Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.763 produits)
- Apoptose(6.205 produits)
- Cycle cellulaire/point de contrôle(4.812 produits)
- Chromatine/Épigénétique(2.553 produits)
- Signalisation du cytosquelette(1.520 produits)
- Altération de l'ADN/réparation de l'ADN(2.906 produits)
- Endocrinologie/Hormones(3.703 produits)
- Enzyme(3.671 produits)
- GPCR/G-Protéine(8.965 produits)
- Immunologie et Inflammation(3.749 produits)
- Virus de la grippe(297 produits)
- Signalisation JAK/STAT(414 produits)
- Signalisation MAPK(1.244 produits)
- Transporteur membranaire/Canal ionique(3.118 produits)
- Métabolisme(10.123 produits)
- Microbiologie/Virologie(7.569 produits)
- Neuroscience(10.314 produits)
- Autres inhibiteurs(35.804 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.411 produits)
- Protéases/Protéasome(1.681 produits)
- Cellules souche et Dérivés(752 produits)
- Tyrosine Kinase/Adaptateurs(1.947 produits)
- Ubiquitination(1.716 produits)
Affichez 16 plus de sous-catégories
66604 produits trouvés pour "Inhibiteurs"
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TrxR-IN-2
TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.Formule :C22H22N4O4Couleur et forme :SolidMasse moléculaire :406.43Topoisomerase II inhibitor 6
Topoisomerase II inhibitor 6, a potent tryptanthrin derivative, blocks G2 phase in CCRF-CEM cells, induces DNA breaks, and may be used for cancer research.Formule :C19H18N4O2Couleur et forme :SolidMasse moléculaire :334.37CBP/p300-IN-2
CAS :CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc).Formule :C27H29F2N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.56GSK3368715 3HCl
CAS :GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81Formule :C20H41Cl3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :475.92hAChE/Aβ1-42-IN-1
CAS :Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines andFormule :C20H24N6OCouleur et forme :SolidMasse moléculaire :364.44Mepixetil
Mepixetil is a potent angiotensin II receptor antagonist[1].Formule :C12H18N2O3Couleur et forme :SolidMasse moléculaire :238.28SARS-CoV-2-IN-6
SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.Formule :C17H13ClN2O2Couleur et forme :SolidMasse moléculaire :312.75Pyridoxatin
CAS :Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.Formule :C15H21NO3Couleur et forme :SolidMasse moléculaire :263.33HIV-1 inhibitor-17
HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).Formule :C32H32N4O5SCouleur et forme :SolidMasse moléculaire :584.69HDAC6-IN-9
CAS :HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.Formule :C19H16N2O3Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :320.34GnRH-R antagonist 1
CAS :Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.Formule :C31H28F5N7O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :721.65IRAK4-IN-15
CAS :IRAK4-IN-15: selective IRAK4 inhibitor, IC50 0.002 μM, good PK, low clearance, synergizes with Acalabrutinib in MyD88/CD79 mutant ABC-DLBCL.Formule :C25H29FN10Couleur et forme :SolidMasse moléculaire :488.56B-3852
CAS :B-3852 is a Bradykinin inhibitor.Formule :C55H74F3N15O11Couleur et forme :SolidMasse moléculaire :1178.27CGC 11150
CAS :CGC 11150 is a polyamine analogue inhibit tumor growth in vitro and in vivo.Formule :C40H100Cl10N10Couleur et forme :SolidMasse moléculaire :1075.82D-473
CAS :D-473 is a novel orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
Formule :C26H27F2NO3Couleur et forme :SolidMasse moléculaire :439.4915-keto-Prostaglandin E2
CAS :15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression.Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45GSK852
GSK852 is a potent, second bromodomain (BD2)-selective, bromo and extra-terminal domain (BET) inhibitor with pIC50 of 7.9.Formule :C24H26N2O4Couleur et forme :SolidMasse moléculaire :406.475α-reductase-IN-1
CAS :5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase.Formule :C31H37NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.63AChE-IN-8
AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.Formule :C20H22N4O2SCouleur et forme :SolidMasse moléculaire :382.48GLP-1R agonist 8
CAS :GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Formule :C33H32N4O5Couleur et forme :SolidMasse moléculaire :564.63MK-7445
CAS :MK-7445 is a conformationally constrained inhibitor of non-nucleoside reverse transcriptase.Formule :C21H13Cl2N7OCouleur et forme :SolidMasse moléculaire :450.28PDE4-IN-6
PDE4-IN-6: Potent PDE4 inhibitor, IC50 - 0.125μM (B), 0.43μM (D), anti-inflammatory, for arthritis research.Formule :C25H20FNO5SCouleur et forme :SolidMasse moléculaire :465.49NF-κB-IN-6
NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent that works by reducing the protein expression of iNOS and COX-2 by suppressing the NF-κB signalingFormule :C14H20N2O3Couleur et forme :SolidMasse moléculaire :264.32LY 541850
CAS :LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from humanFormule :C9H13NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :199.2HR-546
CAS :HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.Formule :C26H44O6Couleur et forme :SolidMasse moléculaire :452.62Anti-Trypanosoma cruzi agent-1
Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.Formule :C23H29N3O5Couleur et forme :SolidMasse moléculaire :427.49Lentiginosine
CAS :Lentiginosine is a selective amyloglucosidase inhibitor.Formule :C8H15NO2Couleur et forme :SolidMasse moléculaire :157.21NVP-CFC218
CAS :NVP-CFC218 is a novel potent and selective p53-HDM2 inhibitor.Formule :C37H45ClN4O4Couleur et forme :SolidMasse moléculaire :645.23Isobetanin
CAS :Isobetanin is a betacyanin that has been shown to enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells.
