Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.763 produits)
- Apoptose(6.205 produits)
- Cycle cellulaire/point de contrôle(4.812 produits)
- Chromatine/Épigénétique(2.553 produits)
- Signalisation du cytosquelette(1.520 produits)
- Altération de l'ADN/réparation de l'ADN(2.906 produits)
- Endocrinologie/Hormones(3.703 produits)
- Enzyme(3.671 produits)
- GPCR/G-Protéine(8.965 produits)
- Immunologie et Inflammation(3.749 produits)
- Virus de la grippe(297 produits)
- Signalisation JAK/STAT(414 produits)
- Signalisation MAPK(1.244 produits)
- Transporteur membranaire/Canal ionique(3.118 produits)
- Métabolisme(10.123 produits)
- Microbiologie/Virologie(7.569 produits)
- Neuroscience(10.314 produits)
- Autres inhibiteurs(35.804 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.411 produits)
- Protéases/Protéasome(1.681 produits)
- Cellules souche et Dérivés(752 produits)
- Tyrosine Kinase/Adaptateurs(1.947 produits)
- Ubiquitination(1.716 produits)
Affichez 16 plus de sous-catégories
66604 produits trouvés pour "Inhibiteurs"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
AZ0108
CAS :AZ0108, an oral PARP1,2,6 inhibitor, selectively blocks centrosome clustering, is viable for in vivo studies, and doesn't inhibit PARP3/TNKS1.Formule :C24H20F4N6O2Couleur et forme :SolidMasse moléculaire :500.45HIV-1 inhibitor-14
HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.Formule :C29H32N6O4SCouleur et forme :SolidMasse moléculaire :560.67BMS-901715
CAS :BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).Formule :C22H28N10ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.52GPR81 agonist 2
CAS :GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively.Formule :C26H27ClN6O5S2Couleur et forme :SolidMasse moléculaire :603.11AD012
AD012, a dual cACE/NEP inhibitor, leverages lenopril-tryptophan for potential anti-hypertensive and cardioprotective benefits.Formule :C25H32N2O6Couleur et forme :SolidMasse moléculaire :456.53Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formule :C22H28N6OCouleur et forme :SolidMasse moléculaire :392.5MRTX849 ethoxypropanoic acid
CAS :MRTX849 is a KRAS G12C ligand and PROTAC linker for creating potent LC-2, degrading KRAS G12C with DC50 of 0.25-0.76 μM.Formule :C37H43ClFN7O5Couleur et forme :SolidMasse moléculaire :720.24Antimalarial agent 9
Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.Formule :C28H32BrN3O2Couleur et forme :SolidMasse moléculaire :522.48PKCiota-IN-1
CAS :PKCiota-IN-1: Strong PKC-ι inhibitor (IC50=2.7 nM); also blocks PKC-α/ε (IC50s=45/450 nM).Formule :C25H22FN5OCouleur et forme :SolidMasse moléculaire :427.473'-Hydroxy Repaglinide
CAS :'3'-Hydroxy Repaglinide, a CYP2C8 metabolite of Repaglinide, treats type II diabetes.Formule :C27H36N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.59Cilobamine (free base)
CAS :Cilobamine: a stimulant antidepressant, inhibits norepinephrine-dopamine reuptake, based on dichloroisoprenaline structure.Formule :C17H23Cl2NOCouleur et forme :SolidMasse moléculaire :328.28C108297
CAS :C108297: glucocorticoid modulator, combats diet obesity/inflammation, reduces appetite/lipid storage, boosts fat burn.Formule :C30H36FN3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.69Glutaminyl Cyclase Inhibitor 3
CAS :Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formule :C24H32N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.61CB30865
CAS :CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.Formule :C26H22BrN5O2Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :516.39RET-IN-11
RET-IN-11 selectively inhibits RET (IC50: 6.20 nM), promotes apoptosis, and hinders cell proliferation and migration.Formule :C27H30FN9OCouleur et forme :SolidMasse moléculaire :515.59ATX inhibitor 12
Oral ATX inhibitor 12 (IC50: 1.72 nM) at 60 mg/kg prevents lung damage in C57Bl/6J mice.
