is used as an antiviral agent and in the treatment of leukemia. It has been shown to inhibit the growth of L1210 cells in a dose-dependent manner. 3-Deaza-2'-O-methyluridine also inhibits the synthesis of DNA, RNA, and proteins. The compound is eliminated by renal excretion with a plasma elimination half life of 9 hours. This drug can be administered intramuscularly or intravenously at a dosage of 10 mg/kg every 8 hours, but should not be given more than 5 days without interruption due to accumulation in tissues.
Formule :C11H15NO6Degré de pureté :Min. 95%Masse moléculaire :257.24 g/mol5'-O-DMT-α-thymidine
5'-O-DMT-a-thymidine is a modified nucleoside that is used in the synthesis of DNA and RNA. This product is a high quality and pure monophosphate, which has been modified to reduce its potential for activation by phosphatases. It is suitable for use in anticancer drugs and antiviral agents.
Formule :C31H32N2O7Degré de pureté :Min. 95%Masse moléculaire :544.6 g/mol2',3',5'-Tri-O-benzoyl-N6-benzyl-2'-C-methyladenosine
CAS :2',3',5'-Tri-O-benzoyl-N6-benzyl-2'-C-methyladenosine is an adenosine analog for potential use in research into antiviral drug development or nucleoside analogs.Formule :C39H33N5O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :683.71 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine
CAS :2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.Degré de pureté :Min. 95%3'-Deoxythymidine
CAS :3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.Formule :C10H14N2O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :226.23 g/mol3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine
CAS :Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this pageDegré de pureté :Min. 95%N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt
CAS :N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is a novel modified nucleoside with anticancer activity. The compound is a monophosphate, which activates DNA and RNA synthesis. This agent also has antiviral and antifungal effects. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt is synthesized from diphosphate and deoxyribonucleosides. It was first patented in 1979 and has been approved by the US Food and Drug Administration (FDA) for use as a pharmaceutical agent. N-Succinyl-5-aminoimidazole-4-carboxamide ribose disodium salt can be used to produce phosphoramidites, which are synthetic DNA building blocks that are used in the production of DNA and RNA synthesis.Formule :C13H16N4O9Na2Degré de pureté :Min. 95 Area-%Couleur et forme :Off-White PowderMasse moléculaire :418.27 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS :N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.
Formule :C20H21N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :411.41 g/mol2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine
CAS :2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methoxyuridine is a modified nucleoside that is used as an anticancer drug. It is synthesized from 2’,3’,5’triphosphate and 2’C-methyl-5-methoxyuridine. This compound is used to treat leukemia and other cancers by inhibiting the synthesis of DNA. Inhibiting DNA synthesis prevents the reproduction of cancer cells. The chemical structure of this compound was first published in 2007.Degré de pureté :Min. 95%2'-Deoxyadenosine 3'-O-L-valinyl ester
2'-Deoxyadenosine 3'-O-L-valinyl ester is a novel nucleoside phosphoramidite that is synthesized by activating the 2'-deoxyribose phosphate with an L-valyl chloride. This synthetic nucleoside analog can be used as a substitute for dATP in DNA synthesis and has antiviral as well as anticancer activities.Degré de pureté :Min. 95%5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite
5'-O-tert-Butyldimethsilyl-2'-Deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is a modified nucleoside that is synthesized by reacting 5'-O-tert-butyldimethylsilyl guanosine with 2'-deoxyisobutyryl chloride in the presence of triethylamine. The resulting 5'-O-tert-butyldimethylsilyl-2'-deoxyisobutyrylguanosine 3'-CE phosphoramidite has been shown to be cytotoxic to tumor cells without affecting normal cells.Formule :C29H50N7O6PSiDegré de pureté :Min. 95%Masse moléculaire :651.82 g/mol1-(b-L-Threonyl)uracil
1-(b-L-Threonyl)uracil is a novel anticancer drug that has been synthesized with the aim of increasing the efficacy of DNA synthesis. The incorporation of this nucleoside in the DNA chain prevents the formation of ribonuclesides, which are inhibitory to DNA synthesis. It also inhibits viral replication and can be used as a treatment for HIV infection. 1-(b-L-Threonyl)uracil is synthesized by reacting b-L-threonyl chloride with uracil in the presence of a base and a catalytic amount of thiourea. This product is used in biotechnology as an activator for phosphoramidites and modified nucleosides.Degré de pureté :Min. 95%3’-Azido-3’-deoxy-b-L-adenosine
CAS :3’-Azido-3’-deoxy-b-L-adenosine is a novel nucleoside that has been synthesized to be used as an antiviral agent. It is phosphorylated, which allows it to be activated by adenosine kinase, and is thus able to inhibit viral replication and spread. 3’-Azido-3’-deoxy-b-L-adenosine is effective against various viruses, including HIV, herpes simplex virus type 1 (HSV1), and hepatitis C virus (HCV). This nucleoside also has anticancer activity due to its ability to inhibit the synthesis of DNA and RNA. It has been modified from the natural nucleosides with the addition of a 2′,3′ azido group at the 3 position on the ribose sugar. The modification prevents viral resistance because it does not require activation by cellular kinases or phosphorylation in order to be active.Degré de pureté :Min. 95%3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine
CAS :Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this pageDegré de pureté :Min. 95%N6-Benzoyl-2'-C-methyladenosine
N6-Benzoyl-2'-C-methyladenosine is synthetic and has antiviral properties. It is a nucleoside that belongs to the group of modified nucleosides. This compound can be used as an activator for DNA synthesis and as a novel monophosphate, diphosphate, or triphosphate. N6-Benzoyl-2'-C-methyladenosine is also available in high purity, with CAS No., and at a competitive price.Degré de pureté :Min. 95%