Formule :C24H26N2O13Couleur et forme :SolidMasse moléculaire :550.47Imolamine hydrochloride
CAS :Imolamine hydrochloride is a blood platelet aggregation antagonist.Formule :C14H21ClN4OCouleur et forme :SolidMasse moléculaire :296.80Pefcalcitol
CAS :Pefcalcitol is a novel antipsoriatic prodrug candidate containing a 16-en-22-oxa-vitamin D3 structure.Formule :C26H34F5NO4Couleur et forme :SolidMasse moléculaire :519.54Macitentan (n-butyl analogue)
CAS :Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.Formule :C20H21Br2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.29Anti-Influenza agent 3
Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).Formule :C16H22ClNOSCouleur et forme :SolidMasse moléculaire :311.87EBI-1051
CAS :EBI-1051 is a highly potent and orally efficacious inhibitor of MEK (IC50: 3.9 nM).Formule :C18H15F2IN2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.22cis-4-Br-2,5-F2-PCPA
cis-4-Br-2,5-F2-PCPA (S1024) blocks LSD1/LSD2 (Ki: 94 nM/8.4 μM), hinders cancer stem cell growth, raises H3K4me2 in CCRF-CEM cells.Formule :C9H8BrF2NCouleur et forme :SolidMasse moléculaire :248.075(S),6(R)-DiHETE
CAS :5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47Macbecin I
CAS :Hsp90 inhibitorFormule :C30H42N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :558.66PPI-2458
CAS :PPI-2458, a fumagillin derivative, irreversibly blocks MetAP2, hindering abnormal cell growth and angiogenesis with improved toxicity.Formule :C22H36N2O6Couleur et forme :SolidMasse moléculaire :424.53LSD1-IN-19
LSD1-IN-19 is a potent, selective LSD1 inhibitor with Ki of 0.108 μM and 72h IC50 values of 0.17-0.40 μM.Formule :C33H42N6O2Couleur et forme :SolidMasse moléculaire :554.73Orvepitant
CAS :Orvepitant is a potent and selective NK1 antagonist, which may be potentially useful for patients with major depressive disorder (MDD), anxiety and insomnia.Formule :C31H35F7N4O2Couleur et forme :SolidMasse moléculaire :628.62PARP1-IN-5
PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.Formule :C25H24N2O5SCouleur et forme :SolidMasse moléculaire :464.53WS-898
WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.Formule :C33H25N7OSCouleur et forme :SolidMasse moléculaire :567.66α-Glucosidase-IN-13
α-Glucosidase-IN-13 is an inhibitor of α-glucosidase (IC50: 5.69 μM).Formule :C25H28N4O3S2Couleur et forme :SolidMasse moléculaire :496.64MRS4458
CAS :MRS4458 is an effective inhibitor of the P2Y14 Receptor.Formule :C24H20F3N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.51P-gp modulator 3
P-gp modulator 3 (Compound 37) is a potent, competitive, metabotropic P-glycoprotein (P-gp) modulator.Formule :C31H37N3O5Couleur et forme :SolidMasse moléculaire :531.64Anticancer agent 29
Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).Formule :C22H15ClFNOCouleur et forme :SolidMasse moléculaire :363.81PXS-5153A monohydrochloride
CAS :PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 <40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.Formule :C20H25Cl2FN4O2SDegré de pureté :98%Couleur et forme :Odour SolidMasse moléculaire :475.41SCH-1473759
CAS :SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).Formule :C20H26N8OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.54KRAS inhibitor-21
CAS :KRAS inhibitor-21 (22b) is a KRAS G12C inhibitor (IC50<0.01 μM) that can be used in cancer research.Formule :C33H41N5O3Couleur et forme :SolidMasse moléculaire :555.71Cbl-b-IN-1
CAS :Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.Formule :C29H34N6O2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :498.631RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44Tilpisertib fosmecarbil
CAS :Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.Formule :C35H36ClN8O7PCouleur et forme :SolidMasse moléculaire :747.14PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Formule :C18H20ClN3OSCouleur et forme :SolidMasse moléculaire :361.89rel-MDM2/4-p53-IN-3
rel-MDM2/4-p53-IN-3 inhibits MDM2/4-p53 PPI, IC50: MDM2 18.5nM, MDM4 14.8nM, targets cancer research.Formule :C25H24Cl2FN3O3Couleur et forme :SolidMasse moléculaire :504.38HDAC8-IN-2