Formule :C30H34FN5O2Couleur et forme :SolidMasse moléculaire :515.62DJT06001
CAS :DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.Formule :C21H20ClN3O5SCouleur et forme :SolidMasse moléculaire :461.92PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Formule :C22H29N5O2Couleur et forme :SolidMasse moléculaire :395.5Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37AL-6556
CAS :AL-6556 is a prostaglandin DP receptor agonist.Formule :C20H33ClO5Couleur et forme :SolidMasse moléculaire :388.93C-11
CAS :C-11 is a tubulin inhibitor and acts as an ADC cytotoxin with cytotoxicity for carcinoma cell lines.Formule :C38H58N6O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :742.97Furametpyr
CAS :Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formule :C17H20ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.81Ici D1542
CAS :Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Formule :C25H30N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.51SHR2415
SHR2415: Potent, selective ERK1/2 inhibitor, oral; ERK1 IC50: 2.8 nM, ERK2 IC50: 5.9 nM; effective in Colo205 (IC50: 44.6 nM), for cancer research.Formule :C23H22ClN7O2Couleur et forme :SolidMasse moléculaire :463.92ONO-5334
CAS :ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).Formule :C21H34N4O4SDegré de pureté :98.22% - 99.60%Couleur et forme :SolidMasse moléculaire :438.58JBJ-02-112-05
CAS :JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC 50 of 15 nM for EGFR L858R/T790M [1].Formule :C27H20N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.54WF-47-JS03
WF-47-JS03: RET kinase inhibitor, crosses blood-brain barrier, 500x more selective for KDR, IC50: 1.7 nM in Ba/F3 cells, 5.3 nM in LC-2/ad lung cancer cells.
Formule :C30H38N6O2Couleur et forme :SolidMasse moléculaire :514.66Bcl-2-IN-7
Bcl-2-IN-7 inhibits Bcl-2, encourages apoptosis in cancer cells, and has anti-tumor activity with various IC50 values.Formule :C24H22N4O5S2Couleur et forme :SolidMasse moléculaire :510.59Antitubercular agent-23
Antitubercular agent-23 combats Candida albicans (MIC: 1.1 μg/ml) and M. tuberculosis (MIC: 1 μg/ml).Formule :C20H22FN5O8SCouleur et forme :SolidMasse moléculaire :511.48MIF2-IN-1
MIF2-IN-1, potent inhibitor of MIF2 (IC50: 1μM), halts non-small cell lung cancer growth via MAPK pathway.Formule :C26H19F3N2O2SCouleur et forme :SolidMasse moléculaire :480.5Antiviral agent 7
Antiviral agent 7 is a peptide-based coating that kills viruses.Formule :C29H31F2N3O6Couleur et forme :SolidMasse moléculaire :555.57Soyacerebroside II
CAS :Soyacerebroside II is a Ca2+ ionophore; both I and II inhibit IL-18 in PBMCs and modulate immune responses.Formule :C40H75NO9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :714.02GLP-1R agonist 8
CAS :GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Formule :C33H32N4O5Couleur et forme :SolidMasse moléculaire :564.63GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45GLS1 Inhibitor-5
GLS1 Inhibitor-5 (24y): Selective, oral glutaminase 1 inhibitor; IC50 68 nM; induces apoptosis; anti-tumor.Couleur et forme :SolidVEGFR-2/DHFR-IN-2
VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.4SHP2-IN-9
SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.Formule :C20H20FN3O2SCouleur et forme :SolidMasse moléculaire :385.46Cemdomespib
CAS :Cemdomespib (KU-596) is a potent Hsp90 modulator with neuroprotective effects and can improve diabetic neuropathy.Formule :C24H30FNO6Couleur et forme :SolidMasse moléculaire :447.5BI-44370