HDAC8-IN-2 (5o) inhibits both smHDAC8 and hHDAC8 with IC50s of 0.27 μM, 0.32 μM, kills schistosome larvae, and lowers egg laying.Formule :C21H16N2O5Couleur et forme :SolidMasse moléculaire :376.36p38-α MAPK-IN-5
CAS :p38-α MAPK-IN-5: potent p38α inhibitor, IC50s: 0.1 nM (α), 0.2 nM (β), 944 nM (γ), 4100 nM (δ); anti-inflammatory, promising for asthma/COPD research.Formule :C37H49N11O2Couleur et forme :SolidMasse moléculaire :679.86KUSC-5037
KUSC-5037 inhibits HIF-1 (IC50 = 1.2 μM) and mitochondrial complex V/FoF1ATP synthase.Formule :C18H17F3N6O2Couleur et forme :SolidMasse moléculaire :406.13651Topoisomerase I inhibitor 8
CAS :Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.Formule :C24H21FN2O4Couleur et forme :SolidMasse moléculaire :420.43KDOAM-25 citrate
CAS :KDOAM-25 citrate inhibits KDM5A/B/C/D (IC50: 71, 19, 69, 69 nM); boosts H3K4 methylation, hinders MM1S cell growth. [1]Formule :C21H33N5O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499.51SB 243213 hydrochloride
CAS :SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormule :C22H20ClF3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.87Resolvin E2
CAS :RvE2, a bioactive lipid from the SPM family, is made from EPA and reduces inflammatory neutrophil infiltration and helps treat NAFLD and other diseases.Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.45Antitumor agent-76
CAS :Antitumor agent-76 is a water-soluble, orally active, rapid-release prodrug of Triptolide that exhibits anticancer effects.Formule :C28H36ClNO10Couleur et forme :SolidMasse moléculaire :582.04BM635 hydrochloride (1493762-74-5 free base)
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).Formule :C25H30ClFN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.97Tonapofylline
CAS :Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure research.Formule :C22H32N4O4Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :416.51FTI-2628
CAS :FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.Formule :C31H34N4O3SCouleur et forme :SolidMasse moléculaire :542.69Icariside F2
CAS :Icariside F2 modestly inhibits α-glucosidase (4.6-12%) and has antioxidant properties, plus strong NF-κB inhibition (IC50: 16.25±2.19 μM).Formule :C18H26O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.39YKL-05-093
CAS :YKL-05-093 is a alt inducible kinase (SIK) inhibitor. YKL-05-093 increases bone formation and bone mass.Formule :C35H40N6O4Couleur et forme :SolidMasse moléculaire :608.73DNA-PK-IN-9
DNA-PK-IN-9 (YK6) is a potent DNA-PK inhibitor with an IC50 of 10.47 nM, important in cancer research.Formule :C21H21N5O2Couleur et forme :SolidMasse moléculaire :375.42Py-MPB-amino-C3-PBD
CAS :Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group,with antimicrobial activity.Formule :C41H44N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.84ITK inhibitor 6
CAS :ITK inhibitor 6 selectively targets ITK, BTK, JAK3, EGFR, LCK, blocks PLCγ1 and ERK1/2 phosphorylation, and inhibits cell proliferation.Formule :C28H24F2N4O2Couleur et forme :SolidMasse moléculaire :486.51AChE/BChE-IN-1
AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.Formule :C32H35ClN6O3Couleur et forme :SolidMasse moléculaire :587.11CXCR7 modulator 2
CAS :CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13 nM.Formule :C29H42N6O3Couleur et forme :SolidMasse moléculaire :522.68AFP-07
CAS :AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.Formule :C22H29F2NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.45Carbonic anhydrase inhibitor 9
Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.Formule :C22H20BrN5O4SCouleur et forme :SolidMasse moléculaire :530.39Glutaminyl cyclases-IN-1
Glutaminyl cyclase inhibitor IsoQC-IN-1: IC50=12 nM for QC, 73 nM for isoQC; blocks CD47/SIRPα; boosts THP-1, U937 macrophage phagocytosis.Formule :C25H30N6O2SCouleur et forme :SolidMasse moléculaire :478.61GNE-203
CAS :GNE-203 is a Met inhibitor.Formule :C30H29Cl2F3N8O3Couleur et forme :SolidMasse moléculaire :677.50SMP-797 HCl