CAS :BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formule :C35H47N5O6Couleur et forme :SolidMasse moléculaire :633.78P-gp modulator 1
CAS :P-gp modulator 1 is a high affinity and orally available P-glycoprotein (Pgp) modulatorFormule :C41H72N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :689.02HDAC8-IN-2
HDAC8-IN-2 (5o) inhibits both smHDAC8 and hHDAC8 with IC50s of 0.27 μM, 0.32 μM, kills schistosome larvae, and lowers egg laying.Formule :C21H16N2O5Couleur et forme :SolidMasse moléculaire :376.36CU-2010
CAS :CU-2010 is a synthetic compound that reduces blood loss and aids recovery post-cardiac surgery.Formule :C37H42N6O6SCouleur et forme :SolidMasse moléculaire :698.835-Ph-IAA-AM
5-Ph-IAA-AM, eggshell-permeable analog of 5-Ph-IAA, boosts protein degradation in embryos, useful for studying proteins in C. elegans.Formule :C19H17NO4Couleur et forme :SolidMasse moléculaire :323.34NLRP3/AIM2-IN-1
NLRP3/AIM2-IN-1 is an inhibitor of thermal sepsis (IC50 = 3.136 ± 0.7667 μM).Formule :C15H16BNO4Couleur et forme :SolidMasse moléculaire :285.1AGN-204396
CAS :AGN-204396 is an antagonist that selectively blocks the activity of prostamides (prostaglandin-ethanolamides).Formule :C32H44FN3O4Couleur et forme :SolidMasse moléculaire :553.71AP5
CAS :AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.Formule :C28H28FNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.52A25822B
CAS :A25822B is an antifungal agent.Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66Fandosentan
CAS :Fandosentan is an endothelin receptor antagonist.Formule :C25H18F3NO6SCouleur et forme :SolidMasse moléculaire :517.47SD-2590 HCl
CAS :SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.Formule :C22H26ClF3N2O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.9620S Proteasome-IN-4
CAS :20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.Formule :C20H18ClF2N3O3Couleur et forme :SolidMasse moléculaire :421.83GID4 Ligand 1
GID4 Ligand 1: cell-permeable, selective binder, IC50 5.4 μM, Kd 5.6 μM, binds in cells with EC50 558 nM, useful for PROTAC synthesis.
Formule :C28H34N4O5SCouleur et forme :SolidMasse moléculaire :538.66Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].Formule :C14H7Cl2F3N2OCouleur et forme :SolidMasse moléculaire :347.12GRP78-IN-1
GRP78-IN-1 binds to GRP78 protein, inhibits cell growth, and triggers apoptosis in breast cancer; has -8.07 kcal/mol binding energy.Formule :C21H23FO3Couleur et forme :SolidMasse moléculaire :342.4Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Formule :C27H21N5O2SCouleur et forme :SolidMasse moléculaire :479.55KRAS G12C inhibitor 15
CAS :KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .Formule :C25H21ClF2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.91EGFR/HER2-IN-4
EGFR/HER2-IN-4: oral, irreversible dual EGFR inhibitor (IC50: 0.6 nM), targets L858R/T790M mutations, potent anti-lung cancer effects in vivo.Couleur et forme :SolidTAK-915
CAS :TAK-915: potent, brain-ready PDE2A inhibitor, 0.61 nM IC50, 4100x selectivity over PDE1A.Formule :C19H18F4N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.36Rpi 856 C
CAS :Rpi 856 C is a retrovirus protease inhibitor from Streptomyces that is effective against HIV-1 and HTLV-1 proteases.Formule :C39H56N6O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :768.90EGFR-IN-35
CAS :EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.Formule :C25H24ClN7O2Couleur et forme :SolidMasse moléculaire :489.96Rafutrombopag
CAS :Rafutrombopag is a thrombopoietin (TPO) agonist.Formule :C25H22N4O5Couleur et forme :SolidMasse moléculaire :458.47LMD-A
CAS :LMD-A, also known as CCR8 antagonist LMD-A, is a CCR8 antagonist.Formule :C27H32N4O4SCouleur et forme :SolidMasse moléculaire :508.63PHGDH-IN-2
PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.Formule :C22H20N4O3SCouleur et forme :SolidMasse moléculaire :420.48IMP-321
CAS :IMP-321 is a soluble dimeric recombinant form of LAG-3 and first-in-class antigen presenting cell activator.Formule :C56H78N18O14SCouleur et forme :SolidMasse moléculaire :1259.4DENV-IN-6
CAS :DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.Formule :C23H26ClFN4OSCouleur et forme :SolidMasse moléculaire :461EZH2-IN-12
EZH2-IN-12 (Compound 5) is a potent inhibitor of EZH2, which has potential for studies of CNS malignancies.Formule :C23H23Cl2N3O3Couleur et forme :SolidMasse moléculaire :460.35(2R,3S)-Azelaprag
CAS :(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonistFormule :C25H29N7O4SDegré de pureté :97.47% - >99.99%Couleur et forme :SoildMasse moléculaire :523.61Antifungal agent 43
Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.Formule :C24H26N4Se2Couleur et forme :SolidMasse moléculaire :528.41Pim-1 kinase inhibitor 3
CAS :Pim-1 kinase inhibitor 3 (Compound H5) is a potent inhibitor of Pim-1 kinase, demonstrating an inhibitory concentration (IC50) of 35.13 nM [1].Formule :C20H25N3O2Couleur et forme :SolidMasse moléculaire :339.43Ro 31-8472
CAS :Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.Formule :C20H27N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.44Dup-714
CAS :Dup-714 is a thrombin inhibitor.Formule :C21H33BN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.33TRPV1 antagonist 3
TRPV1 antagonist 3 (7q) strongly blocks TRPV1 at 2.66 nM IC50, is selective, 60% bioavailable, and crosses the blood-brain barrier.Formule :C23H25N3OSCouleur et forme :SolidMasse moléculaire :391.53L-threo-Sphingosine C-18
CAS :L-threo-Sphingosine C-18 is a protein kinase C inhibitor.Formule :C18H37NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.49JAK3/BTK-IN-3
CAS :JAK3/BTK-IN-3: strong dual JAK3/BTK suppressor, promising for autoimmune disease research.Formule :C22H28N8OCouleur et forme :SolidMasse moléculaire :420.51LpxC-IN-10
CAS :LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.Formule :C30H31N5O3Couleur et forme :SolidMasse moléculaire :509.6Annonin VI
CAS :Annonin VI is a natural inhibitor of NADH:ubiquinone oxidoreductase.Formule :C37H66O7Couleur et forme :SolidMasse moléculaire :622.92COX-2/PI3K-IN-2
COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).Formule :C16H17N5O2Couleur et forme :SolidMasse moléculaire :311.34Gougerotin
CAS :Gougerotin is an inhibitor of protein synthesis.Formule :C16H25N7O8Couleur et forme :SolidMasse moléculaire :443.41Glucosylceramide synthase-IN-3
Glucosylceramide synthase-IN-3 (BZ1) is a potent, brain-accessible, oral GCS inhibitor with a 16 nM IC50, relevant for Gaucher's disease study.Formule :C21H20FN3O3Couleur et forme :SolidMasse moléculaire :381.4Dyrk1A/α-synuclein-IN-1
Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and α-synuclein aggregation (IC50: 10.5 μM).Formule :C20H21N5O3SCouleur et forme :SolidMasse moléculaire :411.48NLRP3-IN-4
NLRP3-IN-4 is an effective, oral NLRP3 inflammasome inhibitor with potent anti-inflammatory effects on colitis.Formule :C22H22N2O5Couleur et forme :SolidMasse moléculaire :394.42AD5075