CAS :SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.Formule :C34H44ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.20Flurandrenolone Acetate
CAS :Flurandrenolone Acetate, a synthetic glucocorticoid derived from Flurandrenolide, is used to study skin issues like eczema and psoriasis.Formule :C26H35FO7Couleur et forme :SolidMasse moléculaire :478.55Tuvatidine
CAS :Tuvatidine is a histamine 2 receptor antagonist.Formule :C10H17N9O2S3Couleur et forme :SolidMasse moléculaire :391.5HPK1-IN-30
CAS :HPK1-IN-30 is a potent inhibitor of HPK1. HPK1-IN-30 has potential for cancer disease research.Formule :C25H23FN6Couleur et forme :SolidMasse moléculaire :426.49PF-06462894
CAS :PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Formule :C18H23N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.39HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.Formule :C17H13ClF3N3O3Couleur et forme :SolidMasse moléculaire :399.75Canosimibe
CAS :Canosimibe is a cholesterol absorption inhibitorFormule :C44H60FN3O10Couleur et forme :SolidMasse moléculaire :809.96Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55CHNQD-01255
CAS :CHNQD-01255 is an orally active inhibitor of Arf-GEFs that is effective against hepatocellular carcinoma (HCC).
Formule :C23H29NO6Couleur et forme :SolidMasse moléculaire :415.48HDAC-IN-34
HDAC-IN-34 inhibits HDAC1 (IC50: 0.022 μM) & HDAC6 (IC50: 0.45 μM), binds DNA causing damage, and halts HCT-116 cell growth (IC50: 1.41 μM).Formule :C24H26N6O3Couleur et forme :SolidMasse moléculaire :446.5L-Moses dihydrochloride
L-Moses (L-45) dihydrochloride is the first, potent, selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor (Kd: 126 nM).Formule :C21H26Cl2N6Couleur et forme :SolidMasse moléculaire :433.38AMPK Activator SC4
CAS :SC4 is a potent, direct AMPK activator. SC4 preferentially activates α2 complexes and stimulates skeletal muscle glucose uptake.Formule :C26H18ClN3O4Couleur et forme :SolidMasse moléculaire :471.89Adiaft
CAS :Adiaftis a bioactive chemical.Formule :C10H11IN2O4Couleur et forme :SolidMasse moléculaire :350.11BMS-751324
CAS :BMS-751324: p38α MAPK inhibitor with carbamyl-methyl, esters, phosphate from HPA. Reduces rat arthritis swelling and TNFα.Formule :C32H35N6O10PCouleur et forme :SolidMasse moléculaire :694.63BI-4916
CAS :BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.Formule :C23H24Cl2N2O6SDegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :527.42MrgprX2 antagonist-6
MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.Formule :C24H23F3N6O3Couleur et forme :SolidMasse moléculaire :500.47ZLHQ-5f
ZLHQ-5f inhibits CDK2/Topo I, with IC50 of 0.145μM for CDK2/CycA2, and promotes apoptosis by arresting HCT116 cells in S phase.Formule :C28H25N5O2Couleur et forme :SolidMasse moléculaire :463.53Homodestcardin
CAS :Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.Formule :C32H55N5O7Couleur et forme :SolidMasse moléculaire :621.81VHL Ligand 8
CAS :VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader.Formule :C23H29N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.49ETX0282
CAS :ETX0282, oral class A/C β-lactamase inhibitor, developed by Entasis with cefpodoxime for bacterial infections.Formule :C13H18FN3O5Couleur et forme :SolidMasse moléculaire :315.30PNU-248686A
CAS :PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).Formule :C22H18ClNaO5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.95Ambuic acid
CAS :Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.Formule :C19H26O6Couleur et forme :SolidMasse moléculaire :350.41SB 243213 dihydrochloride
CAS :SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 forFormule :C22H21Cl2F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.33ERα degrader 5
ERα degrader 5 is an orally active, selective estrogen receptor (ER) reducer that acts on ERα (EC50: 1.1 nM). ERα degrader 5 shows anti-tumour effects in vivo.Formule :C29H25F4N3O2SCouleur et forme :SolidMasse moléculaire :555.59