CAS :AD5075 is a bioactive chemical.Formule :C22H20N2O5SCouleur et forme :SolidMasse moléculaire :424.47Lepidozin G
Lepidozin G blocks cancer growth (IC50=4.2-5.7μM) and triggers apoptosis in PC-3 cells via mitochondria.Formule :C30H48O4Couleur et forme :SolidMasse moléculaire :472.7c(phg-isoDGR-(NMe)k)
CAS :c (phg-isoDGR- (NMe) k) is a selective and effective α5β1-integrin ligand with IC50 of 2.9 nM.Formule :C27H41N9O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.67BI-685509
CAS :BI-685509: potent, oral sGC activator, boosts cGMP, enhances NO pathways, for CKD/DKD research.Formule :C34H38N4O5Couleur et forme :SolidMasse moléculaire :582.69RET-IN-9
CAS :RET-IN-9 is a potent RET kinase inhibitor, potentially useful for studying RET-related diseases, including lung and thyroid cancer.Formule :C26H27N9OCouleur et forme :SolidMasse moléculaire :481.55Kri 1314
CAS :Kri 1314 is a cyclohexyl-norstatine-containing dipeptide renin inhibitor which has potential for the treatment of hypertension.Formule :C38H51N5O7Couleur et forme :SolidMasse moléculaire :689.84FAK-IN-2
FAK-IN-2: potent oral FAK inhibitor, IC50 35 nM, reduces tumor growth, migration, and induces cell death.Formule :C28H31ClN8O3Couleur et forme :SolidMasse moléculaire :563.05JAK3 covalent inhibitor-1
CAS :JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus kinase 3 (JAK3), possessing an IC50 of 11 nM andFormule :C22H17FN6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.47trans-RdRP-IN-5
Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.Formule :C23H21N3O5Couleur et forme :SolidMasse moléculaire :419.43Inupadenant HCl
CAS :Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.Formule :C25H27ClF2N8O4S2Couleur et forme :SolidMasse moléculaire :641.11AM Toxin II
CAS :AM Toxin II is a Cyclic tetradepsipeptide isolated from Alternaria mali.Formule :C22H29N3O5Couleur et forme :SolidMasse moléculaire :415.49HER2-IN-7
CAS :HER2-IN-7 is a potent HER2 inhibitor with potential for researching ErbB-related diseases, especially cancer.Formule :C28H26F3N7O3Couleur et forme :SolidMasse moléculaire :565.55Topo I/COX-2-IN-1
Topo I/COX-2-IN-1: potent dual inhibitor; IC50 0.24μM (COX-2), 4.42μM (Topo I); anti-cancer; induces apoptosis, halts migration.Formule :C21H18ClFN2O3Couleur et forme :SolidMasse moléculaire :400.83CDK1-IN-3
CDK1-IN-3 is a selective inhibitor targeting CDK1 (36.8 nM), CDK2 (305.17 nM), CDK5 (369.37 nM); used in cancer research.Formule :C28H25ClF3N5O2Couleur et forme :SolidMasse moléculaire :555.98Microtubule inhibitor 2
Microtubule inhibitor 2: potent, selective, oral, induces ferroptosis, strong antitumor effect.Formule :C20H23NO7Couleur et forme :SolidMasse moléculaire :389.4TAK-024
CAS :TAK-024 is an inhibitor of platelet(IC50s of 31, 79 and 51 nM in human, monkey and guinea pig, respectively).Formule :C27H34N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.62ONO-AE1-329
CAS :ONO-AE1-329 is a novel agonist of the prostaglandin PGE2 receptor EP4.Formule :C22H30O6S2Couleur et forme :SolidMasse moléculaire :454.6PF-06462894
CAS :PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Formule :C18H23N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.39Pparδ agonist 5
Pparδ agonist 5 is a selective, orally active PPARδ agonist with an EC50 of 0.335 μM and better selectivity than GW0742.Formule :C23H21F3N2O2SCouleur et forme :SolidMasse moléculaire :446.49ARG1-IN-1
CAS :ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM.Formule :C11H21BN2O4Couleur et forme :SolidMasse moléculaire :256.11
